selected publications
- RAS-mutant leukaemia stem cells drive clinical resistance to venetoclax. Nature. 2024 Academic Article GET IT
- Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap. Nature biotechnology. 2024 Academic Article GET IT
- Defining heritability, plasticity, and transition dynamics of cellular phenotypes in somatic evolution. Nature genetics. 2024 Academic Article GET IT
- Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment. Nature medicine. 2024 Academic Article GET IT
- Genotype-to-phenotype mapping of somatic clonal mosaicism via single-cell co-capture of DNA mutations and mRNA transcripts. 2024 GET IT
- Mapping genotypes to chromatin accessibility profiles in single cells. Nature. 2024 Academic Article GET IT
- Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma. Cancer cell. 2024 Academic Article GET IT
- GoT-Splice protocol for multi-omics profiling of gene expression, cell-surface proteins, mutational status, and RNA splicing in human cells. STAR protocols. 2024 Academic Article GET IT
- Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms. Cancer discovery. 2024 Academic Article GET IT
- CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue. 2024 GET IT
- SON is an essential m6A target for hematopoietic stem cell fate. Cell stem cell. 2023 Academic Article GET IT
- Cancer Evolution: A Multifaceted Affair. Cancer discovery. 2023 Academic Article GET IT
- Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization. 2023 GET IT
- Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths. Cell stem cell. 2023 Academic Article GET IT
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Epigenetic dysregulation from chromosomal transit in micronuclei.
Nature.
2023
Academic Article
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Times cited: 69 - Integration of whole transcriptome spatial profiling with protein markers. Nature biotechnology. 2023 Academic Article GET IT
- Nanobody-tethered transposition enables multifactorial chromatin profiling at single-cell resolution. Nature biotechnology. 2022 Academic Article GET IT
- Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation. Nature genetics. 2022 Academic Article GET IT
- Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction. Cell stem cell. 2022 Academic Article GET IT
- A BAX door to venetoclax resistance. Blood. 2022 Editorial Article GET IT
- Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states. Nature genetics. 2021 Academic Article GET IT
- Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia. Nature communications. 2021 Academic Article GET IT
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Smart-RRBS for single-cell methylome and transcriptome analysis.
Nature protocols.
2021
Information Resource
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Times cited: 1 -
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Molecular cell.
2021
Academic Article
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Times cited: 73 -
Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics.
Nature reviews. Genetics.
2020
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Times cited: 26 -
Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus.
Cell reports.
2020
Academic Article
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Times cited: 9 -
Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells.
Cell reports.
2020
Academic Article
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Times cited: 33 -
Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.
Nature medicine.
2020
Academic Article
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Times cited: 217 -
DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Nature genetics.
2020
Academic Article
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Times cited: 150 -
EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation.
Genome biology.
2019
Academic Article
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Times cited: 26 -
Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization.
Cell systems.
2019
Academic Article
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Times cited: 12 -
Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
Haematologica.
2019
Academic Article
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Times cited: 28 -
m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment.
Cell reports.
2019
Academic Article
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Times cited: 118 -
Somatic mutations and cell identity linked by Genotyping of Transcriptomes.
Nature.
2019
Academic Article
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Times cited: 184 -
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature.
2019
Academic Article
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Times cited: 190 -
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Nature communications.
2019
Academic Article
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Times cited: 59 -
Short telomeres are associated with inferior outcome, genomic complexity, and clonal evolution in chronic lymphocytic leukemia.
Leukemia.
2019
Academic Article
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Times cited: 18 -
Discovery of a periosteal stem cell mediating intramembranous bone formation.
Nature.
2018
Academic Article
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Times cited: 442 -
DeTiN: overcoming tumor-in-normal contamination.
Nature methods.
2018
Academic Article
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Times cited: 54 -
The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy.
Nature communications.
2017
Academic Article
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Times cited: 140 -
Resistance to checkpoint blockade therapy through inactivation of antigen presentation.
Nature communications.
2017
Academic Article
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Times cited: 672 -
Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia.
Cancer cell.
2016
Academic Article
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Times cited: 158 -
Frequent evolution of copy number alterations in CLL following first-line treatment with FC(R) is enriched with TP53 alterations: results from the CLL8 trial.
Leukemia.
2016
Article
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Times cited: 16 -
Genomic complexity of multiple myeloma and its clinical implications.
Nature reviews. Clinical oncology.
2016
Information Resource
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Times cited: 205 -
Genetic and epigenetic determinants of B-cell lymphoma evolution.
Current opinion in hematology.
2016
Information Resource
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Times cited: 3 -
Mutations driving CLL and their evolution in progression and relapse.
Nature.
2015
Academic Article
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Times cited: 834 -
Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.
Cancer cell.
2014
Academic Article
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Times cited: 287 -
Clonal evolution in hematological malignancies and therapeutic implications.
Leukemia.
2013
Information Resource
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Times cited: 125 -
In vivo activation of transferred regulatory T cells specific for third-party exogenous antigen controls GVH disease in mice.
European journal of immunology.
2013
Academic Article
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Times cited: 11 -
Mutational heterogeneity in cancer and the search for new cancer-associated genes.
Nature.
2013
Academic Article
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Times cited: 4199 -
Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics.
Genome medicine.
2013
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Times cited: 39 -
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia.
Cell.
2013
Academic Article
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Times cited: 1139 -
Depletion of T regulatory cells through selection of CD127-positive cells results in a population enriched in memory T cells: implications for anti-tumor cell therapy.
Haematologica.
2012
Academic Article
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Times cited: 10 -
Immune reconstitution is preserved in hematopoietic stem cell transplantation coadministered with regulatory T cells for GVHD prevention.
Blood.
2010
Academic Article
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Times cited: 40 -
Regulatory T cell content in the bone marrow graft does not predict the occurrence of acute GVHD.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2010
Academic Article
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Times cited: 18 -
Causes and predictive factors of mortality in a cohort of patients with hepatitis C virus-related cryoglobulinemic vasculitis treated with antiviral therapy.
The Journal of rheumatology.
2010
Academic Article
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Times cited: 46 -
Correlation of clinical and virologic responses to antiviral treatment and regulatory T cell evolution in patients with hepatitis C virus-induced mixed cryoglobulinemia vasculitis.
Arthritis and rheumatism.
2008
Academic Article
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Times cited: 33 -
The prevalence of gastrointestinal diseases in Israeli adolescents and its association with body mass index, gender, and Jewish ethnicity.
Journal of clinical gastroenterology.
2008
Academic Article
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Times cited: 12 -
Detection of occult lung impairment in welders by induced sputum particles and breath oxidation.
American journal of industrial medicine.
2008
Academic Article
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Times cited: 39 -
The B lymphocyte stimulator receptor-ligand system in hepatitis C virus-induced B cell clonal disorders.
Annals of the rheumatic diseases.
2008
Academic Article
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Times cited: 39 -
Restoration of peripheral immune homeostasis after rituximab in mixed cryoglobulinemia vasculitis.
Blood.
2008
Academic Article
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Times cited: 89 -
Relapse of hepatitis C virus-associated mixed cryoglobulinemia vasculitis in patients with sustained viral response.
Arthritis and rheumatism.
2008
Academic Article
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Times cited: 100 -
Physical examination and ECG screening in relation to echocardiography findings in young healthy adults.
Cardiology.
2007
Academic Article
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Times cited: 4 -
Medex test, a novel modality for liver disease diagnosis: a pilot study.
Journal of clinical gastroenterology.
2007
Academic Article
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Times cited: 7 -
Hepatitis C-associated mixed cryoglobulinaemia: a crossroad between autoimmunity and lymphoproliferation.
Rheumatology (Oxford, England).
2007
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Times cited: 114 -
The pathophysiology of HCV induced B-cell clonal disorders.
Autoimmunity reviews.
2007
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Times cited: 71 - Acute hepatitis C in Israel: a predominantly iatrogenic disease?. Journal of gastroenterology and hepatology. 2007 Academic Article GET IT
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Long-term survivors of childhood malignancies--aeromedical dilemmas and implications.
Aviation, space, and environmental medicine.
2006
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Times cited: 2 -
Cervical and lumbar MRI findings in aviators as a function of aircraft type.
Aviation, space, and environmental medicine.
2006
Academic Article
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Times cited: 33 - Doctors--A species on the verge of extinction? A visit to the 22nd century clinic. Medical hypotheses. 2006 Editorial Article GET IT
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PET scan as an aid for the return of a head-injured aviator to flying duty.
Aviation, space, and environmental medicine.
2006
Academic Article
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Times cited: 2 -
Streptococcus bovis bacteremia associated with acute cholecystitis.
Journal of clinical gastroenterology.
2006
Article
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Times cited: 4 -
Smoking cessation therapy and the return of aviators to flying duty.
Aviation, space, and environmental medicine.
2005
Information Resource
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Times cited: 2