Somatostatin release from cerebral cortical cells: influence of amino acid neurotransmitters. Academic Article uri icon

Overview

abstract

  • We examined the ability of several putative amino acid neurotransmitters to influence immunoreactive somatostatin (IRS) release from cultured rat cerebral cortical cells. The cells were exposed to either or sequential incubations in various concentrations of glutamate (Glu), aspartate (Asp), GABA, glycine, taurine and arginine. Glu and Asp were stimulatory to IRS release, whereas GABA was inhibitory. Glu-induced IRS release was calcium-dependent. Glycine and taurine were weak stimulants.

publication date

  • August 29, 1983

Research

keywords

  • Amino Acids
  • Cerebral Cortex
  • Neurotransmitter Agents
  • Receptors, Amino Acid
  • Somatostatin

Identity

Scopus Document Identifier

  • 0020618328

PubMed ID

  • 6137267

Additional Document Info

volume

  • 273

issue

  • 2