Lyu, Mengze

Publications

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The emerging family of RORγt⁺ antigen-presenting cells. Nature reviews. Immunology. 2023 Review GET IT
Times cited: 523
Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection. Cell. 2022 Academic Article GET IT
Times cited: 35
ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut. Nature. 2022 Academic Article GET IT
Group 3 innate lymphoid cells produce the growth factor HB-EGF to protect the intestine from TNF-mediated inflammation. Nature immunology. 2022 Academic Article GET IT
Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer. Cell. 2021 Academic Article GET IT
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy. Cell research. 2020 Academic Article GET IT
Times cited: 355
Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses. Immunity. 2018 Academic Article GET IT
Times cited: 151

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Co-investigator Network

Defining mechanisms of immune tolerance to the intestinal microbiota awarded by Crohn''s & Colitis Foundation of America, Inc. Principal Investigator 2023 - 2025

Innate immune regulation of neuroinflammation awarded by National Institute of Allergy & Infectious Diseases Key Personnel 2021 - 2026