Boire, Adrienne A.

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Real-world experience with circulating tumor DNA in cerebrospinal fluid from patients with central nervous system tumors. Acta neuropathologica communications. 2024 Academic Article GET IT
Why do patients with cancer die?. Nature reviews. Cancer. 2024 Review GET IT
Times cited: 1
The path to leptomeningeal metastasis. Nature reviews. Cancer. 2024 Review GET IT
The covariance environment defines cellular niches for spatial inference. Nature biotechnology. 2024 Academic Article GET IT
The anatomic basis of leptomeningeal metastasis. The Journal of experimental medicine. 2024 Review GET IT
Investigative needle core biopsies for multi-omics in Glioblastoma. 2023 GET IT
The Spectrum of Headache in Leptomeningeal Metastases: A Comprehensive Review with Clinical Management Guidelines. Current pain and headache reports. 2023 Review GET IT
Breast-to-brain metastasis is exacerbated with chemotherapy through blood-cerebrospinal fluid barrier and induces Alzheimer's-like pathology. Journal of neuroscience research. 2023 Academic Article GET IT
Cerebrospinal fluid-administered therapies for leptomeningeal metastases from solid tumors. Future oncology (London, England). 2023 Review GET IT
Leptomeningeal disease in melanoma: An update on the developments in pathophysiology and clinical care. Pigment cell & melanoma research. 2023 Review GET IT
National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research: challenges and recommended priorities. The Lancet. Oncology. 2023 Review GET IT
Leptomeningeal anti-tumor immunity follows unique signaling principles. 2023 GET IT
Dynamic Mutational Landscape of Cerebrospinal Fluid Circulating Tumor DNA and Predictors of Survival after Proton Craniospinal Irradiation for Leptomeningeal Metastases. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 7
Early Detection of Leptomeningeal Metastases Among Patients Undergoing Spinal Stereotactic Radiosurgery. Advances in radiation oncology. 2022 Academic Article GET IT
Leveraging Molecular and Immune-Based Therapies in Leptomeningeal Metastases. CNS drugs. 2022 Review GET IT
Times cited: 12
Skip to the end: metastasis before tumorigenesis. Nature genetics. 2022 Comment GET IT
Brain metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions. Neuro-oncology. 2022 Review GET IT
Times cited: 77
Discordance Between Perceptions and Experience of Lumbar Puncture: A Prospective Study. Neurology. Clinical practice. 2022 Academic Article GET IT
Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities. Pigment cell & melanoma research. 2022 Review GET IT
Times cited: 10
Randomized Phase II Trial of Proton Craniospinal Irradiation Versus Photon Involved-Field Radiotherapy for Patients With Solid Tumor Leptomeningeal Metastasis. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2022 Academic Article GET IT
Times cited: 89
Leptomeningeal Metastases: New Opportunities in the Modern Era. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2022 Review GET IT
Phenotypic and molecular states of IDH1 mutation-induced CD24-positive glioma stem-like cells. Neoplasia (New York, N.Y.). 2022 Academic Article GET IT
Times cited: 11
Incidence of brain metastases in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy with trastuzumab and pertuzumab. NPJ breast cancer. 2022 Academic Article GET IT
Times cited: 14
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients. Cell. 2022 Academic Article GET IT
Quantitative cerebrospinal fluid circulating tumor cells are a potential biomarker of response for proton craniospinal irradiation for leptomeningeal metastasis. Neuro-oncology advances. 2021 Academic Article GET IT
Advances in the diagnosis, evaluation, and management of leptomeningeal disease. Neuro-oncology advances. 2021 Academic Article GET IT
Characterization, isolation, and in vitro culture of leptomeningeal fibroblasts. Journal of neuroimmunology. 2021 Academic Article GET IT
Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination. 2021 GET IT
Times cited: 2
Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination. Cell reports. 2021 Academic Article GET IT
Times cited: 25
Clinical Experience of Cerebrospinal Fluid-Based Liquid Biopsy Demonstrates Superiority of Cell-Free DNA over Cell Pellet Genomic DNA for Molecular Profiling. The Journal of molecular diagnostics : JMD. 2021 Academic Article GET IT
Times cited: 28
Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer. Immunity. 2021 Academic Article GET IT
Times cited: 64
Clinical trial of proton craniospinal irradiation for leptomeningeal metastases. Neuro-oncology. 2021 Academic Article GET IT
Times cited: 74
Inflammatory Leptomeningeal Cytokines Mediate COVID-19 Neurologic Symptoms in Cancer Patients. Cancer cell. 2021 Academic Article GET IT
Times cited: 54
Metastasis to the Central Nervous System. Continuum (Minneapolis, Minn.). 2020 Review GET IT
Times cited: 10
Genomic Characterization of a RET Inhibitor-Resistant RET Fusion-Positive Lung Cancer by CSF Cell-Free DNA Hybrid Capture-Based Sequencing. 2020 GET IT
Palliation for all people: alleviating racial disparities in supportive care for brain metastases. Neuro-oncology. 2020 Comment GET IT
Times cited: 6
Cancer cells deploy lipocalin-2 to collect limiting iron in leptomeningeal metastasis. Science (New York, N.Y.). 2020 Academic Article GET IT
Times cited: 180
Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines. Cancer research. 2020 Review GET IT
Times cited: 68
Cerebrospinal fluid circulating tumor cells as a quantifiable measurement of leptomeningeal metastases in patients with HER2 positive cancer. Journal of neuro-oncology. 2020 Academic Article GET IT
Times cited: 61
A retrospective, quantitative assessment of disease burden in patients with leptomeningeal metastases from non-small-cell lung cancer. Neuro-oncology. 2020 Academic Article GET IT
Times cited: 42
Leptomeningeal metastatic cells adopt two phenotypic states. Cancer reports (Hoboken, N.J.). 2020 Academic Article GET IT
Times cited: 31
Leptomeningeal disease in melanoma patients: An update to treatment, challenges, and future directions. Pigment cell & melanoma research. 2020 Review GET IT
Times cited: 46
Frequency and outcomes of brain metastases in patients with HER2-mutant lung cancers. Cancer. 2019 Academic Article GET IT
Times cited: 65
Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 117
Liquid biopsy in central nervous system metastases: a RANO review and proposals for clinical applications. Neuro-oncology. 2019 Review GET IT
Times cited: 132
Author Correction: Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. 2019 GET IT
Times cited: 3
Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nature cell biology. 2018 Academic Article GET IT
Times cited: 202
The Evolving Landscape of Brain Metastasis. Trends in cancer. 2018 Review GET IT
Times cited: 199
Cerebrospinal fluid circulating tumor cells: a novel tool to diagnose leptomeningeal metastases from epithelial tumors. Neuro-oncology. 2017 Academic Article GET IT
Times cited: 95
Corrigendum: Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer. 2017 GET IT
Times cited: 9
Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis. Cell. 2017 Academic Article GET IT
Times cited: 253
Characteristics and Outcomes of Patients With Breast Cancer With Leptomeningeal Metastasis. Clinical breast cancer. 2016 Academic Article GET IT
Times cited: 92
Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer. Nature. 2016 Academic Article GET IT
Times cited: 742
Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 310
Molecular interactions in the development of brain metastases. International journal of molecular sciences. 2013 Review GET IT
Times cited: 11
Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis. Cancer research. 2009 Academic Article GET IT
Times cited: 134
Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site. Cell. 2009 Academic Article GET IT
Times cited: 221
Targeted therapy in the treatment of malignant gliomas. OncoTargets and therapy. 2009 Academic Article GET IT
Emerging therapies for malignant glioma. Expert review of anticancer therapy. 2007 Information Resource GET IT
Times cited: 13
Site-specific effects of peptide lipidation on beta-amyloid aggregation and cytotoxicity. The Journal of biological chemistry. 2007 Academic Article GET IT
Times cited: 22
Spatial separation of beta-sheet domains of beta-amyloid: disruption of each beta-sheet by N-methyl amino acids. Biochemistry. 2006 Academic Article GET IT
Times cited: 35
PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. Cell. 2005 Academic Article GET IT
Times cited: 656
Pollen recovery in atmospheric samples collected with the Rotorod Sampler over multiple-day periods such as weekends. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 1999 Academic Article GET IT
Times cited: 7
A summary of the atmospheric surveys published in the United States allergy literature, 1966-1996. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 1999 Academic Article GET IT
Times cited: 6

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Background

education and training

M.D., University of Chicago Pritzker School of Medicine 2008
Ph.D., Tufts University 2004
B.A., Macalester College 1999

Contact

full name

Adrienne A. Boire

primary email

boirea@mskcc.org

VIVO Weill Cornell Medical College

Adrienne A. Boire Associate Professor of Neurology

Publications

selected publications

Background

education and training

Contact

full name

primary email