selected publications
- Increased translation driven by non-canonical EZH2 creates a synthetic vulnerability in enzalutamide-resistant prostate cancer. Nature communications. 2024 Academic Article GET IT
- ASCL1 Drives the Development of Neuroendocrine Prostate Cancer. Cancer research. 2024 Academic Article GET IT
- Distinct mesenchymal cell states mediate prostate cancer progression. Nature communications. 2024 Academic Article GET IT
- The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer. Cancer research communications. 2023 Academic Article GET IT
- Defining cellular population dynamics at single-cell resolution during prostate cancer progression. eLife. 2022 Academic Article GET IT
- STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment. Breast cancer research : BCR. 2021 Academic Article GET IT
- Extracellular Matrix in Synthetic Hydrogel-based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 inhibitors. Advanced materials (Deerfield Beach, Fla.). 2021 Academic Article GET IT
- RNA splicing factors SRRM3 and SRRM4 distinguish molecular phenotypes of castration-resistant neuroendocrine prostate cancer. Cancer research. 2021 Academic Article GET IT
- Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer. Nature communications. 2021 Academic Article GET IT
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Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer.
Cancers.
2020
Academic Article
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Times cited: 25 -
N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.
The Journal of clinical investigation.
2019
Academic Article
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Times cited: 124 -
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors.
Proceedings of the National Academy of Sciences of the United States of America.
2019
Academic Article
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Times cited: 63 -
Cancer Stem Cell Phenotypes in ER+ Breast Cancer Models Are Promoted by PELP1/AIB1 Complexes.
Molecular cancer research : MCR.
2018
Academic Article
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Times cited: 19 -
Breast cancer cell-derived fibroblast growth factors enhance osteoclast activity and contribute to the formation of metastatic lesions.
PloS one.
2017
Academic Article
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Times cited: 26 -
STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.
Developmental biology.
2017
Academic Article
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Times cited: 23 -
Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs.
Journal of hematology & oncology.
2017
Academic Article
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Times cited: 64 -
SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts.
Nature communications.
2017
Academic Article
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Times cited: 65 - ADAM17 in tumor associated leukocytes regulates inflammatory mediators and promotes mammary tumor formation. Genes & cancer. 2016 Academic Article GET IT
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Macrophages: Regulators of the Inflammatory Microenvironment during Mammary Gland Development and Breast Cancer.
Mediators of inflammation.
2016
Review
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Times cited: 69 -
Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival.
Molecular cancer.
2015
Academic Article
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Times cited: 27 -
Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation.
Cancer research.
2013
Academic Article
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Times cited: 57 -
Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts.
The Journal of clinical investigation.
2013
Academic Article
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Times cited: 55 -
The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2.
The Journal of experimental medicine.
2013
Academic Article
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Times cited: 51 -
The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid.
Nature cell biology.
2010
Academic Article
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Times cited: 94