Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine. Academic Article uri icon

Overview

abstract

  • Vertebrate DNA is subjected to epigenetic base modifications that have been thought to be limited to methylated and other modified forms of cytidine. A recent study shows that methylation of adenine to form N (6)-methyladenine is a rare but readily detectable modification that can be mapped to distinct genomic sites in vertebrates.

publication date

  • January 13, 2016

Research

keywords

  • DNA
  • DNA Methylation
  • Epigenesis, Genetic
  • Genetic Variation

Identity

PubMed Central ID

  • PMC4712593

Scopus Document Identifier

  • 84954182421

Digital Object Identifier (DOI)

  • 10.1186/s13059-016-0874-7

PubMed ID

  • 26762117

Additional Document Info

volume

  • 17