Berger, Michael

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Multiomic profiling identifies predictors of survival in African American patients with acute myeloid leukemia. Nature genetics. 2024 Academic Article GET IT
Real-world experience with circulating tumor DNA in cerebrospinal fluid from patients with central nervous system tumors. Acta neuropathologica communications. 2024 Academic Article GET IT
Tumor suppressor heterozygosity and homologous recombination deficiency mediate resistance to front-line therapy in breast cancer. 2024 GET IT
Tracking clonal evolution of drug resistance in ovarian cancer patients by exploiting structural variants in cfDNA. 2024 GET IT
DNA liquid biopsy-based prediction of cancer-associated venous thromboembolism. Nature medicine. 2024 Academic Article GET IT
Maximizing the clinical utility and performance of cytology samples for comprehensive genetic profiling - A report on the impact of process optimization through the analysis of 4,871 cytology samples profiled by MSK-IMPACT. 2024 GET IT
Precision oncology: current and future platforms for treatment selection. Trends in cancer. 2024 Review GET IT
Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2024 Academic Article GET IT
Clinicogenomic predictors of outcomes in patients with hepatocellular carcinoma treated with immunotherapy. The oncologist. 2024 Academic Article GET IT
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment. Nature medicine. 2024 Academic Article GET IT
Genomic Landscape of Adenocarcinomas Across the Gastroesophageal Junction: Moving on from the Siewert Classification. Annals of surgery. 2024 Academic Article GET IT
Serial Cell-Free DNA Sequencing in ROS1 Fusion-Positive Lung Cancers During Treatment With Entrectinib. JCO precision oncology. 2024 Academic Article GET IT
Early on-treatment assessment of T-cells, cytokines and tumor DNA with adaptively-dosed nivolumab + ipilimumab: final results from the phase 2 ADAPT-IT study. Clinical cancer research : an official journal of the American Association for Cancer Research. 2024 Academic Article GET IT
Natural History and Genomic Landscape of Chemotherapy-Resistant Muscle-Invasive Bladder Cancer. JCO precision oncology. 2024 Academic Article GET IT
Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies. Haematologica. 2024 Academic Article GET IT
Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data. Cancer discovery. 2024 Academic Article GET IT
Convergent evolution of BRCA2 reversion mutations under therapeutic pressure by PARP inhibition and platinum chemotherapy. NPJ precision oncology. 2024 Academic Article GET IT
Clinical utility of plasma cell-free DNA in pancreatic neuroendocrine neoplasms. Endocrine-related cancer. 2024 Academic Article GET IT
High risk and silent clonal hematopoietic genotypes in patients with non-hematologic cancer. Blood advances. 2024 Academic Article GET IT
Standard-of-care systemic therapy with or without stereotactic body radiotherapy in patients with oligoprogressive breast cancer or non-small-cell lung cancer (Consolidative Use of Radiotherapy to Block [CURB] oligoprogression): an open-label, randomised, controlled, phase 2 study. Lancet (London, England). 2023 Academic Article GET IT
Pathogenic germline variants in non-BRCA1/2 homologous recombination genes in ovarian cancer: Analysis of tumor phenotype and survival. Gynecologic oncology. 2023 Academic Article GET IT
Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing. Nature communications. 2023 Academic Article GET IT
Pathogenic germline variants in patients with endometrial cancer of diverse ancestry. Cancer. 2023 Academic Article GET IT
Times cited: 1
Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers. Cancer cell. 2023 Academic Article GET IT
Genomic ancestry in kidney cancer: Correlations with clinical and molecular features. Cancer. 2023 Academic Article GET IT
Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer. Cancer discovery. 2023 Academic Article GET IT
Neoplasia risk in patients with Lynch syndrome treated with immune checkpoint blockade. Nature medicine. 2023 Academic Article GET IT
Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data. 2023 GET IT
Clinical and genomic landscape of FGFR3-altered urothelial carcinoma and treatment outcomes with erdafitinib: a real-world experience. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
First-line regorafenib with nivolumab and chemotherapy in advanced oesophageal, gastric, or gastro-oesophageal junction cancer in the USA: a single-arm, single-centre, phase 2 trial. The Lancet. Oncology. 2023 Academic Article GET IT
Germline Pathogenic Variants and Genetic Counseling by Ancestry in Patients With Epithelial Ovarian Cancer. JCO precision oncology. 2023 Academic Article GET IT
Targeted Molecular Profiling of Circulating Cell-Free DNA in Patients With Advanced Hepatocellular Carcinoma. JCO precision oncology. 2023 Academic Article GET IT
Molecular characterization of endometrial carcinomas in Black and White patients reveals disparate drivers with therapeutic implications. Cancer discovery. 2023 Academic Article GET IT
Assessing the Genomic Landscape of Cervical Cancers: Clinical Opportunities and Therapeutic Targets. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Genomic Profiling Reveals Germline Predisposition and Homologous Recombination Deficien cy in Pancreatic Acinar Cell Carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2023 Academic Article GET IT
Clonal hematopoiesis in survivors of childhood cancer. Blood advances. 2023 Academic Article GET IT
Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors. JCO precision oncology. 2023 Academic Article GET IT
The Impact of Germline Alterations in Appendiceal Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Overcoming Barriers to Tumor Genomic Profiling through Direct-to-Patient Outreach. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Comment GET IT
Times cited: 2
Unique Genomic Alterations and Microbial Profiles Identified in Patients With Gastric Cancer of African, European, and Asian Ancestry: A Novel Path for Precision Oncology. Annals of surgery. 2023 Academic Article GET IT
Comprehensive analysis of germline drivers in endometrial cancer. Journal of the National Cancer Institute. 2023 Academic Article GET IT
Germline drivers of gynecologic carcinosarcomas. Gynecologic oncology. 2023 Academic Article GET IT
Prevalence and Clinical Implications of Mismatch Repair-Proficient Colorectal Cancer in Patients With Lynch Syndrome. JCO precision oncology. 2023 Academic Article GET IT
Genomic mapping of metastatic organotropism in lung adenocarcinoma. Cancer cell. 2023 Academic Article GET IT
Inferring genetic ancestry from cancer sequencing data. Trends in genetics : TIG. 2023 Academic Article GET IT
Loss of CDKN2A/B is a Molecular Marker of High-grade Histology and is Associated with Aggressive Behavior in Acinic Cell Carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2023 Academic Article GET IT
Dynamic Mutational Landscape of Cerebrospinal Fluid Circulating Tumor DNA and Predictors of Survival after Proton Craniospinal Irradiation for Leptomeningeal Metastases. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 5
Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers. Nature communications. 2023 Academic Article GET IT
Times cited: 33
Mutant-RB1 circulating tumor DNA in the blood of unilateral retinoblastoma patients: What happens during enucleation surgery: A pilot study. PloS one. 2023 Academic Article GET IT
High-Sensitivity Mutation Analysis of Cell-Free DNA for Disease Monitoring in Endometrial Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 16
NBN Pathogenic Germline Variants are Associated with Pan-Cancer Susceptibility and In Vitro DNA Damage Response Defects. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 6
Molecular Characterization of Acquired Resistance to KRASG12C-EGFR Inhibition in Colorectal Cancer. Cancer discovery. 2023 Academic Article GET IT
Times cited: 41
Genomic heterogeneity as a barrier to precision oncology in urothelial cancer. Cell reports. 2022 Academic Article GET IT
Times cited: 17
Germline-focused analysis of tumour-detected variants in 49,264 cancer patients: ESMO Precision Medicine Working Group recommendations. Annals of oncology : official journal of the European Society for Medical Oncology. 2022 Academic Article GET IT
Times cited: 6
Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Times cited: 6
Molecular Classification of Appendiceal Adenocarcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2022 Academic Article GET IT
Times cited: 18
Molecular Biomarkers of Disease Outcomes and Mechanisms of Acquired Resistance to First-Line Osimertinib in Advanced EGFR-Mutant Lung Cancers. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2022 Academic Article GET IT
Times cited: 42
Detectability of Plasma-Derived Circulating Tumor DNA Panel in Patients Undergoing Primary Treatment for Uveal Melanoma. Investigative ophthalmology & visual science. 2022 Academic Article GET IT
Times cited: 6
Reversion mutations in germline BRCA1/2-mutant tumors reveal a BRCA-mediated phenotype in non-canonical histologies. Nature communications. 2022 Academic Article GET IT
Times cited: 15
Overall survival with circulating tumor DNA-guided therapy in advanced non-small-cell lung cancer. Nature medicine. 2022 Academic Article GET IT
Times cited: 64
Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort. Cancer discovery. 2022 Academic Article GET IT
Bioinformatically Expanded Next-Generation Sequencing Analysis Optimizes Identification of Therapeutically Relevant MET Copy Number Alterations in >50,000 Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Methylation Analyses Reveal Promoter Hypermethylation as a Rare Cause of "Second Hit" in Germline BRCA1-Associated Pancreatic Ductal Adenocarcinoma. Molecular diagnosis & therapy. 2022 Academic Article GET IT
Times cited: 3
Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors. Cancer cell. 2022 Academic Article GET IT
Times cited: 54
APOBEC mutagenesis, kataegis, chromothripsis in EGFR-mutant osimertinib-resistant lung adenocarcinomas. Annals of oncology : official journal of the European Society for Medical Oncology. 2022 Academic Article GET IT
Times cited: 25
Disparities in cancer genetics care by race/ethnicity among pan-cancer patients with pathogenic germline variants. Cancer. 2022 Academic Article GET IT
ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance. NPJ breast cancer. 2022 Academic Article GET IT
Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer. Nature medicine. 2022 Academic Article GET IT
Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non-Muscle-Invasive Bladder Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Matched Molecular Profiling of Cell-Free DNA and Tumor Tissue in Patients With Advanced Clear Cell Renal Cell Carcinoma. JCO precision oncology. 2022 Academic Article GET IT
Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets. Nature communications. 2022 Academic Article GET IT
The Role of the TP53 Pathway in Predicting Response to Neoadjuvant Therapy in Esophageal Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets. Science (New York, N.Y.). 2022 Academic Article GET IT
Germline Pathogenic Variants Impact Clinicopathology of Advanced Lung Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2022 Academic Article GET IT
Evaluation of TERT mRNA expression using RNAscope®: A potential histopathologic diagnostic and prognostic tool. Pathology, research and practice. 2022 Academic Article GET IT
Defining Novel DNA Virus-Tumor Associations and Genomic Correlates Using Prospective Clinical Tumor/Normal Matched Sequencing Data. The Journal of molecular diagnostics : JMD. 2022 Academic Article GET IT
The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers. Nature communications. 2022 Academic Article GET IT
Next-generation Sequencing of Cerebrospinal Fluid for Clinical Molecular Diagnostics in Pediatric, Adolescent and Young Adult (AYA) Brain Tumor Patients. Neuro-oncology. 2022 Academic Article GET IT
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients. Cell. 2022 Academic Article GET IT
Phase Ib Trial of the Combination of Imatinib and Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumors (GIST). Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Cancer Causative Mutations Occurring in Early Embryogenesis. Cancer discovery. 2021 Academic Article GET IT
Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights. Nature communications. 2021 Academic Article GET IT
Diverse alterations associated with resistance to KRAS(G12C) inhibition. Nature. 2021 Academic Article GET IT
Times cited: 202
The context-specific role of germline pathogenicity in tumorigenesis. Nature genetics. 2021 Academic Article GET IT
Times cited: 5
Improved prediction of immune checkpoint blockade efficacy across multiple cancer types. Nature biotechnology. 2021 Academic Article GET IT
Times cited: 3
Clonal hematopoiesis is associated with risk of severe Covid-19. Nature communications. 2021 Academic Article GET IT
Times cited: 77
A quick guide for clinical oncology. Nature cancer. 2021 Comment GET IT
TERT Copy Number Alterations, Promoter Mutations and Rearrangements in Adrenocortical Carcinomas. Endocrine pathology. 2021 Academic Article GET IT
Recurrence biomarkers of triple negative breast cancer treated with neoadjuvant chemotherapy and anti-EGFR antibodies. NPJ breast cancer. 2021 Academic Article GET IT
A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers. Journal of the National Cancer Institute. 2021 Academic Article GET IT
Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes. Cancer. 2021 Academic Article GET IT
Clinical utility of next-generation sequencing-based ctDNA testing for common and novel ALK fusions. Lung cancer (Amsterdam, Netherlands). 2021 Academic Article GET IT
Times cited: 18
RB1 Circulating Tumor DNA in the Blood of Patients with Unilateral Retinoblastoma: Before and after Intra-arterial Chemotherapy. Ophthalmology science. 2021 Academic Article GET IT
Times cited: 8
Resource-efficient pooled sequencing expands translational impact in solid tumors. Kidney cancer journal : official journal of the Kidney Cancer Association. 2021 Academic Article GET IT
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS. Nature communications. 2021 Academic Article GET IT
Times cited: 87
Therapeutic Implications of Germline Testing in Patients With Advanced Cancers. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2021 Academic Article GET IT
Times cited: 81
Tumor fraction-guided cell-free DNA profiling in metastatic solid tumor patients. Genome medicine. 2021 Academic Article GET IT
Times cited: 26
Response Rates to Anti-PD-1 Immunotherapy in Microsatellite-Stable Solid Tumors With 10 or More Mutations per Megabase. JAMA oncology. 2021 Academic Article GET IT
Times cited: 137
Respiratory complex and tissue lineage drive recurrent mutations in tumour mtDNA. Nature metabolism. 2021 Academic Article GET IT
Times cited: 12
Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways. Clinical cancer research : an official journal of the American Association for Cancer Research. 2021 Academic Article GET IT
Times cited: 9
Clinical Experience of Cerebrospinal Fluid-Based Liquid Biopsy Demonstrates Superiority of Cell-Free DNA over Cell Pellet Genomic DNA for Molecular Profiling. The Journal of molecular diagnostics : JMD. 2021 Academic Article GET IT
Times cited: 23
Retrospective Evaluation of Somatic Alterations in Cell-Free DNA from Blood in Retinoblastoma. Ophthalmology science. 2021 Academic Article GET IT
Times cited: 19
Prevalence and Characterization of Biallelic and Monoallelic NTHL1 and MSH3 Variant Carriers From a Pan-Cancer Patient Population. JCO precision oncology. 2021 Academic Article GET IT
Times cited: 11
Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors. Nature cancer. 2021 Academic Article GET IT
Times cited: 95
A Genomic-Pathologic Annotated Risk Model to Predict Recurrence in Early-Stage Lung Adenocarcinoma. JAMA surgery. 2021 Academic Article GET IT
Times cited: 60
OncoTree: A Cancer Classification System for Precision Oncology. JCO clinical cancer informatics. 2021 Academic Article GET IT
Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors. Nature communications. 2021 Academic Article GET IT
Times cited: 243
Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis. Nature communications. 2021 Academic Article GET IT
Times cited: 67
Utility of Serial cfDNA NGS for Prospective Genomic Analysis of Patients on a Phase I Basket Study. JCO precision oncology. 2021 Academic Article GET IT
Times cited: 5
Molecular Changes in Retinoblastoma beyond RB1: Findings from Next-Generation Sequencing. Cancers. 2021 Academic Article GET IT
Times cited: 34
The association between tumor mutational burden and prognosis is dependent on treatment context. Nature genetics. 2021 Academic Article GET IT
Times cited: 151
A Pan-Cancer Study of Somatic TERT Promoter Mutations and Amplification in 30,773 Tumors Profiled by Clinical Genomic Sequencing. The Journal of molecular diagnostics : JMD. 2020 Academic Article GET IT
Times cited: 22
Characterization and Clinical Outcomes of DNA Mismatch Repair-deficient Small Bowel Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Times cited: 24
Germ Cell Tumor Molecular Heterogeneity Revealed Through Analysis of Primary and Metastasis Pairs. JCO precision oncology. 2020 Academic Article GET IT
Times cited: 10
Cancer therapy shapes the fitness landscape of clonal hematopoiesis. Nature genetics. 2020 Academic Article GET IT
Times cited: 379
TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors. Cancer discovery. 2020 Academic Article GET IT
Times cited: 39
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. Cell. 2020 Academic Article GET IT
Times cited: 740
A phase 2 trial of buparlisib in patients with platinum-resistant metastatic urothelial carcinoma. Cancer. 2020 Academic Article GET IT
Times cited: 23
Molecular profiling and analysis of genetic aberrations aimed at identifying potential therapeutic targets in fibrolamellar carcinoma of the liver. Cancer. 2020 Academic Article GET IT
Cell-free DNA profiling in retinoblastoma patients with advanced intraocular disease: An MSKCC experience. Cancer medicine. 2020 Academic Article GET IT
Times cited: 36
Developing Quality Programs for Cell-Free DNA (cfDNA) Extraction from Peripheral Blood. The journal of applied laboratory medicine. 2020 Academic Article GET IT
Effect of Osimertinib and Bevacizumab on Progression-Free Survival for Patients With Metastatic EGFR-Mutant Lung Cancers: A Phase 1/2 Single-Group Open-Label Trial. JAMA oncology. 2020 Academic Article GET IT
Times cited: 106
Alterations in driver genes are predictive of survival in patients with resected pancreatic ductal adenocarcinoma. Cancer. 2020 Academic Article GET IT
Times cited: 48
Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Times cited: 138
Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature communications. 2020 Academic Article GET IT
Times cited: 29
Fragment Size Analysis May Distinguish Clonal Hematopoiesis from Tumor-Derived Mutations in Cell-Free DNA. Clinical chemistry. 2020 Article GET IT
Times cited: 32
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers. Cancer discovery. 2020 Academic Article GET IT
Times cited: 172
Alterations in PTEN and ESR1 promote clinical resistance to alpelisib plus aromatase inhibitors. Nature cancer. 2020 Academic Article GET IT
Times cited: 99
Germline alterations in patients with biliary tract cancers: A spectrum of significant and previously underappreciated findings. Cancer. 2020 Academic Article GET IT
Times cited: 33
The Clinical Management of Clonal Hematopoiesis: Creation of a Clonal Hematopoiesis Clinic. Hematology/oncology clinics of North America. 2020 Information Resource GET IT
Times cited: 11
Author Correction: Tumour lineage shapes BRCA-mediated phenotypes. 2020 GET IT
Development of Genome-Derived Tumor Type Prediction to Inform Clinical Cancer Care. JAMA oncology. 2020 Academic Article GET IT
Times cited: 77
Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms. Nature medicine. 2019 Academic Article GET IT
Times cited: 137
Coaltered Ras/B-raf and TP53 Is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Patients with Metastatic Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 59
PD-1 Blockade in Advanced Adrenocortical Carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2019 Academic Article GET IT
Times cited: 130
Genomic Characterization of ERBB2-Driven Biliary Cancer and a Case of Response to Ado-Trastuzumab Emtansine. JCO precision oncology. 2019 Academic Article GET IT
Times cited: 31
Genomic Profiling Identifies Association of IDH1/IDH2 Mutation with Longer Relapse-Free and Metastasis-Free Survival in High-Grade Chondrosarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 60
A rectal cancer organoid platform to study individual responses to chemoradiation. Nature medicine. 2019 Academic Article GET IT
Times cited: 338
Genomic and Transcriptomic Characterization of Papillary Microcarcinomas With Lateral Neck Lymph Node Metastases. The Journal of clinical endocrinology and metabolism. 2019 Academic Article GET IT
Times cited: 26
Regorafenib in Combination with First-Line Chemotherapy for Metastatic Esophagogastric Cancer. The oncologist. 2019 Academic Article GET IT
Times cited: 11
PIK3CA and MAP3K1 alterations imply luminal A status and are associated with clinical benefit from pan-PI3K inhibitor buparlisib and letrozole in ER+ metastatic breast cancer. NPJ breast cancer. 2019 Academic Article GET IT
Times cited: 29
Fumarate hydratase FH c.1431_1433dupAAA (p.Lys477dup) variant is not associated with cancer including renal cell carcinoma. Human mutation. 2019 Academic Article GET IT
Times cited: 27
Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 30
Resistance to TRK inhibition mediated by convergent MAPK pathway activation. Nature medicine. 2019 Academic Article GET IT
Times cited: 158
Germline-focussed analysis of tumour-only sequencing: recommendations from the ESMO Precision Medicine Working Group. Annals of oncology : official journal of the European Society for Medical Oncology. 2019 Academic Article GET IT
Times cited: 150
Real-World Outcomes of an Automated Physician Support System for Genome-Driven Oncology. JCO precision oncology. 2019 Academic Article GET IT
Clinical and Molecular Predictors of Response to Immune Checkpoint Inhibitors in Patients with Advanced Esophagogastric Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 80
Tumour lineage shapes BRCA-mediated phenotypes. Nature. 2019 Academic Article GET IT
Times cited: 288
Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 107
DNA methylation-based classification of sinonasal undifferentiated carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2019 Academic Article GET IT
Times cited: 91
Rare BRAF mutations in pancreatic neuroendocrine tumors may predict response to RAF and MEK inhibition. PloS one. 2019 Academic Article GET IT
Times cited: 13
Massively parallel sequencing analysis of benign melanocytic naevi. Histopathology. 2019 Academic Article GET IT
Times cited: 11
High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 313
Understanding inherited risk in unselected newly diagnosed patients with endometrial cancer. JCO precision oncology. 2019 Academic Article GET IT
Times cited: 14
Genomic landscape of inverted urothelial papilloma and urothelial papilloma of the bladder. The Journal of pathology. 2019 Academic Article GET IT
Times cited: 36
JAK2/PD-L1/PD-L2 (9p24.1) amplifications in renal cell carcinomas with sarcomatoid transformation: implications for clinical management. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2019 Academic Article GET IT
Times cited: 50
Efficacy of Combined VEGFR1-3, PDGFα/β, and FGFR1-3 Blockade Using Nintedanib for Esophagogastric Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 13
Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade. JAMA oncology. 2019 Academic Article GET IT
Times cited: 456
The repertoire of genetic alterations in salivary duct carcinoma including a novel HNRNPH3-ALK rearrangement. Human pathology. 2019 Academic Article GET IT
Times cited: 37
Harnessing Clinical Sequencing Data for Survival Stratification of Patients with Metastatic Lung Adenocarcinomas. JCO precision oncology. 2019 Academic Article GET IT
Times cited: 30
Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid. Nature. 2019 Academic Article GET IT
Times cited: 378
Ampullary cancer: Evaluation of somatic and germline genetic alterations and association with clinical outcomes. Cancer. 2019 Academic Article GET IT
Times cited: 33
Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma. Blood. 2018 Academic Article GET IT
Times cited: 178
Binimetinib plus Gemcitabine and Cisplatin Phase I/II Trial in Patients with Advanced Biliary Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 25
Next-Generation Sequencing-Based Assessment of JAK2, PD-L1, and PD-L2 Copy Number Alterations at 9p24.1 in Breast Cancer: Potential Implications for Clinical Management. The Journal of molecular diagnostics : JMD. 2018 Academic Article GET IT
Times cited: 20
EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer. Cancer discovery. 2018 Academic Article GET IT
Times cited: 122
Radioactive Iodine-Related Clonal Hematopoiesis in Thyroid Cancer Is Common and Associated With Decreased Survival. The Journal of clinical endocrinology and metabolism. 2018 Academic Article GET IT
Times cited: 31
Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer. Cancer cell. 2018 Academic Article GET IT
Times cited: 66
Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2018 Academic Article GET IT
Times cited: 405
Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 394
Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 170
Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2). Science signaling. 2018 Academic Article GET IT
Times cited: 58
Genomic Differences Between "Primary" and "Secondary" Muscle-invasive Bladder Cancer as a Basis for Disparate Outcomes to Cisplatin-based Neoadjuvant Chemotherapy. European urology. 2018 Academic Article GET IT
Times cited: 114
Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms. Journal of the National Cancer Institute. 2018 Academic Article GET IT
Times cited: 180
The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers. Cancer cell. 2018 Academic Article GET IT
Times cited: 636
Immunohistochemical analysis of estrogen receptor in breast cancer with ESR1 mutations detected by hybrid capture-based next-generation sequencing. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2018 Academic Article GET IT
Times cited: 15
Phase II study of trastuzumab with modified docetaxel, cisplatin, and 5 fluorouracil in metastatic HER2-positive gastric cancer. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2018 Academic Article GET IT
Times cited: 14
Clinical Utility of Prospective Molecular Characterization in Advanced Endometrial Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 100
Genome doubling shapes the evolution and prognosis of advanced cancers. Nature genetics. 2018 Academic Article GET IT
Times cited: 367
The emerging clinical relevance of genomics in cancer medicine. Nature reviews. Clinical oncology. 2018 Information Resource GET IT
Times cited: 356
Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 377
KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function. Oncogene. 2018 Academic Article GET IT
Times cited: 95
Multicenter Prospective Phase II Trial of Neoadjuvant Dose-Dense Gemcitabine Plus Cisplatin in Patients With Muscle-Invasive Bladder Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2018 Academic Article GET IT
Times cited: 110
Rates of TP53 Mutation are Significantly Elevated in African American Patients with Gastric Cancer. Annals of surgical oncology. 2018 Academic Article GET IT
Times cited: 20
Real-Time Genomic Characterization of Metastatic Pancreatic Neuroendocrine Tumors Has Prognostic Implications and Identifies Potential Germline Actionability. JCO precision oncology. 2018 Academic Article GET IT
Times cited: 55
Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 204
The value of cell-free DNA for molecular pathology. The Journal of pathology. 2018 Information Resource GET IT
Times cited: 93
Alterations in DNA Damage Response and Repair Genes as Potential Marker of Clinical Benefit From PD-1/PD-L1 Blockade in Advanced Urothelial Cancers. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2018 Academic Article GET IT
Times cited: 400
HER kinase inhibition in patients with HER2- and HER3-mutant cancers. Nature. 2018 Academic Article GET IT
Times cited: 588
Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2018 Academic Article GET IT
Times cited: 1060
Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer. Cancer cell. 2018 Academic Article GET IT
Times cited: 560
Accelerating Discovery of Functional Mutant Alleles in Cancer. Cancer discovery. 2017 Academic Article GET IT
Times cited: 249
Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy. Science (New York, N.Y.). 2017 Academic Article GET IT
Times cited: 777
Clinical and molecular characterization of patients with cancer of unknown primary in the modern era. Annals of oncology : official journal of the European Society for Medical Oncology. 2017 Academic Article GET IT
Times cited: 82
Small-Cell Carcinomas of the Bladder and Lung Are Characterized by a Convergent but Distinct Pathogenesis. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Academic Article GET IT
Times cited: 87
Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer. Cancer discovery. 2017 Academic Article GET IT
Times cited: 285
Effects of Co-occurring Genomic Alterations on Outcomes in Patients with KRAS-Mutant Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Academic Article GET IT
Times cited: 320
Reliable Pan-Cancer Microsatellite Instability Assessment by Using Targeted Next-Generation Sequencing Data. JCO precision oncology. 2017 Academic Article GET IT
Times cited: 269
Universal screening for microsatellite instability in colorectal cancer in the clinical genomics era: new recommendations, methods, and considerations. Familial cancer. 2017 Article GET IT
Times cited: 12
Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition. Cancer research. 2017 Academic Article GET IT
Times cited: 66
Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing. JAMA. 2017 Academic Article GET IT
Times cited: 362
The genetic landscape of endometrial clear cell carcinomas. The Journal of pathology. 2017 Academic Article GET IT
Times cited: 181
Oncologist use and perception of large panel next-generation tumor sequencing. Annals of oncology : official journal of the European Society for Medical Oncology. 2017 Academic Article GET IT
Times cited: 32
Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations. Blood. 2017 Academic Article GET IT
Times cited: 84
Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes. Cell stem cell. 2017 Academic Article GET IT
Times cited: 563
Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. 2017 GET IT
Times cited: 23
Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2017 Academic Article GET IT
Times cited: 32
Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Academic Article GET IT
Times cited: 80
An approach to suppress the evolution of resistance in BRAF^V600E-mutant cancer. Nature medicine. 2017 Academic Article GET IT
Times cited: 125
Local recurrences at the anastomotic area are clonally related to the primary tumor in sporadic colorectal carcinoma. Oncotarget. 2017 Academic Article GET IT
Times cited: 10
PTEN Loss-of-Function Alterations Are Associated With Intrinsic Resistance to BRAF Inhibitors in Metastatic Melanoma. JCO precision oncology. 2017 Academic Article GET IT
Times cited: 40
Genomic Alterations in Fatal Forms of Non-Anaplastic Thyroid Cancer: Identification of MED12 and RBM10 as Novel Thyroid Cancer Genes Associated with Tumor Virulence. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Academic Article GET IT
Times cited: 90
A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Academic Article GET IT
Times cited: 112
Frequent IDH2 R172 mutations in undifferentiated and poorly-differentiated sinonasal carcinomas. The Journal of pathology. 2017 Academic Article GET IT
Times cited: 88
A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors. Cancer discovery. 2017 Academic Article GET IT
Times cited: 339
Next-generation Sequencing of Nonmuscle Invasive Bladder Cancer Reveals Potential Biomarkers and Rational Therapeutic Targets. European urology. 2017 Academic Article GET IT
Times cited: 263
Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML. Blood. 2017 Academic Article GET IT
Times cited: 68
Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making. JCO precision oncology. 2017 Academic Article GET IT
Times cited: 409
Plasma DNA-based molecular diagnosis, prognostication, and monitoring of patients with EWSR1 fusion-positive sarcomas. JCO precision oncology. 2017 Academic Article GET IT
Times cited: 47
Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing. BMC medical genomics. 2017 Academic Article GET IT
Times cited: 106
OncoKB: A Precision Oncology Knowledge Base. JCO precision oncology. 2017 Academic Article GET IT
Times cited: 1655
AKT Inhibition in Solid Tumors With AKT1 Mutations. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2017 Academic Article GET IT
Times cited: 230
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. Nature medicine. 2017 Academic Article GET IT
Times cited: 2338
Next-generation sequencing of urine specimens: A novel platform for genomic analysis in patients with non-muscle-invasive urothelial carcinoma treated with bacille Calmette-Guérin. Cancer cytopathology. 2017 Academic Article GET IT
Times cited: 27
Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies. Cancer discovery. 2017 Academic Article GET IT
Times cited: 490
Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high-grade serous ovarian and breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology. 2017 Academic Article GET IT
Times cited: 171
Precision oncology: Charting a path forward to broader deployment of genomic profiling. PLoS medicine. 2017 Academic Article GET IT
Times cited: 15
Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival. Molecular cancer research : MCR. 2017 Academic Article GET IT
Times cited: 22
The Molecular Landscape of Recurrent and Metastatic Head and Neck Cancers: Insights From a Precision Oncology Sequencing Platform. JAMA oncology. 2017 Academic Article GET IT
Times cited: 182
DNA Damage Response and Repair Gene Alterations Are Associated with Improved Survival in Patients with Platinum-Treated Advanced Urothelial Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Academic Article GET IT
Times cited: 219
Next-Generation Assessment of Human Epidermal Growth Factor Receptor 2 (ERBB2) Amplification Status: Clinical Validation in the Context of a Hybrid Capture-Based, Comprehensive Solid Tumor Genomic Profiling Assay. The Journal of molecular diagnostics : JMD. 2016 Academic Article GET IT
Times cited: 94
Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology-molecular associations: clinical and biological implications. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2016 Academic Article GET IT
Times cited: 70
Clinical and genetic determinants of ovarian metastases from colorectal cancer. Cancer. 2016 Academic Article GET IT
Times cited: 51
Phase II Trial and Correlative Genomic Analysis of Everolimus Plus Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 67
Delivering on the promise of precision cancer medicine. Genome medicine. 2016 Editorial Article GET IT
Times cited: 8
Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma. European urology. 2016 Academic Article GET IT
Times cited: 166
Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Nature communications. 2016 Academic Article GET IT
Times cited: 144
Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 141
Genomic characterization of response to chemoradiation in urothelial bladder cancer. Cancer. 2016 Academic Article GET IT
Times cited: 52
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer. The New England journal of medicine. 2016 Academic Article GET IT
Times cited: 1220
Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor. Nature. 2016 Academic Article GET IT
Times cited: 349
Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 295
Genomic aberrations frequently alter chromatin regulatory genes in chordoma. Genes, chromosomes & cancer. 2016 Academic Article GET IT
Times cited: 55
A Phase Ib Study of Alpelisib (BYL719), a PI3Kα-Specific Inhibitor, with Letrozole in ER+/HER2- Metastatic Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Academic Article GET IT
Times cited: 251
A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung cancer. Lung cancer (Amsterdam, Netherlands). 2016 Academic Article GET IT
Times cited: 55
Comprehensive Molecular Characterization of Salivary Duct Carcinoma Reveals Actionable Targets and Similarity to Apocrine Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Academic Article GET IT
Times cited: 151
Integrating Genomics Into Clinical Pediatric Oncology Using the Molecular Tumor Board at the Memorial Sloan Kettering Cancer Center. Pediatric blood & cancer. 2016 Academic Article GET IT
Times cited: 32
Somatic PIK3CA mutations as a driver of sporadic venous malformations. Science translational medicine. 2016 Academic Article GET IT
Times cited: 133
KRAS and Combined KRAS/TP53 Mutations in Locally Advanced Rectal Cancer are Independently Associated with Decreased Response to Neoadjuvant Therapy. Annals of surgical oncology. 2016 Academic Article GET IT
Times cited: 75
Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 190
Genetic analysis of five children with essential thrombocytosis identified mutations in cancer-associated genes with roles in transcriptional regulation. Haematologica. 2016 Article GET IT
Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Academic Article GET IT
Times cited: 356
Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphology. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2016 Academic Article GET IT
Times cited: 91
Frequent somatic CDH1 loss-of-function mutations in plasmacytoid variant bladder cancer. Nature genetics. 2016 Academic Article GET IT
Times cited: 142
Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers. The Journal of clinical investigation. 2016 Academic Article GET IT
Times cited: 856
Investigation of Somatic GNAQ, GNA11, BAP1 and SF3B1 Mutations in Ophthalmic Melanocytomas. Ocular oncology and pathology. 2016 Academic Article GET IT
Times cited: 12
Genomic Biomarkers for the Prediction of Stage and Prognosis of Upper Tract Urothelial Carcinoma. The Journal of urology. 2016 Academic Article GET IT
Times cited: 38
Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA. Nucleic acids research. 2015 Academic Article GET IT
Times cited: 30
Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma. Nature communications. 2015 Academic Article GET IT
Times cited: 608
Targeted exome sequencing profiles genetic alterations in leiomyosarcoma. Genes, chromosomes & cancer. 2015 Academic Article GET IT
Times cited: 37
Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway. Oncotarget. 2015 Academic Article GET IT
Times cited: 105
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer. Nature. 2015 Academic Article GET IT
Times cited: 186
NF1 Mutations Are Common in Desmoplastic Melanoma. The American journal of surgical pathology. 2015 Academic Article GET IT
Times cited: 89
Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia. The New England journal of medicine. 2015 Academic Article GET IT
Times cited: 269
ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma. Oncotarget. 2015 Academic Article GET IT
Times cited: 11
Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials. Drug discovery today. 2015 Article GET IT
Times cited: 126
Genomic Characterization of Upper Tract Urothelial Carcinoma. European urology. 2015 Academic Article GET IT
Times cited: 198
Phase II Trial of Sorafenib in Patients with Chemotherapy Refractory Metastatic Esophageal and Gastroesophageal (GE) Junction Cancer. PloS one. 2015 Academic Article GET IT
Times cited: 41
Molecular Signature of Response to Pazopanib Salvage Therapy for Urothelial Carcinoma. Clinical genitourinary cancer. 2015 Academic Article GET IT
Times cited: 3
Somatic mutations in leukocytes infiltrating primary breast cancers. NPJ breast cancer. 2015 Academic Article GET IT
Times cited: 30
Dichotomy of Genetic Abnormalities in PEComas With Therapeutic Implications. The American journal of surgical pathology. 2015 Academic Article GET IT
Times cited: 185
Consistent copy number changes and recurrent PRKAR1A mutations distinguish Melanotic Schwannomas from Melanomas: SNP-array and next generation sequencing analysis. Genes, chromosomes & cancer. 2015 Academic Article GET IT
Times cited: 43
Cutaneous squamous and neuroendocrine carcinoma: genetically and immunohistochemically different from Merkel cell carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2015 Academic Article GET IT
Times cited: 70
Sequencing of 279 cancer genes in ampullary carcinoma reveals trends relating to histologic subtypes and frequent amplification and overexpression of ERBB2 (HER2). Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2015 Academic Article GET IT
Times cited: 58
Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping. Cancer discovery. 2015 Academic Article GET IT
Times cited: 490
A Retrospective Evaluation of Vemurafenib as Treatment for BRAF-Mutant Melanoma Brain Metastases. The oncologist. 2015 Academic Article GET IT
Times cited: 55
Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases. Cancer discovery. 2015 Academic Article GET IT
Times cited: 123
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology. The Journal of molecular diagnostics : JMD. 2015 Academic Article GET IT
Times cited: 1509
GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma. Journal of the American College of Surgeons. 2015 Academic Article GET IT
Times cited: 147
Comprehensive mutation profiling by next-generation sequencing of effusion fluids from patients with high-grade serous ovarian carcinoma. Cancer cytopathology. 2015 Academic Article GET IT
Times cited: 27
Massively parallel sequencing identifies recurrent mutations in TP53 in thymic carcinoma associated with poor prognosis. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2015 Academic Article GET IT
Times cited: 33
Pilot trial of combined BRAF and EGFR inhibition in BRAF-mutant metastatic colorectal cancer patients. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Academic Article GET IT
Times cited: 235
Clinical tumor sequencing: opportunities and challenges for precision cancer medicine. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting. 2015 Information Resource GET IT
Times cited: 48
Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor. Nature. 2014 Academic Article GET IT
Times cited: 447
PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors. Nature genetics. 2014 Academic Article GET IT
Times cited: 451
Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions. Genome biology. 2014 Academic Article GET IT
Times cited: 285
Advancing clinical oncology through genome biology and technology. Genome biology. 2014 Academic Article GET IT
Times cited: 6
Genomic predictors of survival in patients with high-grade urothelial carcinoma of the bladder. European urology. 2014 Academic Article GET IT
Times cited: 116
Detection of mutations in myeloid malignancies through paired-sample analysis of microdroplet-PCR deep sequencing data. The Journal of molecular diagnostics : JMD. 2014 Academic Article GET IT
Times cited: 25
Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle. Annals of oncology : official journal of the European Society for Medical Oncology. 2014 Academic Article GET IT
Times cited: 296
Synthetic lethality in ATM-deficient RAD50-mutant tumors underlies outlier response to cancer therapy. Cancer discovery. 2014 Academic Article GET IT
Times cited: 102
Small-cell lung cancers in patients who never smoked cigarettes. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2014 Academic Article GET IT
Times cited: 110
Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia. Science translational medicine. 2014 Academic Article GET IT
Times cited: 107
Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cancer: recognition of the syndrome by pathologic features and the utility of detecting aberrant succination by immunohistochemistry. The American journal of surgical pathology. 2014 Academic Article GET IT
Times cited: 214
PRADA: pipeline for RNA sequencing data analysis. Bioinformatics (Oxford, England). 2014 Academic Article GET IT
Times cited: 122
Recurrent SMARCA4 mutations in small cell carcinoma of the ovary. Nature genetics. 2014 Academic Article GET IT
Times cited: 277
Tumor genetic analyses of patients with metastatic renal cell carcinoma and extended benefit from mTOR inhibitor therapy. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
Times cited: 178
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence. Cancer research. 2014 Academic Article GET IT
Times cited: 247
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas. Nature communications. 2014 Academic Article GET IT
Times cited: 501
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nature genetics. 2013 Academic Article GET IT
Times cited: 923
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nature biotechnology. 2013 Academic Article GET IT
Times cited: 1700
Detecting somatic genetic alterations in tumor specimens by exon capture and massively parallel sequencing. Journal of visualized experiments : JoVE. 2013 Academic Article GET IT
Times cited: 63
Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature. 2013 Academic Article GET IT
Times cited: 1721
Punctuated evolution of prostate cancer genomes. Cell. 2013 Academic Article GET IT
Times cited: 1004
Harnessing massively parallel DNA sequencing for the personalization of cancer management. Personalized medicine. 2013 Academic Article GET IT
Times cited: 1
Phase II trial of MEK inhibitor selumetinib (AZD6244, ARRY-142886) in patients with BRAFV600E/K-mutated melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 Academic Article GET IT
Times cited: 118
BRAF mutation is associated with early stage disease and improved outcome in patients with low-grade serous ovarian cancer. Cancer. 2012 Academic Article GET IT
Times cited: 170
Genome sequencing identifies a basis for everolimus sensitivity. Science (New York, N.Y.). 2012 Article GET IT
Times cited: 594
Melanoma genome sequencing reveals frequent PREX2 mutations. Nature. 2012 Academic Article GET IT
Times cited: 599
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. 2012 Academic Article GET IT
Times cited: 5696
Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development (Cambridge, England). 2012 Academic Article GET IT
Times cited: 26
High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing. Cancer discovery. 2011 Academic Article GET IT
Times cited: 446
The mutational landscape of head and neck squamous cell carcinoma. Science (New York, N.Y.). 2011 Academic Article GET IT
Times cited: 2069
The genomic complexity of primary human prostate cancer. Nature. 2011 Academic Article GET IT
Times cited: 1026
Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL. PloS one. 2010 Academic Article GET IT
Times cited: 27
Objective sequence-based subfamily classifications of mouse homeodomains reflect their in vitro DNA-binding preferences. Nucleic acids research. 2010 Academic Article GET IT
Times cited: 2
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. The EMBO journal. 2010 Academic Article GET IT
Times cited: 441
Integrative analysis of the melanoma transcriptome. Genome research. 2010 Academic Article GET IT
Times cited: 230
Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites. Genomics. 2010 Academic Article GET IT
Times cited: 38
Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts. Genome biology. 2009 Academic Article GET IT
Times cited: 168
Applications of genomics in melanoma oncogene discovery. Hematology/oncology clinics of North America. 2009 Information Resource GET IT
Times cited: 25
Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.). 2009 Academic Article GET IT
Times cited: 771
High-resolution DNA-binding specificity analysis of yeast transcription factors. Genome research. 2009 Academic Article GET IT
Times cited: 328
Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells. Cancer research. 2009 Academic Article GET IT
Times cited: 174
Universal protein-binding microarrays for the comprehensive characterization of the DNA-binding specificities of transcription factors. Nature protocols. 2009 Academic Article GET IT
Times cited: 278
Predicting the binding preference of transcription factors to individual DNA k-mers. Bioinformatics (Oxford, England). 2008 Academic Article GET IT
Times cited: 23
The Vibrio harveyi master quorum-sensing regulator, LuxR, a TetR-type protein is both an activator and a repressor: DNA recognition and binding specificity at target promoters. Molecular microbiology. 2008 Academic Article GET IT
Times cited: 120
Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell. 2008 Academic Article GET IT
Times cited: 492
Microarray analyses of newborn mouse ovaries lacking Nobox. Biology of reproduction. 2007 Academic Article GET IT
Times cited: 110
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. Genome research. 2007 Academic Article GET IT
Times cited: 89
Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities. Nature biotechnology. 2006 Academic Article GET IT
Times cited: 532
Protein binding microarrays (PBMs) for rapid, high-throughput characterization of the sequence specificities of DNA binding proteins. Methods in molecular biology (Clifton, N.J.). 2006 Academic Article GET IT
Times cited: 74
Rapid analysis of the DNA-binding specificities of transcription factors with DNA microarrays. Nature genetics. 2004 Academic Article GET IT
Times cited: 305

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Background

education and training

Ph.D., Harvard University 2008
A.B., Princeton University 2001

Contact

full name

Michael Berger

primary email

bergerm1@mskcc.org

VIVO Weill Cornell Medical College

Michael Berger Assistant Professor of Pathology and Laboratory Medicine

Publications

selected publications

Background

education and training

Contact

full name

primary email