Brogi, Edi

Publications

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selected publications

Clinical and pathologic features associated with PD-L1 (SP142) expression in stromal tumor-infiltrating immune cells of triple-negative breast carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2020 Academic Article GET IT
Times cited: 25
Validation of a digital pathology system including remote review during the COVID-19 pandemic. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2020 Academic Article GET IT
Times cited: 111
The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice. The Journal of pathology. 2020 Information Resource GET IT
Times cited: 43
Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization. eLife. 2019 Academic Article GET IT
Times cited: 48
Bi-allelic alterations in DNA repair genes underpin homologous recombination DNA repair defects in breast cancer. The Journal of pathology. 2017 Academic Article GET IT
Times cited: 44
Estimating the OncotypeDX score: validation of an inexpensive estimation tool. Breast cancer research and treatment. 2016 Academic Article GET IT
Times cited: 24
Fibroepithelial Lesions in the Breast of Adolescent Females: A Clinicopathological Study of 54 Cases. The breast journal. 2016 Academic Article GET IT
Times cited: 29
IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity. Cancer research. 2016 Academic Article GET IT
Times cited: 97
The 2015 Fred W. Stewart Award: Robert H. Young, MD. The American journal of surgical pathology. 2016 Academic Article GET IT
Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy. Cancer immunology research. 2016 Academic Article GET IT
Times cited: 125
A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Academic Article GET IT
Times cited: 171
Breast carcinoma with an Oncotype Dx recurrence score <18: Rate of distant metastases in a large series with clinical follow-up. Cancer. 2016 Academic Article GET IT
Times cited: 15
Atypical Ductal Hyperplasia Bordering on Ductal Carcinoma In Situ. International journal of surgical pathology. 2016 Academic Article GET IT
Times cited: 31
PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition. Cancer cell. 2016 Academic Article GET IT
Times cited: 173
Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling. Cell. 2016 Academic Article GET IT
Times cited: 183
Breast intraductal papillomas without atypia in radiologic-pathologic concordant core-needle biopsies: Rate of upgrade to carcinoma at excision. Cancer. 2016 Academic Article GET IT
Times cited: 77
The Genomic Landscape of Male Breast Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Academic Article GET IT
Times cited: 119
Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphology. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2016 Academic Article GET IT
Times cited: 91
Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression. The Journal of pathology. 2016 Academic Article GET IT
Times cited: 106
Phyllodes tumours of the breast: a consensus review. Histopathology. 2016 Information Resource GET IT
Times cited: 324
Sentinel lymph nodes for breast carcinoma: an update on current practice. Histopathology. 2016 Information Resource GET IT
Times cited: 50
Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes & development. 2015 Academic Article GET IT
Times cited: 473
MED12 somatic mutations in fibroadenomas and phyllodes tumours of the breast. Histopathology. 2015 Academic Article GET IT
Times cited: 73
Gene expression profiling of lobular carcinoma in situ reveals candidate precursor genes for invasion. Molecular oncology. 2014 Academic Article GET IT
Times cited: 33
Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival. PloS one. 2014 Academic Article GET IT
Times cited: 75
Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S. Nature cell biology. 2014 Academic Article GET IT
Times cited: 289
In search of the ideal immunopanel to distinguish metastatic mammary carcinoma from primary lung carcinoma: a tissue microarray study of 207 cases. Applied immunohistochemistry & molecular morphology : AIMM. 2014 Academic Article GET IT
Times cited: 13
Serpins promote cancer cell survival and vascular co-option in brain metastasis. Cell. 2014 Academic Article GET IT
Times cited: 641
TGF-β-Id1 signaling opposes Twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition. Cell reports. 2013 Academic Article GET IT
Times cited: 192
Cancelled stereotactic biopsy of calcifications not seen using the stereotactic technique: do we still need to biopsy?. European radiology. 2013 Academic Article GET IT
Times cited: 5
Radioactive seed localization with 125I for nonpalpable lesions prior to breast lumpectomy and/or excisional biopsy: methodology, safety, and experience of initial year. Health physics. 2013 Academic Article GET IT
Times cited: 37
Impact of margin assessment method on positive margin rate and total volume excised. Annals of surgical oncology. 2013 Academic Article GET IT
Times cited: 29
Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma. Cell. 2013 Academic Article GET IT
Times cited: 338
Feasibility and predictability of perioperative PET and estrogen receptor ligand in patients with invasive breast cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Academic Article GET IT
Times cited: 64
Ductal carcinoma in situ: morphology-based knowledge and molecular advances. Advances in anatomic pathology. 2013 Information Resource GET IT
Times cited: 8
Safety and efficacy of radioactive seed localization with I-125 prior to lumpectomy and/or excisional biopsy. European journal of radiology. 2013 Academic Article GET IT
Times cited: 47
Immunohistochemical staining with EGFR mutation-specific antibodies: high specificity as a diagnostic marker for lung adenocarcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2013 Academic Article GET IT
Times cited: 21
Non-mammary metastases to the breast and axilla: a study of 85 cases. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2012 Academic Article GET IT
Times cited: 71
Classic lobular carcinoma in situ and atypical lobular hyperplasia at percutaneous breast core biopsy: outcomes of prospective excision. Cancer. 2012 Academic Article GET IT
Times cited: 90
DNA mismatch repair deficiency in breast carcinoma: a pilot study of triple-negative and non-triple-negative tumors. The American journal of surgical pathology. 2012 Academic Article GET IT
Times cited: 23
Papilloma diagnosed at MRI-guided vacuum-assisted breast biopsy: is surgical excision still warranted?. AJR. American journal of roentgenology. 2012 Academic Article GET IT
Times cited: 23
Should breast density influence patient selection for breast-conserving surgery?. Annals of surgical oncology. 2012 Academic Article GET IT
Times cited: 11
The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites. Cell. 2012 Academic Article GET IT
Times cited: 337
A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell. 2012 Academic Article GET IT
Times cited: 889
Id4 protein is highly expressed in triple-negative breast carcinomas: possible implications for BRCA1 downregulation. Breast cancer research and treatment. 2012 Academic Article GET IT
Times cited: 30
Favorable prognosis in patients with T1a/T1bN0 triple-negative breast cancers treated with multimodality therapy. Cancer. 2012 Academic Article GET IT
Times cited: 51
Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer. Genes & development. 2011 Academic Article GET IT
Times cited: 447
Cadherin-catenin complex dissociation in lobular neoplasia of the breast. Breast cancer research and treatment. 2011 Academic Article GET IT
Times cited: 51
Inhibition of Polo-like kinase 1 prevents the growth of metastatic breast cancer cells in the brain. Clinical & experimental metastasis. 2011 Academic Article GET IT
Times cited: 39
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. Nature medicine. 2011 Academic Article GET IT
Times cited: 696
Differentially expressed genes in window trials are influenced by the wound-healing process: lessons learned from a pilot study with anastrozole. The Journal of surgical research. 2011 Academic Article GET IT
Times cited: 13
Inflammation and increased aromatase expression occur in the breast tissue of obese women with breast cancer. Cancer prevention research (Philadelphia, Pa.). 2011 Academic Article GET IT
Times cited: 389
Breast carcinoma with brain metastases: clinical analysis and immunoprofile on tissue microarrays. Annals of oncology : official journal of the European Society for Medical Oncology. 2011 Academic Article GET IT
Times cited: 28
Intracystic papillary carcinoma of the breast: An in situ or invasive tumor? Results of immunohistochemical analysis and clinical follow-up. The American journal of surgical pathology. 2011 Academic Article GET IT
Times cited: 63
Challenges in the interpretation of breast core biopsies. The breast journal. 2010 Academic Article GET IT
Times cited: 15
Nomogram for predicting the risk of local recurrence after breast-conserving surgery for ductal carcinoma in situ. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2010 Academic Article GET IT
Times cited: 233
Subtle variations in Pten dose determine cancer susceptibility. Nature genetics. 2010 Academic Article GET IT
Times cited: 476
The influence of margin width and volume of disease near margin on benefit of radiation therapy for women with DCIS treated with breast-conserving therapy. Annals of surgery. 2010 Academic Article GET IT
Times cited: 39
An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance. Molecular cancer therapeutics. 2009 Academic Article GET IT
Times cited: 130
Lobular Carcinoma in Situ, Classical Type and Unusual Variants. Surgical pathology clinics. 2009 Information Resource GET IT
Times cited: 8
Selected reviews on topics in oncologic pathology related to tumors of the breast, gynecologic organs, and head and neck region. Archives of pathology & laboratory medicine. 2009 Article GET IT
The 2008 Fred Waldorf Stewart Award: Paul Peter Rosen, MD. The American journal of surgical pathology. 2009 Academic Article GET IT
Concurrent lobular neoplasia increases the risk of ipsilateral breast cancer recurrence in patients with ductal carcinoma in situ treated with breast-conserving therapy. Cancer. 2009 Academic Article GET IT
Times cited: 16
A phase II trial of erlotinib in combination with bevacizumab in patients with metastatic breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2008 Academic Article GET IT
Times cited: 110
Occult axillary node metastases in breast cancer are prognostically significant: results in 368 node-negative patients with 20-year follow-up. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 127
Does the benefit of sentinel node frozen section vary between patients with invasive duct, invasive lobular, and favorable histologic subtypes of breast cancer?. Annals of surgery. 2008 Academic Article GET IT
Times cited: 27
ID genes mediate tumor reinitiation during breast cancer lung metastasis. Proceedings of the National Academy of Sciences of the United States of America. 2007 Academic Article GET IT
Times cited: 219
Desmoid tumors (fibromatoses) of the breast: a 25-year experience. Annals of surgical oncology. 2007 Academic Article GET IT
Times cited: 70
Heterogenic loss of the wild-type BRCA allele in human breast tumorigenesis. Annals of surgical oncology. 2007 Academic Article GET IT
Times cited: 72
The role of sentinel lymph node biopsy in Paget's disease of the breast. Annals of surgical oncology. 2007 Academic Article GET IT
Times cited: 29
Reassessment of id1 protein expression in human mammary, prostate, and bladder cancers using a monospecific rabbit monoclonal anti-id1 antibody. Cancer research. 2006 Academic Article GET IT
Times cited: 73
Fine-needle aspiration cytology of mammary adenomyoepithelioma: a study of 12 patients. Cancer. 2006 Academic Article GET IT
Times cited: 17
Accuracy of BRCA1 and BRCA2 founder mutation analysis in formalin-fixed and paraffin-embedded (FFPE) tissue. Familial cancer. 2006 Academic Article GET IT
Times cited: 13
Id4 messenger RNA and estrogen receptor expression: inverse correlation in human normal breast epithelium and carcinoma. Human pathology. 2006 Academic Article GET IT
Times cited: 25
Carcinoid tumorlets simulate pulmonary metastases in women with breast cancer. Human pathology. 2006 Academic Article GET IT
Times cited: 23
HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism. Cancer research. 2006 Academic Article GET IT
Times cited: 81
Differential exoprotease activities confer tumor-specific serum peptidome patterns. The Journal of clinical investigation. 2006 Academic Article GET IT
Times cited: 697
Paired ductal lavage and fine-needle aspiration specimens from patients with breast carcinoma. Diagnostic cytopathology. 2005 Academic Article GET IT
Times cited: 4
Aberrant E-cadherin staining patterns in invasive mammary carcinoma. World journal of surgical oncology. 2005 Academic Article GET IT
Determination of the presence and extent of pure ductal carcinoma in situ by mammography and magnetic resonance imaging. The breast journal. 2005 Academic Article GET IT
Times cited: 174
The results of frozen section, touch preparation, and cytological smear are comparable for intraoperative examination of sentinel lymph nodes: a study in 133 breast cancer patients. Annals of surgical oncology. 2005 Academic Article GET IT
Times cited: 87
Ductal lavage in patients undergoing mastectomy for mammary carcinoma: a correlative study. Cancer. 2003 Academic Article GET IT
Times cited: 41
Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors. Proceedings of the National Academy of Sciences of the United States of America. 2003 Academic Article GET IT
Times cited: 88
Epithelial lesions in prophylactic mastectomy specimens from women with BRCA mutations. Cancer. 2003 Academic Article GET IT
Times cited: 69
Classification of benign endometrial glandular cells in cervical smears from postmenopausal women. Cancer. 2002 Academic Article GET IT
Times cited: 19
Atypical cystic lobules in patients with lobular neoplasia. International journal of surgical pathology. 2001 Academic Article GET IT
Times cited: 51
Lymphomas of the breast: pathology and clinical behavior. Seminars in oncology. 1999 Information Resource GET IT
Times cited: 154
Vascular endothelial growth factor inhibits endothelial cell apoptosis induced by tumor necrosis factor-alpha: balance between growth and death signals. Journal of molecular and cellular cardiology. 1997 Academic Article GET IT
Times cited: 185
Arterial gene transfer for therapeutic angiogenesis in patients with peripheral artery disease. Human gene therapy. 1996 Academic Article GET IT
Times cited: 140
Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression. The Journal of clinical investigation. 1996 Academic Article GET IT
Times cited: 342
Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells. The Journal of biological chemistry. 1995 Academic Article GET IT
Times cited: 421
Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only. Circulation. 1994 Academic Article GET IT
Times cited: 522
Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. The Journal of clinical investigation. 1994 Academic Article GET IT
Times cited: 1026
Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries. Association of acidic FGF with plaque microvessels and macrophages. The Journal of clinical investigation. 1993 Academic Article GET IT
Times cited: 199
Endothelin-1 and endothelin receptor mRNA expression in normal and atherosclerotic human arteries. Biochemical and biophysical research communications. 1993 Academic Article GET IT
Times cited: 196
Clinical evaluation of a novel ambulatory automatic blood pressure monitoring system. Angiology. 1990 Academic Article GET IT

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Background

education and training

Ph.D., Italian Ministry of Education, University and Research (Italy) 1994
M.D., University of Florence Faculty of Medicine and Surgery (Italy) 1988

Contact

full name

Edi Brogi

VIVO Weill Cornell Medical College

Edi Brogi Professor of Clinical Pathology and Laboratory Medicine

Publications

selected publications

Background

education and training

Contact

full name