Ding, Hong

Publications

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selected publications

The Effect of Different Glucose Concentrations on the Antiproliferative Activity of Metformin in MCF-7 Breast Cancer Cells. Pharmaceutics. 2023 Academic Article GET IT
3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations. Frontiers in cardiovascular medicine. 2022 Review GET IT
Metformin prevents hyperglycaemia-associated, oxidative stress-induced vascular endothelial dysfunction: essential role for the orphan nuclear receptor, Nr4a1 (Nur77).. Molecular pharmacology. 2021 Academic Article GET IT
A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan. Frontiers in endocrinology. 2021 Information Resource GET IT
A Comprehensive Review of Viral Characteristics, Transmission, Pathophysiology, Immune Response, and Management of SARS-CoV-2 and COVID-19 as a Basis for Controlling the Pandemic. Frontiers in immunology. 2021 Information Resource GET IT
Times cited: 98
A Review of the Progress and Challenges of Developing a Vaccine for COVID-19. Frontiers in immunology. 2020 Information Resource GET IT
Times cited: 337
Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy. Cancers. 2019 Academic Article GET IT
Times cited: 22
Potent and PPARα-independent anti-proliferative action of the hypolipidemic drug fenofibrate in VEGF-dependent angiosarcomas in vitro. Scientific reports. 2019 Academic Article GET IT
Times cited: 14
Exercise Alleviates Obesity-Induced Metabolic Dysfunction via Enhancing FGF21 Sensitivity in Adipose Tissues. Cell reports. 2019 Academic Article GET IT
Times cited: 37
Minimizing Hyperglycemia-Induced Vascular Endothelial Dysfunction by Inhibiting Endothelial Sodium-Glucose Cotransporter 2 and Attenuating Oxidative Stress: Implications for Treating Individuals With Type 2 Diabetes. Canadian journal of diabetes. 2019 Academic Article GET IT
Times cited: 10
Impact of currently used anti-diabetic drugs on myoendothelial communication. Current opinion in pharmacology. 2018 Information Resource GET IT
Times cited: 4
Hyperglycaemic impairment of PAR2-mediated vasodilation: Prevention by inhibition of aortic endothelial sodium-glucose-co-Transporter-2 and minimizing oxidative stress. Vascular pharmacology. 2018 Academic Article GET IT
Times cited: 43
Hyperglycaemia disrupts conducted vasodilation in the resistance vasculature of db/db mice. Vascular pharmacology. 2018 Academic Article GET IT
Times cited: 14
Metformin represses glucose starvation induced autophagic response in microvascular endothelial cells and promotes cell death. Biochemical pharmacology. 2017 Academic Article GET IT
Times cited: 22
Metformin is not just an antihyperglycaemic drug but also has protective effects on the vascular endothelium. Acta physiologica (Oxford, England). 2016 Information Resource GET IT
Times cited: 61
Molecular Interplay between microRNA-34a and Sirtuin1 in Hyperglycemia-Mediated Impaired Angiogenesis in Endothelial Cells: Effects of Metformin. The Journal of pharmacology and experimental therapeutics. 2015 Academic Article GET IT
Times cited: 55
Metformin improves endothelial function in aortic tissue and microvascular endothelial cells subjected to diabetic hyperglycaemic conditions. Biochemical pharmacology. 2015 Academic Article GET IT
Times cited: 31
Metformin: An Old Drug for the Treatment of Diabetes but a New Drug for the Protection of the Endothelium. Medical principles and practice : international journal of the Kuwait University, Health Science Centre. 2015 Information Resource GET IT
Times cited: 139
Fibroblast growth factor 21 prevents atherosclerosis by suppression of hepatic sterol regulatory element-binding protein-2 and induction of adiponectin in mice. Circulation. 2015 Academic Article GET IT
Times cited: 217
Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population. Journal of translational medicine. 2015 Academic Article GET IT
Times cited: 14
Cardiovascular impact of drugs used in the treatment of diabetes. Therapeutic advances in chronic disease. 2014 Information Resource GET IT
Times cited: 44
FGF21 maintains glucose homeostasis by mediating the cross talk between liver and brain during prolonged fasting. Diabetes. 2014 Academic Article GET IT
Times cited: 140
Luteolin inhibits smooth muscle cell migration and proliferation by attenuating the production of Nox4, p-Akt and VEGF in endothelial cells. Current pharmaceutical biotechnology. 2014 Academic Article GET IT
Times cited: 13
Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1. British journal of pharmacology. 2014 Academic Article GET IT
Times cited: 179
Luteolin inhibits angiotensin II-induced human umbilical vein endothelial cell proliferation and migration through downregulation of Src and Akt phosphorylation. Circulation journal : official journal of the Japanese Circulation Society. 2012 Academic Article GET IT
Times cited: 22
The contribution of d-tubocurarine-sensitive and apamin-sensitive K-channels to EDHF-mediated relaxation of mesenteric arteries from eNOS-/- mice. Journal of cardiovascular pharmacology. 2012 Academic Article GET IT
Times cited: 1
Endothelial dysfunction in diabetes mellitus: possible involvement of endoplasmic reticulum stress?. Experimental diabetes research. 2012 Information Resource GET IT
Times cited: 101
Perivascular adipose tissue-derived relaxing factors: release by peptide agonists via proteinase-activated receptor-2 (PAR2) and non-PAR2 mechanisms. British journal of pharmacology. 2011 Academic Article GET IT
Times cited: 17
Increased expression of the tail-anchored membrane protein SLMAP in adipose tissue from type 2 Tally Ho diabetic mice. Experimental diabetes research. 2011 Academic Article GET IT
Times cited: 9
A review of endothelial dysfunction in diabetes: a focus on the contribution of a dysfunctional eNOS. Journal of the American Society of Hypertension : JASH. 2010 Information Resource GET IT
Times cited: 68
Endothelial dysfunction in diabetes: multiple targets for treatment. Pflugers Archiv : European journal of physiology. 2010 Information Resource GET IT
Times cited: 81
High glucose increases expression of cyclooxygenase-2, increases oxidative stress and decreases the generation of nitric oxide in mouse microvessel endothelial cells. Journal of cellular physiology. 2010 Academic Article GET IT
Times cited: 47
Glucose enhances expression of TRPC1 and calcium entry in endothelial cells. American journal of physiology. Heart and circulatory physiology. 2009 Academic Article GET IT
Times cited: 38
Endothelium-dependent vasodilation in myogenically active mouse skeletal muscle arterioles: role of EDH and K(+) channels. Microcirculation (New York, N.Y. : 1994). 2009 Academic Article GET IT
Times cited: 18
Effects of a Western diet versus high glucose on endothelium-dependent relaxation in murine micro- and macro-vasculature. European journal of pharmacology. 2008 Academic Article GET IT
Oxidative stress and increased eNOS and NADPH oxidase expression in mouse microvessel endothelial cells. Journal of cellular physiology. 2007 Academic Article GET IT
Times cited: 77
Vascular dysfunction in type 2 diabetic TallyHo mice: role for an increase in the contribution of PGH2/TxA2 receptor activation and cytochrome p450 products. Canadian journal of physiology and pharmacology. 2007 Academic Article GET IT
Times cited: 19
Increased oxidative stress in the streptozotocin-induced diabetic apoE-deficient mouse: changes in expression of NADPH oxidase subunits and eNOS. European journal of pharmacology. 2007 Academic Article GET IT
Times cited: 62
Calcium-activated potassium channel and connexin expression in small mesenteric arteries from eNOS-deficient (eNOS-/-) and eNOS-expressing (eNOS+/+) mice. European journal of pharmacology. 2007 Academic Article GET IT
Times cited: 17
Nitrosothiol stores in vascular tissue: modulation by ultraviolet light, acetylcholine and ionomycin. European journal of pharmacology. 2007 Academic Article GET IT
Pharmacological characteristics of endothelium-derived hyperpolarizing factor-mediated relaxation of small mesenteric arteries from db/db mice. European journal of pharmacology. 2006 Academic Article GET IT
Times cited: 44
Endothelial dysfunction in the streptozotocin-induced diabetic apoE-deficient mouse. British journal of pharmacology. 2005 Academic Article GET IT
Times cited: 87
Twenty-five years since the discovery of endothelium-derived relaxing factor (EDRF): does a dysfunctional endothelium contribute to the development of type 2 diabetes?. Canadian journal of physiology and pharmacology. 2005 Information Resource GET IT
Times cited: 21
Endothelial dysfunction in Type 2 diabetes correlates with deregulated expression of the tail-anchored membrane protein SLMAP. American journal of physiology. Heart and circulatory physiology. 2005 Academic Article GET IT
Times cited: 16
Endothelial cell dysfunction and the vascular complications associated with type 2 diabetes: assessing the health of the endothelium. Vascular health and risk management. 2005 Information Resource GET IT
Times cited: 98
The endothelium in health and disease: a discussion of the contribution of non-nitric oxide endothelium-derived vasoactive mediators to vascular homeostasis in normal vessels and in type II diabetes. Molecular and cellular biochemistry. 2004 Information Resource GET IT
Times cited: 31
The endothelium in health and disease--a target for therapeutic intervention. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi. 2003 Information Resource GET IT
Times cited: 88
Endothelium-derived relaxing factors: a focus on endothelium-derived hyperpolarizing factor(s). Canadian journal of physiology and pharmacology. 2001 Information Resource GET IT
Times cited: 154
Potassium- and acetylcholine-induced vasorelaxation in mice lacking endothelial nitric oxide synthase. British journal of pharmacology. 2000 Academic Article GET IT
Acetylcholine-induced relaxation of peripheral arteries isolated from mice lacking endothelial nitric oxide synthase. British journal of pharmacology. 1999 Academic Article GET IT
Times cited: 116

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Background

education and training

Ph.D., University of Calgary (Canada) 2001
B.M., Zhejiang Medical University (China) 1989

Contact

full name

Hong Ding

primary email

hod2005@qatar-med.cornell.edu

VIVO Weill Cornell Medical College

Hong Ding Associate Professor of Research in Pharmacology

Publications

selected publications

Background

education and training

Contact

full name

primary email