Immunity Journal

Overview

publication venue for

• Dendritic cells can prime anti-tumor CD8⁺ T cell responses through major histocompatibility complex cross-dressing. 2022
• Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis. 2022
• Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus. 2020
• The Transcription Factor Ets1 Suppresses T Follicular Helper Type 2 Cell Differentiation to Halt the Onset of Systemic Lupus Erythematosus. 2019
• Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells..  57. 2024
• Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8⁺ T cell effector functions. 2024
• An atlas of cells in the human tonsil. 2024
• Sex-biased gut dopamine signaling in multiple sclerosis..  56. 2023
• Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis..  56. 2023
• CD8⁺ T cells promote HIV latency by remodeling CD4⁺ T cell metabolism to enhance their survival, quiescence, and stemness. 2023
• Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup. 2023
• The ectonucleotidase CD39 identifies tumor-reactive CD8⁺ T cells predictive of immune checkpoint blockade efficacy in human lung cancer. 2022
• Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition..  55. 2022
• Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer..  55. 2022
• The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis..  55. 2022
• Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells..  55. 2022
• Phage display of environmental protein toxins and virulence factors reveals the prevalence, persistence, and genetics of antibody responses. 2022
• Dendritic cells can prime anti-tumor CD8⁺ T cell responses through major histocompatibility complex cross-dressing..  55. 2022
• Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway..  55. 2022
• IL-17RA-signaling in Lgr5⁺ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment..  55. 2022
• Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8⁺ T cells in tumors..  54. 2021
• Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses..  54. 2021
• Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets..  54. 2021
• The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design..  54. 2021
• A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance..  54. 2021
• Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer..  54. 2021
• Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes..  54. 2021
• Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery..  54. 2021
• The Transcription Factor Foxp3 Shapes Regulatory T Cell Identity by Tuning the Activity of trans-Acting Intermediaries..  53. 2020
• Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses..  53. 2020
• In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors..  53. 2020
• Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis..  52. 2020
• The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling..  52. 2020
• Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity..  52. 2020
• Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function..  51. 2019
• Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses..  51. 2019
• Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation..  51. 2019
• The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair..  51. 2019
• T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation..  51. 2019
• Cytomegalovirus Infection Drives Avidity Selection of Natural Killer Cells..  50. 2019
• Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells..  50. 2019
• Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity..  50. 2019
• Dengue Virus Immunity Increases Zika Virus-Induced Damage during Pregnancy..  50. 2019
• A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells..  50. 2019
• The Transcription Factor Ets1 Suppresses T Follicular Helper Type 2 Cell Differentiation to Halt the Onset of Systemic Lupus Erythematosus..  49. 2018
• Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis..  49. 2018
• Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance..  49. 2018
• Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers..  50. 2018
• Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus..  49. 2018
• Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44..  49. 2018
• Critical Role for the Microbiota in CX₃CR1⁺ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses..  49. 2018
• Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance..  48. 2018
• Anti-apoptotic Protein BIRC5 Maintains Survival of HIV-1-Infected CD4⁺ T Cells..  48. 2018
• Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses..  48. 2018
• Sensing Microbial Viability through Bacterial RNA Augments T Follicular Helper Cell and Antibody Responses..  48. 2018
• Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c⁺CD103⁺ Monocytic Antigen-Presenting Cells in Tumors..  48. 2018
• Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity..  47. 2017
• Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4⁺ T Cell Dysfunction..  47. 2017
• White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection..  47. 2017
• Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF..  47. 2017
• Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis..  47. 2017
• Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals..  47. 2017
• Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches..  46. 2017
• A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure..  46. 2017
• Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life..  46. 2017
• The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity..  46. 2017
• A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells..  46. 2017
• Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation..  45. 2016
• Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer..  45. 2016
• Antiviral CD8⁺ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion..  45. 2016
• Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects..  45. 2016
• Liver-Resident Memory CD8⁺ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection..  45. 2016
• Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region..  45. 2016
• mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation..  45. 2016
• Cell-Extrinsic MHC Class I Molecule Engagement Augments Human NK Cell Education Programmed by Cell-Intrinsic MHC Class I..  45. 2016
• The Costimulatory Receptor OX40 Inhibits Interleukin-17 Expression through Activation of Repressive Chromatin Remodeling Pathways..  44. 2016
• Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability..  44. 2016
• Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism..  44. 2016
• Gut Microbiota-Induced Immunoglobulin G Controls Systemic Infection by Symbiotic Bacteria and Pathogens..  44. 2016
• Interleukin-35 Limits Anti-Tumor Immunity..  44. 2016
• Clonal Abundance of Tumor-Specific CD4(+) T Cells Potentiates Efficacy and Alters Susceptibility to Exhaustion..  44. 2016
• Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans..  43. 2015
• Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A..  43. 2015
• A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner..  43. 2015
• OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response..  42. 2015
• A dendritic-cell-stromal axis maintains immune responses in lymph nodes..  42. 2015
• The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus..  42. 2014
• Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation..  40. 2014
• Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers..  40. 2014
• Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers..  40. 2014
• The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells..  40. 2014
• Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation..  39. 2013
• Autophagy regulates phagocytosis by modulating the expression of scavenger receptors..  39. 2013
• Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling..  39. 2013
• Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora..  39. 2013
• Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals..  39. 2013
• The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome..  39. 2013
• Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines..  38. 2013
• T cell factor 1 is required for group 2 innate lymphoid cell generation..  38. 2013
• Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells..  38. 2013
• Human CD1c+ dendritic cells drive the differentiation of CD103+ CD8+ mucosal effector T cells via the cytokine TGF-β..  38. 2013
• Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease..  37. 2012
• Commensal bacteria calibrate the activation threshold of innate antiviral immunity..  37. 2012
• An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes..  36. 2012
• Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense..  36. 2012
• DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells..  34. 2011
• ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6..  34. 2011
• Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation..  34. 2011
• Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner..  34. 2011
• Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division..  34. 2011
• Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands..  34. 2011
• Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation..  34. 2011
• Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion..  34. 2011
• CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut..  34. 2010
• Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cells..  33. 2010
• Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster..  32. 2010
• Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins..  32. 2010
• Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo..  32. 2010
• A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection..  31. 2009
• Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein..  30. 2009
• IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor..  29. 2008
• Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways..  29. 2008
• A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus..  29. 2008
• Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces..  28. 2008
• Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76..  28. 2008
• Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1..  27. 2007
• Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL..  26. 2007
• FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin..  26. 2007
• Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors..  25. 2006
• Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor..  25. 2006
• IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins..  24. 2006
• Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses..  23. 2005
• A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation..  22. 2005
• Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells..  22. 2005
• Regulatory T cell lineage specification by the forkhead transcription factor foxp3..  22. 2005
• SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1..  21. 2004
• Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells..  21. 2004
• Cognition and immunity; antibody impairs memory..  21. 2004
• Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors..  21. 2004
• Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation..  20. 2004
• Notch 1 signaling regulates peripheral T cell activation..  20. 2004
• Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential..  19. 2003
• SLP-76 regulates Fcgamma receptor and integrin signaling in neutrophils..  19. 2003
• Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6..  19. 2003
• Contribution of Vh gene replacement to the primary B cell repertoire..  19. 2003
• Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity..  19. 2003
• AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation..  18. 2003
• GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells..  18. 2003
• CDK inhibitor p18(INK4c) is required for the generation of functional plasma cells..  17. 2002
• Redundant and alternative roles for activating Fc receptors and complement in an antibody-dependent model of autoimmune vitiligo..  16. 2002
• DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection..  16. 2002
• Differential requirement for SLP-76 domains in T cell development and function..  15. 2001
• Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength..  14. 2001
• FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2..  12. 2000
• SHIP recruitment attenuates Fc gamma RIIB-induced B cell apoptosis..  10. 1999
• Ikaros sets thresholds for T cell activation and regulates chromosome propagation..  10. 1999
• Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice..  10. 1999
• Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase..  10. 1999
• CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav..  8. 1998
• SHIP modulates immune receptor responses by regulating membrane association of Btk..  8. 1998
• Altered antigen presentation in mice lacking H2-O..  8. 1998
• Reversal of EBV immortalization precedes apoptosis in IL-6-induced human B cell terminal differentiation..  7. 1997
• Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides..  7. 1997
• Counterregulation by the coreceptors CD19 and CD22 of MAP kinase activation by membrane immunoglobulin..  7. 1997
• Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6..  6. 1997
• Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation..  4. 1996
• FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway..  2. 1995
• Intracellular assembly and transport of endogenous peptide-MHC class II complexes..  1. 1994
• CD14 is a pattern recognition receptor..  1. 1994
• SnapShot: innate lymphoid cells..  39. 2013
• Not immune to stress: LBP's link to depression. 2023
• Mouse Watch: A Cautionary Tale. 2019
• A narrow circle of mutual friends. 2011
• Neuro-immune Interactions in the Tissues. 2020
• Gut Mycobiota in Immunity and Inflammatory Disease. 2019
• Targeting T Cell Co-receptors for Cancer Therapy. 2016
• Caspases Connect Cell-Death Signaling to Organismal Homeostasis. 2016
• Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair. 2015
• Autophagy and cellular immune responses. 2013
• Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. 2013
• Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease. 2012
• Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases. 2009
• Type I interferon in systemic lupus erythematosus and other autoimmune diseases. 2006
• Autoimmunity through cytokine-induced dendritic cell activation. 2004
• T cell death and transplantation tolerance. 2001
• Nutritional regulation of microbiota-derived metabolites: Implications for immunity and inflammation. 2024
• Principles of regulatory T cell function. 2023
• SARS-CoV-2 in immunocompromised individuals. 2022
• Nonresolving inflammation redux. 2022
• Control of immunity via nutritional interventions. 2022
• Control of regulatory T cell lineage commitment and maintenance. 2009

Identity

ISO Abbreviation

• Immunity

Linking ISSN

• 1074-7613

International Standard Serial Number (ISSN)

• 1074-7613

Electronic International Standard Serial Number (EISSN)

• 1097-4180