Zhang, Haiying

Publications

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selected publications

Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2. Cell. 2025 Academic Article GET IT
Times cited: 16
Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression. Nature cancer. 2024 Academic Article GET IT
Times cited: 1
Optimization of ultracentrifugation-based method to enhance the purity and proteomic profiling depth of plasma-derived extracellular vesicles and particles. Journal of extracellular biology. 2024 Academic Article GET IT
Times cited: 2
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer. Nature medicine. 2024 Academic Article GET IT
Times cited: 33
Tumour-derived Extracellular Vesicle and Particle Reprogramming of Interstitial Macrophages in the Lung Pre-Metastatic Niche Enhances Vascular Permeability and Metastatic Potential. 2024 GET IT
Nerolidol reduces depression-like behavior in mice and suppresses microglia activation by down-regulating DNA methyltransferase 1. Neuroreport. 2024 Academic Article GET IT
Times cited: 2
Protocol for cross-platform characterization of human and murine extracellular vesicles and particles. STAR protocols. 2023 Academic Article GET IT
Times cited: 4
Tumour extracellular vesicles and particles induce liver metabolic dysfunction. Nature. 2023 Academic Article GET IT
Times cited: 162
Extracellular vesicles and particles impact the systemic landscape of cancer. The EMBO journal. 2022 Review GET IT
Times cited: 84
KRAS ^G12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2021 Academic Article GET IT
Times cited: 32
An exosome pathway without an ESCRT. Cell research. 2021 Comment GET IT
Times cited: 69
Tumour-regulated anorexia preceding cachexia. Nature cell biology. 2021 Comment GET IT
Times cited: 5
Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids. STAR protocols. 2020 Academic Article GET IT
Times cited: 27
Recent Advances in Experimental Models of Breast Cancer Exosome Secretion, Characterization and Function. Journal of mammary gland biology and neoplasia. 2020 Review GET IT
Times cited: 14
Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers. iScience. 2020 Academic Article GET IT
Times cited: 45
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. Cell. 2020 Academic Article GET IT
Times cited: 938
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis. Nature cell biology. 2019 Academic Article GET IT
Times cited: 342
Tumour vesicular micromachinery uncovered. Nature cell biology. 2019 Article GET IT
Times cited: 4
Asymmetric-flow field-flow fractionation technology for exomere and small extracellular vesicle separation and characterization. Nature protocols. 2019 Academic Article GET IT
Times cited: 378
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation. Nature cell biology. 2018 Academic Article GET IT
Times cited: 1351
Bone voyage-Osteoblasts remotely control tumors. Science (New York, N.Y.). 2017 Comment GET IT
Times cited: 3
Pre-metastatic niches: organ-specific homes for metastases. Nature reviews. Cancer. 2017 Review GET IT
Times cited: 1472
JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors. Science signaling. 2016 Academic Article GET IT
Times cited: 57
Tumour exosome integrins determine organotropic metastasis. Nature. 2015 Academic Article GET IT
Times cited: 4168
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver. Nature cell biology. 2015 Academic Article GET IT
Times cited: 2236
Double-stranded DNA in exosomes: a novel biomarker in cancer detection. Cell research. 2014 Letter GET IT
Times cited: 1416

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Research

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Funding awarded

Targeting Ovarian Cancer Metastasis: From Pre-metastatic Niches to Liquid Biopsies awarded by Pershing Square Foundation Co-Investigator 2025 - 2028
Abnormal Extracellular Vesicles and Particles from Human Islets Impact T1D progression awarded by National Institute of Diabetes & Digestive & Kidney Diseases Co-Investigator 2023 - 2028
Pancreatic Cancer Detection Consortium awarded by National Cancer Institute Co-Investigator 2022 - 2027
Targeting the Axis of Tumor-Derived Extracellular Vesicles, Lung Macrophages, and Neutrophil Extracellular Traps to Prevent Pulmonary Metastasis in Osteosarcoma awarded by Osteosarcoma Institute Co-Investigator 2024 - 2026
missing activity Co-Investigator 2023 - 2025

Application of 4D proteomics and super-resolution microscopy in extracellular vesicle and particle-borne biomarker discovery for early pancreatic cancer detection awarded by National Cancer Institute Co-Principal Investigator 2023 - 2028
missing activity Co-Principal Investigator 2019 - 2024

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Contact

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Haiying Zhang

primary email

haz2005@med.cornell.edu

VIVO Weill Cornell Medical College

Haiying Zhang Assistant Professor of Cell and Developmental Biology in Pediatrics

Publications

selected publications

Research

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Publications

selected publications

Research

Funding awarded

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primary email