selected publications
- In Vivo Femtosecond Laser Subsurface Cortical Microtransections Attenuate Acute Rat Focal Seizures. Cerebral cortex (New York, N.Y. : 1991). 2019 Academic Article GET IT
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Preventing dementia by preventing stroke: The Berlin Manifesto.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
2019
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Times cited: 214 -
Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem cell properties.
Scientific reports.
2019
Academic Article
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Times cited: 72 -
Deep convolutional neural networks for segmenting 3D in vivo multiphoton images of vasculature in Alzheimer disease mouse models.
PloS one.
2019
Academic Article
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Times cited: 54 -
Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models.
Nature neuroscience.
2019
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Times cited: 303 -
Aspirin treatment does not increase microhemorrhage size in young or aged mice.
PloS one.
2019
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Times cited: 3 -
In Vivo Calcium Imaging of Cardiomyocytes in the Beating Mouse Heart With Multiphoton Microscopy.
Frontiers in physiology.
2018
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Times cited: 29 -
Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging.
Scientific reports.
2018
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Times cited: 25 -
Diverse Inflammatory Response After Cerebral Microbleeds Includes Coordinated Microglial Migration and Proliferation.
Stroke.
2018
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Times cited: 59 -
Label-free imaging of atherosclerotic plaques using third-harmonic generation microscopy.
Biomedical optics express.
2017
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Times cited: 15 -
Experimentally constrained circuit model of cortical arteriole networks for understanding flow redistribution due to occlusion and neural activation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2017
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Times cited: 7 -
Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations.
Nature communications.
2017
Academic Article
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Times cited: 84 -
A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal.
Molecular systems biology.
2017
Academic Article
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Times cited: 35 -
In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain.
Nature methods.
2017
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Times cited: 396 -
A circuit motif in the zebrafish hindbrain for a two alternative behavioral choice to turn left or right.
eLife.
2016
Academic Article
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Times cited: 49 -
Simultaneous optical and electrical in vivo analysis of the enteric nervous system.
Nature communications.
2016
Academic Article
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Times cited: 49 -
Use of Tethered Enzymes as a Platform Technology for Rapid Analyte Detection.
PloS one.
2015
Academic Article
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Times cited: 8 - A mathematical model relating cortical oxygenated and deoxygenated hemoglobin flows and volumes to neural activity. Journal of neural engineering. 2015 Academic Article GET IT
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Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.
Nature biotechnology.
2015
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Times cited: 27 -
Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture.
Microcirculation (New York, N.Y. : 1994).
2015
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Times cited: 69 -
Mechanistic insight into the TH1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles.
PloS one.
2014
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Times cited: 43 -
Growth and hemodynamics after early embryonic aortic arch occlusion.
Biomechanics and modeling in mechanobiology.
2014
Academic Article
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Times cited: 32 -
Stalled cerebral capillary blood flow in mouse models of essential thrombocythemia and polycythemia vera revealed by in vivo two-photon imaging.
Journal of thrombosis and haemostasis : JTH.
2014
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Times cited: 22 -
Optically induced occlusion of single blood vessels in rodent neocortex.
Cold Spring Harbor protocols.
2013
Academic Article
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Times cited: 8 -
Optoporation and genetic manipulation of cells using femtosecond laser pulses.
Biophysical journal.
2013
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Times cited: 55 -
Stimulus-evoked calcium transients in somatosensory cortex are temporarily inhibited by a nearby microhemorrhage.
PloS one.
2013
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Times cited: 35 -
Three-photon excited fluorescence imaging of unstained tissue using a GRIN lens endoscope.
Biomedical optics express.
2013
Academic Article
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Times cited: 38 -
Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2012
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Times cited: 358 -
In vivo two-photon excited fluorescence microscopy reveals cardiac- and respiration-dependent pulsatile blood flow in cortical blood vessels in mice.
American journal of physiology. Heart and circulatory physiology.
2012
Academic Article
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Times cited: 107 -
Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration.
Science translational medicine.
2011
Academic Article
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Times cited: 314 -
Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degeneration.
PloS one.
2011
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Times cited: 71 -
Real-time imaging of perivascular transport of nanoparticles during convection-enhanced delivery in the rat cortex.
Annals of biomedical engineering.
2011
Academic Article
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Times cited: 40 -
Preictal and ictal neurovascular and metabolic coupling surrounding a seizure focus.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2011
Academic Article
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Times cited: 97 -
Sub-surface, micrometer-scale incisions produced in rodent cortex using tightly-focused femtosecond laser pulses.
Lasers in surgery and medicine.
2011
Academic Article
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Times cited: 12 -
Occlusion of cortical ascending venules causes blood flow decreases, reversals in flow direction, and vessel dilation in upstream capillaries.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2011
Academic Article
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Times cited: 72 -
Limitations of collateral flow after occlusion of a single cortical penetrating arteriole.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2010
Academic Article
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Times cited: 91 -
Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects.
American journal of physiology. Heart and circulatory physiology.
2010
Academic Article
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Times cited: 27 -
Deep tissue multiphoton microscopy using longer wavelength excitation.
Optics express.
2009
Academic Article
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Times cited: 418 -
Flexible microfluidic devices supported by biodegradable insertion scaffolds for convection-enhanced neural drug delivery.
Biomedical microdevices.
2009
Academic Article
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Times cited: 39 -
Suppressed neuronal activity and concurrent arteriolar vasoconstriction may explain negative blood oxygenation level-dependent signal.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2007
Academic Article
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Times cited: 312 -
Penetrating arterioles are a bottleneck in the perfusion of neocortex.
Proceedings of the National Academy of Sciences of the United States of America.
2006
Academic Article
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Times cited: 285 -
Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke.
Nature methods.
2006
Academic Article
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Times cited: 234 -
Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion.
PLoS biology.
2006
Academic Article
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Times cited: 302 - Dynamics of femtosecond laser-induced breakdown in water from femtoseconds to microseconds. Optics express. 2002 Academic Article GET IT
- Minimally disruptive laser-induced breakdown in water. Optics letters. 1997 Academic Article GET IT