Brain research

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High-fat diet during lactation, as opposed to during adolescence or gestation, programs cardiometabolic and autonomic dysfunctions in adult offspring.. 1849. 2024
Increased brain iron deposition in the basial ganglia is associated with cognitive and motor dysfunction in type 2 diabetes mellitus.. 1846. 2024
Secondary-blast injury in rodents produces cognitive sequelae and distinct motor recovery trajectories.. 1755. 2021
Characterization of early-onset motor deficits in the Pink1-/- mouse model of Parkinson disease.. 1680. 2017
Sevoflurane and Isoflurane induce structural changes in brain vascular endothelial cells and increase blood-brain barrier permeability: Possible link to postoperative delirium and cognitive decline.. 1620. 2015
Neuronal expression of soluble adenylyl cyclase in the mammalian brain.. 1518. 2013
Longitudinal in-vivo diffusion tensor imaging for assessing brain developmental changes in BALB/cJ mice, a model of reduced sociability relevant to autism.. 1455. 2012
Electromyographic bursting following the cortical silent period induced by transcranial magnetic stimulation.. 1446. 2012
The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein.. 1436. 2011
Effects of acute post-treatment with dipyridamole in a rat model of focal cerebral ischemia.. 1373. 2010
Astaxanthin upregulates heme oxygenase-1 expression through ERK1/2 pathway and its protective effect against beta-amyloid-induced cytotoxicity in SH-SY5Y cells.. 1360. 2010
Early-life stress and neurometabolites of the hippocampus.. 1358. 2010
Distribution of estrogen receptor β containing cells in the brains of bacterial artificial chromosome transgenic mice.. 1351. 2010
Chronic restraint stress alters the expression and distribution of phosphorylated tau and MAP2 in cortex and hippocampus of rat brain.. 1347. 2010
Differential gene expression between neuropeptide Y expressing neurons of the dorsomedial nucleus of the hypothalamus and the arcuate nucleus: microarray analysis study.. 1350. 2010
Modulation of blood-brain barrier permeability by neutrophils: in vitro and in vivo studies.. 1298. 2009
Intracranial electroencephalography reveals two distinct similarity effects during item recognition.. 1299. 2009
Neural correlates of processing stressful information: an event-related fMRI study.. 1293. 2009
Tobacco smoke: a critical etiological factor for vascular impairment at the blood-brain barrier.. 1287. 2009
The Vps33a gene regulates behavior and cerebellar Purkinje cell number.. 1266. 2009
Measures of striatal insulin resistance in a 6-hydroxydopamine model of Parkinson's disease.. 1240. 2008
Efficacy of recombinant annexin 2 for fibrinolytic therapy in a rat embolic stroke model: a magnetic resonance imaging study.. 1165. 2007
Evaluation of the mGlu8 receptor as a putative therapeutic target in schizophrenia.. 1152. 2007
Gastric preloads of corn oil and mineral oil produce different patterns of increases of c-Fos-like immunoreacitve cells in the brain of 9-12 day-old rats.. 1134. 2006
Fmrp is required for the establishment of the startle response during the critical period of auditory development.. 1110. 2006
Evidence that estrogen directly and indirectly modulates C1 adrenergic bulbospinal neurons in the rostral ventrolateral medulla.. 1094. 2006
Pentylenetetrazol-induced status epilepticus up-regulates the expression of glucose transporter mRNAs but not proteins in the immature rat brain.. 1082. 2006
Electroacupuncture stimulates hypothalamic aromatization.. 1037. 2005
5-HT3A receptor subunits in the rat medial nucleus of the solitary tract: subcellular distribution and relation to the serotonin transporter.. 1028. 2004
Distinct rat neurohypophysial nerve terminal populations identified by size, electrophysiological properties and neuropeptide content.. 1024. 2004
Necrosis, apoptosis and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats.. 1022. 2004
Nicotine-mediated plasticity in robust nucleus of the archistriatum of the adult zebra finch.. 1018. 2004
Migration patterns of subventricular zone cells in adult mice change after cerebral cortex injury.. 996. 2004
Electrical stimulation of the dorsal periaqueductal gray decreases volume of the brain infarction independently of accompanying hypertension and cerebrovasodilation.. 994. 2003
Effects of chronic dizocilpine on acute pain and on mRNA expression of neuropeptides and the dopamine and glutamate receptors.. 981. 2003
L-Arginine increases ischemic injury in wild-type mice but not in iNOS-deficient mice.. 966. 2003
Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice.. 964. 2003
Delayed effect of administration of COX-2 inhibitor in mice with acute cerebral ischemia.. 960. 2003
Loss of muscarinic M4 receptors in hippocampus of Alzheimer patients.. 960. 2003
Mesotelencephalic dopamine neurochemical responses to glucocorticoid administration and adrenalectomy in Fischer 344 and Lewis rats.. 958. 2002
Stress-induced mitochondrial depolarization and oxidative damage in PSP cybrids.. 951. 2002
Amyloid precursor protein gene disruption attenuates degeneration of substantia nigra compacta neurons following axotomy.. 938. 2002
17 beta-estradiol treatment retards excitotoxic delayed degeneration in substantia nigra reticulata neurons.. 936. 2002
Evidence for endogenous agmatine in hypothalamo-neurohypophysial tract and its modulation on vasopressin release and Ca2+ channels.. 932. 2002
Stimulation of the subthalamic vasodilator area and fastigial nucleus independently protects the brain against focal ischemia.. 912. 2001
Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum.. 909. 2001
Fractionated radiation facilitates repair and functional motor recovery after spinal cord transection in rat.. 904. 2001
Differential effects of 5-HT1A receptor deletion upon basal and fluoxetine-evoked 5-HT concentrations as revealed by in vivo microdialysis.. 902. 2001
Neurons of nucleus of the solitary tract synchronize the EEG and elevate cerebral blood flow via a novel medullary area.. 892. 2001
Potassium chloride depolarization mediates CREB phosphorylation in striatal neurons in an NMDA receptor-dependent manner.. 890. 2001
Long-term changes in motor cortical organisation after recovery from subcortical stroke.. 889. 2001
Dietary restriction attenuates the neuronal loss, induction of heme oxygenase-1 and blood-brain barrier breakdown induced by impaired oxidative metabolism.. 885. 2000
Hypoxic modulation of striatal lesions induced by administration of endothelin-1.. 883. 2000
Neurotoxic APP C-terminal and beta-amyloid domains colocalize in the nuclei of substantia nigra pars reticulata neurons undergoing delayed degeneration.. 874. 2000
The role of the supplementary motor area in externally timed movement: the influence of predictability of movement timing.. 874. 2000
Gene-dosing effect and persistence of reduction in ischemic brain injury in mice lacking inducible nitric oxide synthase.. 872. 2000
Patterns of regional brain activation associated with different forms of motor learning.. 871. 2000
Role of potassium channels in the central neurogenic neuroprotection elicited by cerebellar stimulation in rat.. 842. 1999
Strain differences in mesotelencephalic dopaminergic neuronal regulation between Fischer 344 and Lewis rats.. 832. 1999
Suppression of post-ischemic-induced fos protein expression by an antisense oligonucleotide to c-fos mRNA leads to increased tissue damage.. 832. 1999
A role for KATP+-channels in mediating the elevations of cerebral blood flow and arterial pressure by hypoxic stimulation of oxygen-sensitive neurons of rostral ventrolateral medulla.. 827. 1999
Neuroprotective electrical stimulation of cerebellar fastigial nucleus attenuates expression of periinfarction depolarizing waves (PIDs) and inhibits cortical spreading depression.. 818. 1999
Temporal characteristics of the protective effect of aminoguanidine on cerebral ischemic damage.. 802. 1998
Ultrastructural localization and comparative distribution of nitric oxide synthase and N-methyl-D-aspartate receptors in the shell of the rat nucleus accumbens 1.. 796. 1998
Histological and temporal characteristics of nigral transneuronal degeneration after striatal injury.. 795. 1998
In situ PCR for in vivo detection of foreign genes transferred into rat brain.. 783. 1998
Brief electrical stimulation of cerebellar fastigial nucleus conditions long-lasting salvage from focal cerebral ischemia: conditioned central neurogenic neuroprotection.. 780. 1998
The pedunculopontine tegmental nucleus issues collaterals to the fastigial nucleus and rostral ventrolateral reticular nucleus in the rat.. 760. 1997
Melatonin administration protects CA1 hippocampal neurons after transient forebrain ischemia in rats.. 755. 1997
Ultrastructural immunocytochemical localization of the dopamine D2 receptor within GABAergic neurons of the rat striatum.. 746. 1997
Vestibular afferents to the dorsal vagal complex: substrate for vestibular-autonomic interactions in the rat.. 743. 1996
Morphology of identified corticospinal cells in the rat following motor cortex injury: absence of use-dependent change.. 714. 1996
Signal transduction for proliferation of glioma cells in vitro occurs predominantly through a protein kinase C-mediated pathway.. 710. 1996
Retrograde transfer of replication deficient recombinant adenovirus vector in the central nervous system for tracing studies.. 705. 1995
General, mu and kappa opioid antagonists in the nucleus accumbens alter food intake under deprivation, glucoprivic and palatable conditions.. 700. 1995
Cell death induced by beta-amyloid 1-40 in MES 23.5 hybrid clone: the role of nitric oxide and NMDA-gated channel activation leading to apoptosis.. 686. 1995
Accumulation of amyloid precursor protein-like immunoreactivity in rat brain in response to thiamine deficiency.. 677. 1995
Effects of funnel web spider toxin on Ca2+ currents in neurohypophysial terminals.. 663. 1994
Adrenergic and non-adrenergic spinal projections of a cardiovascular-active pressor area of medulla oblongata: quantitative topographic analysis.. 663. 1994
Central opioid receptor subtype mediation of isoproterenol-induced drinking in rats.. 657. 1994
Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia.. 651. 1994
Transient forebrain ischemia induces delayed injury in the substantia nigra reticulata: degeneration of GABA neurons, compensatory expression of GAD mRNA.. 643. 1994
Traumatic injury induces interleukin-6 production by human astrocytes.. 636. 1994
Lesions of the rostral ventrolateral medulla reduce the cerebrovascular response to hypoxia.. 635. 1994
Cell-type specific expression of Na+, K(+)-ATPase catalytic subunits in cultured neurons and glia: evidence for polarized distribution in neurons.. 631. 1993
Glutamate up-regulates alpha 1 and alpha 2 subunits of the sodium pump in astrocytes of mixed telencephalic cultures but not in pure astrocyte cultures.. 631. 1993
Modulation of acetylcholine release in rat hippocampus by amino alcohols and Bay K 8644.. 629. 1993
Effect of cervical vagotomy on catecholaminergic neurons in the cranial division of the parasympathetic nervous system.. 617. 1993
Nitric oxide synthase-containing neural processes on large cerebral arteries and cerebral microvessels.. 606. 1993
Localization of NADPH diaphorase in neurons of the rostral ventral medulla: possible role of nitric oxide in central autonomic regulation and oxygen chemoreception.. 603. 1993
Inhibition of alpha 2/alpha 3 sodium pump isoforms potentiates glutamate neurotoxicity.. 591. 1992
Early post-natal administration of 5,7-dihydroxytryptamine destroys 5-HT neurons but does not affect spatial memory.. 589. 1992
Low levels of somatostatin-like immunoreactivity in neocortex resected from presumed seizure foci in epileptic patients.. 587. 1992
In situ hybridization analysis of c-fos and c-jun expression in the rat brain following transient forebrain ischemia.. 567. 1991
Focal elevations in neocortical interstitial K+ produced by stimulation of the fastigial nucleus in rat.. 563. 1991
Saccade onset and offset lambda waves: relation to pattern movement visually evoked potentials.. 551. 1991
Blockade of morphine analgesia by both pertussis and cholera toxins in the periaqueductal gray and locus coeruleus.. 529. 1990
Effect of conditioning lesions on regeneration of goldfish optic axons: time course of the cell body reaction to axotomy.. 515. 1990
Lesions of rostral ventrolateral medulla abolish some cardio- and cerebrovascular components of the cerebellar fastigial pressor and depressor responses.. 508. 1990
Premotor negativity associated with saccadic eye movement and finger movement: a comparative study.. 506. 1990
Plasma epinephrine modulates the cerebrovasodilation evoked by electrical stimulation of dorsal medulla.. 506. 1990
Local and remote microvascular changes in excitotoxin-induced focal brain lesions.. 501. 1989
Global reduction in cerebral blood flow and metabolism elicited from intrinsic neurons of fastigial nucleus.. 500. 1989
Estradiol induces rapid remodelling of plasma membranes in developing rat cerebrocortical neurons in culture.. 498. 1989
Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy.. 495. 1989
Biochemical properties of monoamine-rich human neuroblastoma cells.. 486. 1989
Neuropeptide Y-like immunoreactivity in neurons of the solitary tract nuclei: vesicular localization and synaptic input from GABAergic terminals.. 476. 1989
Development of phorbol ester (protein kinase C) binding sites in cat visual cortex.. 470. 1988
Neuronal and endothelial sites of acetylcholine synthesis and release associated with microvessels in rat cerebral cortex: ultrastructural and neurochemical studies.. 454. 1988
The distribution and ontogenesis of [3H]nicotine binding sites in cat visual cortex.. 467. 1988
Excitatory amino acid antagonists depress acoustic startle after infusion into the ventral nucleus of the lateral lemniscus or paralemniscal zone.. 445. 1988
Transient concordant distributions of nicotinic receptors and acetylcholinesterase activity in infant rat visual cortex.. 467. 1988
Distribution of locus coeruleus axons in the rat spinal cord: a combined anterograde transport and immunohistochemical study.. 437. 1987
Benzodiazepine ([3H]flunitrazepam) binding in cat visual cortex: ontogenesis of normal characteristics and the effects of dark rearing.. 465. 1987
Serotonin axon terminals in the ventral tegmental area of the rat: fine structure and synaptic input to dopaminergic neurons.. 435. 1987
Presaccadic spike potential: a computer model based upon motor unit recruitment patterns in the extraocular muscles.. 422. 1987
Distinct influences of nerve growth factor and a central cholinergic trophic factor on medial septal explants.. 422. 1987
Stress-induced alterations in neurotensin, somatostatin and corticotropin-releasing factor in mesotelencephalic dopamine system regions.. 417. 1987
Biosynthesis of myelin-associated proteins in simian virus 40 (SV40)-transformed rat Schwann cell lines.. 414. 1987
Nicotine receptors are located on lateral geniculate nucleus terminals in cat visual cortex.. 412. 1987
Local cholinergic mechanisms participate in the increase in cortical cerebral blood flow elicited by electrical stimulation of the fastigial nucleus in rat.. 411. 1987
Phenylethanolamine N-methyltransferase-containing neurons in the rostral ventrolateral medulla. II. Synaptic relationships with GABAergic terminals.. 411. 1987
Failure to confirm report of light-evoked response of peripheral nerve to low power helium-neon laser light stimulus.. 401. 1987
Fast axonally transported proteins in regenerating goldfish optic nerve: effect of abolishing electrophysiological activity with TTX.. 400. 1987
Soluble striatal extracts enhance development of mesencephalic dopaminergic neurons in vitro.. 399. 1986
Effects of dynorphin1-13 on opiate binding and dopamine and GABA uptake in stroked cat brain.. 379. 1986
Myelination by transplanted fetal and neonatal oligodendrocytes in a dysmyelinating mutant.. 378. 1986
The hypothalamic arcuate nucleus-median eminence complex: immunohistochemistry of transmitters, peptides and DARPP-32 with special reference to coexistence in dopamine neurons.. 396. 1986
A novel vasodepressor response elicited from the rat cerebellar fastigial nucleus: the fastigial depressor response.. 370. 1986
Bromocriptine inhibits incorporation of [3H]thymidine into rat pituitary tumor cells.. 369. 1986
Muscarinic cholinergic receptors mediate the cerebrovasodilation elicited by stimulation of the cerebellar fastigial nucleus in rat.. 368. 1986
Intraocular tetrodotoxin reduces axonal transport and transcellular transfer of adenosine and other nucleosides in the visual system of goldfish.. 364. 1986
Widespread reductions in cerebral blood flow and metabolism elicited by electrical stimulation of the parabrachial nucleus in rat.. 341. 1985
Presaccadic 'spike' potential: investigation of topography and source.. 339. 1985
The effects of neurotensin, vasoactive intestinal polypeptide and other neuropeptides on the secretion of somatostatin from cerebral cortical cells.. 332. 1985
Differential morphologic effects of two fractions from fetal calf muscle on cultured chick ciliary ganglion cells.. 351. 1985
Removal of optic tectum prolongs the cell body reaction to axotomy in goldfish retinal ganglion cells.. 327. 1985
Intraocular injection of tetrodotoxin in goldfish decreases fast axonal transport of [3H]glucosamine-labeled materials in optic axons.. 299. 1984
Naloxone reversal and morphine exacerbation of neurologic deficits secondary to focal cerebral ischemia in baboons.. 290. 1984
Effect of acetoxycycloheximide and dibutyryladenosine cyclic 3':5'-monophosphate on axonal regeneration in the goldfish optic nerve.. 279. 1983
Lesions of the basal forebrain in rat selectively impair the cortical vasodilation elicited from cerebellar fastigial nucleus.. 279. 1983
Enhancement of desynchronized sleep signs after pontine microinjection of the muscarinic agonist bethanechol.. 275. 1983
Somatostatin release from cerebral cortical cells: influence of amino acid neurotransmitters.. 273. 1983
Changes in perikaryal organelles during axonal regeneration in goldfish retinal ganglion cells: an analysis of protein synthesis and routing.. 272. 1983
Global increase in cerebral metabolism and blood flow produced by focal electrical stimulation of dorsal medullary reticular formation in rat.. 272. 1983
Intraocular tetrodotoxin in goldfish hinders optic nerve regeneration.. 269. 1983
Prior collateral sprouting enhances axonal regeneration.. 269. 1983
Enhanced growth and morphological differentiation of isolated adult rat oligodendrocytes in vitro: use of a naturally produced extracellular matrix.. 267. 1983
Electrical stimulation of cerebellar fastigial nucleus increases cerebral cortical blood flow without change in local metabolism: evidence for an intrinsic system in brain for primary vasodilation.. 260. 1983
Protein synthesis and axonal transport in goldfish retinal ganglion cells during regeneration accelerated by a conditioning lesion.. 251. 1982
Enkephalin-containing neurons in substantia gelatinosa of spinal trigeminal complex: ultrastructure and synaptic interaction with primary sensory afferents.. 248. 1982
Perikaryal routing of newly synthesized proteins in regenerating neurons: quantitative electron microscopic autoradiography.. 239. 1982
Effect of nerve growth factor on regeneration of goldfish optic axons.. 238. 1982
Protein synthesis and fast axonal transport in regenerating goldfish retinal ganglion cells.. 235. 1982
Effects of neurotransmitters and cyclic AMP on somatostatin release from cultured cerebral cortical cells.. 234. 1982
The noradrenergic system in cultured aggregates of fetal rat brain cells: morphology of the aggregates and pharmacological indices of noradrenergic neurons.. 230. 1981
The relationship between extracellular amino acids and protein synthesis is altered during axonal regeneration.. 220. 1981
Effect of a conditioning lesion on optic nerve regeneration in goldfish.. 216. 1981
Monoclonal antibodies to tyrosine hydroxylase: production and characterization.. 208. 1981
Distribution of glial fibrillary acidic protein and fibronectin in primary astroglial cultures from rat brain.. 199. 1980
Effect of a conditioning lesion on regeneration of goldfish optic axons: ultrastructural evidence of enhanced outgrowth and pinocytosis.. 196. 1980
Properties of individual nerve terminal proteins identified by two-dimensional gel electrophoresis.. 185. 1980
Nerve terminal proteins of the rabbit visual relay nuclei identified by axonal transport and two-dimensional gel electrophoresis.. 168. 1979
Electron microscopic localization of substance P and enkephalin in axon terminals related to dendrites of catecholaminergic neurons.. 160. 1979
Direct excitation of neck flexor motoneurons by the interstitiospinal tract.. 160. 1979
Location of sternocleidomastoid and trapezius motoneurons in the cat.. 156. 1978
Regeneration of adrenergic axons in rat sciatic nerve: effect of a conditioning lesion.. 141. 1978
Axonal regeneration in the rat sciatic nerve: effect of a conditioning lesion and of dbcAMP.. 132. 1977
Different behavioral responses to L-DOPA after anterolateral or posterolateral hypothalamic injections of 6-hydroxydopamine.. 132. 1977
A possible role for the dorsal periventricular catecholamine bundle in stimulation produced analgesia: a behavioral and histochemical study.. 130. 1977
Immunocytochemical localization of nervous system specific protein (NSP-R) in rat brain.. 105. 1976
Attention to visual and kinesthetic components of skills.. 71. 1974
Biochemical studies of transneuronal degeneration: the effects of enucleation on the biochemical maturation of the chick optic tectum.. 67. 1974
Proliferation of norepinephrine-containing axons in rat cerebellar cortex after peduncle lesions.. 59. 1973
The role of the raphe nuclei in the regulation of ponto-geniculo-occipital wave activity.. 58. 1973
Rapid axonal transport of ( 3 H)fucosyl glycoproteins in the goldfish optic system.. 48. 1972
Protein synthesis and axonal transport in retinal ganglion cells of mice lacking visual receptors.. 44. 1972
Rapid transport of radioactivity in goldfish optic nerve following injections of labeled glucosamine.. 28. 1971
Eye movement potentials in the oculomotor and visual systems of the cat: a comparison of reserpine induced waves with those present during wakefulness and rapid eye movement sleep.. 27. 1971
Autopsy analysis of the safety, efficacy and cartography of electrical stimulation of the central gray in humans.. 371. 1986
Plasma levels of brain-derived neurotrophic factor in patients with Parkinson disease: A systematic review and meta-analysis. 2018
Epigenetic modifications in human fragile X pluripotent stem cells; Implications in fragile X syndrome modeling. 2015
Metabolism and epigenetics in the nervous system: Creating cellular fitness and resistance to neuronal death in neurological conditions via modulation of oxygen-, iron-, and 2-oxoglutarate-dependent dioxygenases. 2015
Exploring new pathways of neurodegeneration in ALS: the role of mitochondria quality control. 2014
Is schizophrenia on the autism spectrum? 2010
How the brain uses time to represent and process visual information(1). 2000

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