Zippin, Jonathan

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selected publications

Genome-Wide Insights Into the Genes and Pathways Shaping Human Foveal Development: Redefining the Genetic Landscape of Foveal Hypoplasia. Investigative ophthalmology & visual science. 2025 Academic Article GET IT
Genome-Wide Insights into the Genes and Pathways Shaping Human Foveal Development. 2025 GET IT
Updated expert opinion guidelines regarding the effects of immunosuppressive agents on patch testing. Journal of the American Academy of Dermatology. 2025 Academic Article GET IT
The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus. eLife. 2024 Academic Article GET IT
Times cited: 3
Two-pore channel 2 is required for soluble adenylyl cyclase-dependent regulation of melanosomal pH and melanin synthesis. Pigment cell & melanoma research. 2024 Academic Article GET IT
Times cited: 3
A randomized trial of a wearable UV dosimeter for skin cancer prevention. Frontiers in medicine. 2024 Academic Article GET IT
Times cited: 4
Photodermatoses in patients with atopic dermatitis: A 10-year retrospective cohort study. Journal of the American Academy of Dermatology. 2024 Academic Article GET IT
Type I hypersensitivity in photoallergic contact dermatitis. 2023 GET IT
Phase Ib Trial of Phenformin in Patients with V600-mutated Melanoma Receiving Dabrafenib and Trametinib. Cancer research communications. 2023 Academic Article GET IT
Times cited: 5
Tumour extracellular vesicles and particles induce liver metabolic dysfunction. Nature. 2023 Academic Article GET IT
Times cited: 165
Distinct cAMP Signaling Microdomains Differentially Regulate Melanosomal pH and Pigmentation. The Journal of investigative dermatology. 2023 Academic Article GET IT
Times cited: 5
Soluble adenylyl cyclase contributes to imiquimod-mediated inflammation and is a potential therapeutic target in psoriasis. Experimental dermatology. 2023 Academic Article GET IT
Times cited: 1
The Prevalence of Type IV Hypersensitivity in Patients With Lichen Planopilaris and Frontal Fibrosing Alopecia. Dermatitis : contact, atopic, occupational, drug. 2023 Letter GET IT
Times cited: 4
The impact of cancer history on the prevalence of type IV hypersensitivity: A 9-year matched retrospective cohort study. Journal of the American Academy of Dermatology. 2022 Academic Article GET IT
The potential impact of melanosomal pH and metabolism on melanoma. Frontiers in oncology. 2022 Review GET IT
Times cited: 2
Cell-intrinsic melanin fails to protect melanocytes from ultraviolet-mutagenesis in the absence of epidermal melanin. Pigment cell & melanoma research. 2022 Academic Article GET IT
Times cited: 5
A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation. Cell reports. 2022 Academic Article GET IT
Times cited: 7
Contact Allergy Cross-reactions and Thresholds: A Review. Dermatitis : contact, atopic, occupational, drug. 2022 Review GET IT
Times cited: 6
Histone 3 Methyltransferases Alter Melanoma Initiation and Progression Through Discrete Mechanisms. Frontiers in cell and developmental biology. 2022 Academic Article GET IT
Times cited: 5
Computational Investigation of the pH Dependence of Stability of Melanosome Proteins: Implication for Melanosome formation and Disease. International journal of molecular sciences. 2021 Academic Article GET IT
Times cited: 5
Chemical and biochemical control of skin pigmentation with special emphasis on mixed melanogenesis. Pigment cell & melanoma research. 2021 Review GET IT
Times cited: 57
Facial Personal Protective Equipment: Materials, Resterilization Methods, and Management of Occupation-Related Dermatoses. Dermatitis : contact, atopic, occupational, drug. 2021 Academic Article GET IT
Times cited: 1
Measurement of Melanin Metabolism in Live Cells by [U-¹³C]-L-Tyrosine Fate Tracing Using Liquid Chromatography-Mass Spectrometry. The Journal of investigative dermatology. 2021 Academic Article GET IT
Times cited: 15
Defining Fragrance Allergy in the Contact Allergen Management Program. Dermatitis : contact, atopic, occupational, drug. 2021 Letter GET IT
Times cited: 1
Clinical, Endoscopic, and Histologic Benefit With Comprehensive Type IV Hypersensitivity Patch Testing in Adults With Eosinophilic Esophagitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2020 Academic Article GET IT
Times cited: 2
Occupational dermatitis to facial personal protective equipment in health care workers: A systematic review. Journal of the American Academy of Dermatology. 2020 Academic Article GET IT
Times cited: 83
Cyclic adenosine monophosphate (cAMP) signaling in melanocyte pigmentation and melanomagenesis. Pigment cell & melanoma research. 2020 Review GET IT
Times cited: 3
Multi-omic analysis reveals significantly mutated genes and DDX3X as a sex-specific tumor suppressor in cutaneous melanoma. Nature cancer. 2020 Academic Article GET IT
Times cited: 34
Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid. The Journal of experimental medicine. 2020 Academic Article GET IT
Times cited: 74
Defining Topical Corticosteroids by Allergenicity and Cross-Reactivity for the Contact Allergen Management Program. Dermatitis : contact, atopic, occupational, drug. 2020 Letter GET IT
Times cited: 2
Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH. Science signaling. 2018 Academic Article GET IT
Times cited: 34
Trends and Scope of Dermatology Procedures Billed by Advanced Practice Professionals From 2012 Through 2015. JAMA dermatology. 2018 Academic Article GET IT
Times cited: 22
Ultraviolet radiation accelerates NRas-mutant melanomagenesis: A cooperative effect blocked by sunscreen. Pigment cell & melanoma research. 2017 Academic Article GET IT
Times cited: 14
Phenformin Enhances the Efficacy of ERK Inhibition in NF1-Mutant Melanoma. The Journal of investigative dermatology. 2017 Academic Article GET IT
Times cited: 20
Stoma care products represent a common and previously underreported source of peristomal contact dermatitis. Contact dermatitis. 2016 Academic Article GET IT
Times cited: 45
Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase. Nature chemical biology. 2016 Academic Article GET IT
Times cited: 71
The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein. Oncotarget. 2016 Academic Article GET IT
Times cited: 17
Pediatric Contact Dermatitis Registry Inaugural Case Data. Dermatitis : contact, atopic, occupational, drug. 2016 Academic Article GET IT
Times cited: 32
Investigation of cAMP microdomains as a path to novel cancer diagnostics. Biochimica et biophysica acta. 2014 Review GET IT
Times cited: 16
Double-positive CD4(+)CD8(+) Sézary syndrome: an unusual phenotype with an aggressive clinical course. 2014 GET IT
Times cited: 7
Surgical Management of Primary Cutaneous Cryptococcosis after Failed Medical Management. 2014 GET IT
Allergic contact dermatitis to cosmetics. Dermatologic clinics. 2014 Review GET IT
Times cited: 32
Allergic contact dermatitis to timolol: a report of 2 cases and review of the literature. Dermatitis : contact, atopic, occupational, drug. 2014 Letter GET IT
Times cited: 3
Cutaneous Cryptococcoma in a Patient on TNF-α Inhibition. Journal of clinical medicine. 2013 Academic Article GET IT
Times cited: 4
CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor. The Journal of biological chemistry. 2013 Academic Article GET IT
Times cited: 103
Type 10 soluble adenylyl cyclase is overexpressed in prostate carcinoma and controls proliferation of prostate cancer cells. The Journal of biological chemistry. 2012 Academic Article GET IT
Times cited: 46
Expression of soluble adenylyl cyclase in lentigo maligna: use of immunohistochemistry with anti-soluble adenylyl cyclase antibody (R21) in diagnosis of lentigo maligna and assessment of margins. Archives of pathology & laboratory medicine. 2012 Academic Article GET IT
Times cited: 26
Allergic contact dermatitis and cosmetics. Cutis. 2012 Academic Article GET IT
Times cited: 4
Soluble adenylyl cyclase antibody profile as a diagnostic adjunct in the assessment of pigmented lesions. Archives of dermatology. 2011 Academic Article GET IT
Times cited: 33
Soluble adenylyl cyclase defines a nuclear cAMP microdomain in keratinocyte hyperproliferative skin diseases. The Journal of investigative dermatology. 2010 Academic Article GET IT
Times cited: 46
Current treatments for infantile hemangiomas. Journal of drugs in dermatology : JDD. 2010 Review GET IT
Times cited: 20
Cutaneous T-cell lymphoma: a review of current therapies and the future therapeutic implications of chemokine biology. Journal of drugs in dermatology : JDD. 2009 Review GET IT
Times cited: 2
Nanotechnology in cosmetics and sunscreens: an update. Journal of drugs in dermatology : JDD. 2009 Article GET IT
Times cited: 6
Alpha-melanocyte stimulating hormone analogues: the perils and the promise. Journal of drugs in dermatology : JDD. 2009 Review GET IT
Times cited: 1
From bench to bedside: the therapeutic potential of nitric oxide in dermatology. Journal of drugs in dermatology : JDD. 2009 Review GET IT
Times cited: 12
The genetics of psoriasis. Journal of drugs in dermatology : JDD. 2009 Review GET IT
Times cited: 6
Androgenetic alopecia: diagnosis and treatment with a focus on recent genetic implications. Journal of drugs in dermatology : JDD. 2009 Review GET IT
Times cited: 5
Varicella virus and the herpes zoster vaccine. A review of Zostavax and the new AFIP recommendations. Journal of drugs in dermatology : JDD. 2008 Article GET IT
Times cited: 3
When wound healing goes awry. A review of normal and abnormal wound healing, scar pathophysiology, and therapeutics. Journal of drugs in dermatology : JDD. 2008 Review GET IT
Times cited: 8
Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells. The Journal of general physiology. 2008 Academic Article GET IT
Times cited: 101
Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones. Nature neuroscience. 2006 Academic Article GET IT
Times cited: 92
Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1. The Journal of biological chemistry. 2006 Academic Article GET IT
Times cited: 65
The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization. Developmental cell. 2005 Academic Article GET IT
Times cited: 364
Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain. The Journal of cell biology. 2004 Academic Article GET IT
Times cited: 152
Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2002 Academic Article GET IT
Times cited: 222
CO(2)/HCO(3)(-)-responsive soluble adenylyl cyclase as a putative metabolic sensor. Trends in endocrinology and metabolism: TEM. 2001 Review GET IT
Times cited: 89
Importance of the N terminus of rous sarcoma virus protease for structure and enzymatic function. Journal of virology. 2001 Academic Article GET IT
Times cited: 11

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Research

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Co-investigator Network

Funding awarded

Examination of sAC inhibitors as a method to treat oculocutaneous albinism awarded by Vision of Children Foundation Principal Investigator 2025 - 2027
Evaluation of Vitamin C in melanocytes awarded by L''Oreal USA Principal Investigator 2023 - 2026
missing activity Principal Investigator 2023 - 2026
Mechanisms Of Camp-Dependent Regulation Of Melanosome Ph awarded by National Inst of Arthritis & Musculoskeletal & Skin Diseases Principal Investigator 2021 - 2026
missing activity Principal Investigator 2024 - 2025

missing activity Key Personnel 2023 - 2024

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Background

education and training

Ph.D., Weill Cornell Graduate School of Medical Sciences 2205
M.D., Weill Cornell Medical College, Cornell University 2006
B.S., Cornell University 1998

Contact

full name

Jonathan Zippin

primary email

jhzippin@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Jonathan Zippin Associate Professor of Dermatology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage