selected publications
- Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression. Nature cancer. 2024 Academic Article GET IT
- Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes. Proceedings of the National Academy of Sciences of the United States of America. 2024 Academic Article GET IT
- Human vascularized macrophage-islet organoids to model immune-mediated pancreatic β cell pyroptosis upon viral infection. Cell stem cell. 2024 Academic Article GET IT
- Human Vascularized Macrophage-Islet Organoids to Model Immune-Mediated Pancreatic β cell Pyroptosis upon Viral Infection. 2024 GET IT
- Deploying a metabolic dysfunction-associated steatohepatitis consensus care pathway: findings from an educational pilot in three health systems. BMC primary care. 2024 Academic Article GET IT
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Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.
Nature medicine.
2024
Academic Article
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Times cited: 5 - Liver-specific Mettl14 deletion induces nuclear heterotypia and dysregulates RNA export machinery. 2024 GET IT
- A nucleosome switch primes Hepatitis B Virus infection. 2024 GET IT
- Space radiation damage rescued by inhibition of key spaceflight associated miRNAs. Nature communications. 2024 Academic Article GET IT
- Author Correction: Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. 2024 GET IT
- Mesenteric Parametrial Fat Pad Surgery for in vivo Implantation of Hepatocytes in Nude Mice. Bio-protocol. 2024 Academic Article GET IT
- SARS-CoV-2 infection causes dopaminergic neuron senescence. Cell stem cell. 2024 Academic Article GET IT
- The impact of epitranscriptomic modifications on liver disease. Trends in endocrinology and metabolism: TEM. 2024 Review GET IT
- SCARPET: Site-specific quantification of methylated and non-methylated adenosines reveals m6A stoichiometry. RNA (New York, N.Y.). 2023 Academic Article GET IT
- Epinephrine inhibits PI3Kα via the Hippo kinases. Cell reports. 2023 Academic Article GET IT
- SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease. 2023 GET IT
- A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection. European journal of human genetics : EJHG. 2023 Review GET IT
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Epigenetic memory of coronavirus infection in innate immune cells and their progenitors.
Cell.
2023
Academic Article
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Times cited: 2 - Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts. Science translational medicine. 2023 Academic Article GET IT
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Targeted viral adaptation generates a simian-tropic hepatitis B virus that infects marmoset cells.
Nature communications.
2023
Academic Article
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Times cited: 5 -
Tumour extracellular vesicles and particles induce liver metabolic dysfunction.
Nature.
2023
Academic Article
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Times cited: 81 - Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines. Science advances. 2023 Academic Article GET IT
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A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection.
Nature cell biology.
2023
Academic Article
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Times cited: 10 - Evaluating sleep in covert encephalopathy with wearable technology: results from the WATCHES study. Hepatology communications. 2023 Academic Article GET IT
- Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication. Science signaling. 2022 Academic Article GET IT
- Multiple Facets of Cellular Homeostasis and Regeneration of the Mammalian Liver. Annual review of physiology. 2022 Review GET IT
- Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path. ACS bio & med chem Au. 2022 Academic Article GET IT
- A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants. Cell stem cell. 2022 Academic Article GET IT
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SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery.
Science translational medicine.
2022
Academic Article
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Times cited: 137 - Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19. Science immunology. 2022 Academic Article GET IT
- SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy. Pediatric research. 2022 Academic Article GET IT
- Molecular clones of genetically distinct hepatitis B virus genotypes reveal distinct host and drug treatment responses. JHEP reports : innovation in hepatology. 2022 Academic Article GET IT
- CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction. Nature cell biology. 2022 Academic Article GET IT
- A diminished immune response underlies age-related SARS-CoV-2 pathologies. Cell reports. 2022 Academic Article GET IT
- Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity. Cell. 2022 Letter GET IT
- Inflammatory Responses in the Placenta upon SARS-CoV-2 Infection Late in Pregnancy. iScience. 2022 Academic Article GET IT
- Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction. Cell stem cell. 2022 Academic Article GET IT
- Booster vaccines for COVID-19 vaccine breakthrough cases?. Lancet (London, England). 2022 Letter GET IT
- Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry. eLife. 2022 Academic Article GET IT
- SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells. Circulation research. 2022 Academic Article GET IT
- Human biliary epithelial cells for regenerative medicine. Cell stem cell. 2022 Comment GET IT
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System-wide transcriptome damage and tissue identity loss in COVID-19 patients.
Cell reports. Medicine.
2022
Academic Article
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Times cited: 28 -
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
2021
GET IT
Times cited: 12 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
- Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease. Cell reports. 2021 Academic Article GET IT
- An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection. Cell reports. 2021 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
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Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.
Cell metabolism.
2021
Academic Article
GET IT
Times cited: 141 - The NF-κB transcriptional footprint is essential for SARS-CoV-2 replication. Journal of virology. 2021 Academic Article GET IT
- Identifying FDA-approved drugs with multimodal properties against COVID-19 using a data-driven approach and a lung organoid model of SARS-CoV-2 entry. Molecular medicine (Cambridge, Mass.). 2021 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
- Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2. Stem cell reports. 2021 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
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SARS-CoV-2 infection induces beta cell transdifferentiation.
Cell metabolism.
2021
Academic Article
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Times cited: 134 - Cell and Tissue Therapy for the Treatment of Chronic Liver Disease. Annual review of biomedical engineering. 2021 Information Resource GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
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A molecular single-cell lung atlas of lethal COVID-19.
Nature.
2021
Academic Article
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Times cited: 10 -
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts.
Circulation research.
2021
Academic Article
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Times cited: 45 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
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The spatial landscape of lung pathology during COVID-19 progression.
Nature.
2021
Academic Article
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Times cited: 230 - Hyperglycemia in Acute COVID-19 is Characterized by Adipose Tissue Dysfunction and Insulin Resistance. 2021 GET IT
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Peptide-based scaffolds for the culture and maintenance of primary human hepatocytes.
Scientific reports.
2021
Academic Article
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Times cited: 24 -
Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions.
Nature communications.
2021
Academic Article
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Times cited: 90 -
Intestinal Host Response to SARS-CoV-2 Infection and COVID-19 Outcomes in Patients With Gastrointestinal Symptoms.
Gastroenterology.
2021
Academic Article
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Times cited: 121 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
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Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis.
JHEP reports : innovation in hepatology.
2021
Academic Article
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Times cited: 51 -
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19.
Journal of leukocyte biology.
2021
Academic Article
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Times cited: 84 -
Evolution of antibody immunity to SARS-CoV-2.
Nature.
2021
Academic Article
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Times cited: 1145 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2021 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2020 Academic Article GET IT
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Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.
Nature.
2020
Academic Article
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Times cited: 376 -
An Adhesive Hydrogel with "Load-Sharing" Effect as Tissue Bandages for Drug and Cell Delivery.
Advanced materials (Deerfield Beach, Fla.).
2020
Academic Article
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Times cited: 153 -
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis.
Nature.
2020
Academic Article
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Times cited: 153 -
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
Cell.
2020
Academic Article
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Times cited: 775 -
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
Cell stem cell.
2020
Academic Article
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Times cited: 498 -
Epidemiological evidence for association between higher influenza vaccine uptake in the elderly and lower COVID-19 deaths in Italy.
Journal of medical virology.
2020
Article
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Times cited: 133 -
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Cell.
2020
Academic Article
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Times cited: 3046 -
Gastrointestinal and Hepatic Manifestations of 2019 Novel Coronavirus Disease in a Large Cohort of Infected Patients From New York: Clinical Implications.
Gastroenterology.
2020
Academic Article
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Times cited: 115 -
Long-term in vivo biocompatibility of single-walled carbon nanotubes.
PloS one.
2020
Academic Article
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Times cited: 60 -
Hedgehog Signaling Demarcates a Niche of Fibrogenic Peribiliary Mesenchymal Cells.
Gastroenterology.
2020
Academic Article
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Times cited: 30 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2020 Academic Article GET IT
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Banning carbon nanotubes would be scientifically unjustified and damaging to innovation.
Nature nanotechnology.
2020
Article
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Times cited: 29 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
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Conservation of cell-intrinsic immune responses in diverse nonhuman primate species.
Life science alliance.
2019
Academic Article
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Times cited: 6 -
Engineering transferrable microvascular meshes for subcutaneous islet transplantation.
Nature communications.
2019
Academic Article
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Times cited: 71 -
Targeting Hepatitis B Virus Covalently Closed Circular DNA and Hepatitis B Virus X Protein: Recent Advances and New Approaches.
ACS infectious diseases.
2019
Academic Article
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Times cited: 14 -
Pre- and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells.
Nature communications.
2019
Academic Article
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Times cited: 26 -
Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma.
Cancer research.
2019
Academic Article
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Times cited: 110 -
Analysis of Host Responses to Hepatitis B and Delta Viral Infections in a Micro-scalable Hepatic Co-culture System.
Hepatology (Baltimore, Md.).
2019
Academic Article
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Times cited: 31 -
Hepatology Highlights.
Hepatology (Baltimore, Md.).
2019
Academic Article
GET IT
Times cited: 1 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
- Hepatology Highlights. Hepatology (Baltimore, Md.). 2019 Academic Article GET IT
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An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo.
Science translational medicine.
2018
Academic Article
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Times cited: 78 -
Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection.
Science translational medicine.
2018
Academic Article
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Times cited: 37 -
Co-transplantation of Human Ovarian Tissue with Engineered Endothelial Cells: A Cell-based Strategy Combining Accelerated Perfusion with Direct Paracrine Delivery.
Journal of visualized experiments : JoVE.
2018
Academic Article
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Times cited: 17 -
Identification of the Intragenomic Promoter Controlling Hepatitis E Virus Subgenomic RNA Transcription.
mBio.
2018
Academic Article
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Times cited: 28 -
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.
Nature cell biology.
2018
Academic Article
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Times cited: 1190 - Hepatology Highlights. Hepatology (Baltimore, Md.). 2018 Editorial Article GET IT
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Hepatitis E virus: advances and challenges.
Nature reviews. Gastroenterology & hepatology.
2017
Information Resource
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Times cited: 84 -
Scalable Production and Cryostorage of Organoids Using Core-Shell Decoupled Hydrogel Capsules.
Advanced biosystems.
2017
Academic Article
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Times cited: 40 - Nicotinamide N-methyltransferase expression decreases in iron overload, exacerbating toxicity in mouse hepatocytes. Hepatology communications. 2017 Academic Article GET IT
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High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain.
Cell stem cell.
2017
Academic Article
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Times cited: 199 -
Endoscopic Sleeve Gastroplasty Significantly Reduces Body Mass Index and Metabolic Complications in Obese Patients.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
2016
Academic Article
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Times cited: 101 -
Hepatocarcinogenesis associated with hepatitis B, delta and C viruses.
Current opinion in virology.
2016
Information Resource
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Times cited: 41 - Pluripotent Stem Cell-Derived Hepatocyte-like Cells: A Tool to Study Infectious Disease. Current pathobiology reports. 2016 Academic Article GET IT
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Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies.
Virology.
2016
Academic Article
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Times cited: 14 -
Engraftment of human induced pluripotent stem cell-derived hepatocytes in immunocompetent mice via 3D co-aggregation and encapsulation.
Scientific reports.
2015
Academic Article
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Times cited: 76 -
A cell culture system for distinguishing hepatitis C viruses with and without liver cancer-related mutations in the viral core gene.
Journal of hepatology.
2015
Academic Article
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Times cited: 20 -
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus.
Scientific reports.
2015
Academic Article
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Times cited: 251 -
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nature cell biology.
2015
Academic Article
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Times cited: 2063 -
Microbial-derived lithocholic acid and vitamin K2 drive the metabolic maturation of pluripotent stem cells-derived and fetal hepatocytes.
Hepatology (Baltimore, Md.).
2015
Academic Article
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Times cited: 54 -
Patterning vascular networks in vivo for tissue engineering applications.
Tissue engineering. Part C, Methods.
2015
Academic Article
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Times cited: 48 -
Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro.
Stem cell reports.
2015
Academic Article
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Times cited: 105 -
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems.
Proceedings of the National Academy of Sciences of the United States of America.
2014
Academic Article
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Times cited: 213 -
Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues.
Tissue engineering. Part A.
2014
Academic Article
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Times cited: 109 -
Pluripotent stem cell-derived hepatocyte-like cells.
Biotechnology advances.
2014
Information Resource
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Times cited: 234 -
Discovery and development of first in class antifungal caspofungin (CANCIDAS®)--a case study.
Natural product reports.
2014
Information Resource
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Times cited: 78 -
Identification of small molecules for human hepatocyte expansion and iPS differentiation.
Nature chemical biology.
2013
Academic Article
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Times cited: 218 -
InVERT molding for scalable control of tissue microarchitecture.
Nature communications.
2013
Academic Article
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Times cited: 112 -
Modeling hepatitis C virus infection using human induced pluripotent stem cells.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
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Times cited: 196 -
Esophageal stem cells and 3D-cell culture models.
Annals of the New York Academy of Sciences.
2011
Academic Article
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Times cited: 5 -
Humanized mice with ectopic artificial liver tissues.
Proceedings of the National Academy of Sciences of the United States of America.
2011
Academic Article
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Times cited: 139 -
Hepatic stem cells.
Methods in molecular biology (Clifton, N.J.).
2010
Information Resource
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Times cited: 12 -
Isolation and characterization of a novel population of progenitor cells from unmanipulated rat liver.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
2008
Academic Article
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Times cited: 39 -
Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro.
Tissue engineering.
2006
Academic Article
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Times cited: 64 -
Defined conditions for development of functional hepatic cells from human embryonic stem cells.
Stem cells and development.
2005
Academic Article
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Times cited: 107 - Laser-guided direct writing for three-dimensional tissue engineering. Biotechnology and bioengineering. 2005 Academic Article GET IT
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Morphine stimulates angiogenesis by activating proangiogenic and survival-promoting signaling and promotes breast tumor growth.
Cancer research.
2002
Academic Article
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Times cited: 435 -
Pluripotency of mesenchymal stem cells derived from adult marrow.
Nature.
2002
Academic Article
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Times cited: 4977 -
Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells.
The Journal of clinical investigation.
2002
Academic Article
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Times cited: 1148 -
Arthroscopically assisted reconstruction of the anterior cruciate ligament: initial clinical experience and minimal 2-year follow-up comparing endoscopic transtibial and two-incision techniques.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.
1997
Academic Article
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Times cited: 45