Fung, Edward K

Publications

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selected publications

Comparison of targeting two antigens (GPA33 versus HER2) for ²²⁵Ac-pretargeted alpha-radioimmunotherapy of colorectal cancer. Theranostics. 2025 Academic Article GET IT
²²⁵Ac α-Pretargeted Radioimmunotherapy of Human Epidermal Growth Factor Receptor 2-Expressing Breast Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2025 Academic Article GET IT
GPA33-pretargeted radioimmunotherapy with mono- and bivalent DOTA-based Lu-177-labeled radiohaptens in a mouse orthotopic liver xenograft model of metastatic human colorectal cancer. Theranostics. 2025 Academic Article GET IT
Divergent neurodegeneration associations with choroid plexus volume and degree of calcification in cognitively normal APOE ε4 carriers and non-carriers. Scientific reports. 2025 Academic Article GET IT
2-[¹⁸F]Fluoropropionic Acid PET Imaging of Doxorubicin-Induced Cardiotoxicity. Molecular imaging and biology. 2025 Academic Article GET IT
High-resolution motion compensation for brain PET imaging using real-time electromagnetic motion tracking. Medical physics. 2024 Academic Article GET IT
2-[18F]Fluoropropionic Acid PET Imaging of Doxorubicin-induced Cardiotoxicity. 2024 GET IT
Bidirectional regulation of motor circuits using magnetogenetic gene therapy. Science advances. 2024 Academic Article GET IT
Theranostic GPA33-Pretargeted Radioimmunotherapy of Human Colorectal Carcinoma with a Bivalent ¹⁷⁷Lu-Labeled Radiohapten. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024 Academic Article GET IT
Brain Fluid Clearance After Traumatic Brain Injury Measured Using Dynamic Positron Emission Tomography. Neurotrauma reports. 2024 Academic Article GET IT
Positron Emission Tomography Quantitative Assessment of Off-Target Whole-Body Biodistribution of I-124-Labeled Adeno-Associated Virus Capsids Administered to Cerebral Spinal Fluid. Human gene therapy. 2023 Academic Article GET IT
Times cited: 6
Efficacy of HER2-Targeted Intraperitoneal ²²⁵Ac α-Pretargeted Radioimmunotherapy for Small-Volume Ovarian Peritoneal Carcinomatosis. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2023 Academic Article GET IT
Choroid Plexus Calcification Correlates with Cortical Microglial Activation in Humans: A Multimodal PET, CT, MRI Study. AJNR. American journal of neuroradiology. 2023 Academic Article GET IT
Times cited: 8
Monitoring the biodistribution of radiolabeled therapeutics in mice. Methods in cell biology. 2023 Academic Article GET IT
Tau PET following acute TBI: Off-target binding to blood products, tauopathy, or both?. Frontiers in neuroimaging. 2022 Academic Article GET IT
Times cited: 3
Dosimetry in radionuclide therapy: the clinical role of measuring radiation dose. The Lancet. Oncology. 2022 Review GET IT
Intraperitoneal pretargeted radioimmunotherapy for colorectal peritoneal carcinomatosis. Molecular cancer therapeutics. 2021 Academic Article GET IT
Radiation segmentectomy of hepatic metastases with Y-90 glass microspheres. Abdominal radiology (New York). 2021 Academic Article GET IT
Times cited: 2
A pilot study treatment of malignant tumors using low-dose ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG). American journal of nuclear medicine and molecular imaging. 2020 Academic Article GET IT
Quantitative Whole-Body Imaging of I-124-Labeled Adeno-Associated Viral Vector Biodistribution in Nonhuman Primates. Human gene therapy. 2020 Academic Article GET IT
Times cited: 27
IntraOmmaya compartmental radioimmunotherapy using ¹³¹I-omburtamab-pharmacokinetic modeling to optimize therapeutic index. European journal of nuclear medicine and molecular imaging. 2020 Academic Article GET IT
Alpha radioimmunotherapy using ²²⁵Ac-proteus-DOTA for solid tumors - safety at curative doses. Theranostics. 2020 Academic Article GET IT
Times cited: 34
Biodistribution and Dosimetry of Intraventricularly Administered ¹²⁴I-Omburtamab in Patients with Metastatic Leptomeningeal Tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2019 Academic Article GET IT
Times cited: 38
Theranostic pretargeted radioimmunotherapy of internalizing solid tumor antigens in human tumor xenografts in mice: Curative treatment of HER2-positive breast carcinoma. Theranostics. 2018 Academic Article GET IT
Times cited: 35
ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts. Molecular pharmaceutics. 2018 Academic Article GET IT
Times cited: 5
Curative Multicycle Radioimmunotherapy Monitored by Quantitative SPECT/CT-Based Theranostics, Using Bispecific Antibody Pretargeting Strategy in Colorectal Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Academic Article GET IT
Times cited: 38
Targeting of radiolabeled J591 antibody to PSMA-expressing tumors: optimization of imaging and therapy based on non-linear compartmental modeling. EJNMMI research. 2016 Academic Article GET IT
Times cited: 35
Theranostic pretargeted radioimmunotherapy of colorectal cancer xenografts in mice using picomolar affinity ⁸⁶Y- or ¹⁷⁷Lu-DOTA-Bn binding scFv C825/GPA33 IgG bispecific immunoconjugates. European journal of nuclear medicine and molecular imaging. 2015 Academic Article GET IT
Times cited: 39
Event-by-event respiratory motion correction for PET with 3D internal-1D external motion correlation. Medical physics. 2013 Academic Article GET IT
Times cited: 22
Cerebral blood flow with [15O]water PET studies using an image-derived input function and MR-defined carotid centerlines. Physics in medicine and biology. 2013 Academic Article GET IT
Times cited: 59
A Multimodal Approach to Image-Derived Input Functions for Brain PET. IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium. 2009 Academic Article GET IT

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Research

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Funding awarded

Quantitative cerebral oxygen metabolic imaging of acute ischemic stroke awarded by National Institute of Neurological Disorders & Stroke Co-Investigator 2024 - 2029
Theranostic Trop-2-directed pretargeted radioimmunotherapy for metastatic prostate cancer with curative intent awarded by United States Department of Defense Co-Investigator 2025 - 2028
Brain fluid clearance and misfolded protein dynamics following traumatic brain injury awarded by National Institute on Aging Co-Investigator 2023 - 2028
Development and optimization of CEACAM5-targeted alpha emitters awarded by Prostate Cancer Foundation Co-Investigator 2025 - 2027
An engineered bacterial reporter gene fusion for radiotheranostics awarded by National Cancer Institute Co-Investigator 2024 - 2026
DOTA-based pre-targeting of alpha emitters awarded by National Cancer Institute Co-Investigator 2022 - 2024

Modernization and Expansion of the Citigroup Biomedical Imaging Center at Weill Cornell Medical College awarded by National Institutes of Health, Office of the Director Key Personnel 2023 - 2027
New PET/CT System for Human and Non-human Primate Imaging awarded by National Institutes of Health, Office of the Director Key Personnel 2023 - 2025

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Background

education and training

Ph.D., Yale University 2013
M.Phil., Yale University 2009
M.S., Yale University 2008
B.S., Columbia University 2002

Contact

full name

Edward K Fung

primary email

ekf4001@med.cornell.edu

VIVO Weill Cornell Medical College

Edward K Fung Assistant Professor of Medical Physics in Radiology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email