Teratogenic effects of antileukemic chemotherapy. Academic Article uri icon

Overview

abstract

  • The clinical teratogenicity of the new antileukemic chemotherapeutic agents administered to mothers early in the first trimester of pregnancy is not well defined. Cytarabine and thioguanine were given in identical doses to the same mother during the first trimester of two separate pregnancies. Both pregnancies resulted in viable babies, one with and one without congenital malformations. This case illustrates the highly unpredictable clinical effects on the fetus of chemotherapy early in pregnancy.

publication date

  • March 1, 1981

Research

keywords

  • Abnormalities, Drug-Induced
  • Antineoplastic Agents
  • Leukemia
  • Thumb
  • Toes

Identity

Scopus Document Identifier

  • 0019471547

PubMed ID

  • 7212895

Additional Document Info

volume

  • 141

issue

  • 4