selected publications
- Increased translation driven by non-canonical EZH2 creates a synthetic vulnerability in enzalutamide-resistant prostate cancer. Nature communications. 2024 Academic Article GET IT
- ASCL1 Drives the Development of Neuroendocrine Prostate Cancer. Cancer research. 2024 Academic Article GET IT
- Distinct mesenchymal cell states mediate prostate cancer progression. Nature communications. 2024 Academic Article GET IT
- The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer. Cancer research communications. 2023 Academic Article GET IT
- Defining cellular population dynamics at single-cell resolution during prostate cancer progression. eLife. 2022 Academic Article GET IT
- STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment. Breast cancer research : BCR. 2021 Academic Article GET IT
- Extracellular Matrix in Synthetic Hydrogel-based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 inhibitors. Advanced materials (Deerfield Beach, Fla.). 2021 Academic Article GET IT
- RNA splicing factors SRRM3 and SRRM4 distinguish molecular phenotypes of castration-resistant neuroendocrine prostate cancer. Cancer research. 2021 Academic Article GET IT
- Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer. Nature communications. 2021 Academic Article GET IT
-
Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer.
Cancers.
2020
Academic Article
GET IT
Times cited: 25 -
N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.
The Journal of clinical investigation.
2019
Academic Article
GET IT
Times cited: 122 -
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors.
Proceedings of the National Academy of Sciences of the United States of America.
2019
Academic Article
GET IT
Times cited: 61 -
Cancer Stem Cell Phenotypes in ER+ Breast Cancer Models Are Promoted by PELP1/AIB1 Complexes.
Molecular cancer research : MCR.
2018
Academic Article
GET IT
Times cited: 19 -
Breast cancer cell-derived fibroblast growth factors enhance osteoclast activity and contribute to the formation of metastatic lesions.
PloS one.
2017
Academic Article
GET IT
Times cited: 25 -
STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.
Developmental biology.
2017
Academic Article
GET IT
Times cited: 23 -
Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs.
Journal of hematology & oncology.
2017
Academic Article
GET IT
Times cited: 63 -
SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts.
Nature communications.
2017
Academic Article
GET IT
Times cited: 65 - ADAM17 in tumor associated leukocytes regulates inflammatory mediators and promotes mammary tumor formation. Genes & cancer. 2016 Academic Article GET IT
-
Macrophages: Regulators of the Inflammatory Microenvironment during Mammary Gland Development and Breast Cancer.
Mediators of inflammation.
2016
Review
GET IT
Times cited: 69 -
Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival.
Molecular cancer.
2015
Academic Article
GET IT
Times cited: 26 -
Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation.
Cancer research.
2013
Academic Article
GET IT
Times cited: 57 -
Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts.
The Journal of clinical investigation.
2013
Academic Article
GET IT
Times cited: 54 -
The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2.
The Journal of experimental medicine.
2013
Academic Article
GET IT
Times cited: 51 -
The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid.
Nature cell biology.
2010
Academic Article
GET IT
Times cited: 94