Kappas, Attallah

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Ablation of adipose-HO-1 expression increases white fat over beige fat through inhibition of mitochondrial fusion and of PGC1α in female mice. Hormone molecular biology and clinical investigation. 2017 Academic Article GET IT
Times cited: 17
Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice. Journal of nutrition and metabolism. 2016 Academic Article GET IT
Times cited: 33
Epoxyeicosatrienoic Acids Regulate Adipocyte Differentiation of Mouse 3T3 Cells, Via PGC-1α Activation, Which Is Required for HO-1 Expression and Increased Mitochondrial Function. Stem cells and development. 2016 Academic Article GET IT
Times cited: 68
Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21. Obesity (Silver Spring, Md.). 2013 Academic Article GET IT
Times cited: 90
HO-1 induction improves the type-1 cardiorenal syndrome in mice with impaired angiotensin II-induced lymphocyte activation. Hypertension (Dallas, Tex. : 1979). 2013 Academic Article GET IT
Times cited: 16
Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet. Hypertension (Dallas, Tex. : 1979). 2012 Academic Article GET IT
Apo A1 Mimetic Rescues the Diabetic Phenotype of HO-2 Knockout Mice via an Increase in HO-1 Adiponectin and LKBI Signaling Pathway. International journal of hypertension. 2012 Academic Article GET IT
Times cited: 14
Heme oxygenase (HO-1) rescue of adipocyte dysfunction in HO-2 deficient mice via recruitment of epoxyeicosatrienoic acids (EETs) and adiponectin. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2012 Academic Article GET IT
Times cited: 42
Mechanism of heme-heme oxygenase system impairment of endothelium contraction in the spontaneously hypertensive rat. Hypertension (Dallas, Tex. : 1979). 2011 Editorial Article GET IT
Times cited: 5
Lentiviral-human heme oxygenase targeting endothelium improved vascular function in angiotensin II animal model of hypertension. Human gene therapy. 2011 Academic Article GET IT
Times cited: 51
Adipocyte heme oxygenase-1 induction attenuates metabolic syndrome in both male and female obese mice. Hypertension (Dallas, Tex. : 1979). 2010 Academic Article GET IT
Times cited: 101
Naive human T cells are activated and proliferate in response to the heme oxygenase-1 inhibitor tin mesoporphyrin. Journal of immunology (Baltimore, Md. : 1950). 2010 Academic Article GET IT
Times cited: 30
HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage. Bone. 2009 Academic Article GET IT
Times cited: 110
Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats. Hypertension (Dallas, Tex. : 1979). 2009 Academic Article GET IT
Times cited: 158
Pharmacological and clinical aspects of heme oxygenase. Pharmacological reviews. 2008 Information Resource GET IT
Times cited: 860
Interdiction of the diabetic state in NOD mice by sustained induction of heme oxygenase: possible role of carbon monoxide and bilirubin. Antioxidants & redox signaling. 2007 Academic Article GET IT
Times cited: 44
Long-lasting expression of HO-1 delays progression of type I diabetes in NOD mice. Cell cycle (Georgetown, Tex.). 2007 Academic Article GET IT
Times cited: 44
Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects. The Journal of pharmacology and experimental therapeutics. 2006 Academic Article GET IT
Times cited: 101
Heme oxygenase and the cardiovascular-renal system. Free radical biology & medicine. 2005 Information Resource GET IT
Times cited: 306
Circulating endothelial cells are elevated in patients with type 2 diabetes mellitus independently of HbA(1)c. Diabetologia. 2005 Academic Article GET IT
Times cited: 97
Chemoprevention of severe neonatal hyperbilirubinemia. Seminars in perinatology. 2004 Information Resource GET IT
Overexpression of human heme oxygenase-1 attenuates endothelial cell sloughing in experimental diabetes. American journal of physiology. Heart and circulatory physiology. 2004 Academic Article GET IT
Times cited: 94
Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 238
Human heme oxygenase: cell cycle-dependent expression and DNA microarray identification of multiple gene responses after transduction of endothelial cells. Journal of cellular biochemistry. 2003 Academic Article GET IT
Times cited: 45
Protective effect of HO-1 against oxidative stress in human hepatoma cell line (HepG2) is independent of telomerase enzyme activity. The international journal of biochemistry & cell biology. 2002 Academic Article GET IT
Times cited: 53
Significance of heme oxygenase in prolactin-mediated cell proliferation and angiogenesis in human endothelial cells. International journal of molecular medicine. 2002 Academic Article GET IT
Times cited: 53
Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression. Biochemical and biophysical research communications. 2002 Academic Article GET IT
Times cited: 77
A significant role for the heme oxygenase-1 gene in endothelial cell cycle progression. Biochemical and biophysical research communications. 2002 Academic Article GET IT
Times cited: 50
Regulation of cyclooxygenase by the heme-heme oxygenase system in microvessel endothelial cells. The Journal of pharmacology and experimental therapeutics. 2002 Academic Article GET IT
Times cited: 96
Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs. Proceedings of the National Academy of Sciences of the United States of America. 2001 Academic Article GET IT
Times cited: 52
Human heme oxygenase-1 gene transfer lowers blood pressure and promotes growth in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 2001 Academic Article GET IT
Times cited: 132
A single dose of Sn-mesoporphyrin prevents development of severe hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns. Pediatrics. 2001 Academic Article GET IT
Times cited: 63
Adenoviral vector-mediated transfer of human heme oxygenase in rats decreases renal heme-dependent arachidonic acid epoxygenase activity. The Journal of pharmacology and experimental therapeutics. 2000 Academic Article GET IT
Times cited: 31
Molecular aspects of the inherited porphyrias. Journal of internal medicine. 2000 Information Resource GET IT
Times cited: 69
Negative regulation of human heme oxygenase in microvessel endothelial cells by dexamethasone. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1999 Academic Article GET IT
Times cited: 40
Differential effects of heme oxygenase isoforms on heme mediation of endothelial intracellular adhesion molecule 1 expression. The Journal of pharmacology and experimental therapeutics. 1999 Academic Article GET IT
Times cited: 136
Heme oxygenase inhibitors transiently increase serum ferritin concentrations without altering other acute-phase reactants in man. Pharmacology. 1999 Academic Article GET IT
Times cited: 10
Pharmacologic effects of the red blood cell substitutes cross-linked and non-cross-linked hemoglobins on hematopoiesis in rabbits. Pharmacology. 1999 Academic Article GET IT
Times cited: 3
Comparative pharmacology of zinc mesoporphyrin and tin mesoporphyrin: toxic actions of zinc mesoporphyrin on hematopoiesis and progenitor cell mobilization. Pharmacology. 1999 Academic Article GET IT
Times cited: 12
Control of severe hyperbilirubinemia in full-term newborns with the inhibitor of bilirubin production Sn-mesoporphyrin. Pediatrics. 1999 Academic Article GET IT
Times cited: 75
Control of hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns using an inhibitor of bilirubin production, Sn-mesoporphyrin. Pediatrics. 1998 Academic Article GET IT
Times cited: 47
Sn-mesoporphyrin suppression of hyperbilirubinemia in EHBR/Eis rats, an animal model of Dubin-Johnson syndrome. Pharmacology. 1998 Academic Article GET IT
Times cited: 5
Heme oxygenase induction with attenuation of experimentally induced corneal inflammation. Biochemical pharmacology. 1997 Academic Article GET IT
Times cited: 73
Zinc porphyrins: potent inhibitors of hematopoieses in animal and human bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 1997 Academic Article GET IT
Times cited: 53
Effects of a series of metalloporphyrins on adrenal, testicular and thyroid function in rats. Pharmacology. 1996 Academic Article GET IT
Times cited: 4
Tissue distribution of synthetic heme analogues: studies with tin, chromium, and zinc mesoporphyrins. Pharmacology. 1996 Academic Article GET IT
Times cited: 11
Inhibition of human immunodeficiency virus-1 reverse transcriptase by heme and synthetic heme analogs. Proceedings of the Association of American Physicians. 1996 Academic Article GET IT
Times cited: 24
Adenovirus-mediated heme oxygenase-1 gene transfer into rabbit ocular tissues. Investigative ophthalmology & visual science. 1995 Academic Article GET IT
Times cited: 99
Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity. Proceedings of the National Academy of Sciences of the United States of America. 1995 Academic Article GET IT
Times cited: 319
Direct comparison of Sn-mesoporphyrin, an inhibitor of bilirubin production, and phototherapy in controlling hyperbilirubinemia in term and near-term newborns. Pediatrics. 1995 Academic Article GET IT
Times cited: 76
Differential heme oxygenase induction by stannous and stannic ions in the heart. Journal of cellular biochemistry. 1995 Academic Article GET IT
Times cited: 15
The comparative abilities of inorganic cobalt and cobalt-protoporphyrin to affect copper metabolism and elevate plasma ceruloplasmin. Pharmacology. 1995 Academic Article GET IT
Times cited: 7
Modulation of corneal heme oxygenase expression by oxidative stress agents. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 1995 Academic Article GET IT
Times cited: 27
Distribution of metalloporphyrin inhibitors of heme oxygenase among serum transport proteins. Pharmacology. 1994 Academic Article GET IT
Times cited: 3
Incorporation of metalloporphyrin inhibitors of heme oxygenase into micelles and liposomes. Pharmacology. 1994 Academic Article GET IT
Times cited: 2
Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene. Proceedings of the National Academy of Sciences of the United States of America. 1994 Academic Article GET IT
Times cited: 368
Characterization of a 142-bp fragment of the murine c-fos oncogene promoter upstream of the SIF-binding element. Gene. 1994 Academic Article GET IT
Times cited: 10
Control of jaundice in preterm newborns by an inhibitor of bilirubin production: studies with tin-mesoporphyrin. Pediatrics. 1994 Academic Article GET IT
Times cited: 121
Additive effect of erythropoietin and heme on murine hematopoietic recovery after azidothymidine treatment. Blood. 1993 Academic Article GET IT
Times cited: 14
Synergistic effect of heme and IL-1 on hematopoietic stromal regeneration after radiation. American journal of hematology. 1993 Academic Article GET IT
Times cited: 9
Tin-mesoporphyrin inhibits heme oxygenase activity and heme-iron absorption in the intestine. Pharmacology. 1993 Academic Article GET IT
Times cited: 22
Investigations on the role of hemopexin and albumin in plasma clearance and tissue distribution of Sn-protoporphyrin. The Journal of laboratory and clinical medicine. 1993 Academic Article GET IT
Times cited: 1
Coexpression of erythropoietin and heme oxygenase genes in Hep3B cells. Hepatology (Baltimore, Md.). 1993 Academic Article GET IT
Times cited: 6
Elevated levels of heme oxygenase-1 activity and mRNA in peripheral blood adherent cells of acquired immunodeficiency syndrome patients. American journal of hematology. 1993 Academic Article GET IT
Times cited: 25
Targeted delivery of a heme oxygenase inhibitor with a lyophilized liposomal tin mesoporphyrin formulation. Pharmaceutical research. 1993 Academic Article GET IT
Times cited: 11
Comparative effects of heme and metalloporphyrins on interferon-gamma-mediated pathways in monocytic cells (THP-1). Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1993 Academic Article GET IT
Times cited: 15
The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cells. The Biochemical journal. 1993 Academic Article GET IT
Times cited: 51
Long-term bone marrow stromal and hemopoietic toxicity to AZT: protective role of heme and IL-1. Experimental hematology. 1993 Academic Article GET IT
Times cited: 23
Photodynamic properties of Sn-protoporphyrin: clinical investigations and phototesting in human subjects. Acta dermato-venereologica. 1993 Academic Article GET IT
Times cited: 6
Hypothalamic mechanism for cobalt protoporphyrin-induced hypophagia and weight loss: inhibition of the feeding response to NPY. Brain research. Molecular brain research. 1992 Academic Article GET IT
Times cited: 14
Injection of cobalt protoporphyrin into the medial nuclei of the hypothalamus elicits weight loss. The American journal of physiology. 1992 Academic Article GET IT
Times cited: 14
Interleukin-6 down regulates the expression of transcripts encoding cytochrome P450 IA1, IA2 and IIIA3 in human hepatoma cells. Biochemical and biophysical research communications. 1992 Academic Article GET IT
Times cited: 90
Intestinal heme oxygenase inhibition and increased biliary iron excretion by metalloporphyrins. Gastroenterology. 1992 Academic Article GET IT
Times cited: 21
Heme oxygenase is a positive acute-phase reactant in human Hep3B hepatoma cells. Blood. 1992 Academic Article GET IT
Times cited: 73
Intracerebroventricular administration of cobalt protoporphyrin elicits prolonged weight reduction in rats. The American journal of physiology. 1991 Academic Article GET IT
Times cited: 15
Regulation of food intake and body weight in rats by the synthetic heme analogue cobalt protoporphyrin. The American journal of physiology. 1991 Academic Article GET IT
Times cited: 22
Effects of protein and carbohydrate content of diet on drug conjugation. Clinical pharmacology and therapeutics. 1991 Academic Article GET IT
Times cited: 24
A heat-inducible nuclear factor that binds to the heat-shock element of the human haem oxygenase gene. The Biochemical journal. 1991 Academic Article GET IT
Times cited: 23
Comparative photoactivity of tin and zinc porphyrin inhibitors of heme oxygenase: pronounced photolability of the zinc compounds. Photochemistry and photobiology. 1991 Academic Article GET IT
Times cited: 25
Tin(Sn+4)-diiododeuteroporphyrin; an in vitro and in vivo inhibitor of heme oxygenase with substantially reduced photoactive properties. The Journal of pharmacology and experimental therapeutics. 1991 Academic Article GET IT
Times cited: 7
Diet and cimetidine induce comparable changes in theophylline metabolism in normal subjects. Hepatology (Baltimore, Md.). 1991 Academic Article GET IT
Times cited: 20
Induction of heme oxygenase in the small intestinal epithelium: a response to oral cadmium exposure. Toxicology. 1991 Academic Article GET IT
Times cited: 20
Hereditary hepatic porphyria due to homozygous delta-aminolevulinic acid dehydratase deficiency: studies in lymphocytes and erythrocytes. European journal of clinical investigation. 1991 Academic Article GET IT
Times cited: 14
Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine. Proceedings of the National Academy of Sciences of the United States of America. 1991 Academic Article GET IT
Times cited: 56
Cobalt protoporphyrin regulates body weight in beagle dogs: induction of weight loss in normal animals of stable adult weight. Pharmacology. 1991 Academic Article GET IT
Times cited: 11
Dietary regulation of cytochrome P450. Annual review of nutrition. 1991 Information Resource GET IT
Times cited: 64
A fluorometric method for measuring ethoxycoumarin O-deethylase activity by reversed-phase high performance liquid chromatography. Analytical biochemistry. 1990 Academic Article GET IT
Times cited: 13
Message amplification phenotyping of an inherited delta-aminolevulinate dehydratase deficiency in a family with acute hepatic porphyria. Biochemical and biophysical research communications. 1990 Academic Article GET IT
Times cited: 18
Studies with the haeme oxygenase inhibitor Sn-protoporphyrin in patients with primary biliary cirrhosis and idiopathic haemochromatosis. Gut. 1990 Academic Article GET IT
Times cited: 21
Activation of heme oxygenase and heat shock protein 70 genes by stress in human hepatoma cells. Biochemical and biophysical research communications. 1990 Academic Article GET IT
Times cited: 35
Cobalt-protoporphyrin suppresses expression of genetic obesity in homozygous (fa/fa) Zucker rats. Pharmacology. 1990 Academic Article GET IT
Times cited: 17
On the validation of the system of Aspergillus for testing environmental aneugens. Progress in clinical and biological research. 1990 Academic Article GET IT
Times cited: 2
Protective effect of Sn-protoporphyrin against doxorubicin-induced perturbations of heme metabolism. Life sciences. 1990 Academic Article GET IT
Times cited: 6
Targeting of heme oxygenase inhibitors to the spleen markedly increases their ability to diminish bilirubin production. Pediatrics. 1989 Academic Article GET IT
Times cited: 15
Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells. Biochemical and biophysical research communications. 1989 Academic Article GET IT
Times cited: 53
Characterization of heme oxygenase in the small intestinal epithelium. Archives of biochemistry and biophysics. 1989 Academic Article GET IT
Times cited: 32
Regulation of food intake and body weight by cobalt porphyrins in animals. Proceedings of the National Academy of Sciences of the United States of America. 1989 Academic Article GET IT
Times cited: 46
delta-Aminolaevulinate synthase in human HepG2 hepatoma cells. Repression by haemin and induction by chemicals. The Biochemical journal. 1989 Academic Article GET IT
Times cited: 36
Erythrocyte uroporphyrinogen decarboxylase activity in porphyria cutanea tarda: a study of 40 consecutive patients. The Journal of investigative dermatology. 1989 Academic Article GET IT
Times cited: 37
Trace metal interactions in vivo: inorganic cobalt enhances urinary copper excretion without producing an associated zincuresis in rats. The Journal of nutrition. 1989 Academic Article GET IT
Times cited: 16
Lack of effect of pregnancy or hematin therapy on erythrocyte porphobilinogen deaminase activity in acute intermittent porphyria. The New England journal of medicine. 1989 Article GET IT
Times cited: 3
Tin-protoporphyrin and long wave length ultraviolet light in treatment of psoriasis. Lancet (London, England). 1989 Academic Article GET IT
Times cited: 26
Pharmacokinetics of tin-mesoporphyrin in man and the effects of tin-chelated porphyrins on hyperexcretion of heme pathway precursors in patients with acute inducible porphyria. Hepatology (Baltimore, Md.). 1989 Academic Article GET IT
Times cited: 38
The effects of acute-phase inducers and dimethyl sulphoxide on delta-aminolaevulinate synthase activity in human HepG2 hepatoma cells. The Biochemical journal. 1989 Academic Article GET IT
Times cited: 13
Actions of orally administered organotin compounds on heme metabolism and cytochrome P-450 content and function in intestinal epithelium. Biochemical pharmacology. 1989 Academic Article GET IT
Times cited: 20
Comparative ability of exogenously administered metals to alter tissue levels and urinary output of copper and zinc. Pharmacology. 1989 Academic Article GET IT
Times cited: 4
Effects of tin-porphyrins on developmental changes in hepatic cytochrome P450 content, selected P450-dependent drug-metabolizing enzyme activities and brain glutathione levels in the newborn rat. Pharmacology. 1989 Academic Article GET IT
Times cited: 10
On the mechanisms of induced aneuploidy in Aspergillus nidulans and validation of tests for genomic mutations. Progress in clinical and biological research. 1989 Academic Article GET IT
Times cited: 10
The in vitro and in vivo inhibition of intestinal heme oxygenase by tin-protoporphyrin. Pharmacology. 1989 Academic Article GET IT
Times cited: 18
Sn-protoporphyrin lowers serum bilirubin levels, decreases biliary bilirubin output, enhances biliary heme excretion and potently inhibits hepatic heme oxygenase activity in normal human subjects. Hepatology (Baltimore, Md.). 1988 Academic Article GET IT
Times cited: 41
Photophysical properties of Sn-porphyrins: potential clinical implications. Pediatrics. 1988 Academic Article GET IT
Times cited: 31
Sn-protoporphyrin use in the management of hyperbilirubinemia in term newborns with direct Coombs-positive ABO incompatibility. Pediatrics. 1988 Academic Article GET IT
Times cited: 143
Sn-protoporphyrin blocks the increase in serum bilirubin levels that develops postnatally in homozygous Gunn rats. The Journal of experimental medicine. 1988 Academic Article GET IT
Times cited: 12
Immunochemical detection of cytochrome P450C-M/F and NADPH-cytochrome P450 reductase in rat liver and kidney. Biochemical and biophysical research communications. 1988 Academic Article GET IT
Times cited: 4
Tin-protoporphyrin inhibits heme oxygenase and prevents the decline in hepatic heme and cytochrome P-450 contents produced in nude mice by tumor transplantation. Biochemical and biophysical research communications. 1988 Academic Article GET IT
Times cited: 4
Cytochrome P-450C-M/F, a new constitutive form of microsomal cytochrome P-450 in male and female rat liver with estrogen 2- and 16 alpha-hydroxylase activity. Biochemistry. 1988 Academic Article GET IT
Times cited: 24
Partial purification of cytochrome P450 from rat brain and demonstration of estradiol hydroxylation. Biochemical and biophysical research communications. 1987 Academic Article GET IT
Times cited: 27
Reduction of the C2 and C4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism. Archives of biochemistry and biophysics. 1987 Academic Article GET IT
Times cited: 85
Diet-hormone interactions: protein/carbohydrate ratio alters reciprocally the plasma levels of testosterone and cortisol and their respective binding globulins in man. Life sciences. 1987 Academic Article GET IT
Times cited: 126
Porphyria cutanea tarda associated with the acquired immune deficiency syndrome. American journal of hematology. 1987 Academic Article GET IT
Times cited: 83
A comparison of the utility of Dowex resin and polybenzimidazole Aurorez resin in the determination of urinary porphobilinogen concentrations. Clinica chimica acta; international journal of clinical chemistry. 1987 Academic Article GET IT
Times cited: 2
Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver. Proceedings of the National Academy of Sciences of the United States of America. 1987 Academic Article GET IT
Times cited: 161
Proof that Sn-protoporphyrin inhibits the enzymatic catabolism of heme in vivo. Suppression of 14CO generation from radiolabeled endogenous and exogenous heme sources. The Journal of experimental medicine. 1987 Academic Article GET IT
Times cited: 18
Drug metabolism by the human hepatoma cell, Hep G2. Biochemical and biophysical research communications. 1987 Academic Article GET IT
Times cited: 159
Cobalt-protoporphyrin suppresses thyroid and testicular hormone concentrations in rat serum: a novel action of this synthetic heme analogue. Pharmacology. 1987 Academic Article GET IT
Times cited: 25
Relationship of suppression of the androgenic axis by cobalt-protoporphyrin to its effects on weight loss and hepatic heme oxygenase induction. Pharmacology. 1987 Academic Article GET IT
Times cited: 17
Chloro-substituent sites and probability of co-planarity in polychlorinated biphenyls in determining uroporphyrin formation in cultured liver cells. The Biochemical journal. 1986 Article GET IT
Induction of haem synthesis in Hep G2 human hepatoma cells by dimethyl sulphoxide. A transcriptionally activated event. The Biochemical journal. 1986 Academic Article GET IT
Times cited: 18
Disposition of tin-protoporphyrin and suppression of hyperbilirubinemia in humans. Clinical pharmacology and therapeutics. 1986 Academic Article GET IT
Times cited: 49
Studies of the influence of chloro-substituent sites and conformational energy in polychlorinated biphenyls on uroporphyrin formation in chick-embryo liver cell cultures. The Biochemical journal. 1986 Academic Article GET IT
Biochemical properties of the heme oxygenase inhibitor, Sn-protoporphyrin. Interactions with apomyoglobin and human serum albumin. The Journal of biological chemistry. 1986 Academic Article GET IT
Times cited: 34
Sn-protoporphyrin inhibition of fetal and neonatal brain heme oxygenase. Transplacental passage of the metalloporphyrin and prenatal suppression of hyperbilirubinemia in the newborn animal. The Journal of clinical investigation. 1986 Academic Article GET IT
Times cited: 53
Control of heme metabolism with synthetic metalloporphyrins. The Journal of clinical investigation. 1986 Information Resource GET IT
Times cited: 134
Ethnic differences in reactions to drugs and xenobiotics. Nutrition as an environmental influence on chemical metabolism in man. Progress in clinical and biological research. 1986 Information Resource GET IT
Times cited: 9
Sn-protoporphyrin suppresses chemically induced experimental hepatic porphyria. Potential clinical implications. The Journal of clinical investigation. 1985 Academic Article GET IT
Times cited: 18
Heme binding to murine erythroleukemia cells. Evidence for a heme receptor. The Journal of biological chemistry. 1985 Academic Article GET IT
Times cited: 53
Hereditary tyrosinemia. Formation of succinylacetone-amino acid adducts. The Journal of experimental medicine. 1985 Academic Article GET IT
Times cited: 40
Long-term administration of massive doses of Sn-protoporphyrin in anemic mutant mice (sphha/sphha). The Journal of experimental medicine. 1985 Academic Article GET IT
Times cited: 23
Hormonal regulation of heme oxygenase induction in avian hepatocyte culture. Biochemical pharmacology. 1985 Academic Article GET IT
Times cited: 23
Altered induction response of hepatic cytochrome P-450 to phenobarbital, 3-methylcholanthrene, and beta-naphthoflavone in organotin-treated animals. Biochemical pharmacology. 1985 Academic Article GET IT
Times cited: 19
Studies on the mechanism of Sn-protoporphyrin suppression of hyperbilirubinemia. Inhibition of heme oxidation and bilirubin production. The Journal of clinical investigation. 1985 Academic Article GET IT
Times cited: 41
The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin. Proceedings of the National Academy of Sciences of the United States of America. 1985 Academic Article GET IT
Times cited: 64
Interindividual differences in the metabolism of xenobiotics. Carcinogenesis; a comprehensive survey. 1985 Information Resource GET IT
Times cited: 6
Nutrient regulation of chemical metabolism in humans. Federation proceedings. 1985 Information Resource GET IT
Times cited: 16
Sn-protoporphyrin rapidly and markedly enhances the heme saturation of hepatic tryptophan pyrrolase. Evidence that this synthetic metalloporphyrin increases the functional content of heme in the liver. The Journal of clinical investigation. 1985 Academic Article GET IT
Times cited: 18
Fluorometric measurement of tin-protoporphyrin in biological samples. Analytical biochemistry. 1984 Academic Article GET IT
Times cited: 13
Control of heme and cytochrome P-450 metabolism by inorganic metals, organometals and synthetic metalloporphyrins. Environmental health perspectives. 1984 Academic Article GET IT
Times cited: 36
Porphyrin-heme biosynthesis in organotypic cultures of mouse dorsal root ganglia. Effects of heme and lead on porphyrin synthesis and peripheral myelin. The Journal of clinical investigation. 1984 Academic Article GET IT
Times cited: 24
An experimental model of postnatal jaundice in the suckling rat. Suppression of induced hyperbilirubinemia by Sn-protoporphyrin. The Journal of clinical investigation. 1984 Academic Article GET IT
Times cited: 30
The influence of dietary protein and carbohydrate on the principal oxidative biotransformations of estradiol in normal subjects. The Journal of clinical endocrinology and metabolism. 1984 Academic Article GET IT
Times cited: 99
The potent induction of intestinal heme oxygenase by the organotin compound, bis(tri-n-butyltin)oxide. Biochemical and biophysical research communications. 1984 Academic Article GET IT
Times cited: 19
Control of heme oxygenase and plasma levels of bilirubin by a synthetic heme analogue, tin-protoporphyrin. Hepatology (Baltimore, Md.). 1984 Academic Article GET IT
Times cited: 67
Effect of brussels sprouts and cabbage on drug conjugation. Clinical pharmacology and therapeutics. 1984 Academic Article GET IT
Times cited: 109
Tissue distribution and disposition of tin-protoporphyrin, a potent competitive inhibitor of heme oxygenase. The Journal of pharmacology and experimental therapeutics. 1984 Academic Article GET IT
Times cited: 88
Nutrition-endocrine interactions: induction of reciprocal changes in the delta 4-5 alpha-reduction of testosterone and the cytochrome P-450-dependent oxidation of estradiol by dietary macronutrients in man. Proceedings of the National Academy of Sciences of the United States of America. 1983 Academic Article GET IT
Metabolism of estradiol in liver cell culture. Differential responses of C-2 and C-16 oxidations to drugs and other chemicals that induce selective species of cytochrome P-450. The Journal of clinical investigation. 1983 Academic Article GET IT
Times cited: 15
Acetaminophen metabolism in subjects fed charcoal-broiled beef. Clinical pharmacology and therapeutics. 1983 Academic Article GET IT
Times cited: 27
Growth-promoting effects of iron- and cobalt- protoporphyrins on cultured embryonic cells. Journal of cellular physiology. 1983 Academic Article GET IT
Times cited: 16
Effects of polychlorinated biphenyl compounds, 2,3,7,8-tetrachlorodibenzo-p-dioxin, phenobarbital and iron on hepatic uroporphyrinogen decarboxylase. Implications for the pathogenesis of porphyria. The Biochemical journal. 1983 Academic Article GET IT
Times cited: 43
Tin-protoporphyrin suppression of hyperbilirubinemia in mutant mice with severe hemolytic anemia. Blood. 1983 Academic Article GET IT
Times cited: 37
Hereditary tyrosinemia and the heme biosynthetic pathway. Profound inhibition of delta-aminolevulinic acid dehydratase activity by succinylacetone. The Journal of clinical investigation. 1983 Academic Article GET IT
Times cited: 118
Purification and properties of uroporphyrinogen decarboxylase from human erythrocytes. A single enzyme catalyzing the four sequential decarboxylations of uroporphyrinogens I and III. The Journal of biological chemistry. 1983 Academic Article GET IT
Times cited: 106
Purification and properties of human erythrocyte uroporphyrinogen decarboxylase: immunological demonstration of the enzyme defect in porphyria cutanea tarda. Transactions of the Association of American Physicians. 1983 Academic Article GET IT
Times cited: 27
Suppression of hyperbilirubinemia in the rat neonate by chromium-protoporphyrin. Interactions of metalloporphyrins with microsomal heme oxygenase of human spleen. The Journal of experimental medicine. 1982 Academic Article GET IT
Times cited: 28
Thyroid hormone regulation of heme oxidation in the liver. Proceedings of the National Academy of Sciences of the United States of America. 1982 Academic Article GET IT
Times cited: 33
Chemoprevention of neonatal jaundice: potency of tin-protoporphyrin in an animal model. Science (New York, N.Y.). 1982 Academic Article GET IT
Times cited: 88
Induction of hepatic cytochrome P-450 by natural steroids: relationship to the induction of delta-aminolevulinate synthase and porphyrin accumulation in the avian embryo. Archives of biochemistry and biophysics. 1982 Academic Article GET IT
Times cited: 31
A comparative study of heme degradation by NADPH-cytochrome c reductase alone and by the complete heme oxygenase system. Distinctive aspects of heme degradation by NADPH-cytochrome c reductase. The Journal of biological chemistry. 1982 Academic Article GET IT
Times cited: 58
Purification and properties of bovine spleen heme oxygenase. Amino acid composition and sites of action of inhibitors of heme oxidation. The Journal of biological chemistry. 1982 Academic Article GET IT
Times cited: 119
The occurrence of molecular interactions among NADPH-cytochrome c reductase, heme oxygenase, and biliverdin reductase in heme degradation. The Journal of biological chemistry. 1982 Academic Article GET IT
Times cited: 48
The oxidative degradation of heme c by the microsomal heme oxygenase system. The Journal of biological chemistry. 1982 Academic Article GET IT
Times cited: 19
Metal ion-mediated regulation of heme oxygenase induction in cultured avian liver cells. The Journal of biological chemistry. 1982 Academic Article GET IT
Times cited: 36
Cigarette smoking and chlorpromazine disposition and actions. Clinical pharmacology and therapeutics. 1982 Academic Article GET IT
Times cited: 36
Studies in porphyria: functional evidence for a partial deficiency of ferrochelatase activity in mitogen-stimulated lymphocytes from patients with erythropoietic protoporphyria. The Journal of clinical investigation. 1982 Academic Article GET IT
The cytochrome P-450-depleted animal: an experimental model for in vivo studies in chemical biology. Proceedings of the National Academy of Sciences of the United States of America. 1982 Academic Article GET IT
Times cited: 75
Metal induction of haem oxygenase without concurrent degradation of cytochrome P-450. Protective effects of compound SKF 525A on the haem protein. The Biochemical journal. 1982 Academic Article GET IT
Times cited: 17
Succinylacetone inhibits delta-aminolevulinate dehydratase and potentiates the drug and steroid induction of delta-aminolevulinate synthase in liver. Transactions of the Association of American Physicians. 1982 Academic Article GET IT
Times cited: 16
The influence of organometals on heme metabolism. In vivo and in vitro studies with organotins. Molecular pharmacology. 1982 Academic Article GET IT
Times cited: 45
Acute intermittent porphyria. Annals of internal medicine. 1981 Article GET IT
Times cited: 1
Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation. Proceedings of the National Academy of Sciences of the United States of America. 1981 Academic Article GET IT
Times cited: 283
Differential responses to inducers of delta-aminolaevulinate synthase and haem oxygenase during pregnancy. The Biochemical journal. 1981 Academic Article GET IT
Times cited: 9
Potent heme-degrading action of antimony and antimony-containing parasiticidal agents. The Journal of experimental medicine. 1981 Academic Article GET IT
Times cited: 21
Genetic, metabolic, and biochemical aspects of the porphyrias. Advances in human genetics. 1981 Information Resource GET IT
Times cited: 50
The potent heme oxygenase inducing action of arsenic and parasiticidal arsenicals. Pharmacology. 1981 Academic Article GET IT
Adrenalectomy enhances the induction of heme oxygenase and the degradation of cytochrome P-450 in liver. The Journal of biological chemistry. 1980 Academic Article GET IT
Times cited: 19
Metal ion interactions in the control of haem oxygenase induction in liver and kidney. The Biochemical journal. 1980 Academic Article GET IT
Times cited: 30
Prolonged induction of hepatic haem oxygenase and decreases in cytochrome P-450 content by organotin compounds. The Biochemical journal. 1980 Academic Article GET IT
Times cited: 41
Radiometric analysis of biological oxidations in man: sex differences in estradiol metabolism. Proceedings of the National Academy of Sciences of the United States of America. 1980 Academic Article GET IT
Times cited: 99
Regulation of human drug metabolism by dietary factors. Ciba Foundation symposium. 1980 Academic Article GET IT
Times cited: 32
Study of differences of estradiol metabolism between men and women by means of in vivo radiometric analysis. Transactions of the Association of American Physicians. 1980 Academic Article GET IT
Times cited: 5
Steroid induction of delta-aminolevulinic acid synthase and porphyrins in liver. Structure-activity studies and the permissive effects of hormones on the induction process. The Journal of biological chemistry. 1979 Academic Article GET IT
Times cited: 36
Intraindividual variation in drug disposition. Clinical pharmacology and therapeutics. 1979 Academic Article GET IT
Times cited: 57
Manganese and zinc blockade of enzyme induction: studies with microsomal heme oxygenase. Proceedings of the National Academy of Sciences of the United States of America. 1979 Academic Article GET IT
Times cited: 20
Nutrition and oxidative drug metabolism in man: relative influence of dietary lipids, carbohydrate, and protein. Clinical pharmacology and therapeutics. 1979 Academic Article GET IT
Times cited: 79
Studies on porphyrin-heme biosynthesis in organotypic cultures of chick dorsal root ganglia. II. The effect of lead. Environmental research. 1979 Academic Article GET IT
Times cited: 7
The influence of steroid hormone metabolites on the in vitro development of erythroid colonies derived from human bone marrow. The Journal of experimental medicine. 1979 Academic Article GET IT
Times cited: 27
Studies in porphyria. VIII. Relationship of the 5 alpha-reductive metabolism of steroid hormones to clinical expression of the genetic defect in acute intermittent porphyria. The American journal of medicine. 1979 Academic Article GET IT
Times cited: 29
Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis. The Journal of biological chemistry. 1979 Academic Article GET IT
Times cited: 74
Stimulatory effect of brussels sprouts and cabbage on human drug metabolism. Clinical pharmacology and therapeutics. 1979 Academic Article GET IT
Times cited: 212
Studies in porphyria IX: Detection of the gene defect of erythropoietic protoporphyria in mitogen-stimulated human lymphocytes. Transactions of the Association of American Physicians. 1979 Academic Article GET IT
Times cited: 1
Human skin aryl hydrocarbon hydroxylase. Induction by coal tar. The Journal of clinical investigation. 1978 Academic Article GET IT
Times cited: 60
Studies on porphyrin-heme biosynthesis in organotypic cultures of chick dorsal root ganglion. I. Observations on neuronal and non-neuronal elements. Journal of neuropathology and experimental neurology. 1978 Academic Article GET IT
Times cited: 24
Lead hazard among ironworkers. Dismantling lead-painted elevated subway line in New York City. New York state journal of medicine. 1978 Academic Article GET IT
Times cited: 17
7,8-Benzoflavone stimulates the metabolic activation of aflatoxin B1 to mutagens by human liver. Biochemical and biophysical research communications. 1978 Academic Article GET IT
Times cited: 58
Prematurely evoked synthesis and induction of delta-aminolevulinate synthetase in neonatal liver. Evidence for metal ion repression of enzyme formation. The Journal of biological chemistry. 1978 Academic Article GET IT
Times cited: 38
Effect of charcoal-broiled beef on antipyrine and theophylline metabolism. Clinical pharmacology and therapeutics. 1978 Academic Article GET IT
Times cited: 115
Studies in porphyria. VII. Induction of uroporphyrinogen-I synthase and expression of the gene defect of acute intermittent porphyria in mitogen-stimulated human lymphocytes. The Journal of clinical investigation. 1978 Academic Article GET IT
Times cited: 45
Enzymes of heme metabolism in the kidney: regulation by trace metals which do not form heme complexes. The Journal of experimental medicine. 1977 Academic Article GET IT
Times cited: 15
Oxidative drug metabolism and inducibility by phenobarbital in sickle cell anemia. Clinical pharmacology and therapeutics. 1977 Academic Article GET IT
Times cited: 4
The inducing properties of polychlorinated biphenyls on hepatic monooxygenases. Clinical pharmacology and therapeutics. 1977 Academic Article GET IT
Times cited: 30
Lead intoxication among demolition workers: the effect of lead on the hepatic cytochrome P-450 system in humans. Journal of toxicology and environmental health. 1977 Academic Article GET IT
Times cited: 18
Heterogeneity of cytochrome P-450s induced by polychlorinated biphenyls. The Journal of biological chemistry. 1977 Academic Article GET IT
Times cited: 115
In memoriam: Sam Granick 1909-1977. Blood. 1977 Academic Article GET IT
Increased erythrocyte uroporphyrinogen-l-synthetase, delta-aminolevulinic acid dehydratase and protoporphyrin in hemolytic anemias. The American journal of medicine. 1977 Academic Article GET IT
Times cited: 43
Solubilization and partial purification of heme oxygenase from rat liver. The Journal of biological chemistry. 1977 Academic Article GET IT
Times cited: 60
Alterations in drug metabolism in workers exposed to polychlorinated biphenyls. Clinical pharmacology and therapeutics. 1977 Academic Article GET IT
Times cited: 51
On the occurrence of cytochrome P-450 and aryl hydrocarbon hydroxylase activity in rat brain. The Journal of experimental medicine. 1977 Academic Article GET IT
Times cited: 62
Regulation of heme pathway enzymes and cellular glutathione content by metals that do not chelate with tetrapyrroles: blockade of metal effects by thiols. Proceedings of the National Academy of Sciences of the United States of America. 1977 Academic Article GET IT
Times cited: 73
Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process. The Journal of biological chemistry. 1977 Academic Article GET IT
Times cited: 102
Regulation of drug metabolism in man by environmental chemicals and diet. Federation proceedings. 1977 Academic Article GET IT
Times cited: 66
Enzymatic oxidation of cobalt protoporphyrin IX: observations on the mechanism of heme oxygenase action. Biochemistry. 1977 Academic Article GET IT
Times cited: 54
Deficient induction of uroporphyrinogen-I synthase activity in mitogen-stimulated lymphocytes from patients with acute intermittent porphyria. Transactions of the Association of American Physicians. 1977 Academic Article GET IT
Times cited: 2
Induction of a deficiency of steroid delta 4-5 alpha-reductase activity in liver by a porphyrinogenic drug. The Journal of clinical investigation. 1977 Academic Article GET IT
Times cited: 17
Studies in porphyria. VI. Biosynthesis of porphyrins in mammalian skin and in the skin of porphyric patients. The Journal of investigative dermatology. 1977 Academic Article GET IT
Times cited: 18
Prenatal diagnosis of acute intermittent porphyria. The New England journal of medicine. 1976 Article GET IT
Times cited: 3
Effect of charcoal-broiled beef on phenacetin metabolism in man. Science (New York, N.Y.). 1976 Academic Article GET IT
Times cited: 38
Enhanced phenacetin metabolism in human subjects fed charcoal-broiled beef. Clinical pharmacology and therapeutics. 1976 Academic Article GET IT
Times cited: 120
Influence of dietary protein and carbohydrate on antipyrine and theophylline metabolism in man. Clinical pharmacology and therapeutics. 1976 Academic Article GET IT
Times cited: 217
Selenium regulation of hepatic heme metabolism: induction of delta-aminolevulinate synthase and heme oxygenase. Proceedings of the National Academy of Sciences of the United States of America. 1976 Academic Article GET IT
Times cited: 38
The effect of environmental light exposure on drug-induced porphyria in the rat. Photochemistry and photobiology. 1976 Academic Article GET IT
Interactions between nutritional factors and drug biotransformations in man. Proceedings of the National Academy of Sciences of the United States of America. 1976 Academic Article GET IT
Times cited: 83
Cobalt inhibition of synthesis and induction of delta-aminolevulinate synthase in liver. Proceedings of the National Academy of Sciences of the United States of America. 1976 Academic Article GET IT
Times cited: 27
Tin: a potent inducer of heme oxygenase in kidney. Science (New York, N.Y.). 1976 Academic Article GET IT
Times cited: 74
Lead intoxication: effects on cytochrome P-450-mediated hepatic oxidations. Clinical pharmacology and therapeutics. 1976 Academic Article GET IT
Times cited: 50
Inhibition of chemical induction of porphyrin synthesis in chick embryo liver cells by partially purified human chorionic gonadotropin. Biochemical and biophysical research communications. 1976 Academic Article GET IT
Studies on the mechanism of induction of haem oxygenase by cobalt and other metal ions. The Biochemical journal. 1976 Academic Article GET IT
Times cited: 162
Studies in porphyria. V. Drug oxidation rates in hereditary hepatic porphyria. Clinical pharmacology and therapeutics. 1976 Academic Article GET IT
Times cited: 33
The induction of heme oxidation in various tissues by trace metals: evidence for the catabolism of endogenous heme by hepatic heme oxygenase. Annals of clinical research. 1976 Academic Article GET IT
Times cited: 43
Sequential induction of enzymes in the heme biosynthetic pathway during erythroid differentiation. Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society. 1975 Academic Article GET IT
Times cited: 6
Studies in porphyria. IV. Expression of the gene defect of acute intermittent porphyria in cultured human skin fibroblasts and amniotic cells: prenatal diagnosis of the porphyric trait. The Journal of experimental medicine. 1975 Academic Article GET IT
Times cited: 49
Cobalt stimulation of heme degradation in the liver. Dissociation of microsomal oxidation of heme from cytochrome P-450. The Journal of biological chemistry. 1975 Academic Article GET IT
Times cited: 165
How the liver metabolizes foreign substances. Scientific American. 1975 Academic Article GET IT
Times cited: 30
Study of the developmental pattern of heme catabolism in liver and the effects of cobalt on cytochrome P-450 and the rate of heme oxidation during the neonatal period. The Journal of experimental medicine. 1975 Academic Article GET IT
Times cited: 35
Exacerbation of hereditary hepatic porphyria by surreptitious ingestion of an unusual provacative agent--a mouthwash preparation. The New England journal of medicine. 1975 Academic Article GET IT
Times cited: 10
Effect of lead and genetic factors on heme biosynthesis in the human red cell. Annals of the New York Academy of Sciences. 1975 Academic Article GET IT
Times cited: 57
Microscope immersion oils: effects of skin application on cutaneous and hepatic drug-metabolizing enzymes. Biochemical pharmacology. 1975 Academic Article GET IT
Times cited: 24
The degradative effects of porphyrins and heme compounds on components of the microsomal mixed function oxidase system. The Journal of biological chemistry. 1975 Academic Article GET IT
Times cited: 27
Drug metabolism in normal children, lead-poisoned children, and normal adults. Clinical pharmacology and therapeutics. 1975 Academic Article GET IT
Times cited: 67
Induction of aryl hydrocarbon hydroxylase by polychlorinated biphenyls in the foeto-placental unit and neonatal livers during lactation. FEBS letters. 1975 Academic Article GET IT
Times cited: 26
Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P-450 is not essential for this enzyme activity. Proceedings of the National Academy of Sciences of the United States of America. 1974 Academic Article GET IT
Times cited: 217
Inhibition of delta-aminolevulinate synthetase induction by alpha-amanitin in avian liver cell cultures. Biochimica et biophysica acta. 1974 Academic Article GET IT
Times cited: 5
Enhancement of RNA synthesis in avian liver cell cultures by a 5beta-steroid metabolite during induction of delta-aminolevulinate synthase. Proceedings of the National Academy of Sciences of the United States of America. 1974 Academic Article GET IT
Times cited: 13
Inhibited induction of hepatic delta-aminolevulinate synthetase in pregnancy. FEBS letters. 1974 Academic Article GET IT
Times cited: 1
Studies on the effects of methylmercury on ethylmorphine N-demethylase and aniline hydroxylase activities and on the conversion of cytochrome P-450 to cytochrome P-420. Drug metabolism and disposition: the biological fate of chemicals. 1974 Academic Article GET IT
Times cited: 12
Biosynthesis of delta-aminolevulinic acid and porphobilinogen in the domestic fowl (Gallus domesticus). Comparative biochemistry and physiology. B, Comparative biochemistry. 1974 Academic Article GET IT
Times cited: 15
Stimulators and inhibitors of hepatic porphyrin formation in human sera. The Journal of clinical investigation. 1974 Academic Article GET IT
A microassay for uroporphyrinogen I synthase, one of three abnormal enzyme activities in acute intermittent porphyria, and its application to the study of the genetics of this disease. Proceedings of the National Academy of Sciences of the United States of America. 1974 Academic Article GET IT
Times cited: 74
Induction of drug-metabolizing enzymes and aryl hydrocarbon hydroxylase by microscope immersion oil. Life sciences. 1974 Academic Article GET IT
Times cited: 8
Differences in inducibility of cutaneous and hepatic drug metabolizing enzymes and cytochrome P-450 by polychlorinated biphenyls and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT). The Journal of pharmacology and experimental therapeutics. 1974 Academic Article GET IT
Times cited: 62
The effect of progesterone on activities of delta-aminolevulinic acid synthetase and delta-aminolevulinic acid dehydratase in estrogen-primed avian oviduct. General and comparative endocrinology. 1974 Academic Article GET IT
Times cited: 17
Endocrine-gene interaction in the pathogenesis of acute intermittent porphyria. Research publications - Association for Research in Nervous and Mental Disease. 1974 Information Resource GET IT
Times cited: 5
Studies in porphyria. II. Evidence for a deficiency of steroid delta-4-5-alpha-reductase activity in acute intermittent porphyria. The Journal of experimental medicine. 1973 Academic Article GET IT
Times cited: 25
Studies in lead poisoning. I. Microanalysis of erythrocyte protoporphyrin levels by spectrophotometry in the detection of chronic lead intoxication in the subclinical range. Biochemical medicine. 1973 Academic Article GET IT
Times cited: 108
Studies in lead poisoning. II. Correlation between the ratio of activated to inactivated delta-aminolevulinic acid dehydratase of whole blood and the blood lead level. Biochemical medicine. 1973 Academic Article GET IT
Times cited: 144
Drug stimulation of -aminolevulinic acid synthetase and cytochrome P-450 in vivo in chick embryo liver. The Journal of pharmacology and experimental therapeutics. 1973 Academic Article GET IT
Times cited: 40
Polychlorinated biphenyls: a new type of inducer of cytochrome P-448 in the liver. Proceedings of the National Academy of Sciences of the United States of America. 1973 Academic Article GET IT
Times cited: 295
Chlorcyclizine N-demethylase activity in chick embryo hepatic cell culture. Biochemical pharmacology. 1973 Academic Article GET IT
Times cited: 3
Drug-induced alterations of steroid hormone metabolism in man. Annals of the New York Academy of Sciences. 1973 Academic Article GET IT
Times cited: 13
Inducibility of benzo( )pyrene hydroxylase in human skin by polycylic hydrocarbons. Clinical pharmacology and therapeutics. 1973 Academic Article GET IT
Times cited: 54
Induction of aryl hydrocarbon hydroxylase in human skin. Drug metabolism and disposition: the biological fate of chemicals. 1973 Academic Article GET IT
Times cited: 16
Studies on the inheritance of human erythrocyte delta-aminolevulinate dehydratase and uroporphyrinogen synthetase. Enzyme. 1973 Academic Article GET IT
The induction of a carcinogen-metabolizing enzyme in human skin. Transactions of the American Clinical and Climatological Association. 1973 Academic Article GET IT
Times cited: 1
Coproporphyrin I and 3 excretion in bile and urine. The Journal of clinical investigation. 1972 Academic Article GET IT
Times cited: 54
Studies in porphyria. I. A defect in the reductive transformation of natural steroid hormones in the hereditary liver disease, acute intermittent porphyria. The Journal of experimental medicine. 1972 Academic Article GET IT
Times cited: 31
Assays for porphyrins, delta-aminolevulinic-acid dehydratase, and porphyrinogen synthetase in microliter samples of whole blood: applications to metabolic defects involving the heme pathway. Proceedings of the National Academy of Sciences of the United States of America. 1972 Academic Article GET IT
Times cited: 143
A defect of steroid hormone metabolism in acute intermittent porphyria. Federation proceedings. 1972 Academic Article GET IT
Times cited: 10
Lead and methyl mercury: effects of acute exposure on cytochrome P-450 and the mixed function oxidase system in the liver. The Journal of experimental medicine. 1972 Academic Article GET IT
Times cited: 91
The inhibitory effect of coproporphyrins on amino acid uptake into proteins by porphyric liver cells. FEBS letters. 1972 Academic Article GET IT
Times cited: 3
Polychlorinated biphenyls: comparative effects of high and low chlorine containing Aroclors on hepatic mixed function oxidase. Research communications in chemical pathology and pharmacology. 1972 Academic Article GET IT
Times cited: 72
Induction of benzo( )pyrene hydroxylase in human skin. Science (New York, N.Y.). 1972 Academic Article GET IT
Times cited: 79
Influence of phenobarbital on the metabolism and analgesic effect of methadone in rats. The Journal of laboratory and clinical medicine. 1972 Academic Article GET IT
Times cited: 26
Interaction of cytochrome P-450 with antibodies raised against a solubilized P-450 preparation from hepatic microsomes. Molecular pharmacology. 1971 Academic Article GET IT
Times cited: 3
The influence of postnatal development on drug-induced hepatic porphyria and the synthesis of cytochrome P-450. A biochemical and morphological study. The Journal of experimental medicine. 1971 Academic Article GET IT
Times cited: 22
The metabolism of aminopyrine in chick embryo hepatic cell culture: effects of competitive substrates and carbon monoxide. Molecular pharmacology. 1971 Academic Article GET IT
Times cited: 15
Isolation and biochemical characterization of nuclei from chick embryo liver. The Journal of cell biology. 1971 Academic Article GET IT
Times cited: 8
Abnormal steroid hormone metabolism in the genetic liver disease acute intermittent porphyria. Annals of the New York Academy of Sciences. 1971 Academic Article GET IT
Times cited: 13
Inhibitory effect of a-amanitin on the induction of delta-aminolevulinate synthetase in chick embryo liver. FEBS letters. 1971 Academic Article GET IT
Preparation and properties of a solubilized form of cytochrome P-450 from chick embryo liver microsomes. Molecular pharmacology. 1971 Academic Article GET IT
Times cited: 18
The occurrence of substances in human serum which can regulate porphyrin synthesis in liver cells. Transactions of the American Clinical and Climatological Association. 1971 Information Resource GET IT
Times cited: 1
The influence of pregnancy and oral contraceptive steroids on the concentration of plasma proteins. Studies with a quantitative immunodiffusion method. American journal of obstetrics and gynecology. 1970 Academic Article GET IT
Times cited: 99
Stimulation of mammalian erythropoiesis by 5beta-H steroid metabolites. Proceedings of the National Academy of Sciences of the United States of America. 1970 Academic Article GET IT
Times cited: 72
Induction of hepatic delta-amino-levulinic acid synthetase by oral contraceptive steroids. The Journal of clinical endocrinology and metabolism. 1970 Academic Article GET IT
Times cited: 22
Hyperbeta-lipoproteinemia in acute intermittent porphyria; preliminary report. The New England journal of medicine. 1970 Academic Article GET IT
Times cited: 20
Stimulation of mammalian erythropoiesis by metabolites of steroid hormones. Transactions of the Association of American Physicians. 1970 Academic Article GET IT
Times cited: 3
The influence of hormones on hepatic function. Progress in liver diseases. 1970 Information Resource GET IT
Times cited: 5
5'-nucleotidase of plasma membranes of the rat liver: studies on subcellular distribution. Annals of the New York Academy of Sciences. 1969 Academic Article GET IT
Times cited: 24
The occurrence of substances in human plasma capable of inducing the enzyme delta-aminolevulinate synthetase in liver cells. Proceedings of the National Academy of Sciences of the United States of America. 1969 Academic Article GET IT
Times cited: 14
Plasma membranes of the rat liver. Isolation and enzymatic characterization of a fraction rich in bile canaliculi. The Journal of cell biology. 1969 Academic Article GET IT
Times cited: 152
Stimulation of hepatic porphyrin synthesis in tissue culture by sera of patients with acute porphyria. Transactions of the Association of American Physicians. 1969 Academic Article GET IT
Enzyme induction in the liver. Gastroenterology. 1968 Academic Article GET IT
Times cited: 4
THE INDUCTION OF delta-AMINOLEVULINIC ACID SYNTHETASE in vivo IN CHICK EMBRYO LIVER BY NATURAL STEROIDS. Proceedings of the National Academy of Sciences of the United States of America. 1968 Academic Article GET IT
The regulation of porphyrin and heme synthesis. Seminars in hematology. 1968 Academic Article GET IT
Times cited: 28
Experimental hepatic porphyria: studies with steroids of physiological origin in man. Annals of the New York Academy of Sciences. 1968 Academic Article GET IT
Times cited: 13
Steroid induction of porphyrin synthesis in liver cell culture. II. The effects of heme, uridine diphosphate glucuronic acid, and inhibitors of nucleic acid and protein synthesis on the induction process. The Journal of biological chemistry. 1968 Academic Article GET IT
Times cited: 67
Influence of estradiol and estriol on urinary excretion of hydroxyproline in man. The Journal of laboratory and clinical medicine. 1968 Academic Article GET IT
Times cited: 23
The effects of estradiol and estriol on plasma levels of cortisol and thyroid hormone-binding globulins and on aldosterone and cortisol secretion rates in man. The Journal of clinical investigation. 1967 Academic Article GET IT
Times cited: 44
Steroid induction of porphyrin synthesis in liver cell culture. I. Structural basis and possible physiological role in the control of heme formation. The Journal of biological chemistry. 1967 Academic Article GET IT
Times cited: 98
Stimulation of hemoglobin synthesis in chick blastoderms by certain 5beta androstane and 5beta pregnane steroids. Proceedings of the National Academy of Sciences of the United States of America. 1967 Academic Article GET IT
Times cited: 86
Steroid control of porphyrin and heme biosynthesis: a new biological function of steroid hormone metabolites. Proceedings of the National Academy of Sciences of the United States of America. 1967 Academic Article GET IT
Times cited: 51
Steroid induction of porphyrin synthesis in liver cell culture. Transactions of the Association of American Physicians. 1967 Academic Article GET IT
Times cited: 3
The effects of penicillamine therapy on uric acid metabolism in Wilson's disease. Transactions of the Association of American Physicians. 1966 Academic Article GET IT
Times cited: 2
Studies on the mechanism and structural specificity of the estrogen effect on BSP metabolism. Transactions of the Association of American Physicians. 1965 Academic Article GET IT
Times cited: 3
EFFECT OF OESTRADIOL ON BONE MARROW TRANSPLANTATION IN LETHALLY IRRADIATED MICE. Nature. 1964 Academic Article GET IT
Times cited: 2
STEROID FEVER AND INFLAMMATION. STUDIES WITH 11-KETOPREGNANOLONE IN MAN. Archives of internal medicine. 1964 Academic Article GET IT
Times cited: 5
Fever-producing steroids of endogenous origin in man. Archives of internal medicine. 1960 Academic Article GET IT
Times cited: 11
Influence of invasiveness, hormones, and amphenone on steroids in adrenal carcinoma. Science (New York, N.Y.). 1956 Academic Article GET IT
Times cited: 4

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Background

education and training

M.D., University of Chicago Pritzker School of Medicine 1950
A.B., Columbia University 1947

Contact

full name

Attallah Kappas

VIVO Weill Cornell Medical College

Attallah Kappas Professor Emeritus of Medicine

Publications

selected publications

Background

education and training

Contact

full name

Phone

Publications

selected publications

Background

education and training

Contact

full name