Berger, Michael

selected publications

Multiomic profiling identifies predictors of survival in African American patients with acute myeloid leukemia. Nature genetics. 2024 Academic Article GET IT
Times cited: 17
Clinicogenomic predictors of outcomes in patients with hepatocellular carcinoma treated with immunotherapy. The oncologist. 2024 Academic Article GET IT
Times cited: 5
Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies. Haematologica. 2024 Academic Article GET IT
Times cited: 9
Universal germline genetic testing in patients with hematologic malignancies using DNA isolated from nail clippings. Haematologica. 2024 Article GET IT
Times cited: 8
Real-world experience with circulating tumor DNA in cerebrospinal fluid from patients with central nervous system tumors. Acta neuropathologica communications. 2024 Academic Article GET IT
Times cited: 18
Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2024 Academic Article GET IT
Times cited: 43
Tumor suppressor heterozygosity and homologous recombination deficiency mediate resistance to front-line therapy in breast cancer. bioRxiv : the preprint server for biology. 2024 Article GET IT
Tracking clonal evolution of drug resistance in ovarian cancer patients by exploiting structural variants in cfDNA. bioRxiv : the preprint server for biology. 2024 Article GET IT
DNA liquid biopsy-based prediction of cancer-associated venous thromboembolism. Nature medicine. 2024 Academic Article GET IT
Times cited: 23
Early On-Treatment Assessment of T Cells, Cytokines, and Tumor DNA with Adaptively Dosed Nivolumab + Ipilimumab: Final Results from the Phase 2 ADAPT-IT Study. Clinical cancer research : an official journal of the American Association for Cancer Research. 2024 Academic Article GET IT
Times cited: 6
Maximizing the clinical utility and performance of cytology samples for comprehensive genetic profiling - A report on the impact of process optimization through the analysis of 4,871 cytology samples profiled by MSK-IMPACT. Research square. 2024 Article GET IT
Precision oncology: current and future platforms for treatment selection. Trends in cancer. 2024 Information Resource GET IT
Times cited: 12
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment. Nature medicine. 2024 Academic Article GET IT
Times cited: 84
Genomic Landscape of Adenocarcinomas Across the Gastroesophageal Junction: Moving on From the Siewert Classification. Annals of surgery. 2024 Academic Article GET IT
Times cited: 10
Deep-Learning Model for Tumor-Type Prediction Using Targeted Clinical Genomic Sequencing Data. Cancer discovery. 2024 Academic Article GET IT
Times cited: 24
Serial Cell-Free DNA Sequencing in ROS1 Fusion-Positive Lung Cancers During Treatment With Entrectinib. JCO precision oncology. 2024 Academic Article GET IT
Natural History and Genomic Landscape of Chemotherapy-Resistant Muscle-Invasive Bladder Cancer. JCO precision oncology. 2024 Academic Article GET IT
Times cited: 2
Clinical utility of plasma cell-free DNA in pancreatic neuroendocrine neoplasms. Endocrine-related cancer. 2024 Academic Article GET IT
Times cited: 5
High-risk and silent clonal hematopoietic genotypes in patients with nonhematologic cancer. Blood advances. 2024 Academic Article GET IT
Times cited: 12
Convergent evolution of BRCA2 reversion mutations under therapeutic pressure by PARP inhibition and platinum chemotherapy. NPJ precision oncology. 2024 Academic Article GET IT
Times cited: 13
Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer. Cancer discovery. 2024 Academic Article GET IT
Times cited: 257
Standard-of-care systemic therapy with or without stereotactic body radiotherapy in patients with oligoprogressive breast cancer or non-small-cell lung cancer (Consolidative Use of Radiotherapy to Block [CURB] oligoprogression): an open-label, randomised, controlled, phase 2 study. Lancet (London, England). 2023 Academic Article GET IT
Times cited: 232
Pathogenic germline variants in non-BRCA1/2 homologous recombination genes in ovarian cancer: Analysis of tumor phenotype and survival. Gynecologic oncology. 2023 Academic Article GET IT
Times cited: 17
Assessing the Genomic Landscape of Cervical Cancers: Clinical Opportunities and Therapeutic Targets. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 13
Clinical and Genomic Landscape of FGFR3-Altered Urothelial Carcinoma and Treatment Outcomes with Erdafitinib: A Real-World Experience. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 50
Molecular Characterization of Endometrial Carcinomas in Black and White Patients Reveals Disparate Drivers with Therapeutic Implications. Cancer discovery. 2023 Academic Article GET IT
Times cited: 37
Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing. Nature communications. 2023 Academic Article GET IT
Times cited: 23
Pathogenic germline variants in patients with endometrial cancer of diverse ancestry. Cancer. 2023 Academic Article GET IT
Times cited: 10
Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers. Cancer cell. 2023 Academic Article GET IT
Times cited: 29
Genomic ancestry in kidney cancer: Correlations with clinical and molecular features. Cancer. 2023 Academic Article GET IT
Times cited: 9
Neoplasia risk in patients with Lynch syndrome treated with immune checkpoint blockade. Nature medicine. 2023 Academic Article GET IT
Times cited: 27
Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data. medRxiv : the preprint server for health sciences. 2023 Article GET IT
First-line regorafenib with nivolumab and chemotherapy in advanced oesophageal, gastric, or gastro-oesophageal junction cancer in the USA: a single-arm, single-centre, phase 2 trial. The Lancet. Oncology. 2023 Academic Article GET IT
Times cited: 40
Germline Pathogenic Variants and Genetic Counseling by Ancestry in Patients With Epithelial Ovarian Cancer. JCO precision oncology. 2023 Academic Article GET IT
Times cited: 8
Targeted Molecular Profiling of Circulating Cell-Free DNA in Patients With Advanced Hepatocellular Carcinoma. JCO precision oncology. 2023 Academic Article GET IT
Times cited: 13
Genomic Profiling Reveals Germline Predisposition and Homologous Recombination Deficiency in Pancreatic Acinar Cell Carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2023 Academic Article GET IT
Times cited: 35
Clonal hematopoiesis in survivors of childhood cancer. Blood advances. 2023 Academic Article GET IT
Times cited: 25
Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors. JCO precision oncology. 2023 Academic Article GET IT
Times cited: 18
The Impact of Germline Alterations in Appendiceal Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 5
Overcoming Barriers to Tumor Genomic Profiling through Direct-to-Patient Outreach. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Article GET IT
Times cited: 6
Unique Genomic Alterations and Microbial Profiles Identified in Patients With Gastric Cancer of African, European, and Asian Ancestry: A Novel Path for Precision Oncology. Annals of surgery. 2023 Academic Article GET IT
Times cited: 10
Comprehensive analysis of germline drivers in endometrial cancer. Journal of the National Cancer Institute. 2023 Academic Article GET IT
Times cited: 17
Germline drivers of gynecologic carcinosarcomas. Gynecologic oncology. 2023 Academic Article GET IT
Times cited: 11
Prevalence and Clinical Implications of Mismatch Repair-Proficient Colorectal Cancer in Patients With Lynch Syndrome. JCO precision oncology. 2023 Academic Article GET IT
Times cited: 14
Genomic mapping of metastatic organotropism in lung adenocarcinoma. Cancer cell. 2023 Academic Article GET IT
Times cited: 77
Dynamic Mutational Landscape of Cerebrospinal Fluid Circulating Tumor DNA and Predictors of Survival after Proton Craniospinal Irradiation for Leptomeningeal Metastases. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 15
Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers. Nature communications. 2023 Academic Article GET IT
Times cited: 78
Mutant-RB1 circulating tumor DNA in the blood of unilateral retinoblastoma patients: What happens during enucleation surgery: A pilot study. PloS one. 2023 Academic Article GET IT
Times cited: 9
High-Sensitivity Mutation Analysis of Cell-Free DNA for Disease Monitoring in Endometrial Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 48
NBN Pathogenic Germline Variants are Associated with Pan-Cancer Susceptibility and In Vitro DNA Damage Response Defects. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 19
Molecular Characterization of Acquired Resistance to KRASG12C-EGFR Inhibition in Colorectal Cancer. Cancer discovery. 2023 Academic Article GET IT
Times cited: 104
Genomic heterogeneity as a barrier to precision oncology in urothelial cancer. Cell reports. 2022 Academic Article GET IT
Times cited: 55
Germline-focused analysis of tumour-detected variants in 49,264 cancer patients: ESMO Precision Medicine Working Group recommendations. Annals of oncology : official journal of the European Society for Medical Oncology. 2022 Academic Article GET IT
Times cited: 107
Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Times cited: 41
Molecular Classification of Appendiceal Adenocarcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2022 Academic Article GET IT
Times cited: 51
Molecular Biomarkers of Disease Outcomes and Mechanisms of Acquired Resistance to First-Line Osimertinib in Advanced EGFR-Mutant Lung Cancers. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2022 Academic Article GET IT
Times cited: 92
Detectability of Plasma-Derived Circulating Tumor DNA Panel in Patients Undergoing Primary Treatment for Uveal Melanoma. Investigative ophthalmology & visual science. 2022 Academic Article GET IT
Times cited: 17
Reversion mutations in germline BRCA1/2-mutant tumors reveal a BRCA-mediated phenotype in non-canonical histologies. Nature communications. 2022 Academic Article GET IT
Times cited: 31
Overall survival with circulating tumor DNA-guided therapy in advanced non-small-cell lung cancer. Nature medicine. 2022 Academic Article GET IT
Times cited: 143
Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort. Cancer discovery. 2022 Academic Article GET IT
Times cited: 63
Bioinformatically Expanded Next-Generation Sequencing Analysis Optimizes Identification of Therapeutically Relevant MET Copy Number Alterations in >50,000 Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Times cited: 18
Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non-Muscle-Invasive Bladder Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Times cited: 13
Methylation Analyses Reveal Promoter Hypermethylation as a Rare Cause of "Second Hit" in Germline BRCA1-Associated Pancreatic Ductal Adenocarcinoma. Molecular diagnosis & therapy. 2022 Academic Article GET IT
Times cited: 9
Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors. Cancer cell. 2022 Academic Article GET IT
Times cited: 91
APOBEC mutagenesis, kataegis, chromothripsis in EGFR-mutant osimertinib-resistant lung adenocarcinomas. Annals of oncology : official journal of the European Society for Medical Oncology. 2022 Academic Article GET IT
Times cited: 43
Disparities in cancer genetics care by race/ethnicity among pan-cancer patients with pathogenic germline variants. Cancer. 2022 Academic Article GET IT
Times cited: 34
ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance. NPJ breast cancer. 2022 Academic Article GET IT
Times cited: 21
Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer. Nature medicine. 2022 Academic Article GET IT
Times cited: 114
Matched Molecular Profiling of Cell-Free DNA and Tumor Tissue in Patients With Advanced Clear Cell Renal Cell Carcinoma. JCO precision oncology. 2022 Academic Article GET IT
Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets. Nature communications. 2022 Academic Article GET IT
Times cited: 175
Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets. Science (New York, N.Y.). 2022 Academic Article GET IT
Times cited: 194
Author Correction: The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers. Nature communications. 2022 Article GET IT
Times cited: 2
The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers. Nature communications. 2022 Academic Article GET IT
Times cited: 100
Phase II Trial of Imatinib Plus Binimetinib in Patients With Treatment-Naive Advanced Gastrointestinal Stromal Tumor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2022 Academic Article GET IT
Times cited: 30
Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights. Nature communications. 2021 Academic Article GET IT
Times cited: 42
Diverse alterations associated with resistance to KRAS(G12C) inhibition. Nature. 2021 Academic Article GET IT
Times cited: 345
The context-specific role of germline pathogenicity in tumorigenesis. Nature genetics. 2021 Academic Article GET IT
Times cited: 88
Improved prediction of immune checkpoint blockade efficacy across multiple cancer types. Nature biotechnology. 2021 Academic Article GET IT
Times cited: 218
Clonal hematopoiesis is associated with risk of severe Covid-19. Nature communications. 2021 Academic Article GET IT
Times cited: 105
A quick guide for clinical oncology. Nature cancer. 2021 Article GET IT
Times cited: 1
Recurrence biomarkers of triple negative breast cancer treated with neoadjuvant chemotherapy and anti-EGFR antibodies. NPJ breast cancer. 2021 Academic Article GET IT
Times cited: 13
RB1 Circulating Tumor DNA in the Blood of Patients with Unilateral Retinoblastoma: Before and after Intra-arterial Chemotherapy. Ophthalmology science. 2021 Academic Article GET IT
Times cited: 16
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS. Nature communications. 2021 Academic Article GET IT
Times cited: 136
Therapeutic Implications of Germline Testing in Patients With Advanced Cancers. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2021 Academic Article GET IT
Times cited: 123
Retrospective Evaluation of Somatic Alterations in Cell-Free DNA from Blood in Retinoblastoma. Ophthalmology science. 2021 Academic Article GET IT
Times cited: 30
Prevalence and Characterization of Biallelic and Monoallelic NTHL1 and MSH3 Variant Carriers From a Pan-Cancer Patient Population. JCO precision oncology. 2021 Academic Article GET IT
Times cited: 17
Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors. Nature cancer. 2021 Academic Article GET IT
Times cited: 137
OncoTree: A Cancer Classification System for Precision Oncology. JCO clinical cancer informatics. 2021 Academic Article GET IT
Times cited: 114
Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis. Nature communications. 2021 Academic Article GET IT
Times cited: 88
Alterations in PTEN and ESR1 promote clinical resistance to alpelisib plus aromatase inhibitors. Nature cancer. 2020 Academic Article GET IT
Times cited: 136
Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle. Annals of oncology : official journal of the European Society for Medical Oncology. 2018 Article GET IT
Times cited: 20
Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2). Science signaling. 2018 Academic Article GET IT
Times cited: 66
Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy. Science (New York, N.Y.). 2017 Academic Article GET IT
Times cited: 932
Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. Nature medicine. 2017 Article GET IT
Times cited: 52

VIVO Weill Cornell Medical College

Michael Berger Assistant Professor of Pathology and Laboratory Medicine

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selected publications

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