selected publications
- Type I interferon exacerbates Mycobacterium tuberculosis induced human macrophage death. EMBO reports. 2024 Academic Article GET IT
- Interferon-γ and infectious diseases: Lessons and prospects. Science (New York, N.Y.). 2024 Review GET IT
- Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase. Science advances. 2024 Academic Article GET IT
- Neutrophil-plasmacytoid dendritic cell interaction leads to production of type I IFN in response to Mycobacterium tuberculosis. European journal of immunology. 2023 Academic Article GET IT
- Mycobacterium tuberculosis as teacher. Nature microbiology. 2023 Academic Article GET IT
-
Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.
ACS medicinal chemistry letters.
2023
Academic Article
GET IT
Times cited: 4 - Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance. Cell chemical biology. 2023 Academic Article GET IT
- Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II. Journal of medicinal chemistry. 2023 Academic Article GET IT
- Transcriptional Biomarkers of Differentially Detectable Mycobacterium tuberculosis in Patient Sputum. mBio. 2022 Academic Article GET IT
- Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors. Journal of medicinal chemistry. 2022 Academic Article GET IT
- Nonresolving inflammation redux. Immunity. 2022 Review GET IT
- Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions. ACS infectious diseases. 2022 Academic Article GET IT
-
In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
Journal of medicinal chemistry.
2022
Academic Article
GET IT
Times cited: 13 -
Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected.
Science translational medicine.
2021
Academic Article
GET IT
Times cited: 13 -
Characterization of Phosphopantetheinyl Hydrolase from Mycobacterium tuberculosis.
Microbiology spectrum.
2021
Academic Article
GET IT
Times cited: 1 -
Multiform antimicrobial resistance from a metabolic mutation.
Science advances.
2021
Academic Article
GET IT
Times cited: 25 - Surmounting structural barriers to tackle endemic infectious diseases. The Journal of experimental medicine. 2021 Academic Article GET IT
- Characterization of Differentially Detectable Mycobacterium tuberculosis in the Sputum of Subjects with Drug-Sensitive or Drug-Resistant Tuberculosis before and after Two Months of Therapy. Antimicrobial agents and chemotherapy. 2021 Academic Article GET IT
-
Rethinking immunology.
Science (New York, N.Y.).
2021
Comment
GET IT
Times cited: 10 -
Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.
Journal of medicinal chemistry.
2021
Academic Article
GET IT
Times cited: 11 -
Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice.
Angewandte Chemie (International ed. in English).
2021
Academic Article
GET IT
Times cited: 22 - Noncytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells In Vitro and Suppresses Cutaneous Inflammation in the Mouse. Journal of immunology (Baltimore, Md. : 1950). 2021 Academic Article GET IT
-
Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis.
Nature communications.
2021
Academic Article
GET IT
Times cited: 27 - Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions. ACS infectious diseases. 2021 Academic Article GET IT
- Type I interferon signaling mediates Mycobacterium tuberculosis-induced macrophage death. The Journal of experimental medicine. 2021 Academic Article GET IT
- A Multistress Model for High Throughput Screening Against Nonreplicating Mycobacterium tuberculosis. Methods in molecular biology (Clifton, N.J.). 2021 Article GET IT
-
Nonredundant functions of Mycobacterium tuberculosis chaperones promote survival under stress.
Molecular microbiology.
2020
Academic Article
GET IT
Times cited: 4 -
Structure-Activity Relationships of Noncovalent Immunoproteasome β5i-Selective Dipeptides.
Journal of medicinal chemistry.
2020
Academic Article
GET IT
Times cited: 10 -
Neutrophils and COVID-19: Nots, NETs, and knots.
The Journal of experimental medicine.
2020
Comment
GET IT
Times cited: 29 -
Biology of antimicrobial resistance and approaches to combat it.
Science translational medicine.
2020
Information Resource
GET IT
Times cited: 109 -
Activity-Based Protein Profiling Reveals That Cephalosporins Selectively Active on Non-replicating Mycobacterium tuberculosis Bind Multiple Protein Families and Spare Peptidoglycan Transpeptidases.
Frontiers in microbiology.
2020
Academic Article
GET IT
Times cited: 11 -
Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB.
PLoS pathogens.
2020
Academic Article
GET IT
Times cited: 9 -
Early Bactericidal Activity Trial of Nitazoxanide for Pulmonary Tuberculosis.
Antimicrobial agents and chemotherapy.
2020
Academic Article
GET IT
Times cited: 22 - JEM goes viral. The Journal of experimental medicine. 2020 Editorial Article GET IT
- Structural insights into phosphopantetheinyl hydrolase PptH from Mycobacterium tuberculosis. Protein science : a publication of the Protein Society. 2020 Academic Article GET IT
-
Selective Phenylimidazole-Based Inhibitors of the Mycobacterium tuberculosis Proteasome.
Journal of medicinal chemistry.
2019
Academic Article
GET IT
Times cited: 15 -
Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA.
mBio.
2019
Academic Article
GET IT
Times cited: 7 -
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis.
ACS infectious diseases.
2019
Academic Article
GET IT
Times cited: 10 -
Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in Mycobacterium tuberculosis.
ACS infectious diseases.
2019
Academic Article
GET IT
Times cited: 6 - Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma. The Journal of antibiotics. 2019 Academic Article GET IT
-
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.
Science (New York, N.Y.).
2019
Academic Article
GET IT
Times cited: 53 -
Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis.
ACS infectious diseases.
2018
Academic Article
GET IT
Times cited: 24 -
Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment.
mBio.
2018
Academic Article
GET IT
Times cited: 28 -
Correction: Improved Control of Tuberculosis and Activation of Macrophages in Mice Lacking Protein Kinase R.
2018
GET IT
Times cited: 2 -
ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB.
Proceedings of the National Academy of Sciences of the United States of America.
2018
Academic Article
GET IT
Times cited: 58 -
Evidence for dispensability of protein kinase R in host control of tuberculosis.
European journal of immunology.
2018
Academic Article
GET IT
Times cited: 8 -
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.
ACS infectious diseases.
2018
Academic Article
GET IT
Times cited: 17 -
Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes.
Nature communications.
2017
Academic Article
GET IT
Times cited: 44 - Introduction of Laurie H. Glimcher, MD. The Journal of clinical investigation. 2017 Academic Article GET IT
-
Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis.
mBio.
2017
Academic Article
GET IT
Times cited: 42 -
Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
Proceedings of the National Academy of Sciences of the United States of America.
2017
Academic Article
GET IT
Times cited: 59 - A time of change. The Journal of experimental medicine. 2017 Editorial Article GET IT
-
Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome.
Biochemistry.
2016
Academic Article
GET IT
Times cited: 14 -
Visualization of the Charcoal Agar Resazurin Assay for Semi-quantitative, Medium-throughput Enumeration of Mycobacteria.
Journal of visualized experiments : JoVE.
2016
Academic Article
GET IT
Times cited: 8 -
Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice.
Proceedings of the National Academy of Sciences of the United States of America.
2016
Academic Article
GET IT
Times cited: 57 -
Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome.
ACS infectious diseases.
2016
Academic Article
GET IT
Times cited: 21 -
Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK.
Proceedings of the National Academy of Sciences of the United States of America.
2016
Academic Article
GET IT
Times cited: 39 -
Immunoproteasome β5i-Selective Dipeptidomimetic Inhibitors.
ChemMedChem.
2016
Academic Article
GET IT
Times cited: 27 -
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
PLoS pathogens.
2016
Academic Article
GET IT
Times cited: 222 -
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America.
2016
Academic Article
GET IT
Times cited: 72 -
Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.
Journal of medicinal chemistry.
2016
Academic Article
GET IT
Times cited: 39 -
Human studies at JEM: Immunology and beyond.
The Journal of experimental medicine.
2016
Editorial Article
GET IT
Times cited: 2 -
Comparison of transposon and deletion mutants in Mycobacterium tuberculosis: The case of rv1248c, encoding 2-hydroxy-3-oxoadipate synthase.
Tuberculosis (Edinburgh, Scotland).
2015
Academic Article
GET IT
Times cited: 6 -
IMMUNOLOGY. From transient infection to chronic disease.
Science (New York, N.Y.).
2015
Comment
GET IT
Times cited: 4 -
Cooperative development of antimicrobials: looking back to look ahead.
Nature reviews. Microbiology.
2015
Review
GET IT
Times cited: 25 -
E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress.
Proceedings of the National Academy of Sciences of the United States of America.
2015
Academic Article
GET IT
Times cited: 46 -
Rapid, Semiquantitative Assay To Discriminate among Compounds with Activity against Replicating or Nonreplicating Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy.
2015
Academic Article
GET IT
Times cited: 35 -
Identification of Novel Anti-mycobacterial Compounds by Screening a Pharmaceutical Small-Molecule Library against Nonreplicating Mycobacterium tuberculosis.
ACS infectious diseases.
2015
Academic Article
GET IT
Times cited: 27 -
Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis.
PloS one.
2015
Academic Article
GET IT
Times cited: 18 -
TB drug development: immunology at the table.
Immunological reviews.
2015
Review
GET IT
Times cited: 36 - Video podcast: Tuberculosis. Immunological reviews. 2015 Editorial Article GET IT
-
What can immunology contribute to the control of the world's leading cause of death from bacterial infection?.
Immunological reviews.
2015
Editorial Article
GET IT
Times cited: 4 -
Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.
Cell host & microbe.
2015
Academic Article
GET IT
Times cited: 80 -
A multi-stress model for high throughput screening against non-replicating Mycobacterium tuberculosis.
Methods in molecular biology (Clifton, N.J.).
2015
Academic Article
GET IT
Times cited: 35 -
Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.
ACS chemical biology.
2014
Academic Article
GET IT
Times cited: 28 -
Antibiotic resistance--problems, progress, and prospects.
The New England journal of medicine.
2014
Academic Article
GET IT
Times cited: 250 -
Isocitrate lyase mediates broad antibiotic tolerance in Mycobacterium tuberculosis.
Nature communications.
2014
Academic Article
GET IT
Times cited: 152 -
Synthetic calanolides with bactericidal activity against replicating and nonreplicating Mycobacterium tuberculosis.
Journal of medicinal chemistry.
2014
Academic Article
GET IT
Times cited: 58 -
Oxathiazolones Selectively Inhibit the Human Immunoproteasome over the Constitutive Proteasome.
ACS medicinal chemistry letters.
2014
Academic Article
GET IT
Times cited: 43 -
Drug-resistant tuberculosis: a new shot on goal.
Nature medicine.
2014
Comment
GET IT
Times cited: 6 -
Benzimidazole-based compounds kill Mycobacterium tuberculosis.
European journal of medicinal chemistry.
2014
Academic Article
GET IT
Times cited: 33 -
Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase.
Biochemistry.
2013
Academic Article
GET IT
Times cited: 16 -
Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America.
2013
Academic Article
GET IT
Times cited: 81 -
Nitrite produced by Mycobacterium tuberculosis in human macrophages in physiologic oxygen impacts bacterial ATP consumption and gene expression.
Proceedings of the National Academy of Sciences of the United States of America.
2013
Academic Article
GET IT
Times cited: 76 -
A journey in science: promise, purpose, privilege.
Molecular medicine (Cambridge, Mass.).
2013
Academic Article
GET IT
Times cited: 1 -
Nitrite impacts the survival of Mycobacterium tuberculosis in response to isoniazid and hydrogen peroxide.
MicrobiologyOpen.
2013
Academic Article
GET IT
Times cited: 22 -
Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis.
PloS one.
2013
Academic Article
GET IT
Times cited: 61 -
N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.
Journal of the American Chemical Society.
2013
Academic Article
GET IT
Times cited: 48 -
Influence of allosteric regulators on individual steps in the reaction catalyzed by Mycobacterium tuberculosis 2-hydroxy-3-oxoadipate synthase.
The Journal of biological chemistry.
2013
Academic Article
GET IT
Times cited: 20 -
SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection.
Journal of immunology (Baltimore, Md. : 1950).
2013
Academic Article
GET IT
Times cited: 44 -
Beyond oxidative stress: an immunologist's guide to reactive oxygen species.
Nature reviews. Immunology.
2013
Information Resource
GET IT
Times cited: 1180 -
Efficacy of nitazoxanide against clinical isolates of Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy.
2013
Academic Article
GET IT
Times cited: 33 -
Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
GET IT
Times cited: 94 -
Fresh approaches to anti-infective therapies.
Science translational medicine.
2012
Information Resource
GET IT
Times cited: 133 -
dSarm/Sarm1 is required for activation of an injury-induced axon death pathway.
Science (New York, N.Y.).
2012
Academic Article
GET IT
Times cited: 497 -
Secretory products of macrophages: twenty-five years on.
The Journal of clinical investigation.
2012
Article
GET IT
Times cited: 20 -
Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase R.
PloS one.
2012
Academic Article
GET IT
Times cited: 36 -
Remembering Ralph Steinman.
The Journal of experimental medicine.
2011
Academic Article
GET IT
Times cited: 6 -
Is iNOS beginning to smoke?.
Cell.
2011
Comment
GET IT
Times cited: 12 -
In vitro differentiation of human macrophages with enhanced antimycobacterial activity.
The Journal of clinical investigation.
2011
Academic Article
GET IT
Times cited: 82 -
Mycobacterium tuberculosis gene Rv2136c is dispensable for acid resistance and virulence in mice.
Tuberculosis (Edinburgh, Scotland).
2011
Academic Article
GET IT
Times cited: 6 -
Identification of new inhibitors of protein kinase R guided by statistical modeling.
Bioorganic & medicinal chemistry letters.
2011
Academic Article
GET IT
Times cited: 18 -
Identification of a chemical that inhibits the mycobacterial UvrABC complex in nucleotide excision repair.
Biochemistry.
2011
Academic Article
GET IT
Times cited: 31 -
Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes.
Cell host & microbe.
2011
Academic Article
GET IT
Times cited: 100 - Nitazoxanide Disrupts Membrane Potential and Intrabacterial pH Homeostasis of Mycobacterium tuberculosis. ACS medicinal chemistry letters. 2011 Academic Article GET IT
-
Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity.
PloS one.
2010
Academic Article
GET IT
Times cited: 118 -
Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates.
Chemistry & biology.
2010
Academic Article
GET IT
Times cited: 243 -
A protecting group-free synthesis of deazathiamine: a step toward inhibitor design.
Bioorganic & medicinal chemistry letters.
2010
Academic Article
GET IT
Times cited: 11 -
Induction of ER stress in macrophages of tuberculosis granulomas.
PloS one.
2010
Academic Article
GET IT
Times cited: 114 -
Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2010
Academic Article
GET IT
Times cited: 145 -
Fellutamide B is a potent inhibitor of the Mycobacterium tuberculosis proteasome.
Archives of biochemistry and biophysics.
2010
Academic Article
GET IT
Times cited: 54 -
Killing of non-replicating Mycobacterium tuberculosis by 8-hydroxyquinoline.
The Journal of antimicrobial chemotherapy.
2010
Academic Article
GET IT
Times cited: 59 -
Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase.
Chemistry & biology.
2010
Academic Article
GET IT
Times cited: 98 -
Nonresolving inflammation.
Cell.
2010
Information Resource
GET IT
Times cited: 1194 -
SnapShot: Reactive Oxygen Intermediates (ROI).
Cell.
2010
Article
GET IT
Times cited: 137 -
Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase .
Biochemistry.
2010
Academic Article
GET IT
Times cited: 23 -
Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice.
The Journal of experimental medicine.
2009
Academic Article
GET IT
Times cited: 395 -
N-iminoethyl-L-lysine improves memory and reduces amyloid pathology in a transgenic mouse model of amyloid deposition.
Neurochemistry international.
2009
Academic Article
GET IT
Times cited: 12 -
Structural insights on the Mycobacterium tuberculosis proteasomal ATPase Mpa.
Structure (London, England : 1993).
2009
Academic Article
GET IT
Times cited: 67 -
Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance.
Journal of medicinal chemistry.
2009
Academic Article
GET IT
Times cited: 107 -
Inhibitors selective for mycobacterial versus human proteasomes.
Nature.
2009
Academic Article
GET IT
Times cited: 191 -
Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease.
Journal of neurochemistry.
2009
Academic Article
GET IT
Times cited: 96 -
Mycobacterium tuberculosis expresses methionine sulphoxide reductases A and B that protect from killing by nitrite and hypochlorite.
Molecular microbiology.
2009
Academic Article
GET IT
Times cited: 67 -
Microbiology. An antibiotic mimics immunity.
Science (New York, N.Y.).
2008
Comment
GET IT
Times cited: 14 -
Acid-susceptible mutants of Mycobacterium tuberculosis share hypersusceptibility to cell wall and oxidative stress and to the host environment.
Journal of bacteriology.
2008
Academic Article
GET IT
Times cited: 126 -
Distinct specificities of Mycobacterium tuberculosis and mammalian proteasomes for N-acetyl tripeptide substrates.
The Journal of biological chemistry.
2008
Academic Article
GET IT
Times cited: 48 -
Identification of a copper-binding metallothionein in pathogenic mycobacteria.
Nature chemical biology.
2008
Academic Article
GET IT
Times cited: 174 -
A philosophy of anti-infectives as a guide in the search for new drugs for tuberculosis.
Tuberculosis (Edinburgh, Scotland).
2008
Review
GET IT
Times cited: 51 -
A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis.
Nature medicine.
2008
Academic Article
GET IT
Times cited: 271 -
Epidemic inflammation: pondering obesity.
Molecular medicine (Cambridge, Mass.).
2008
Information Resource
GET IT
Times cited: 112 -
Metchnikoff's Legacy in 2008.
Nature immunology.
2008
Conference Paper
GET IT
Times cited: 29 -
Selective killing of nonreplicating mycobacteria.
Cell host & microbe.
2008
Academic Article
GET IT
Times cited: 159 -
MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival.
The Journal of experimental medicine.
2007
Academic Article
GET IT
Times cited: 176 -
Man is not a mouse: reply.
Journal of leukocyte biology.
2007
Letter
GET IT
Times cited: 24 -
Role of iNOS in human host defense.
Science (New York, N.Y.).
2006
Article
GET IT
Times cited: 55 -
Cytosolic phospholipase A2 enzymes are not required by mouse bone marrow-derived macrophages for the control of Mycobacterium tuberculosis in vitro.
Infection and immunity.
2006
Academic Article
GET IT
Times cited: 14 -
Mycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificity.
Molecular microbiology.
2006
Academic Article
GET IT
Times cited: 90 -
Neutrophils and immunity: challenges and opportunities.
Nature reviews. Immunology.
2006
Information Resource
GET IT
Times cited: 1899 -
Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate.
Molecular microbiology.
2006
Academic Article
GET IT
Times cited: 108 -
Abrupt expression of TLR4 in TLR4-deficient macrophages imposes a selective disadvantage: genetic evidence for TLR4-dependent responses to endogenous, nonmicrobial stimuli.
Journal of immunology (Baltimore, Md. : 1950).
2006
Academic Article
GET IT
Times cited: 3 -
Chemical inhibitors of TNF signal transduction in human neutrophils point to distinct steps in cell activation.
Journal of leukocyte biology.
2005
Academic Article
GET IT
Times cited: 8 -
Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase.
The Journal of experimental medicine.
2005
Academic Article
GET IT
Times cited: 183 -
Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis.
The Journal of biological chemistry.
2005
Academic Article
GET IT
Times cited: 27 -
Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes.
Molecular microbiology.
2005
Academic Article
GET IT
Times cited: 70 -
Role for nucleotide excision repair in virulence of Mycobacterium tuberculosis.
Infection and immunity.
2005
Academic Article
GET IT
Times cited: 101 -
Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils.
The Journal of experimental medicine.
2005
Academic Article
GET IT
Times cited: 59 -
Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase.
Proceedings of the National Academy of Sciences of the United States of America.
2005
Academic Article
GET IT
Times cited: 167 -
Mycobacterium tuberculosis and the host response.
The Journal of experimental medicine.
2005
Review
GET IT
Times cited: 114 -
A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP.
Molecular microbiology.
2005
Academic Article
GET IT
Times cited: 112 -
Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue.
Molecular microbiology.
2005
Academic Article
GET IT
Times cited: 104 -
S-nitroso proteome of Mycobacterium tuberculosis: Enzymes of intermediary metabolism and antioxidant defense.
Proceedings of the National Academy of Sciences of the United States of America.
2004
Academic Article
GET IT
Times cited: 146 -
The moving frontier in nitric oxide-dependent signaling.
Science's STKE : signal transduction knowledge environment.
2004
Review
GET IT
Times cited: 28 -
Identification of Mycobacterium tuberculosis counterimmune (cim) mutants in immunodeficient mice by differential screening.
Infection and immunity.
2004
Academic Article
GET IT
Times cited: 46 -
The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide.
Science (New York, N.Y.).
2003
Academic Article
GET IT
Times cited: 395 -
MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis.
The Journal of experimental medicine.
2003
Academic Article
GET IT
Times cited: 127 -
Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment.
The Journal of experimental medicine.
2003
Academic Article
GET IT
Times cited: 1202 -
Immunology: Oxygen and the inflammatory cell.
Nature.
2003
Article
GET IT
Times cited: 68 -
Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling.
The Journal of clinical investigation.
2003
Information Resource
GET IT
Times cited: 408 -
Critical role of the carboxyl terminus of proline-rich tyrosine kinase (Pyk2) in the activation of human neutrophils by tumor necrosis factor: separation of signals for the respiratory burst and degranulation.
The Journal of experimental medicine.
2003
Academic Article
GET IT
Times cited: 48 -
Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair.
Cell.
2002
Academic Article
GET IT
Times cited: 488 -
Points of control in inflammation.
Nature.
2002
Review
GET IT
Times cited: 1809 -
Inducible nitric oxide synthase in the tuberculous human lung.
American journal of respiratory and critical care medicine.
2002
Editorial Article
GET IT
Times cited: 43 -
Nonredundant antioxidant defense by multiple two-cysteine peroxiredoxins in human prostate cancer cells.
Molecular medicine (Cambridge, Mass.).
2002
Academic Article
GET IT
Times cited: 42 -
Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein.
Science (New York, N.Y.).
2002
Academic Article
GET IT
Times cited: 297 - Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function. Archives of biochemistry and biophysics. 2002 Information Resource GET IT
-
Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase.
The Journal of experimental medicine.
2001
Academic Article
GET IT
Times cited: 405 -
Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates.
Proceedings of the National Academy of Sciences of the United States of America.
2001
Academic Article
GET IT
Times cited: 183 -
TREM-1: a new regulator of innate immunity in sepsis syndrome.
Nature medicine.
2001
Article
GET IT
Times cited: 86 -
Putting the brakes on innate immunity: a regulatory role for CD200?.
Nature immunology.
2001
Article
GET IT
Times cited: 64 -
Peroxynitrite reductase activity of bacterial peroxiredoxins.
Nature.
2000
Academic Article
GET IT
Times cited: 546 -
Antisense RNA to eIF4E suppresses oncogenic properties of a head and neck squamous cell carcinoma cell line.
The Laryngoscope.
2000
Academic Article
GET IT
Times cited: 83 -
Elevation of IL-18 in human sepsis.
Journal of clinical immunology.
2000
Academic Article
GET IT
Times cited: 73 -
Reactive nitrogen intermediates and the pathogenesis of Salmonella and mycobacteria.
Current opinion in microbiology.
2000
Information Resource
GET IT
Times cited: 130 -
Echocardiographic and survival studies in mice undergoing endotoxic shock: effects of genetic ablation of inducible nitric oxide synthase and pharmacologic antagonism of platelet-activating factor.
The Journal of surgical research.
1999
Academic Article
GET IT
Times cited: 15 -
Suppression of macrophage responses to bacterial lipopolysaccharide by a non-secretory form of secretory leukocyte protease inhibitor.
Biochimica et biophysica acta.
1999
Academic Article
GET IT
Times cited: 32 -
Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock.
Molecular medicine (Cambridge, Mass.).
1999
Academic Article
GET IT
Times cited: 38 -
Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF.
The Journal of clinical investigation.
1999
Academic Article
GET IT
Times cited: 116 -
noxR3, a novel gene from Mycobacterium tuberculosis, protects Salmonella typhimurium from nitrosative and oxidative stress.
Infection and immunity.
1999
Academic Article
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Times cited: 53 -
Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide.
Proceedings of the National Academy of Sciences of the United States of America.
1999
Academic Article
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Times cited: 178 -
Lethality of endotoxin in mice genetically deficient in the respiratory burst oxidase, inducible nitric oxide synthase, or both.
Shock (Augusta, Ga.).
1999
Academic Article
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Times cited: 38 -
Paradoxical preservation of a lipopolysaccharide response in C3H/HeJ macrophages: induction of matrix metalloproteinase-9.
Journal of immunology (Baltimore, Md. : 1950).
1999
Academic Article
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Times cited: 20 - Progressive amplification and overexpression of the eukaryotic initiation factor 4E gene in different zones of head and neck cancers. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 1999 Academic Article GET IT
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Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani.
The Journal of experimental medicine.
1999
Academic Article
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Times cited: 368 -
A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity.
Cancer research.
1999
Academic Article
GET IT
Times cited: 272 -
Competitive PCR to detect eIF4E gene amplification in head and neck cancer.
Head & neck.
1999
Academic Article
GET IT
Times cited: 29 -
Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase.
Immunity.
1999
Academic Article
GET IT
Times cited: 409 -
Identification of genes involved in innate responsiveness to bacterial products by differential display.
Methods (San Diego, Calif.).
1998
Academic Article
GET IT
Times cited: 4 -
Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice.
The Journal of experimental medicine.
1998
Academic Article
GET IT
Times cited: 167 -
Utility of serial rectal swab cultures for detection of ceftazidime- and imipenem-resistant gram-negative bacilli from patients in the intensive care unit.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
1998
Academic Article
GET IT
Times cited: 7 -
Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection.
Journal of virology.
1998
Academic Article
GET IT
Times cited: 59 -
Effects of postoperative external beam irradiation after carotid artery stripping of nodal metastasis.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
1998
Academic Article
GET IT
Times cited: 2 -
Lipopolysaccharide-related stimuli induce expression of the secretory leukocyte protease inhibitor, a macrophage-derived lipopolysaccharide inhibitor.
Infection and immunity.
1998
Academic Article
GET IT
Times cited: 95 - [Non-obstructive azoospermia and ICSI]. Contraception, fertilite, sexualite (1992). 1998 Academic Article GET IT
-
Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates.
Molecular cell.
1998
Academic Article
GET IT
Times cited: 162 -
Immune response during HIV and tuberculosis co-infection.
Memorias do Instituto Oswaldo Cruz.
1998
Academic Article
GET IT
Times cited: 6 -
Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock.
The Journal of experimental medicine.
1998
Academic Article
GET IT
Times cited: 430 -
Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages.
Cancer research.
1998
Academic Article
GET IT
Times cited: 312 -
Periplasmic superoxide dismutase protects Salmonella from products of phagocyte NADPH-oxidase and nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America.
1997
Academic Article
GET IT
Times cited: 330 -
A novel antioxidant gene from Mycobacterium tuberculosis.
The Journal of experimental medicine.
1997
Academic Article
GET IT
Times cited: 91 -
Inducible nitric oxide synthase: what difference does it make?.
The Journal of clinical investigation.
1997
Information Resource
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Times cited: 859 -
Inducible nitric oxide synthase-deficient mice have enhanced leukocyte-endothelium interactions in endotoxemia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
1997
Academic Article
GET IT
Times cited: 243 -
Elevated expression of eIF4E and FGF-2 isoforms during vascularization of breast carcinomas.
Oncogene.
1997
Academic Article
GET IT
Times cited: 118 -
Evaluation of bacterial survival and phagocyte function with a fluorescence-based microplate assay.
Infection and immunity.
1997
Academic Article
GET IT
Times cited: 100 -
Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer.
Oncogene.
1997
Academic Article
GET IT
Times cited: 164 -
Identification of nitric oxide synthase as a protective locus against tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America.
1997
Academic Article
GET IT
Times cited: 940 -
Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide.
Cell.
1997
Academic Article
GET IT
Times cited: 313 -
Bacterial infection induces nitric oxide synthase in human neutrophils.
The Journal of clinical investigation.
1997
Academic Article
GET IT
Times cited: 255 -
Nitric oxide and macrophage function.
Annual review of immunology.
1997
Review
GET IT
Times cited: 3313 -
The Columbia-Cornell Alliance: a strategic response to a changing health care environment.
JAMA.
1996
Academic Article
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Times cited: 4 -
Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease.
The Journal of experimental medicine.
1996
Academic Article
GET IT
Times cited: 268 -
Inducible nitric oxide synthase requires both the canonical calmodulin-binding domain and additional sequences in order to bind calmodulin and produce nitric oxide in the absence of free Ca2+.
The Journal of biological chemistry.
1996
Academic Article
GET IT
Times cited: 87 -
Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes.
Proceedings of the National Academy of Sciences of the United States of America.
1996
Academic Article
GET IT
Times cited: 79 -
Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis.
The Journal of experimental medicine.
1996
Academic Article
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Times cited: 411 -
Ceramide selectively inhibits early events in the response of human neutrophils to tumor necrosis factor.
Journal of leukocyte biology.
1996
Academic Article
GET IT
Times cited: 18 -
Inducible nitric oxide synthase: identification of amino acid residues essential for dimerization and binding of tetrahydrobiopterin.
Proceedings of the National Academy of Sciences of the United States of America.
1995
Academic Article
GET IT
Times cited: 73 -
Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha.
The Journal of clinical investigation.
1995
Academic Article
GET IT
Times cited: 200 -
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase.
Cell.
1995
Academic Article
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Times cited: 1252 -
Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells.
The Journal of experimental medicine.
1995
Academic Article
GET IT
Times cited: 328 -
Vesicle membrane association of nitric oxide synthase in primary mouse macrophages.
Journal of immunology (Baltimore, Md. : 1950).
1995
Academic Article
GET IT
Times cited: 114 -
Beta 2 integrin-dependent tyrosine phosphorylation of paxillin in human neutrophils treated with tumor necrosis factor.
The Journal of cell biology.
1994
Academic Article
GET IT
Times cited: 107 -
Carboxyl terminus of inducible nitric oxide synthase. Contribution to NADPH binding and enzymatic activity.
The Journal of biological chemistry.
1994
Academic Article
GET IT
Times cited: 76 -
Nitric oxide synthases: roles, tolls, and controls.
Cell.
1994
Review
GET IT
Times cited: 2659 -
Role of interferon regulatory factor 1 in induction of nitric oxide synthase.
The Journal of experimental medicine.
1994
Academic Article
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Times cited: 461 - Cytokine regulation of nitric oxide synthase in mouse retinal pigment epithelial cells in culture. Experimental eye research. 1994 Academic Article GET IT
-
Nitric oxide and biopterin: a study in Chiaroscuro.
The Journal of clinical investigation.
1994
Editorial Article
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Times cited: 14 -
Inactivation of nitric oxide synthase after prolonged incubation of mouse macrophages with IFN-gamma and bacterial lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950).
1994
Academic Article
GET IT
Times cited: 123 -
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.
The Journal of biological chemistry.
1994
Academic Article
GET IT
Times cited: 2020 -
Mechanism of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages.
Journal of leukocyte biology.
1994
Academic Article
GET IT
Times cited: 208 -
Hemorrhagic tumor necrosis during a pilot trial of tumor necrosis factor-alpha and anti-GD3 ganglioside monoclonal antibody in patients with metastatic melanoma.
Blood.
1994
Academic Article
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Times cited: 47 - Nitrite production by stimulated human polymorphonuclear leukocytes supplemented with azide and catalase. Biochemical and biophysical research communications. 1993 Academic Article GET IT
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Taxol shares the ability of bacterial lipopolysaccharide to induce tyrosine phosphorylation of microtubule-associated protein kinase.
Journal of immunology (Baltimore, Md. : 1950).
1993
Academic Article
GET IT
Times cited: 111 -
Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase.
Science (New York, N.Y.).
1993
Academic Article
GET IT
Times cited: 731 -
Transcription and translation of inducible nitric oxide synthase in the pancreas of prediabetic BB rats.
FEBS letters.
1993
Academic Article
GET IT
Times cited: 130 -
Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta.
The Journal of experimental medicine.
1993
Academic Article
GET IT
Times cited: 632 -
Suppression of arthritis by an inhibitor of nitric oxide synthase.
The Journal of experimental medicine.
1993
Academic Article
GET IT
Times cited: 616 -
Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin).
The Journal of cell biology.
1993
Academic Article
GET IT
Times cited: 125 -
Traces of bacterial lipopolysaccharide suppress IFN-gamma-induced nitric oxide synthase gene expression in primary mouse macrophages.
Journal of immunology (Baltimore, Md. : 1950).
1993
Academic Article
GET IT
Times cited: 62 -
Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide.
The Journal of experimental medicine.
1993
Academic Article
GET IT
Times cited: 1052 -
Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor.
The Journal of cell biology.
1993
Academic Article
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Times cited: 150 -
Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon-gamma and bacterial lipopolysaccharide.
Transactions of the Association of American Physicians.
1993
Academic Article
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Times cited: 38 -
Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10.
The Journal of biological chemistry.
1992
Academic Article
GET IT
Times cited: 485 -
Role of nitric oxide in antagonistic effects of transforming growth factor-beta and interleukin-1 beta on the beating rate of cultured cardiac myocytes.
Molecular endocrinology (Baltimore, Md.).
1992
Academic Article
GET IT
Times cited: 153 -
Nitric oxide as a secretory product of mammalian cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
1992
Information Resource
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Times cited: 4070 -
Calmodulin is a subunit of nitric oxide synthase from macrophages.
The Journal of experimental medicine.
1992
Academic Article
GET IT
Times cited: 593 -
Mobilizable intracellular pool of p55 (type I) tumor necrosis factor receptors in human neutrophils.
Journal of leukocyte biology.
1992
Academic Article
GET IT
Times cited: 32 -
Interactions of bacterial lipopolysaccharide with microtubule proteins.
Journal of immunology (Baltimore, Md. : 1950).
1992
Academic Article
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Times cited: 53 -
Treatment of patients with chronic granulomatous disease with recombinant human interferon-gamma does not improve neutrophil oxidative metabolism, cytochrome b558 content or levels of four anti-microbial proteins.
Clinical and experimental immunology.
1992
Academic Article
GET IT
Times cited: 40 -
Cloning and characterization of inducible nitric oxide synthase from mouse macrophages.
Science (New York, N.Y.).
1992
Academic Article
GET IT
Times cited: 1709 -
Macrophage deactivation by interleukin 10.
The Journal of experimental medicine.
1991
Academic Article
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Times cited: 1198 -
Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils.
The Journal of biological chemistry.
1991
Academic Article
GET IT
Times cited: 186 -
Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.
The Journal of experimental medicine.
1991
Academic Article
GET IT
Times cited: 418 -
A commentary: inducible nitric oxide synthase.
Research in immunology.
1991
Academic Article
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Times cited: 4 -
Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
1991
Information Resource
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Times cited: 456 -
Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein.
Proceedings of the National Academy of Sciences of the United States of America.
1991
Academic Article
GET IT
Times cited: 776 -
Complementary DNA sequence of human neutrophil azurocidin, an antibiotic with extensive homology to serine proteases.
Biochemical and biophysical research communications.
1991
Academic Article
GET IT
Times cited: 43 -
Cytokines in context.
The Journal of cell biology.
1991
Information Resource
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Times cited: 753 -
N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine.
The Journal of biological chemistry.
1991
Academic Article
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Times cited: 488 -
Production of large amounts of hydrogen peroxide by human tumor cells.
Cancer research.
1991
Academic Article
GET IT
Times cited: 1984 -
Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
1991
Academic Article
GET IT
Times cited: 392 -
The mode of action and clinical pharmacology of gliclazide: a review.
Diabetes research and clinical practice.
1991
Review
GET IT
Times cited: 112 -
Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils.
The Journal of experimental medicine.
1990
Academic Article
GET IT
Times cited: 152 -
Tumor necrosis factor and CD11/CD18 (beta 2) integrins act synergistically to lower cAMP in human neutrophils.
The Journal of cell biology.
1990
Academic Article
GET IT
Times cited: 138 -
Widespread intradermal accumulation of mononuclear leukocytes in lepromatous leprosy patients treated systemically with recombinant interferon gamma.
The Journal of experimental medicine.
1990
Academic Article
GET IT
Times cited: 31 -
L-citrulline production from L-arginine by macrophage nitric oxide synthase. The ureido oxygen derives from dioxygen.
The Journal of biological chemistry.
1990
Academic Article
GET IT
Times cited: 204 -
Macrophage deactivating factor and transforming growth factors-beta 1 -beta 2 and -beta 3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950).
1990
Academic Article
GET IT
Times cited: 452 -
Shedding of tumor necrosis factor receptors by activated human neutrophils.
The Journal of experimental medicine.
1990
Academic Article
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Times cited: 418 -
Does endothelium-derived nitric oxide have a role in cytokine-induced hypotension?.
Journal of the National Cancer Institute.
1990
Comment
GET IT
Times cited: 69 -
FAD and GSH participate in macrophage synthesis of nitric oxide.
Biochemical and biophysical research communications.
1990
Academic Article
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Times cited: 152 -
Shared actions of endotoxin and taxol on TNF receptors and TNF release.
Science (New York, N.Y.).
1990
Academic Article
GET IT
Times cited: 275 -
Purification of macrophage deactivating factor.
The Journal of experimental medicine.
1990
Academic Article
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Times cited: 36 -
Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties.
The Journal of clinical investigation.
1990
Academic Article
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Times cited: 175 -
Downregulation of tumor necrosis factor receptors on macrophages and endothelial cells by microtubule depolymerizing agents.
The Journal of experimental medicine.
1990
Academic Article
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Times cited: 130 -
Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages.
The Journal of biological chemistry.
1989
Academic Article
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Times cited: 500 -
Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins.
The Journal of cell biology.
1989
Academic Article
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Times cited: 535 -
Adenosine regulates the respiratory burst of cytokine-triggered human neutrophils adherent to biologic surfaces.
Journal of immunology (Baltimore, Md. : 1950).
1989
Academic Article
GET IT
Times cited: 48 -
Antibiotic proteins of human polymorphonuclear leukocytes.
Proceedings of the National Academy of Sciences of the United States of America.
1989
Academic Article
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Times cited: 243 -
Synthesis of nitrogen oxides from L-arginine by macrophage cytosol: requirement for inducible and constitutive components.
Biochemical and biophysical research communications.
1989
Academic Article
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Times cited: 116 -
Comparison of transforming growth factor-beta and a macrophage- deactivating polypeptide from tumor cells. Differences in antigenicity and mechanism of action.
Journal of immunology (Baltimore, Md. : 1950).
1989
Academic Article
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Times cited: 31 -
Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.
The Journal of experimental medicine.
1989
Academic Article
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Times cited: 1714 -
Macrophages rapidly internalize their tumor necrosis factor receptors in response to bacterial lipopolysaccharide.
The Journal of biological chemistry.
1989
Academic Article
GET IT
Times cited: 92 -
Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.
The Journal of experimental medicine.
1989
Academic Article
GET IT
Times cited: 408 -
Fenfluramine studies.
Science (New York, N.Y.).
1989
Article
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Times cited: 14 - Patients' rights in a Third World southern African country, with special reference to Bophuthatswana: is there any potential for privatisation?. Medicine and law. 1989 Academic Article GET IT
-
Respiratory burst in adherent human neutrophils: triggering by colony-stimulating factors CSF-GM and CSF-G.
Blood.
1989
Academic Article
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Times cited: 221 -
In vivo killing of intracellular visceral Leishmania donovani by a macrophage-targeted hydrogen peroxide-generating system.
The Journal of infectious diseases.
1988
Academic Article
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Times cited: 10 -
Isolation of a complementary DNA clone encoding a precursor to human eosinophil major basic protein.
The Journal of experimental medicine.
1988
Academic Article
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Times cited: 49 -
The measurement of cytochrome b559 in polymorphonuclear leukocytes and macrophages in the presence of hemoglobin or mitochondrial cytochromes.
Analytical biochemistry.
1988
Academic Article
GET IT
Times cited: 12 -
Identification of arginine as a precursor of endothelium-derived relaxing factor.
Proceedings of the National Academy of Sciences of the United States of America.
1988
Academic Article
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Times cited: 404 -
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.
Journal of immunology (Baltimore, Md. : 1950).
1988
Academic Article
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Times cited: 2543 -
Deactivation of macrophages by transforming growth factor-beta.
Nature.
1988
Academic Article
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Times cited: 739 -
Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta.
The Journal of experimental medicine.
1988
Academic Article
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Times cited: 69 -
Analysis of the nonfunctional respiratory burst in murine Kupffer cells.
The Journal of experimental medicine.
1988
Academic Article
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Times cited: 25 -
Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.
The Journal of experimental medicine.
1988
Academic Article
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Times cited: 505 -
Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.
The Journal of clinical investigation.
1987
Academic Article
GET IT
Times cited: 761 -
Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma.
The Journal of experimental medicine.
1987
Academic Article
GET IT
Times cited: 209 -
In vitro susceptibility of nosocomial Pseudomonas aeruginosa, enterobacteriaceae, and staphylococci to ciprofloxacin and ten other broad-spectrum antibiotics.
Chemioterapia : international journal of the Mediterranean Society of Chemotherapy.
1987
Academic Article
GET IT
Times cited: 1 -
Trace levels of bacterial lipopolysaccharide prevent interferon-gamma or tumor necrosis factor-alpha from enhancing mouse peritoneal macrophage respiratory burst capacity.
Journal of immunology (Baltimore, Md. : 1950).
1987
Academic Article
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Times cited: 61 -
Cellular responses to the intradermal injection of recombinant human gamma-interferon in lepromatous leprosy patients.
The American journal of pathology.
1987
Academic Article
GET IT
Times cited: 63 -
Hydrogen peroxide release by alveolar macrophages from sarcoid patients and by alveolar macrophages from normals after exposure to recombinant interferons alpha A, beta, and gamma and 1,25-dihydroxyvitamin D3.
The Journal of clinical investigation.
1987
Academic Article
GET IT
Times cited: 63 -
Experimental visceral leishmaniasis: production of interleukin 2 and interferon-gamma, tissue immune reaction, and response to treatment with interleukin 2 and interferon-gamma.
Journal of immunology (Baltimore, Md. : 1950).
1987
Academic Article
GET IT
Times cited: 155 -
Activation of mouse peritoneal macrophages by monoclonal antibodies to Mac-1 (complement receptor type 3).
The Journal of experimental medicine.
1987
Academic Article
GET IT
Times cited: 45 -
Secretion of pyruvate. An antioxidant defense of mammalian cells.
The Journal of experimental medicine.
1987
Academic Article
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Times cited: 262 -
Secretory products of macrophages.
The Journal of clinical investigation.
1987
Information Resource
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Times cited: 2310 -
Subcellular location and properties of bactericidal factors from human neutrophils.
The Journal of experimental medicine.
1986
Academic Article
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Times cited: 43 -
Macrophage deactivation. Altered kinetic properties of superoxide-producing enzyme after exposure to tumor cell-conditioned medium.
The Journal of experimental medicine.
1986
Academic Article
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Times cited: 34 -
Release of arachidonate and reduction of oxygen. Independent metabolic bursts of the mouse peritoneal macrophage.
The Journal of biological chemistry.
1986
Academic Article
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Times cited: 41 -
Effects of reagent and cell-generated hydrogen peroxide on the properties of low density lipoprotein.
Proceedings of the National Academy of Sciences of the United States of America.
1986
Academic Article
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Times cited: 20 -
Effect of recombinant interferon-gamma on hydrogen peroxide-releasing capacity of monocyte-derived macrophages from patients with lepromatous leprosy.
Journal of immunology (Baltimore, Md. : 1950).
1986
Academic Article
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Times cited: 23 -
Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy.
The New England journal of medicine.
1986
Academic Article
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Times cited: 246 -
Phase I trial of recombinant interferon gamma by 1-hour i.v. infusion.
Cancer treatment reports.
1986
Academic Article
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Times cited: 35 - Phase I trial of recombinant interferon gamma in cancer patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1986 Academic Article GET IT
- Functional channel formation associated with cytotoxic T-cell granules. Proceedings of the National Academy of Sciences of the United States of America. 1986 Academic Article GET IT
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Peroxide and pteridine: a hypothesis on the regulation of macrophage antimicrobial activity by interferon gamma.
Interferon.
1986
Information Resource
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Times cited: 103 -
Secretion of toxic oxygen products by macrophages: regulatory cytokines and their effects on the oxidase.
Ciba Foundation symposium.
1986
Information Resource
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Times cited: 61 - Administration of recombinant interferon gamma to cancer patients enhances monocyte secretion of hydrogen peroxide. Proceedings of the National Academy of Sciences of the United States of America. 1985 Academic Article GET IT
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Hydrogen peroxide from cellular metabolism of cystine. A requirement for lysis of murine tumor cells by vernolepin, a glutathione-depleting antineoplastic.
The Journal of clinical investigation.
1985
Academic Article
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Times cited: 23 -
Resistance of human tumor cells in vitro to oxidative cytolysis.
The Journal of clinical investigation.
1985
Academic Article
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Times cited: 68 -
Liver macrophages in murine listeriosis. Cell-mediated immunity is correlated with an influx of macrophages capable of generating reactive oxygen intermediates.
The Journal of experimental medicine.
1985
Academic Article
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Times cited: 86 -
Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates.
The Journal of experimental medicine.
1985
Academic Article
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Times cited: 121 -
A semi-automated micro-assay for H2O2 release by human blood monocytes and mouse peritoneal macrophages.
Journal of immunological methods.
1985
Academic Article
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Times cited: 132 -
Salivary progesterone profile after in-vitro fertilisation/embryo transfer.
Lancet (London, England).
1985
Letter
GET IT
Times cited: 2 -
Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma.
Journal of immunology (Baltimore, Md. : 1950).
1985
Academic Article
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Times cited: 253 -
Relationship between extracellular stimulation of intracellular killing and oxygen-dependent microbicidal systems of monocytes.
Infection and immunity.
1985
Academic Article
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Times cited: 15 -
Biological activities of a human pluripotent hemopoietic colony-stimulating factor.
Haematology and blood transfusion.
1985
Academic Article
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Times cited: 4 - [Antenatal diagnosis and fetal surgery]. La Revue du praticien. 1984 Academic Article GET IT
- Epidemiology of endemic Pseudomonas aeruginosa: why infection control efforts have failed. The Journal of infectious diseases. 1984 Academic Article GET IT
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Association of infection caused by Pseudomonas aeruginosa serotype O11 with intravenous abuse of pentazocine mixed with tripelennamine.
Journal of clinical microbiology.
1984
Academic Article
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Times cited: 21 -
Activation of human macrophages. Comparison of other cytokines with interferon-gamma.
The Journal of experimental medicine.
1984
Academic Article
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Times cited: 313 -
Bacillus Calmette-Guérin-activated murine macrophages kill syngeneic melanoma cells under strict anaerobic conditions.
The Journal of experimental medicine.
1984
Academic Article
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Times cited: 13 -
Enzymatic basis of macrophage activation. Kinetic analysis of superoxide production in lysates of resident and activated mouse peritoneal macrophages and granulocytes.
The Journal of biological chemistry.
1984
Academic Article
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Times cited: 100 - Pseudomonas in the sinks in an intensive care unit: relation to patients. Journal of clinical pathology. 1984 Academic Article GET IT
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Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.
The Journal of experimental medicine.
1983
Academic Article
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Times cited: 1539 -
Suppression of macrophage antimicrobial activity by a tumor cell product.
Journal of immunology (Baltimore, Md. : 1950).
1983
Academic Article
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Times cited: 21 -
Inhibition of glutathione synthesis augments lysis of murine tumor cells by sulfhydryl-reactive antineoplastics.
The Journal of clinical investigation.
1983
Academic Article
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Times cited: 59 -
A simple method for counting adherent cells: application to cultured human monocytes, macrophages and multinucleated giant cells.
Journal of immunological methods.
1983
Academic Article
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Times cited: 131 -
Lymphokines enhance the capacity of human monocytes to secret reactive oxygen intermediates.
The Journal of clinical investigation.
1982
Academic Article
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Times cited: 68 -
Role of oxygen in T cell-mediated cytolysis.
Journal of immunology (Baltimore, Md. : 1950).
1982
Academic Article
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Times cited: 24 -
Suppression of macrophage oxidative metabolism by products of malignant and nonmalignant cells.
The Journal of experimental medicine.
1982
Academic Article
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Times cited: 59 -
Augmentation of spontaneous macrophage-mediated cytolysis by eosinophil peroxidase.
The Journal of experimental medicine.
1982
Academic Article
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Secretion of oxygen intermediates: role in effector functions of activated macrophages.
Federation proceedings.
1982
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Gentamicin-resistant staphylococci as hospital flora: epidemiology and resistance plasmids.
The Journal of infectious diseases.
1982
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Glutathione depletion sensitizes tumor cells to oxidative cytolysis.
The Journal of biological chemistry.
1982
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Antitumor effects of hydrogen peroxide in vivo.
The Journal of experimental medicine.
1981
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Hydrogen peroxide and cytolytic factor can interact synergistically in effecting cytolysis of neoplastic targets.
Journal of immunology (Baltimore, Md. : 1950).
1981
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Hydrogen peroxide metabolism in human monocytes during differentiation in vitro.
The Journal of clinical investigation.
1981
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Tumor cell anti-oxidant defenses. Inhibition of the glutathione redox cycle enhances macrophage-mediated cytolysis.
The Journal of experimental medicine.
1981
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Macrophage oxygen-dependent antimicrobial activity. IV. Role of endogenous scavengers of oxygen intermediates.
The Journal of experimental medicine.
1980
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Times cited: 47 - Role of activated macrophages in antibody-dependent lysis of tumor cells. The Journal of experimental medicine. 1980 Academic Article GET IT
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Role of oxygen-dependent mechanisms in antibody-induced lysis of tumor cells by activated macrophages.
The Journal of experimental medicine.
1980
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Times cited: 133 - Identity and interspecific transfer of gentamicin-resistance plasmids in Staphylococcus aureus and Staphylococcus epidermidis. The Journal of infectious diseases. 1980 Academic Article GET IT
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Endemic aminoglycoside resistance in gram-negative bacilli: epidemiology and mechanisms.
The Journal of infectious diseases.
1980
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Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates.
The Journal of experimental medicine.
1979
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Activation of macrophages in vivo and in vitro. Correlation between hydrogen peroxide release and killing of Trypanosoma cruzi.
The Journal of experimental medicine.
1979
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Times cited: 212 -
Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide.
The Journal of experimental medicine.
1979
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Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen peroxide as a mediator of cytotoxicity.
The Journal of experimental medicine.
1979
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In vitro activity of Sch 21420, derivative of gentamicin B, compared to that of amikacin.
Antimicrobial agents and chemotherapy.
1978
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Times cited: 10 - Infections due to gentamicin-resistant Staphylococcus aureus strain in a nursery for neonatal infants. Antimicrobial agents and chemotherapy. 1978 Academic Article GET IT
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Hydrogen peroxide release from mouse peritoneal macrophages: dependence on sequential activation and triggering.
The Journal of experimental medicine.
1977
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Characterization of the nonphagocytic adherent cell from the peritoneal cavity of normal and BCG-treated mice.
Journal of immunology (Baltimore, Md. : 1950).
1977
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Times cited: 48 -
Decreased phagocytosis by peritoneal macrophages from BCG-treated mice: induction of the phagocytic defect in normal macrophages with BCG in vitro.
Cellular immunology.
1977
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Times cited: 31 -
In vitro comparison of netilmicin, a semisynthetic derivative of sisomicin, and four other aminoglycoside antibiotics.
Antimicrobial agents and chemotherapy.
1976
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Isolation of a subpopulation of adherent peritoneal cells with anti-tumour activity.
Nature.
1976
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Differential stimulation of murine lymphoma growth in vitro by normal and BCG-activated macrophages.
The Journal of experimental medicine.
1975
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Cryptococcal osteomyelitis treated with 5-fluorocytosine.
The American review of respiratory disease.
1974
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Times cited: 16 -
Gentamicin-adenylyltransferase activity as a cause of gentamicin resistance in clinical isolates of Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy.
1974
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Times cited: 10 -
Characterization of a lymphocyte factor which alters macrophage functions.
The Journal of experimental medicine.
1973
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Physicochemical characteristics of several mediators from stimulated guinea pig and human lymphocytes.
Transplantation proceedings.
1972
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Alterations of macrophage functions by mediators from lymphocytes.
The Journal of experimental medicine.
1971
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Times cited: 338