selected publications
- Resistance to PRMT5 Targeted Therapy in Mantle Cell Lymphoma. Blood advances. 2023 Academic Article GET IT
- PRMT5 Inhibition Drives Therapeutic Vulnerability to Combination Treatment with BCL-2 Inhibition in Mantle Cell Lymphoma. Blood advances. 2023 Academic Article GET IT
- PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma. Blood. 2023 Academic Article GET IT
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A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas.
The Journal of clinical investigation.
2022
Academic Article
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Times cited: 6 -
Radiotherapy Delivered before CDK4/6 Inhibitors Mediates Superior Therapeutic Effects in ER+ Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2021
Academic Article
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Times cited: 46 - Cell Cycle Dysregulation in Mantle Cell Lymphoma: Genomics and Therapy. Hematology/oncology clinics of North America. 2020 Information Resource GET IT
- Targeting CDK4/6 in mantle cell lymphoma. Annals of lymphoma. 2020 Academic Article GET IT
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A phase I trial of palbociclib plus bortezomib in previously treated mantle cell lymphoma.
Leukemia & lymphoma.
2019
Academic Article
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Times cited: 11 -
A phase 1 trial of ibrutinib plus palbociclib in previously treated mantle cell lymphoma.
Blood.
2019
Academic Article
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Times cited: 63 -
Cellular Proliferation by Multiplex Immunohistochemistry Identifies High-Risk Multiple Myeloma in Newly Diagnosed, Treatment-Naive Patients.
Clinical lymphoma, myeloma & leukemia.
2017
Academic Article
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Times cited: 7 -
Unification of de novo and acquired ibrutinib resistance in mantle cell lymphoma.
Nature communications.
2017
Academic Article
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Times cited: 119 -
Postibrutinib outcomes in patients with mantle cell lymphoma.
Blood.
2016
Academic Article
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Times cited: 143 -
Phase 1/2 study of cyclin-dependent kinase (CDK)4/6 inhibitor palbociclib (PD-0332991) with bortezomib and dexamethasone in relapsed/refractory multiple myeloma.
Leukemia & lymphoma.
2015
Academic Article
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Times cited: 49 -
CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity.
Cancer research.
2015
Academic Article
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Times cited: 43 -
Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma.
Cancer discovery.
2014
Academic Article
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Times cited: 238 -
Induction of prolonged early G1 arrest by CDK4/CDK6 inhibition reprograms lymphoma cells for durable PI3Kδ inhibition through PIK3IP1.
Cell cycle (Georgetown, Tex.).
2013
Academic Article
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Times cited: 68 -
Prolonged early G(1) arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle-coupled loss of IRF4.
Blood.
2012
Academic Article
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Times cited: 72 -
MAGE-A inhibits apoptosis in proliferating myeloma cells through repression of Bax and maintenance of survivin.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2011
Academic Article
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Times cited: 88 -
CDK2 phosphorylation of Smad2 disrupts TGF-beta transcriptional regulation in resistant primary bone marrow myeloma cells.
Journal of immunology (Baltimore, Md. : 1950).
2009
Academic Article
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Times cited: 30 -
Outcome of deferred initial therapy in mantle-cell lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2009
Academic Article
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Times cited: 254 -
A novel therapeutic combination using PD 0332991 and bortezomib: study in the 5T33MM myeloma model.
Cancer research.
2008
Academic Article
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Times cited: 92 -
A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6.
Cancer research.
2006
Academic Article
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Times cited: 180 -
Mutually exclusive cyclin-dependent kinase 4/cyclin D1 and cyclin-dependent kinase 6/cyclin D2 pairing inactivates retinoblastoma protein and promotes cell cycle dysregulation in multiple myeloma.
Cancer research.
2005
Academic Article
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Times cited: 90 -
Dynamic transport of SNARE proteins in the Golgi apparatus.
Proceedings of the National Academy of Sciences of the United States of America.
2005
Academic Article
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Times cited: 27 -
Concerted auto-regulation in yeast endosomal t-SNAREs.
The Journal of biological chemistry.
2005
Academic Article
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Times cited: 12 -
Homeostatic cell-cycle control by BLyS: Induction of cell-cycle entry but not G1/S transition in opposition to p18INK4c and p27Kip1.
Proceedings of the National Academy of Sciences of the United States of America.
2004
Academic Article
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Times cited: 52 -
Brain perfusion abnormalities in patients with euthyroid autoimmune thyroiditis.
European journal of nuclear medicine and molecular imaging.
2004
Academic Article
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Times cited: 42 -
Countercurrent distribution of two distinct SNARE complexes mediating transport within the Golgi stack.
Molecular biology of the cell.
2004
Academic Article
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Times cited: 78 -
Tumor necrosis factor alpha inhibits type I collagen synthesis through repressive CCAAT/enhancer-binding proteins.
Molecular and cellular biology.
2000
Academic Article
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Times cited: 148 -
A transcription activator with restricted tissue distribution regulates cell-specific expression of alpha1(XI) collagen.
The Journal of biological chemistry.
1997
Academic Article
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Times cited: 12 -
Comparative analysis of fibrillar and basement membrane collagen expression in embryos of the sea urchin, Strongylocentrotus purpuratus.
Zoological science.
1997
Academic Article
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Times cited: 13 -
Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK.
Science (New York, N.Y.).
1997
Academic Article
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Times cited: 402 -
Overlapping pathways mediate the opposing actions of tumor necrosis factor-alpha and transforming growth factor-beta on alpha 2(I) collagen gene transcription.
The Journal of biological chemistry.
1995
Academic Article
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Times cited: 104 -
Complete primary structure of a sea urchin type IV collagen alpha chain and analysis of the 5' end of its gene.
The Journal of biological chemistry.
1993
Academic Article
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Times cited: 36 -
Pro-alpha 2(V) collagen gene; pairwise analysis of the amino-propeptide coding domain, and cross-species comparison of the promoter sequence.
Connective tissue research.
1993
Academic Article
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Times cited: 5 -
Identification of an upstream regulatory region essential for cell type-specific transcription of the pro-alpha 2(V) collagen gene (COL5A2).
The Journal of biological chemistry.
1992
Academic Article
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Times cited: 24 -
Complex and diversified regulatory programs control the expression of vertebrate collagen genes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
1990
Information Resource
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Times cited: 82 -
Analysis of the promoter region and the N-propeptide domain of the human pro alpha 2(I) collagen gene.
Nucleic acids research.
1985
Academic Article
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Times cited: 29 - Releasing effect of thymidine on G1 phase arrest of erythroleukemia cells caused by FUDR and HMBA. Zhongguo yao li xue bao = Acta pharmacologica Sinica. 1984 Academic Article GET IT
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Analysis of the 3' end of the human pro-alpha 2(I) collagen gene. Utilization of multiple polyadenylation sites in cultured fibroblasts.
The Journal of biological chemistry.
1983
Academic Article
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Times cited: 91 -
Studies on the structure and possible function of the RNA "cap" in developing sea urchins.
Cell differentiation.
1977
Academic Article
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Times cited: 3