CAR-A astrocytes for Alzheimer's: Promise and challenge. Academic Article uri icon

Overview

abstract

  • In a recent study in Science, Chen et al. engineer astrocytes with anti-amyloid chimeric antigen receptors (CARs) to enable sustained, antigen-directed clearance of amyloid-β (Aβ) in vivo, revealing how CAR design can shape both pathology and glial responses.

publication date

  • May 7, 2026

Research

keywords

  • Alzheimer Disease
  • Astrocytes
  • Receptors, Chimeric Antigen

Identity

Digital Object Identifier (DOI)

  • 10.1016/j.stem.2026.04.008

PubMed ID

  • 42102723

Additional Document Info

volume

  • 33

issue

  • 5