TIM-3 and γδ T cells: new players in breast cancer dissemination. Academic Article uri icon

Overview

abstract

  • γδ T cells, a heterogeneous lymphocyte subset operating at the interface between innate and adaptive immunity, mediate ambivalent and context-dependent effects in oncological settings. Recent work by Rozalén et al, (2025) demonstrates that IL-17-secreting γδ T cells favor the outgrowth of TIM-3+ triple-negative breast cancer metastases by establishing local immunosuppression.

publication date

  • August 26, 2025

Identity

PubMed Central ID

  • PMC12489074

Scopus Document Identifier

  • 105014621499

Digital Object Identifier (DOI)

  • 10.1038/s44318-025-00550-w

PubMed ID

  • 40859036

Additional Document Info

volume

  • 44

issue

  • 19