Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine.
Academic Article
Overview
abstract
Vertebrate DNA is subjected to epigenetic base modifications that have been thought to be limited to methylated and other modified forms of cytidine. A recent study shows that methylation of adenine to form N (6)-methyladenine is a rare but readily detectable modification that can be mapped to distinct genomic sites in vertebrates.