New Roles for an Ancient Factor. Article uri icon

Overview

abstract

  • In 1996, Hyejin Kang and Erin Schuman, in search of new functions for the secreted growth factor brain-derived neurotrophic factor (BDNF), identified the protein synthesis requirement of BDNF in regulating synaptic plasticity. This landmark paper identified one of the first tractable pathways in the quest to dissect the complex process of synaptic remodeling and revealed the critical role for this neurotrophin in regulating long-term memory.

publication date

  • September 12, 2018

Research

keywords

  • Brain-Derived Neurotrophic Factor
  • Neuronal Plasticity
  • Synapses
  • Synaptic Transmission

Identity

Scopus Document Identifier

  • 85053132890

Digital Object Identifier (DOI)

  • 10.1016/j.tins.2018.08.012

PubMed ID

  • 30219601

Additional Document Info

volume

  • 41

issue

  • 11