selected publications
- Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue. Nature communications. 2024 Academic Article GET IT
- Prevention and treatment of peri-implant fibrosis by functionally inhibiting skeletal cells expressing the leptin receptor. Nature biomedical engineering. 2024 Academic Article GET IT
- Effects of antiseptic irrigation solutions on osseointegration in a cementless tibial implantation mouse model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2024 Academic Article GET IT
- Langerhans cells regulate immunity in adulthood by regulating postnatal dermal lymphatic development. 2024 GET IT
- Another Notch in the Belt of Rheumatoid Arthritis. Arthritis & rheumatology (Hoboken, N.J.). 2024 Review GET IT
- Staphyloccocus aureus biofilm, in absence of planktonic bacteria, produces factors that activate counterbalancing inflammatory and immune-suppressive genes in human monocytes. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2024 Academic Article GET IT
- A translational murine model of aseptic loosening with osseointegration failure. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2024 Academic Article GET IT
- Interferons and epigenetic mechanisms in training, priming and tolerance of monocytes and hematopoietic progenitors. Immunological reviews. 2024 Review GET IT
- The 2023 Orthopaedic Research Society's International Consensus Meeting on musculoskeletal infection: Summary from the host immunity section. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2023 Academic Article GET IT
- Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function. 2023 GET IT
- TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance. The Journal of experimental medicine. 2023 Academic Article GET IT
- Dichotomous roles of RIPK3 in regulating the IFN response and NLRP3 inflammasome in human monocytes. Journal of leukocyte biology. 2023 Academic Article GET IT
- Expressions of Concern: Reprogramming of IL-10 Activity and Signaling by IFN-γ. 2023 GET IT
- Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis. 2022 GET IT
- Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19. Science immunology. 2022 Academic Article GET IT
-
CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes.
Nature communications.
2022
Academic Article
GET IT
Times cited: 23 - Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation. The Journal of experimental medicine. 2022 Academic Article GET IT
-
Distinct Inflammatory Macrophage Populations Sequentially Infiltrate Bone-to-Tendon Interface Tissue After Anterior Cruciate Ligament (ACL) Reconstruction Surgery in Mice.
JBMR plus.
2022
Academic Article
GET IT
Times cited: 8 - RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis. 2022 GET IT
- Intermittent parathyroid hormone increases stability and improves osseointegration of initially unstable implants. Bone & joint research. 2022 Academic Article GET IT
-
Role of Lysine-Specific Demethylase 1 in Metabolically Integrating Osteoclast Differentiation and Inflammatory Bone Resorption Through Hypoxia-Inducible Factor 1α and E2F1.
Arthritis & rheumatology (Hoboken, N.J.).
2022
Academic Article
GET IT
Times cited: 27 - Computational pathology for musculoskeletal conditions using machine learning: advances, trends, and challenges. Arthritis research & therapy. 2022 Review GET IT
- Immune Response to Persistent Staphyloccocus aureus Periprosthetic Joint Infection in a Mouse Tibial Implant Model. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2021 Academic Article GET IT
- RNA-seq Analysis of Peri-Implant Tissue Shows Differences in Immune, Notch, Wnt, and Angiogenesis Pathways in Aged Versus Young Mice. JBMR plus. 2021 Academic Article GET IT
- Sequencing of Circulating Microbial Cell-Free DNA Can Identify Pathogens in Periprosthetic Joint Infections. The Journal of bone and joint surgery. American volume. 2021 Academic Article GET IT
- Inhibition of PAD4 mediated neutrophil extracellular traps prevents fibrotic osseointegration failure in a tibial implant murine model : an animal study. The bone & joint journal. 2021 Academic Article GET IT
- Immune and repair responses in joint tissues and lymph nodes after knee arthroplasty surgery in mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2021 Academic Article GET IT
- In vitro responses to platelet-rich-plasma are associated with variable clinical outcomes in patients with knee osteoarthritis. Scientific reports. 2021 Academic Article GET IT
- Tmem100- and Acta2-Lineage Cells Contribute to Implant Osseointegration in a Mouse Model. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2021 Academic Article GET IT
-
MEF2C regulates osteoclastogenesis and pathologic bone resorption via c-FOS.
Bone research.
2021
Academic Article
GET IT
Times cited: 37 -
Implication of the Association of Fibrinogen Citrullination and Osteoclastogenesis in Bone Destruction in Rheumatoid Arthritis.
Cells.
2020
Academic Article
GET IT
Times cited: 10 -
The hypoxia-lactate axis tempers inflammation.
Nature reviews. Immunology.
2020
Academic Article
GET IT
Times cited: 183 -
Interferon target-gene expression and epigenomic signatures in health and disease.
Nature immunology.
2019
Review
GET IT
Times cited: 327 -
IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate macrophage activation.
Nature communications.
2019
Academic Article
GET IT
Times cited: 63 -
The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair.
Immunity.
2019
Academic Article
GET IT
Times cited: 97 -
Vascular endothelial growth factor pathway promotes osseointegration and CD31hiEMCNhi endothelium expansion in a mouse tibial implant model: an animal study.
The bone & joint journal.
2019
Academic Article
GET IT
Times cited: 23 -
Insights into rheumatic diseases from next-generation sequencing.
Nature reviews. Rheumatology.
2019
Information Resource
GET IT
Times cited: 28 -
TNF-induced inflammatory genes escape repression in fibroblast-like synoviocytes: transcriptomic and epigenomic analysis.
Annals of the rheumatic diseases.
2019
Academic Article
GET IT
Times cited: 74 -
HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness.
Science translational medicine.
2019
Academic Article
GET IT
Times cited: 145 -
IFNγ: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy.
Nature reviews. Immunology.
2018
Information Resource
GET IT
Times cited: 768 -
Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue.
Arthritis research & therapy.
2018
Academic Article
GET IT
Times cited: 81 -
Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data.
Arthritis & rheumatology (Hoboken, N.J.).
2018
Academic Article
GET IT
Times cited: 136 -
Regulation of age-associated B cells by IRF5 in systemic autoimmunity.
Nature immunology.
2018
Academic Article
GET IT
Times cited: 101 -
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis.
Nature communications.
2018
Academic Article
GET IT
Times cited: 371 -
Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation.
Nature communications.
2018
Academic Article
GET IT
Times cited: 244 -
Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models.
Nature communications.
2018
Academic Article
GET IT
Times cited: 27 -
Type I interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation.
Nature immunology.
2017
Academic Article
GET IT
Times cited: 176 -
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF.
Immunity.
2017
Academic Article
GET IT
Times cited: 128 -
Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis.
Immunity.
2017
Academic Article
GET IT
Times cited: 72 -
Tumor Necrosis Factor dynamically regulates the mRNA stabilome in rheumatoid arthritis fibroblast-like synoviocytes.
PloS one.
2017
Academic Article
GET IT
Times cited: 19 -
Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.
Journal of immunology (Baltimore, Md. : 1950).
2017
Academic Article
GET IT
Times cited: 15 -
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.
Nature.
2017
Academic Article
GET IT
Times cited: 738 -
IFN-γ Induces Histone 3 Lysine 27 Trimethylation in a Small Subset of Promoters to Stably Silence Gene Expression in Human Macrophages.
Cell reports.
2016
Academic Article
GET IT
Times cited: 69 -
Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages.
Scientific reports.
2016
Academic Article
GET IT
Times cited: 26 -
RBP-J-Regulated miR-182 Promotes TNF-α-Induced Osteoclastogenesis.
Journal of immunology (Baltimore, Md. : 1950).
2016
Academic Article
GET IT
Times cited: 61 -
Cutting Edge: EZH2 Promotes Osteoclastogenesis by Epigenetic Silencing of the Negative Regulator IRF8.
Journal of immunology (Baltimore, Md. : 1950).
2016
Academic Article
GET IT
Times cited: 61 -
RBP-J is required for M2 macrophage polarization in response to chitin and mediates expression of a subset of M2 genes.
Protein & cell.
2016
Academic Article
GET IT
Times cited: 39 -
Intravenous Immunoglobulin (IVIG) Attenuates TNF-Induced Pathologic Bone Resorption and Suppresses Osteoclastogenesis by Inducing A20 Expression.
Journal of cellular physiology.
2016
Academic Article
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Times cited: 18 -
Use of RNA sequencing to evaluate rheumatic disease patients.
Arthritis research & therapy.
2015
Information Resource
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Times cited: 24 -
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation.
Nature immunology.
2015
Academic Article
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Times cited: 216 -
Prolonged tumor necrosis factor α primes fibroblast-like synoviocytes in a gene-specific manner by altering chromatin.
Arthritis & rheumatology (Hoboken, N.J.).
2015
Academic Article
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Times cited: 61 -
BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak-STAT signaling in a gene-specific manner in human monocytes.
European journal of immunology.
2014
Academic Article
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Times cited: 67 -
Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation.
Nature communications.
2014
Academic Article
GET IT
Times cited: 110 -
RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis.
The Journal of clinical investigation.
2014
Academic Article
GET IT
Times cited: 58 -
Modulation of TNF-induced macrophage polarization by synovial fibroblasts.
Journal of immunology (Baltimore, Md. : 1950).
2014
Academic Article
GET IT
Times cited: 83 -
Regulation of type I interferon responses.
Nature reviews. Immunology.
2014
Information Resource
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Times cited: 2281 -
Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling.
Immunity.
2013
Academic Article
GET IT
Times cited: 233 -
Kinase inhibitors: a new tool for the treatment of rheumatoid arthritis.
Clinical immunology (Orlando, Fla.).
2013
Information Resource
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Times cited: 27 -
Tumor necrosis factor α induces sustained signaling and a prolonged and unremitting inflammatory response in rheumatoid arthritis synovial fibroblasts.
Arthritis and rheumatism.
2013
Academic Article
GET IT
Times cited: 121 -
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.
The Journal of clinical investigation.
2013
Academic Article
GET IT
Times cited: 144 -
Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
2013
Academic Article
GET IT
Times cited: 47 -
Epigenetic regulation of macrophage polarization and function.
Trends in immunology.
2012
Information Resource
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Times cited: 303 -
Regulation of inflammatory responses in tumor necrosis factor-activated and rheumatoid arthritis synovial macrophages by JAK inhibitors.
Arthritis and rheumatism.
2012
Academic Article
GET IT
Times cited: 102 -
The interferon signature and STAT1 expression in rheumatoid arthritis synovial fluid macrophages are induced by tumor necrosis factor α and counter-regulated by the synovial fluid microenvironment.
Arthritis and rheumatism.
2012
Academic Article
GET IT
Times cited: 51 -
Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.
Nature immunology.
2012
Academic Article
GET IT
Times cited: 359 -
ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes.
Journal of immunology (Baltimore, Md. : 1950).
2012
Academic Article
GET IT
Times cited: 24 -
TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J.
The Journal of experimental medicine.
2012
Academic Article
GET IT
Times cited: 161 -
Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors.
Arthritis research & therapy.
2011
Information Resource
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Times cited: 117 -
Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages.
Nature immunology.
2011
Academic Article
GET IT
Times cited: 149 -
A unique hybrid renal mononuclear phagocyte activation phenotype in murine systemic lupus erythematosus nephritis.
Journal of immunology (Baltimore, Md. : 1950).
2011
Academic Article
GET IT
Times cited: 122 -
Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3K-Akt-GSK3 pathway.
Immunology.
2011
Academic Article
GET IT
Times cited: 75 -
TNF activates calcium-nuclear factor of activated T cells (NFAT)c1 signaling pathways in human macrophages.
Proceedings of the National Academy of Sciences of the United States of America.
2011
Academic Article
GET IT
Times cited: 119 -
Systemic lupus erythematosus monocytes are less responsive to interleukin-10 in the presence of immune complexes.
Arthritis and rheumatism.
2011
Academic Article
GET IT
Times cited: 24 -
IFN-γ abrogates endotoxin tolerance by facilitating Toll-like receptor-induced chromatin remodeling.
Proceedings of the National Academy of Sciences of the United States of America.
2010
Academic Article
GET IT
Times cited: 122 -
Suppression of TNF-α and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27.
Journal of immunology (Baltimore, Md. : 1950).
2010
Academic Article
GET IT
Times cited: 68 -
Direct inhibition of human RANK+ osteoclast precursors identifies a homeostatic function of IL-1beta.
Journal of immunology (Baltimore, Md. : 1950).
2010
Academic Article
GET IT
Times cited: 35 -
Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation.
Breast cancer research : BCR.
2010
Academic Article
GET IT
Times cited: 70 -
Downregulation of Friend leukemia virus integration 1 as a feedback mechanism that restrains lipopolysaccharide induction of matrix metalloproteases and interleukin-10 in human macrophages.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
2010
Academic Article
GET IT
Times cited: 14 -
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1.
Journal of immunology (Baltimore, Md. : 1950).
2010
Academic Article
GET IT
Times cited: 100 -
STAT activation during viral infection in vivo: where's the interferon?.
Cell host & microbe.
2010
Comment
GET IT
Times cited: 5 -
The type I interferon signaling pathway is a target for glucocorticoid inhibition.
Molecular and cellular biology.
2010
Academic Article
GET IT
Times cited: 114 -
The relative timing of exposure to phagocytosable particulates and to osteoclastogenic cytokines is critically important in the determination of myeloid cell fate.
Journal of immunology (Baltimore, Md. : 1950).
2010
Academic Article
GET IT
Times cited: 9 -
Calcium-activated pathways and oxidative burst mediate zymosan-induced signaling and IL-10 production in human macrophages.
Journal of immunology (Baltimore, Md. : 1950).
2010
Academic Article
GET IT
Times cited: 81 -
Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.
Immunity.
2010
Academic Article
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Times cited: 120 -
Type I interferon: a new player in TNF signaling.
Current directions in autoimmunity.
2010
Information Resource
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Times cited: 51 -
Interleukin-27 inhibits human osteoclastogenesis by abrogating RANKL-mediated induction of nuclear factor of activated T cells c1 and suppressing proximal RANK signaling.
Arthritis and rheumatism.
2010
Academic Article
GET IT
Times cited: 80 -
Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages.
Proceedings of the National Academy of Sciences of the United States of America.
2010
Academic Article
GET IT
Times cited: 126 -
Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN-gamma in human osteoclast precursors.
Journal of immunology (Baltimore, Md. : 1950).
2009
Academic Article
GET IT
Times cited: 131 -
Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases.
Immunity.
2009
Information Resource
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Times cited: 701 -
Targeting cytokines in inflammatory diseases: focus on interleukin-1-mediated autoinflammation.
F1000 biology reports.
2009
Academic Article
GET IT
Times cited: 58 -
Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis.
Nature medicine.
2009
Academic Article
GET IT
Times cited: 259 -
IL-10 suppresses calcium-mediated costimulation of receptor activator NF-kappa B signaling during human osteoclast differentiation by inhibiting TREM-2 expression.
Journal of immunology (Baltimore, Md. : 1950).
2009
Academic Article
GET IT
Times cited: 105 -
Cross-regulation of signaling by ITAM-associated receptors.
Nature immunology.
2009
Information Resource
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Times cited: 182 -
Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.
Human immunology.
2009
Academic Article
GET IT
Times cited: 88 -
Roles of semaphorins in the immune and hematopoietic system.
Rheumatology international.
2009
Information Resource
GET IT
Times cited: 7 -
Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms.
Immunological reviews.
2008
Information Resource
GET IT
Times cited: 231 -
Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways.
Immunity.
2008
Academic Article
GET IT
Times cited: 218 -
A signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways.
Nature reviews. Immunology.
2008
Information Resource
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Times cited: 67 -
Lipopolysaccharide-induced expression of matrix metalloproteinases in human monocytes is suppressed by IFN-gamma via superinduction of ATF-3 and suppression of AP-1.
Journal of immunology (Baltimore, Md. : 1950).
2008
Academic Article
GET IT
Times cited: 61 -
Regulation of STAT pathways and IRF1 during human dendritic cell maturation by TNF-alpha and PGE2.
Journal of leukocyte biology.
2008
Academic Article
GET IT
Times cited: 22 -
IFN-gamma and STAT1 arrest monocyte migration and modulate RAC/CDC42 pathways.
Journal of immunology (Baltimore, Md. : 1950).
2008
Academic Article
GET IT
Times cited: 49 -
IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38.
Journal of immunology (Baltimore, Md. : 1950).
2008
Academic Article
GET IT
Times cited: 93 -
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes.
Nature immunology.
2008
Academic Article
GET IT
Times cited: 282 -
Insoluble immune complexes are most effective at triggering IL-10 production in human monocytes and synergize with TLR ligands and C5a.
Clinical immunology (Orlando, Fla.).
2008
Academic Article
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Times cited: 15 -
Expression profiling reveals alternative macrophage activation and impaired osteogenesis in periprosthetic osteolysis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
2008
Academic Article
GET IT
Times cited: 70 -
'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages.
Nature immunology.
2007
Academic Article
GET IT
Times cited: 63 -
Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation.
Journal of leukocyte biology.
2007
Information Resource
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Times cited: 188 -
A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells.
The Journal of biological chemistry.
2007
Academic Article
GET IT
Times cited: 84 -
Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs.
Journal of immunology (Baltimore, Md. : 1950).
2007
Academic Article
GET IT
Times cited: 58 -
Apoptotic cells inhibit LPS-induced cytokine and chemokine production and IFN responses in macrophages.
Human immunology.
2007
Academic Article
GET IT
Times cited: 46 -
FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin.
Immunity.
2007
Academic Article
GET IT
Times cited: 127 -
Involvement of complement receptor 3 (CR3) and scavenger receptor in macrophage responses to wear debris.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
2006
Academic Article
GET IT
Times cited: 23 -
Dysregulation of interleukin-10-dependent gene expression in rheumatoid arthritis synovial macrophages.
Arthritis and rheumatism.
2006
Academic Article
GET IT
Times cited: 49 -
Twist mediates suppression of inflammation by type I IFNs and Axl.
The Journal of experimental medicine.
2006
Academic Article
GET IT
Times cited: 206 -
Glucocorticoid modulation of cytokine signaling.
Tissue antigens.
2006
Information Resource
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Times cited: 106 -
Costimulation of chemokine receptor signaling by matrix metalloproteinase-9 mediates enhanced migration of IFN-alpha dendritic cells.
Journal of immunology (Baltimore, Md. : 1950).
2006
Academic Article
GET IT
Times cited: 48 -
IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins.
Immunity.
2006
Academic Article
GET IT
Times cited: 290 -
Selective regulation of IL-10 signaling and function by zymosan.
Journal of immunology (Baltimore, Md. : 1950).
2006
Academic Article
GET IT
Times cited: 41 -
Wear debris inhibition of anti-osteoclastogenic signaling by interleukin-6 and interferon-gamma. Mechanistic insights and implications for periprosthetic osteolysis.
The Journal of bone and joint surgery. American volume.
2006
Academic Article
GET IT
Times cited: 71 -
Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation.
The Journal of biological chemistry.
2006
Academic Article
GET IT
Times cited: 202 -
TLR2 and MyD88 contribute to Lactobacillus casei extract-induced focal coronary arteritis in a mouse model of Kawasaki disease.
Circulation.
2005
Academic Article
GET IT
Times cited: 64 -
The conserved Leu-724 residue is required for both serine phosphorylation and co-activator recruitment for Stat1-mediated transcription activation in response to interferon-gamma.
The Journal of biological chemistry.
2005
Academic Article
GET IT
Times cited: 10 -
IFN-gamma-primed macrophages exhibit increased CCR2-dependent migration and altered IFN-gamma responses mediated by Stat1.
Journal of immunology (Baltimore, Md. : 1950).
2005
Academic Article
GET IT
Times cited: 46 -
Inhibition of IFN-alpha signaling by a PKC- and protein tyrosine phosphatase SHP-2-dependent pathway.
Proceedings of the National Academy of Sciences of the United States of America.
2005
Academic Article
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Times cited: 47 -
Homeostatic role of interferons conferred by inhibition of IL-1-mediated inflammation and tissue destruction.
Journal of immunology (Baltimore, Md. : 1950).
2005
Academic Article
GET IT
Times cited: 41 -
Kinetics of IL-10-induced gene expression in human macrophages.
Immunobiology.
2005
Academic Article
GET IT
Times cited: 22 -
Regulation of macrophage phenotype by long-term exposure to IL-10.
Immunobiology.
2005
Academic Article
GET IT
Times cited: 44 -
Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors.
Nature immunology.
2004
Academic Article
GET IT
Times cited: 76 -
Signaling by STATs.
Arthritis research & therapy.
2004
Information Resource
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Times cited: 132 -
IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis.
Journal of immunology (Baltimore, Md. : 1950).
2004
Academic Article
GET IT
Times cited: 106 -
Type I interferon modulation of cellular responses to cytokines and infectious pathogens: potential role in SLE pathogenesis.
Autoimmunity.
2003
Information Resource
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Times cited: 52 -
Reprogramming of IL-10 activity and signaling by IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950).
2003
Academic Article
GET IT
Times cited: 97 -
The JAK/STAT pathway in rheumatoid arthritis: pathogenic or protective?.
Arthritis and rheumatism.
2003
Editorial Article
GET IT
Times cited: 86 -
Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis.
The Journal of experimental medicine.
2003
Academic Article
GET IT
Times cited: 65 -
Inhibition of IFN-gamma signaling by glucocorticoids.
Journal of immunology (Baltimore, Md. : 1950).
2003
Academic Article
GET IT
Times cited: 113 -
Can SOCS make arthritis better?.
The Journal of clinical investigation.
2003
Article
GET IT
Times cited: 17 -
Rheumatoid arthritis synoviocyte survival is dependent on Stat3.
Journal of immunology (Baltimore, Md. : 1950).
2002
Academic Article
GET IT
Times cited: 111 -
Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation.
Nature immunology.
2002
Academic Article
GET IT
Times cited: 168 -
Inhibition of IL-6 signaling by a p38-dependent pathway occurs in the absence of new protein synthesis.
Journal of leukocyte biology.
2002
Academic Article
GET IT
Times cited: 38 -
Cross-talk between IL-1 and IL-6 signaling pathways in rheumatoid arthritis synovial fibroblasts.
Journal of immunology (Baltimore, Md. : 1950).
2001
Academic Article
GET IT
Times cited: 76 -
Inhibition of IL-6 and IL-10 signaling and Stat activation by inflammatory and stress pathways.
Journal of immunology (Baltimore, Md. : 1950).
2000
Academic Article
GET IT
Times cited: 112 -
Circulating human B cells that express surrogate light chains and edited receptors.
Nature immunology.
2000
Academic Article
GET IT
Times cited: 99 -
Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids.
Proceedings of the National Academy of Sciences of the United States of America.
2000
Academic Article
GET IT
Times cited: 126 -
Jak-STAT signaling pathways in cells of the immune system.
Reviews in immunogenetics.
2000
Information Resource
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Times cited: 53 -
Inhibition of interleukin 2 signaling and signal transducer and activator of transcription (STAT)5 activation during T cell receptor-mediated feedback inhibition of T cell expansion.
The Journal of experimental medicine.
1999
Academic Article
GET IT
Times cited: 64 -
IL-4 selectively inhibits IL-2-triggered Stat5 activation, but not proliferation, in human T cells.
Journal of immunology (Baltimore, Md. : 1950).
1999
Academic Article
GET IT
Times cited: 37 -
Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases.
Proceedings of the National Academy of Sciences of the United States of America.
1998
Academic Article
GET IT
Times cited: 211 - Distinct signaling pathways inhibit cytokines by inhibiting jak-stat activation. FASEB Journal. 1996 Article
- Regulation of stat-1 activity during t-cell activation and differentiation into th1/th2 phenotypes. FASEB Journal. 1996 Article
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Inhibition of cytokines and JAK-STAT activation by distinct signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America.
1996
Academic Article
GET IT
Times cited: 115 -
Inhibition of transcription factor Stat1 activity in mononuclear cell cultures and T cells by the cyclic AMP signaling pathway.
Journal of immunology (Baltimore, Md. : 1950).
1996
Academic Article
GET IT
Times cited: 34 -
Cytokine expression and cell activation in inflammatory arthritis.
Advances in immunology.
1996
Information Resource
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Times cited: 77 -
Regulation of the balance of cytokine production and the signal transducer and activator of transcription (STAT) transcription factor activity by cytokines and inflammatory synovial fluids.
The Journal of experimental medicine.
1995
Academic Article
GET IT
Times cited: 68 - Repression of Constitutive and Interferon-gamma-Induced Class II Major Histocompatibility Complex Genes by Cyclic AMP and Prostaglandins. American journal of therapeutics. 1995 Academic Article GET IT
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Activation of monocyte effector genes and STAT family transcription factors by inflammatory synovial fluid is independent of interferon gamma.
The Journal of experimental medicine.
1995
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Times cited: 56 -
Inhibition of IFN-gamma induction of class II MHC genes by cAMP and prostaglandins.
Immunopharmacology.
1994
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Times cited: 26 -
Dominant negative mutants of transcription factor mXBP (CRE-BP1, ATF-2).
The New biologist.
1992
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Times cited: 9 -
Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements.
The Journal of experimental medicine.
1991
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Times cited: 32 -
Non-consensus DNA sequences function in a cell-type-specific enhancer of the mouse class II MHC gene A alpha.
International immunology.
1991
Academic Article
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Times cited: 4 -
A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain.
Molecular and cellular biology.
1990
Academic Article
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Times cited: 94 -
mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element.
Molecular and cellular biology.
1990
Academic Article
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Times cited: 229 -
Mutations in signal sequence cleavage domain of preproparathyroid hormone alter protein translocation, signal sequence cleavage, and membrane-binding properties.
Molecular endocrinology (Baltimore, Md.).
1989
Academic Article
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Times cited: 12