Blobel, Carl P.

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selected publications

Development of a Proteomic Workflow for the Identification of Heparan Sulphate Proteoglycan-Binding Substrates of ADAM17. Proteomics. 2024 Academic Article GET IT
The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus. eLife. 2024 Academic Article GET IT
Endothelial cell sphingosine 1-phosphate receptor 1 restrains VE-cadherin cleavage and attenuates experimental inflammatory arthritis. JCI insight. 2024 Academic Article GET IT
Role of iRhom2 in Olfaction: Implications for Odorant Receptor Regulation and Activity-Dependent Adaptation. International journal of molecular sciences. 2024 Academic Article GET IT
iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I. Cellular and molecular life sciences : CMLS. 2024 Academic Article GET IT
Analysis of the function of ADAM17 in iRhom2 curly-bare and tylosis with esophageal cancer mutant mice. Journal of cell science. 2023 Academic Article GET IT
Identification of Molecular Determinants in iRhoms1 and 2 That Contribute to the Substrate Selectivity of Stimulated ADAM17. International journal of molecular sciences. 2022 Academic Article GET IT
Times cited: 6
ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion. EMBO reports. 2022 Academic Article GET IT
Times cited: 73
The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2021 Academic Article GET IT
Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype. The Journal of biological chemistry. 2021 Academic Article GET IT
Times cited: 7
Analysis of the Conditions That Affect the Selective Processing of Endogenous Notch1 by ADAM10 and ADAM17. International journal of molecular sciences. 2021 Academic Article GET IT
Times cited: 11
The Threshold Effect: Lipopolysaccharide-Induced Inflammatory Responses in Primary Macrophages Are Differentially Regulated in an iRhom2-Dependent Manner. Frontiers in cellular and infection microbiology. 2021 Academic Article GET IT
Times cited: 2
Role of iRhoms 1 and 2 in Endochondral Ossification. International journal of molecular sciences. 2020 Academic Article GET IT
Times cited: 6
Endothelial deletion of ADAM10, a key regulator of Notch signaling, causes impaired decidualization and reduced fertility in female mice. Angiogenesis. 2020 Academic Article GET IT
Times cited: 4
Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020 Academic Article GET IT
Times cited: 24
ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1). The Journal of biological chemistry. 2020 Academic Article GET IT
Times cited: 16
ADAM10 controls the differentiation of the coronary arterial endothelium. Angiogenesis. 2018 Academic Article GET IT
Times cited: 31
Intriguing Roles for Endothelial ADAM10/Notch Signaling in the Development of Organ-Specific Vascular Beds. Physiological reviews. 2018 Review GET IT
Times cited: 37
A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity. Science translational medicine. 2018 Academic Article GET IT
Times cited: 47
Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway. Blood. 2018 Academic Article GET IT
Times cited: 43
The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands. Journal of cellular physiology. 2018 Academic Article GET IT
Times cited: 17
iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling. The Journal of clinical investigation. 2018 Academic Article GET IT
Times cited: 70
The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2018 Academic Article GET IT
Times cited: 27
Glomerular endothelial cell maturation depends on ADAM10, a key regulator of Notch signaling. Angiogenesis. 2018 Academic Article GET IT
Times cited: 33
Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α-converting enzyme. The Journal of biological chemistry. 2018 Academic Article GET IT
Times cited: 25
Characterization of the catalytic properties of the membrane-anchored metalloproteinase ADAM9 in cell-based assays. The Biochemical journal. 2017 Academic Article GET IT
Times cited: 10
Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis. Journal of cell science. 2017 Academic Article GET IT
Times cited: 35
iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice. European journal of immunology. 2016 Academic Article GET IT
Times cited: 14
ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds. Circulation research. 2016 Academic Article GET IT
Times cited: 47
Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17. Science signaling. 2015 Academic Article GET IT
Times cited: 50
Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism. Arthritis research & therapy. 2015 Academic Article GET IT
Times cited: 18
iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling. Proceedings of the National Academy of Sciences of the United States of America. 2015 Academic Article GET IT
Times cited: 122
The Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site. The Journal of biological chemistry. 2015 Academic Article GET IT
Times cited: 65
The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding. The Journal of biological chemistry. 2015 Academic Article GET IT
Times cited: 34
iRhoms in the brain - a new frontier?. Cell cycle (Georgetown, Tex.). 2015 Editorial Article GET IT
Times cited: 14
Characterization of oxygen-induced retinopathy in mice carrying an inactivating point mutation in the catalytic site of ADAM15. Investigative ophthalmology & visual science. 2014 Academic Article GET IT
Times cited: 11
Phytochemicals perturb membranes and promiscuously alter protein function. ACS chemical biology. 2014 Academic Article GET IT
Times cited: 244
With blood in the joint - what happens next? Could activation of a pro-inflammatory signalling axis leading to iRhom2/TNFα-convertase-dependent release of TNFα contribute to haemophilic arthropathy?. Haemophilia : the official journal of the World Federation of Hemophilia. 2014 Information Resource GET IT
Times cited: 11
Lack of ADAM10 in endothelial cells affects osteoclasts at the chondro-osseus junction. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2013 Academic Article GET IT
Times cited: 11
A murine model for retinopathy of prematurity identifies endothelial cell proliferation as a potential mechanism for plus disease. Investigative ophthalmology & visual science. 2013 Academic Article GET IT
Times cited: 19
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding. Proceedings of the National Academy of Sciences of the United States of America. 2013 Academic Article GET IT
Times cited: 138
ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes. Molecular and cellular biology. 2013 Academic Article GET IT
Times cited: 49
ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins. The Biochemical journal. 2013 Academic Article GET IT
Times cited: 40
Epidermal ADAM17 is dispensable for notch activation. The Journal of investigative dermatology. 2013 Article GET IT
Times cited: 25
Intravitreal injection of TIMP3 or the EGFR inhibitor erlotinib offers protection from oxygen-induced retinopathy in mice. Investigative ophthalmology & visual science. 2013 Academic Article GET IT
Times cited: 29
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis. The Journal of clinical investigation. 2013 Academic Article GET IT
Times cited: 143
Stromal fibroblast-specific expression of ADAM-9 modulates proliferation and apoptosis in melanoma cells in vitro and in vivo. The Journal of investigative dermatology. 2012 Academic Article GET IT
Times cited: 15
Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. Nature immunology. 2012 Academic Article GET IT
Times cited: 359
Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation. The Journal of experimental medicine. 2012 Academic Article GET IT
Times cited: 158
Interleukin-1 stimulates ADAM17 through a mechanism independent of its cytoplasmic domain or phosphorylation at threonine 735. PloS one. 2012 Academic Article GET IT
Times cited: 41
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS. Science (New York, N.Y.). 2012 Academic Article GET IT
Times cited: 275
Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK). The Journal of biological chemistry. 2011 Academic Article GET IT
Times cited: 233
Lack of ADAM15 in mice is associated with increased osteoblast function and bone mass. Biological chemistry. 2011 Academic Article GET IT
Times cited: 9
Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation. The Journal of biological chemistry. 2011 Academic Article GET IT
Times cited: 90
TACE (ADAM17) inhibits Schwann cell myelination. Nature neuroscience. 2011 Academic Article GET IT
Times cited: 122
Deletion of Adam10 in endothelial cells leads to defects in organ-specific vascular structures. Blood. 2011 Academic Article GET IT
Times cited: 70
The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling. Development (Cambridge, England). 2011 Academic Article GET IT
Times cited: 134
Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17. Nature communications. 2011 Academic Article GET IT
Times cited: 125
TNF-α-converting enzyme/a disintegrin and metalloprotease-17 mediates mechanotransduction in murine tracheal epithelial cells. American journal of respiratory cell and molecular biology. 2010 Academic Article GET IT
Times cited: 24
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands. Proceedings of the National Academy of Sciences of the United States of America. 2010 Academic Article GET IT
Times cited: 133
ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site. Journal of cell science. 2010 Academic Article GET IT
Times cited: 166
A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17. Oncogene. 2010 Academic Article GET IT
Times cited: 52
Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice. The Journal of clinical investigation. 2010 Academic Article GET IT
Times cited: 78
3D trumps 2D when studying endothelial cells. Blood. 2010 Article GET IT
Times cited: 9
Stimulation of platelet-derived growth factor receptor beta (PDGFRbeta) activates ADAM17 and promotes metalloproteinase-dependent cross-talk between the PDGFRbeta and epidermal growth factor receptor (EGFR) signaling pathways. The Journal of biological chemistry. 2010 Academic Article GET IT
Times cited: 45
The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2010 Academic Article GET IT
Times cited: 308
The waved with open eyelids (woe) locus is a hypomorphic mouse mutation in Adam17. Genetics. 2010 Academic Article GET IT
Times cited: 39
ADAM8 is a negative regulator of retinal neovascularization and of the growth of heterotopically injected tumor cells in mice. Journal of molecular medicine (Berlin, Germany). 2010 Academic Article GET IT
Times cited: 50
Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytes. Circulation research. 2010 Academic Article GET IT
Times cited: 127
Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9. The Journal of biological chemistry. 2009 Academic Article GET IT
Times cited: 84
Ectodomain shedding of FLT3 ligand is mediated by TNF-alpha converting enzyme. Journal of immunology (Baltimore, Md. : 1950). 2009 Academic Article GET IT
Times cited: 30
Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer. Cancer research. 2009 Academic Article GET IT
Times cited: 25
Loss of the metalloprotease ADAM9 leads to cone-rod dystrophy in humans and retinal degeneration in mice. American journal of human genetics. 2009 Academic Article GET IT
Times cited: 67
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays. The Biochemical journal. 2009 Academic Article GET IT
Times cited: 42
ADAM9 is involved in pathological retinal neovascularization. Molecular and cellular biology. 2009 Academic Article GET IT
Times cited: 81
Conditional inactivation of TACE by a Sox9 promoter leads to osteoporosis and increased granulopoiesis via dysregulation of IL-17 and G-CSF. Journal of immunology (Baltimore, Md. : 1950). 2009 Academic Article GET IT
Times cited: 55
ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha. Molecular biology of the cell. 2009 Academic Article GET IT
Times cited: 189
Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae. Molecular biology of the cell. 2009 Academic Article GET IT
Times cited: 30
The role of protease activity in ErbB biology. Experimental cell research. 2008 Information Resource GET IT
Times cited: 73
VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling. Circulation research. 2008 Academic Article GET IT
Times cited: 144
ADAM12: a potential target for the treatment of chronic wounds. Journal of molecular medicine (Berlin, Germany). 2008 Academic Article GET IT
Times cited: 49
ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin. Circulation research. 2008 Academic Article GET IT
Times cited: 250
Cell surface colony-stimulating factor 1 can be cleaved by TNF-alpha converting enzyme or endocytosed in a clathrin-dependent manner. Journal of immunology (Baltimore, Md. : 1950). 2007 Academic Article GET IT
Times cited: 38
Cutting edge: TNF-alpha-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock. Journal of immunology (Baltimore, Md. : 1950). 2007 Academic Article GET IT
Times cited: 237
A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells. The Journal of biological chemistry. 2007 Academic Article GET IT
Times cited: 84
Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19. Journal of cell science. 2007 Academic Article GET IT
Times cited: 49
In search of partners: linking extracellular proteases to substrates. Nature reviews. Molecular cell biology. 2007 Information Resource GET IT
Times cited: 270
Metalloproteases regulate T-cell proliferation and effector function via LAG-3. The EMBO journal. 2007 Academic Article GET IT
Times cited: 218
Ectodomain shedding of the EGF-receptor ligand epigen is mediated by ADAM17. FEBS letters. 2006 Academic Article GET IT
Times cited: 88
Proteolytic processing of delta-like 1 by ADAM proteases. The Journal of biological chemistry. 2006 Academic Article GET IT
Times cited: 113
Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx. Molecular biology of the cell. 2006 Academic Article GET IT
Times cited: 271
ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23. Nature immunology. 2006 Academic Article GET IT
Times cited: 167
ADAM12 is highly expressed in carcinoma-associated stroma and is required for mouse prostate tumor progression. Oncogene. 2006 Academic Article GET IT
Times cited: 83
A sensitive method to monitor ectodomain shedding of ligands of the epidermal growth factor receptor. Methods in molecular biology (Clifton, N.J.). 2006 Academic Article GET IT
Times cited: 43
Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell. 2005 Academic Article GET IT
Times cited: 344
Critical function for ADAM9 in mouse prostate cancer. Cancer research. 2005 Academic Article GET IT
Times cited: 92
L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth. Molecular and cellular biology. 2005 Academic Article GET IT
Times cited: 206
Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2. Developmental biology. 2005 Academic Article GET IT
Times cited: 132
Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling. Arthritis and rheumatism. 2005 Academic Article GET IT
Times cited: 51
ADAMs: key components in EGFR signalling and development. Nature reviews. Molecular cell biology. 2005 Information Resource GET IT
Times cited: 843
Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice. Developmental dynamics : an official publication of the American Association of Anatomists. 2005 Academic Article GET IT
Times cited: 92
Evaluation of the contribution of different ADAMs to tumor necrosis factor alpha (TNFalpha) shedding and of the function of the TNFalpha ectodomain in ensuring selective stimulated shedding by the TNFalpha convertase (TACE/ADAM17). The Journal of biological chemistry. 2004 Academic Article GET IT
Times cited: 136
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. The Journal of cell biology. 2004 Academic Article GET IT
Times cited: 838
Essential role for ADAM19 in cardiovascular morphogenesis. Molecular and cellular biology. 2004 Academic Article GET IT
Times cited: 114
Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR). The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 120
Potential role for ADAM15 in pathological neovascularization in mice. Molecular and cellular biology. 2003 Academic Article GET IT
Times cited: 159
Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17). The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 195
Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain shedding. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 37
Catalytic properties of ADAM19. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 105
Biochemical properties and functions of membrane-anchored metalloprotease-disintegrin proteins (ADAMs). Current topics in developmental biology. 2003 Information Resource GET IT
Times cited: 85
Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 157
Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 95
The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. FEBS letters. 2002 Academic Article GET IT
Times cited: 125
Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life. Molecular and cellular biology. 2002 Academic Article GET IT
Times cited: 179
Highly enhanced expression of the disintegrin metalloproteinase MDC15 (metargidin) in rheumatoid synovial tissue. Arthritis and rheumatism. 2001 Academic Article GET IT
Times cited: 31
Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1). The Journal of biological chemistry. 2001 Academic Article GET IT
Times cited: 478
Catalytic activity of ADAM28. FEBS letters. 2001 Academic Article GET IT
Times cited: 62
Biochemical and pharmacological criteria define two shedding activities for TRANCE/OPGL that are distinct from the tumor necrosis factor alpha convertase. The Journal of biological chemistry. 2001 Academic Article GET IT
Times cited: 115
Remarkable roles of proteolysis on and beyond the cell surface. Current opinion in cell biology. 2000 Information Resource GET IT
Times cited: 221
Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28. The Biochemical journal. 2000 Academic Article GET IT
Times cited: 109
Functional processing of fertilin: evidence for a critical role of proteolysis in sperm maturation and activation. Reviews of reproduction. 2000 Information Resource GET IT
Times cited: 55
Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE). The Biochemical journal. 2000 Academic Article GET IT
Times cited: 321
Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta. The Biochemical journal. 1999 Academic Article GET IT
Times cited: 79
Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1. The Journal of biological chemistry. 1999 Academic Article GET IT
Times cited: 150
Up-regulation of MDC15 (metargidin) messenger RNA in human osteoarthritic cartilage. Arthritis and rheumatism. 1999 Academic Article GET IT
Times cited: 37
Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival. The Journal of biological chemistry. 1999 Academic Article GET IT
Times cited: 352
Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. The Journal of biological chemistry. 1999 Academic Article GET IT
Times cited: 266
Neural crest-specific and general expression of distinct metalloprotease-disintegrins in early Xenopus laevis development. Developmental biology. 1998 Academic Article GET IT
Times cited: 31
Intracellular maturation of the mouse metalloprotease disintegrin MDC15. The Journal of biological chemistry. 1998 Academic Article GET IT
Times cited: 132
Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells. The Journal of biological chemistry. 1998 Academic Article GET IT
Times cited: 94
Evidence for distinct serine protease activities with a potential role in processing the sperm protein fertilin. Developmental biology. 1997 Academic Article GET IT
Times cited: 88
Metalloprotease-disintegrins: links to cell adhesion and cleavage of TNF alpha and Notch. Cell. 1997 Information Resource GET IT
Times cited: 327
Identification of metalloprotease/disintegrins in Xenopus laevis testis with a potential role in fertilization. Developmental biology. 1997 Academic Article GET IT
Times cited: 67
AM67, a secretory component of the guinea pig sperm acrosomal matrix, is related to mouse sperm protein sp56 and the complement component 4-binding proteins. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 118
Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence. The Journal of biological chemistry. 1996 Academic Article GET IT
Times cited: 149
MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains. The Journal of cell biology. 1996 Academic Article GET IT
Times cited: 188
Apexin, an acrosomal pentaxin. The Journal of biological chemistry. 1994 Academic Article GET IT
Times cited: 68
Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion. Proceedings of the National Academy of Sciences of the United States of America. 1994 Academic Article GET IT
Times cited: 237
A family of cellular proteins related to snake venom disintegrins. Proceedings of the National Academy of Sciences of the United States of America. 1994 Academic Article GET IT
Times cited: 78
The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications. Proceedings of the National Academy of Sciences of the United States of America. 1993 Academic Article GET IT
Times cited: 167
A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion. Nature. 1992 Academic Article GET IT
Times cited: 602
Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence. The Journal of cell biology. 1990 Academic Article GET IT
Times cited: 206

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Background

education and training

Ph.D., University of California, San Francisco 91
M.D., Justus-Liebig University Faculty of Medicine (Germany) 1984

Contact

full name

Carl P. Blobel

primary email

blobelc@hss.edu

VIVO Weill Cornell Medical College

Carl P. Blobel Professor of Physiology in Medicine

Publications

selected publications

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Background

education and training

Contact

full name

primary email