Skip to the end: metastasis before tumorigenesis. uri icon

Overview

abstract

  • Mutations in the sodium channel NALCN promote epithelial cell shedding and dissemination independent of oncogenic transformation. This observation suggests that metastasis may not uniformly represent the end stage of carcinogenesis but can occur before oncogenic transformation.

publication date

  • December 1, 2022

Research

keywords

  • Carcinogenesis
  • Cell Transformation, Neoplastic

Identity

PubMed Central ID

  • PMC11416844

Scopus Document Identifier

  • 85141849097

Digital Object Identifier (DOI)

  • 10.1038/s41588-022-01228-3

PubMed ID

  • 36369288

Additional Document Info

volume

  • 54

issue

  • 12