Immunochemical detection of cytochrome P450C-M/F and NADPH-cytochrome P450 reductase in rat liver and kidney. Academic Article uri icon

Overview

abstract

  • The localization and distribution of NADPH-cytochrome P450 reductase and cytochrome P450C-M/F were investigated immunohistochemically in the liver and the kidney of untreated rats employing both an unlabelled antibody peroxidase-antiperoxidase method and a peroxidase labelled primary antibody technique. In both immunohistochemical procedures, the reductase and P450C-M/F were detected in hepatocytes throughout the liver. In contrast, the reductase and P450C-M/F in the kidney were only detectable in the proximal tubule cells.

publication date

  • February 15, 1988

Research

keywords

  • Cytochrome P-450 Enzyme System
  • Kidney
  • Liver
  • NADPH-Ferrihemoprotein Reductase

Identity

Scopus Document Identifier

  • 0023857407

PubMed ID

  • 3124846

Additional Document Info

volume

  • 150

issue

  • 3