selected publications
- Propionate metabolism is dysregulated in non-small cell lung cancer patients and EGFR-mutant drug-tolerant persister cells. Scientific reports. 2026 Academic Article GET IT
- Propionate metabolism dysregulation promotes drug-tolerant persister cell survival in non-small cell lung cancer. 2025 GET IT
- Nutrient signaling: Starvation flips a phosphoinositide switch on lysosomal catabolism. Current biology : CB. 2023 Academic Article GET IT
- Balancing lysosome abundance in health and disease. Nature cell biology. 2023 Review GET IT
- Altered propionate metabolism contributes to tumour progression and aggressiveness. Nature metabolism. 2022 Academic Article GET IT
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Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability.
Nature communications.
2020
Academic Article
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Times cited: 73 -
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization.
Cancer cell.
2019
Academic Article
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Times cited: 77 -
Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin.
Proceedings of the National Academy of Sciences of the United States of America.
2019
Academic Article
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Times cited: 21 -
ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation.
Proceedings of the National Academy of Sciences of the United States of America.
2019
Academic Article
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Times cited: 71 -
Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK.
Molecular biology of the cell.
2015
Academic Article
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Times cited: 19 -
Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells.
Proceedings of the National Academy of Sciences of the United States of America.
2014
Academic Article
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Times cited: 114 -
Proper protein glycosylation promotes mitogen-activated protein kinase signal fidelity.
Biochemistry.
2012
Academic Article
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Times cited: 9 -
Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity.
Molecular biology of the cell.
2012
Academic Article
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Times cited: 18 -
Positive roles for negative regulators in the mating response of yeast.
Molecular systems biology.
2012
Academic Article
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Times cited: 14 -
Checkpoints in a yeast differentiation pathway coordinate signaling during hyperosmotic stress.
PLoS genetics.
2012
Academic Article
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Times cited: 41 -
Regulation of cell signaling dynamics by the protein kinase-scaffold Ste5.
Molecular cell.
2008
Academic Article
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Times cited: 102 -
Analysis of the aerobactin and ferric hydroxamate uptake systems of Yersinia pestis.
Microbiology (Reading, England).
2007
Academic Article
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Times cited: 20 -
Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2.
Proceedings of the National Academy of Sciences of the United States of America.
2006
Academic Article
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Times cited: 77 -
Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus.
Proceedings of the National Academy of Sciences of the United States of America.
2006
Academic Article
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Times cited: 164 -
Crystal structure of group A streptococcus Mac-1: insight into dimer-mediated specificity for recognition of human IgG.
Structure (London, England : 1993).
2006
Academic Article
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Times cited: 24 -
Genome sequence of a serotype M28 strain of group a streptococcus: potential new insights into puerperal sepsis and bacterial disease specificity.
The Journal of infectious diseases.
2005
Academic Article
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Times cited: 195 -
Analysis of a novel prophage-encoded group A Streptococcus extracellular phospholipase A(2).
The Journal of biological chemistry.
2004
Academic Article
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Times cited: 33 -
Histidine and aspartic acid residues important for immunoglobulin G endopeptidase activity of the group A Streptococcus opsonophagocytosis-inhibiting Mac protein.
Infection and immunity.
2003
Academic Article
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Times cited: 13