The Journal of investigative dermatology
Journal
Overview
publication venue for
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Plasmacytoid dendritic cells are not major producers of type 1 interferon in cutaneous lupus: An in depth immunoprofile of subacute and discoid lupus.
2023
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Expert Agreement on the Presence and Spatial Localization of Melanocytic Features in Dermoscopy..
144.
2023
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Genomic Profiling of the Overlap Phenotype between Psoriasis and Atopic Dermatitis..
144.
2023
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Best Practices for Clinical Skin Image Acquisition in Translational Artificial Intelligence Research..
143.
2023
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Distinct cAMP signaling microdomains differentially regulate melanosomal pH and pigmentation.
2023
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Staphylococcus Aureus and Streptococcus Pyogenes Induce Psoriasis-Related Transcriptomes Augmented by IL-17A and TNF-α..
143.
2023
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Improving Artificial Intelligence-Based Diagnosis on Pediatric Skin Lesions..
143.
2023
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Cathelicidin Antimicrobial Peptide LL37 Induces Toll-Like Receptor 8 and Amplifies IL-36γ and IL-17C in Human Keratinocytes..
143.
2022
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Comparison of the Inflammatory Circuits in Psoriasis Vulgaris, Non-Pustular Palmoplantar Psoriasis, and Palmoplantar Pustular Psoriasis.
2022
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ANALYZING THE SPATIAL RANDOMNESS IN THE DISTRIBUTION OF ACQUIRED MELANOCYTIC NEOPLASMS.
2022
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Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome..
142.
2022
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Associations between TERT Promoter Mutations and Survival in Superficial Spreading and Nodular Melanomas in a Large Prospective Patient Cohort..
142.
2022
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Transcriptomic Analysis of the Major Orphan Ichthyosis Subtypes Reveals Shared Immune and Barrier Signatures.
2022
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Health-related quality of life differs by race/ethnicity in North American patients with psoriasis: results from PSOLAR.
2022
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BMPR1a Is Required for the Optimal TGFβ1-Dependent CD207+ Langerhans Cell Differentiation and Limits Skin Inflammation through CD11c+ Cells..
142.
2022
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An Epidemiologic Analysis of Melanoma Overdiagnosis in the United States, 1975-2017.
2021
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A Randomized Open Label Clinical Trial of Lipid-Lowering Therapy in Psoriasis to Reduce Vascular Endothelial Inflammation.
2021
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Deep Learning and Pathomics Analyses Reveal Cell Nuclei as Important Features for Mutation Prediction of BRAF-Mutated Melanomas..
142.
2021
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Classification of Basal Cell Carcinoma in Ex Vivo Confocal Microscopy Images from Freshly Excised Tissues Using a Deep Learning Algorithm.
2021
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Chlamydia trachomatis Stimulation Enhances HIV-1 Susceptibility through the Modulation of a Member of the Macrophage Inflammatory Proteins..
142.
2021
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Differences in Psychometric Properties of Clinician and Patient-reported Outcome Measures for Atopic Dermatitis By Race and Skin Tone: A Systematic Review.
2021
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Deep Learning for Basal Cell Carcinoma Detection for Reflectance Confocal Microscopy..
142.
2021
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Increased risk of skin cancer in 1851 long-term retinoblastoma survivors.
2021
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In-Depth Analysis of the Hidradenitis Suppurativa Serum Proteome Identifies Distinct Inflammatory Subtypes..
141.
2021
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Measurement of Melanin Metabolism in Live Cells by [U-13C]-L-Tyrosine Fate Tracing Using Liquid Chromatography-Mass Spectrometry..
141.
2021
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Characterization of PCSK9 in the Blood and Skin of Psoriasis..
141.
2020
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TERT, BRAF, and NRAS Mutational Heterogeneity between Paired Primary and Metastatic Melanoma Tumors..
140.
2020
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Molecular and Cellular Responses to the TYK2/JAK1 Inhibitor PF-06700841 Reveal Reduction of Skin Inflammation in Plaque Psoriasis..
140.
2020
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Decreased CCN3 in Systemic Sclerosis Endothelial Cells Contributes to Impaired Angiogenesis..
140.
2020
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Persistence of Inflammatory Phenotype in Residual Psoriatic Plaques in Patients on Effective Biologic Therapy..
140.
2019
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Early Quantification of Systemic Inflammatory Proteins Predicts Long-Term Treatment Response to Tofacitinib and Etanercept..
140.
2019
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IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis..
140.
2019
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Revisiting the Clinical and Biologic Relevance of Partial PTEN Loss in Melanoma..
139.
2018
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Inherited Genetic Variants Associated with Melanoma BRAF/NRAS Subtypes..
138.
2018
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Mutated MITF-E87R in Melanoma Enhances Tumor Progression via S100A4..
138.
2018
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The Major Orphan Forms of Ichthyosis Are Characterized by Systemic T-Cell Activation and Th-17/Tc-17/Th-22/Tc-22 Polarization in Blood..
138.
2018
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Cooling Relief of Acute and Chronic Itch Requires TRPM8 Channels and Neurons..
138.
2017
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Reduction of Inflammatory and Cardiovascular Proteins in the Blood of Patients with Psoriasis: Differential Responses between Tofacitinib and Etanercept after 4 Weeks of Treatment..
138.
2017
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Associations of MC1R Genotype and Patient Phenotypes with BRAF and NRAS Mutations in Melanoma..
137.
2017
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Inhibition of β-Catenin Signaling in the Skin Rescues Cutaneous Adipogenesis in Systemic Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial of C-82..
137.
2017
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TNF-α Antagonist and Vascular Inflammation in Patients with Psoriasis Vulgaris: A Randomized Placebo-Controlled Study..
137.
2017
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Phenformin Enhances the Efficacy of ERK Inhibition in NF1-Mutant Melanoma..
137.
2017
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An Integrated Model of Atopic Dermatitis Biomarkers Highlights the Systemic Nature of the Disease..
137.
2016
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Shrinking the Psoriasis Assessment Gap: Early Gene-Expression Profiling Accurately Predicts Response to Long-Term Treatment..
137.
2016
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A Proteome-Derived Longitudinal Pharmacodynamic Biomarker for Diffuse Systemic Sclerosis Skin..
137.
2016
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Discrimination of Dysplastic Nevi from Common Melanocytic Nevi by Cellular and Molecular Criteria..
136.
2016
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The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes..
136.
2016
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Research Techniques Made Simple: Drug Delivery Techniques, Part 2: Commonly Used Techniques to Assess Topical Drug Bioavailability..
136.
2016
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IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing..
136.
2016
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Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes but Different Regulatory Gene Sets..
136.
2016
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Lymphatic Function Regulates Contact Hypersensitivity Dermatitis in Obesity..
135.
2015
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Aurora Kinase A Is Upregulated in Cutaneous T-Cell Lymphoma and Represents a Potential Therapeutic Target..
135.
2015
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Fidgetin-Like 2: A Microtubule-Based Regulator of Wound Healing..
135.
2015
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The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging..
135.
2015
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Assessment of cancer cell line representativeness using microarrays for Merkel cell carcinoma..
135.
2014
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Automated delineation of dermal-epidermal junction in reflectance confocal microscopy image stacks of human skin..
135.
2014
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Molecular characterization of human skin response to diphencyprone at peak and resolution phases: therapeutic insights..
134.
2014
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Dissection of immune gene networks in primary melanoma tumors critical for antitumor surveillance of patients with stage II-III resectable disease..
134.
2014
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Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells..
134.
2013
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Gene expression profiling of the leading edge of cutaneous squamous cell carcinoma: IL-24-driven MMP-7..
134.
2013
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Longitudinal study of recurrent metastatic melanoma cell lines underscores the individuality of cancer biology..
134.
2013
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Dominant Th1 and minimal Th17 skewing in discoid lupus revealed by transcriptomic comparison with psoriasis..
134.
2013
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IL-17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis..
133.
2013
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Predictors of squamous cell carcinoma in high-risk patients in the VATTC trial..
133.
2013
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β-Catenin promotes the differentiation of epidermal Langerhans dendritic cells..
133.
2013
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Gene profiling of narrowband UVB-induced skin injury defines cellular and molecular innate immune responses..
133.
2012
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Predictors of basal cell carcinoma in high-risk patients in the VATTC (VA Topical Tretinoin Chemoprevention) trial..
132.
2012
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Expanding the psoriasis disease profile: interrogation of the skin and serum of patients with moderate-to-severe psoriasis..
132.
2012
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Stromal fibroblast-specific expression of ADAM-9 modulates proliferation and apoptosis in melanoma cells in vitro and in vivo..
132.
2012
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Histology-specific microRNA alterations in melanoma..
132.
2012
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Protective effect of human endogenous retrovirus K dUTPase variants on psoriasis susceptibility..
132.
2012
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Combined use of laser capture microdissection and cDNA microarray analysis identifies locally expressed disease-related genes in focal regions of psoriasis vulgaris skin lesions..
132.
2012
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Langerhans cells from human cutaneous squamous cell carcinoma induce strong type 1 immunity..
132.
2012
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Investigation of the effect of MDM2 SNP309 and TP53 Arg72Pro polymorphisms on the age of onset of cutaneous melanoma..
132.
2012
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A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin..
132.
2012
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Human keratinocytes' response to injury upregulates CCL20 and other genes linking innate and adaptive immunity..
132.
2011
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Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-β1-dependent human epidermal Langerhans cells..
131.
2011
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Clinical and dermoscopic stability and volatility of melanocytic nevi in a population-based cohort of children in Framingham school system..
131.
2011
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TNF-α downregulates filaggrin and loricrin through c-Jun N-terminal kinase: role for TNF-α antagonists to improve skin barrier..
131.
2011
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Tumor-associated macrophages in the cutaneous SCC microenvironment are heterogeneously activated..
131.
2011
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Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis..
131.
2010
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Resolved psoriasis lesions retain expression of a subset of disease-related genes..
131.
2010
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The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C..
131.
2010
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A subpopulation of CD163-positive macrophages is classically activated in psoriasis..
130.
2010
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Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques..
130.
2010
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Soluble adenylyl cyclase defines a nuclear cAMP microdomain in keratinocyte hyperproliferative skin diseases..
130.
2010
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Myeloid dendritic cells from human cutaneous squamous cell carcinoma are poor stimulators of T-cell proliferation..
129.
2009
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Evaluation of the clonal origin of multiple primary melanomas using molecular profiling..
129.
2009
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Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells..
129.
2008
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Effect of therapeutic integrin (CD11a) blockade with efalizumab on immune responses to model antigens in humans: results of a randomized, single blind study..
128.
2008
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Neurotrophins and their receptors stimulate melanoma cell proliferation and migration..
128.
2008
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Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness..
128.
2008
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Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells..
128.
2008
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Cellular genomic maps help dissect pathology in human skin disease..
128.
2007
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Insights into gene modulation by therapeutic TNF and IFNgamma antibodies: TNF regulates IFNgamma production by T cells and TNF-regulated genes linked to psoriasis transcriptome..
128.
2007
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Aaron Lerner: perspectives and lessons learned from the melatonin days..
127.
2007
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Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment..
127.
2007
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CGRP, PACAP, and VIP modulate Langerhans cell function by inhibiting NF-kappaB activation..
127.
2007
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CDKN2A germline mutations in individuals with cutaneous malignant melanoma..
127.
2007
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ATPgammaS enhances the production of inflammatory mediators by a human dermal endothelial cell line via purinergic receptor signaling..
126.
2006
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Prominent production of IL-20 by CD68+/CD11c+ myeloid-derived cells in psoriasis: Gene regulation and cellular effects..
126.
2006
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Delayed cutaneous wound healing in mice lacking solute carrier 11a1 (formerly Nramp1): correlation with decreased expression of secretory leukocyte protease inhibitor..
126.
2006
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Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia..
126.
2006
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Dual mode reflectance and fluorescence confocal laser scanning microscopy for in vivo imaging melanoma progression in murine skin..
125.
2005
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Distinction of desmoplastic melanoma from non-desmoplastic melanoma by gene expression profiling..
124.
2005
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Relationship of treatment delay with surgical defect size from keratinocyte carcinoma (basal cell carcinoma and squamous cell carcinoma of the skin)..
124.
2005
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Dietary lutein reduces ultraviolet radiation-induced inflammation and immunosuppression..
122.
2004
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Thalidomide inhibits tumor necrosis factor-alpha production and antigen presentation by Langerhans cells..
121.
2003
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Confocal examination of nonmelanoma cancers in thick skin excisions to potentially guide mohs micrographic surgery without frozen histopathology..
117.
2001
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Stress-induced changes in skin barrier function in healthy women..
117.
2001
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Topographic variations in normal skin, as viewed by in vivo reflectance confocal microscopy..
116.
2001
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Anti-CD11a treatment for psoriasis concurrently increases circulating T-cells and decreases plaque T-cells, consistent with inhibition of cutaneous T-cell trafficking.
115.
2000
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Intravenous administration of RNA suppresses the induction of delayed-type hypersensitivity (DTH) to tumor-associated antigens.
115.
2000
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Tumor antigen presentation by dermal antigen-presenting cells..
115.
2000
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FRAP DNA-dependent protein kinase mediates a late signal transduced from ultraviolet-induced DNA damage..
114.
2000
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Induction of anti-tumor immunity with epidermal cells pulsed with tumor-derived RNA or intradermal administration of RNA..
114.
2000
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Granulocyte-macrophage colony-stimulating factor gene transfer to dendritic cells or epidermal cells augments their antigen-presenting function including induction of anti-tumor immunity..
113.
1999
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The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients..
113.
1999
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In vivo confocal scanning laser microscopy of human skin II: advances in instrumentation and comparison with histology..
113.
1999
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Rat preputial sebocyte differentiation involves peroxisome proliferator-activated receptors..
112.
1999
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Differential regulation of epidermal cell tumor-antigen presentation by IL-1alpha and IL-1beta..
111.
1998
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Localization and characterization of the RNA binding protein TLS in skin and stratified mucosa..
110.
1998
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Expression of neurotrophic factors and neuropeptide receptors by Langerhans cells and the Langerhans cell-like cell line XS52: further support for a functional relationship between Langerhans cells and epidermal nerves..
109.
1997
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Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique..
108.
1997
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Calcitonin gene-related peptide inhibits proliferation and antigen presentation by human peripheral blood mononuclear cells: effects on B7, interleukin 10, and interleukin 12..
108.
1997
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Langerhans cells express inducible nitric oxide synthase and produce nitric oxide..
107.
1996
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Impaired immunosuppressive response to ultraviolet radiation in interleukin-10-deficient mice..
107.
1996
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Inhibition of neutrophil elastase suppresses the development of skin tumors in hairless mice..
107.
1996
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Hyporesponsiveness in contact hypersensitivity and irritant contact dermatitis in CD4 gene targeted mouse..
106.
1996
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The insulin-like growth factor 1 receptor is expressed by epithelial cells with proliferative potential in human epidermis and skin appendages: correlation of increased expression with epidermal hyperplasia..
106.
1996
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Melanocyte differentiation marker gp75, the brown locus protein, can be regulated independently of tyrosinase and pigmentation..
105.
1995
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In vivo confocal scanning laser microscopy of human skin: melanin provides strong contrast..
104.
1995
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Structure-function relations in the inhibition of murine contact hypersensitivity by amiloride..
104.
1995
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Experimental photoaging in C3H/HeN, C3H/HeJ, and Balb/c mice: comparison of changes in extracellular matrix components and mast cell numbers..
103.
1994
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GM-CSF activates regenerative epidermal growth and stimulates keratinocyte proliferation in human skin in vivo..
103.
1994
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Ex vivo and in vivo gene transfer to the skin using replication-deficient recombinant adenovirus vectors..
102.
1994
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Interleukin 1 alpha but not transforming growth factor beta inhibits tumor antigen presentation by epidermal antigen-presenting cells..
102.
1994
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A cohort study of melanoma in patients with dysplastic nevi..
100.
1993
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Growth regulation of cultured human nevus cells..
100.
1993
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Anthralin decreases keratinocyte TGF-alpha expression and EGF-receptor binding in vitro..
98.
1992
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Cyclosporin increases granulocyte/macrophage colony-stimulating factor (GM-CSF) activity and gene expression in murine keratinocytes..
98.
1992
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Studies of the effect of cyclosporine in psoriasis in vivo: combined effects on activated T lymphocytes and epidermal regenerative maturation..
98.
1992
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Junctional epidermolysis bullosa keratinocytes in culture display adhesive, structural, and functional abnormalities..
97.
1991
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Regulation of GM-CSF and IL-3 production from the murine keratinocyte cell line PAM 212 following exposure to ultraviolet radiation..
97.
1991
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Increased dermal expression of platelet-derived growth factor receptors in growth-activated skin wounds and psoriasis..
96.
1991
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Tigliane-type phorbols stimulate human melanocyte proliferation: potentially safer agents for melanocyte culture..
96.
1991
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Synergistic effects of epidermal growth factor (EGF) and insulin-like growth factor I/somatomedin C (IGF-I) on keratinocyte proliferation may be mediated by IGF-I transmodulation of the EGF receptor..
96.
1991
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Longwave ultraviolet radiation (UVA, 320-400 nm)-induced tan protects human skin against further UVA injury..
93.
1989
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Erythrocyte uroporphyrinogen decarboxylase activity in porphyria cutanea tarda: a study of 40 consecutive patients..
93.
1989
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The systemic administration of gamma interferon inhibits collagen synthesis and acute inflammation in a murine skin wounding model..
93.
1989
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Induction of dermal and subcutaneous inflammation by recombinant cachectin/tumor necrosis factor (TNF alpha) in the mouse..
91.
1988
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Evidence for histamine in the urticating hairs of Hylesia moths..
88.
1987
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Prolongation of murine skin allograft survival by the systemic effects of 8-methoxypsoralen and long-wave ultraviolet radiation (PUVA)..
88.
1987
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Enhancement of the elicitation phase of the murine contact hypersensitivity response by prior exposure to local ultraviolet radiation..
86.
1986
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Purification and in vitro growth of human epidermal basal keratinocytes using a monoclonal antibody..
85.
1985
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Human complement receptors for C3b (CR1) and C3d (CR2)..
85.
1985
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Epidermal I-J-bearing cells are responsible for transferable suppressor cell generation after immunization of mice with ultraviolet radiation-treated epidermal cells..
84.
1985
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Association of HLA-DR5 with mycosis fungoides..
80.
1983
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The role of UVB radiation in the induction and elicitation of photocontact hypersensitivity to TCSA in the mouse..
80.
1983
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The collagen alpha-2 chain gene..
79 Suppl 1.
1982
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The molecular aspects of elastin gene expression..
79 Suppl 1.
1982
-
Induction of lymphocyte differentiation by epidermal cultures..
77.
1981
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Cell cycle analysis of cultured mammalian cells after exposure to 4,5',8-trimethylpsoralen and long-wave ultraviolet light..
76.
1981
-
Proliferative response patterns of human fibroblasts after photoinjury with 4,5',8-trimethylpsoralen..
76.
1981
-
Chlorpromazine phototoxicity: growth inhibition and DNA-interaction in normal human fibroblasts..
75.
1980
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Mononuclear phagocyte antimicrobial and antitumor activity: the role of oxygen intermediates..
74.
1980
-
Studies in porphyria. VI. Biosynthesis of porphyrins in mammalian skin and in the skin of porphyric patients..
68.
1977
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IL-17C: A Unique Epithelial Cytokine with Potential for Targeting across the Spectrum of Atopic Dermatitis and Psoriasis..
138.
2018
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Docosahexaenoic Acid alleviates atopic dermatitis in mice by generating T regulatory cells and m2 macrophages..
135.
2015
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Silver sulfadiazine retards wound healing in mice via alterations in cytokine expression..
135.
2015
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IL-17 induces inflammation-associated gene products in blood monocytes, and treatment with ixekizumab reduces their expression in psoriasis patient blood..
134.
2014
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Crossing the barrier: STRA6 in epidermal differentiation..
134.
2014
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Factors associated with nevus volatility in early adolescence..
134.
2014
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Dermal clusters of mature dendritic cells and T cells are associated with the CCL20/CCR6 chemokine system in chronic psoriasis..
134.
2013
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Creation of differentiation-specific genomic maps of human epidermis through laser capture microdissection..
133.
2013
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Epidermal ADAM17 is dispensable for notch activation..
133.
2013
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Risk of skin cancer associated with the use of UV nail lamp..
133.
2012
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Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial..
132.
2012
-
Transcriptional profiling of psoriasis using RNA-seq reveals previously unidentified differentially expressed genes..
132.
2011
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Deletion of PTENP1 pseudogene in human melanoma..
131.
2011
-
Interaction of CDKN2A and sun exposure in the etiology of melanoma in the general population..
131.
2011
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Melanoma molecular subtypes: unifying and paradoxical results..
130.
2010
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Relationship between germline MC1R variants and BRAF-mutant melanoma in a North Carolina population-based study..
130.
2009
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Double-blind, placebo-controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis..
129.
2009
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Increased JunB mRNA and protein expression in psoriasis vulgaris lesions..
126.
2006
-
Bringing histology to the bedside..
124.
2005
-
Non-invasive (real-time) imaging of histologic margin of a proliferative skin lesion in vivo..
111.
1998
-
In Vitro and Ex Vivo Investigation of Intralesional Sodium Thiosulfate as a Reversal Agent for Calcium Hydroxylapatite Soft Tissue Filler.
2022
-
Inherited Melanoma Risk Variants Associated with Histopathologically Amelanotic Melanoma.
2019
-
Relationship of Chromosome Arm 10q Variants to Occurrence of Multiple Primary Melanoma in the Population-Based Genes, Environment, and Melanoma (GEM) Study.
2018
-
Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF(V600E) Melanoma.
2015
-
Stress and the skin: a meeting report of the Weill Cornell Symposium on the Science of Dermatology.
2006
-
The ever-evolving landscape for detection of early melanoma: challenges and promises..
133.
2013
-
The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings.
2012
-
Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions.
2010
-
Resident and "inflammatory" dendritic cells in human skin.
2008
-
Type I Interferons in Autoimmunity.
2022
-
Immune Checkpoint Blockade and Skin Toxicity Pathogenesis.
2021
-
Research Techniques Made Simple: Drug Delivery Techniques, Part 1: Concepts in Transepidermal Penetration and Absorption.
2015
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