selected publications
- Immune Checkpoint Inhibitor Therapy and Associations with Clonal Hematopoiesis. International journal of molecular sciences. 2024 Academic Article GET IT
- Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight. Precision clinical medicine. 2024 Academic Article GET IT
- Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones. Blood advances. 2022 Academic Article GET IT
- Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group's clinical trial E3999. Blood cancer journal. 2022 Letter GET IT
- Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia. Nature communications. 2022 Academic Article GET IT
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Matrix stiffness enhances cancer-macrophage interactions and M2-like macrophage accumulation in the breast tumor microenvironment.
Acta biomaterialia.
2022
Academic Article
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Times cited: 43 - Mutant PPM1D- and TP53-Driven Hematopoiesis Populates the Hematopoietic Compartment in Response to Peptide Receptor Radionuclide Therapy. JCO precision oncology. 2022 Academic Article GET IT
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Patient-Derived Bone Marrow Spheroids Reveal Leukemia-Initiating Cells Supported by Mesenchymal Hypoxic Niches in Pediatric B-ALL.
Frontiers in immunology.
2021
Academic Article
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Times cited: 18 -
Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia.
NPJ precision oncology.
2021
Academic Article
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Times cited: 27 - Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia. Leukemia. 2021 Academic Article GET IT
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Clonal Hematopoiesis Before, During, and After Human Spaceflight.
Cell reports.
2020
Academic Article
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Times cited: 4 -
Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration.
Cell.
2020
Information Resource
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Times cited: 15 -
Clonal Hematopoiesis and Premalignant Diseases.
Cold Spring Harbor perspectives in medicine.
2020
Review
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Times cited: 17 -
Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells.
Blood advances.
2019
Academic Article
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Times cited: 6 -
Clonal Hematopoiesis and risk of Acute Myeloid Leukemia.
Best practice & research. Clinical haematology.
2019
Information Resource
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Times cited: 7 -
Randomized trial of 10 days of decitabine ± bortezomib in untreated older patients with AML: CALGB 11002 (Alliance).
Blood advances.
2018
Academic Article
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Times cited: 40 -
Somatic mutations precede acute myeloid leukemia years before diagnosis.
Nature medicine.
2018
Academic Article
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Times cited: 490 -
Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia.
Haematologica.
2018
Academic Article
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Times cited: 37 -
Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites.
Nature.
2017
Academic Article
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Times cited: 159 -
Selection and characterization of antibody clones are critical for accurate flow cytometry-based monitoring of CD123 in acute myeloid leukemia.
Leukemia & lymphoma.
2017
Letter
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Times cited: 13 -
CD25 expression and outcomes in older patients with acute myelogenous leukemia treated with plerixafor and decitabine.
Leukemia & lymphoma.
2017
Academic Article
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Times cited: 12 -
Myelodysplastic Syndrome, Unclassifiable (MDS-U) With 1% Blasts Is a Distinct Subgroup of MDS-U With a Poor Prognosis.
American journal of clinical pathology.
2017
Academic Article
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Times cited: 15 -
Oligomonocytic chronic myelomonocytic leukemia (chronic myelomonocytic leukemia without absolute monocytosis) displays a similar clinicopathologic and mutational profile to classical chronic myelomonocytic leukemia.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2017
Academic Article
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Times cited: 33 -
The effect of initial molecular profile on response to recombinant interferon-α (rIFNα) treatment in early myelofibrosis.
Cancer.
2017
Academic Article
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Times cited: 28 -
Minimal Residual Disease Monitoring of Acute Myeloid Leukemia by Massively Multiplex Digital PCR in Patients with NPM1 Mutations.
The Journal of molecular diagnostics : JMD.
2017
Academic Article
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Times cited: 74 -
Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies.
The Journal of clinical investigation.
2017
Academic Article
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Times cited: 9 -
Minimal residual disease in acute myelogenous leukemia.
International journal of laboratory hematology.
2017
Information Resource
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Times cited: 42 -
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.
Cancer discovery.
2017
Academic Article
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Times cited: 104 -
Matrix stiffening promotes a tumor vasculature phenotype.
Proceedings of the National Academy of Sciences of the United States of America.
2016
Academic Article
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Times cited: 327 -
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Nature medicine.
2016
Academic Article
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Times cited: 305 -
Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia.
Molecular cancer therapeutics.
2014
Academic Article
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Times cited: 51 -
Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.
Experimental hematology.
2013
Academic Article
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Times cited: 35 -
Gene signature critical to cancer phenotype as a paradigm for anticancer drug discovery.
Oncogene.
2012
Academic Article
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Times cited: 5 -
Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.
Cell stem cell.
2012
Academic Article
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Times cited: 53 -
Acute myelogenous leukemia stem cells: from Bench to Bedside.
Cancer letters.
2012
Review
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Times cited: 42 -
Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways.
Blood.
2010
Academic Article
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Times cited: 71 -
Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data.
Blood.
2008
Academic Article
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Times cited: 169 -
An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.
Blood.
2007
Academic Article
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Times cited: 365 -
Tat-calpastatin fusion proteins transduce primary rat cortical neurons but do not inhibit cellular calpain activity.
Experimental neurology.
2004
Academic Article
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Times cited: 22 -
Interactions of Campylobacter jejuni cytolethal distending toxin subunits CdtA and CdtC with HeLa cells.
Infection and immunity.
2003
Academic Article
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Times cited: 106 -
Campylobacter jejuni cytolethal distending toxin promotes DNA repair responses in normal human cells.
Infection and immunity.
2003
Academic Article
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Times cited: 91 -
Cytolethal distending toxin demonstrates genotoxic activity in a yeast model.
Infection and immunity.
2001
Academic Article
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Times cited: 68