Park, Sae Woong

Publications

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selected publications

Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin. Nature communications. 2024 Academic Article GET IT
Mycobacterial Regulatory Systems Involved in the Regulation of Gene Expression Under Respiration-Inhibitory Conditions. Journal of microbiology (Seoul, Korea). 2023 Review GET IT
Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice. eLife. 2022 Academic Article GET IT
Nonredundant functions of Mycobacterium tuberculosis chaperones promote survival under stress. Molecular microbiology. 2020 Academic Article GET IT
Times cited: 4
Activity-Based Protein Profiling Reveals That Cephalosporins Selectively Active on Non-replicating Mycobacterium tuberculosis Bind Multiple Protein Families and Spare Peptidoglycan Transpeptidases. Frontiers in microbiology. 2020 Academic Article GET IT
Times cited: 13
Investigation of ( S)-(-)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin Synthase. ACS infectious diseases. 2019 Academic Article GET IT
Times cited: 28
Promotion of tumor progression and cancer stemness by MUC15 in thyroid cancer via the GPCR/ERK and integrin-FAK signaling pathways. Oncogenesis. 2018 Academic Article GET IT
Times cited: 30
Roles of Alanine Dehydrogenase and Induction of Its Gene in Mycobacterium smegmatis under Respiration-Inhibitory Conditions. Journal of bacteriology. 2018 Academic Article GET IT
Times cited: 25
Targeting protein biotinylation enhances tuberculosis chemotherapy. Science translational medicine. 2018 Academic Article GET IT
Times cited: 28
Conformationally Constrained Cinnolinone Nucleoside Analogues as Siderophore Biosynthesis Inhibitors for Tuberculosis. ACS medicinal chemistry letters. 2018 Academic Article GET IT
Times cited: 26
Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy. 2017 Academic Article GET IT
Times cited: 79
Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis. Journal of medicinal chemistry. 2017 Academic Article GET IT
Times cited: 33
Identification and characterization of the genes encoding carbon monoxide dehydrogenase in Terrabacter carboxydivorans. Research in microbiology. 2017 Academic Article GET IT
Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis. mBio. 2017 Academic Article GET IT
Times cited: 452
Functional characterization of the cutI gene for the transcription of carbon monoxide dehydrogenase genes in Mycobacterium sp. strain JC1 DSM 3803. Journal of microbiology (Seoul, Korea). 2016 Academic Article GET IT
Times cited: 1
Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA. Journal of medicinal chemistry. 2015 Academic Article GET IT
Times cited: 32
Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis. Chemistry & biology. 2014 Academic Article GET IT
Times cited: 46
Perturbation of cytochrome c maturation reveals adaptability of the respiratory chain in Mycobacterium tuberculosis. mBio. 2013 Academic Article GET IT
Times cited: 66
Microbiology and genetics of CO utilization in mycobacteria. Antonie van Leeuwenhoek. 2012 Information Resource GET IT
Times cited: 7
Mechanism-based inactivation by aromatization of the transaminase BioA involved in biotin biosynthesis in Mycobaterium tuberculosis. Journal of the American Chemical Society. 2011 Academic Article GET IT
Times cited: 39
Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression. PLoS pathogens. 2011 Academic Article GET IT
Times cited: 127
Identification of trans- and cis-control elements involved in regulation of the carbon monoxide dehydrogenase genes in Mycobacterium sp. strain JC1 DSM 3803. Journal of bacteriology. 2010 Academic Article GET IT
Times cited: 14
Terrabacter carboxydivorans sp. nov., a carbon monoxide-oxidizing actinomycete. International journal of systematic and evolutionary microbiology. 2010 Academic Article GET IT
Times cited: 6
Cloning and expression analysis of the duplicated genes for carbon monoxide dehydrogenase of Mycobacterium sp. strain JC1 DSM 3803. Microbiology (Reading, England). 2009 Academic Article GET IT
Times cited: 14
Expression and regulation of ribulose 1,5-bisphosphate carboxylase/oxygenase genes in Mycobacterium sp. strain JC1 DSM 3803. Journal of microbiology (Seoul, Korea). 2009 Academic Article GET IT
Times cited: 10
Tsukamurella carboxydivorans sp. nov., a carbon monoxide-oxidizing actinomycete. International journal of systematic and evolutionary microbiology. 2009 Academic Article GET IT
Times cited: 19
Presence of duplicate genes encoding a phylogenetically new subgroup of form I ribulose 1,5-bisphosphate carboxylase/oxygenase in Mycobacterium sp. strain JC1 DSM 3803. Research in microbiology. 2008 Academic Article GET IT
Times cited: 18
Pseudonocardia carboxydivorans sp. nov., a carbon monoxide-oxidizing actinomycete, and an emended description of the genus Pseudonocardia. International journal of systematic and evolutionary microbiology. 2008 Academic Article GET IT
Times cited: 49
O2- and NO-sensing mechanism through the DevSR two-component system in Mycobacterium smegmatis. Journal of bacteriology. 2008 Academic Article GET IT
Times cited: 45
Cloning, characterization and expression of a gene encoding dihydroxyacetone synthase in Mycobacterium sp. strain JC1 DSM 3803. Microbiology (Reading, England). 2007 Academic Article GET IT
Times cited: 7
Carbon monoxide dehydrogenase in mycobacteria possesses a nitric oxide dehydrogenase activity. Biochemical and biophysical research communications. 2007 Academic Article GET IT
Times cited: 19
Growth of mycobacteria on carbon monoxide and methanol. Journal of bacteriology. 2003 Academic Article GET IT
Times cited: 73

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Research

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Funding awarded

Understanding resistance and tolerance to nitroimidazoles in Mycobacterium tuberculosis awarded by National Institute of Allergy & Infectious Diseases Co-Investigator 2025 - 2029
missing activity Co-Investigator 2020 - 2025

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Background

education and training

Ph.D., Yonsei University (Korea) 2006
M.S., Yonsei University (Korea) 2001
B.S., Yonsei University (Korea) 1999

Contact

full name

Sae Woong Park

primary email

sap2015@med.cornell.edu

VIVO Weill Cornell Medical College

Sae Woong Park Assistant Professor of Microbiology and Immunology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email