selected publications
- Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression. Nature cancer. 2024 Academic Article GET IT
- MAP kinase kinase 1 (MEK1) within extracellular vesicles inhibits tumour growth by promoting anti-tumour immunity. Journal of extracellular vesicles. 2024 Academic Article GET IT
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Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.
Nature medicine.
2024
Academic Article
GET IT
Times cited: 4 -
Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA).
Nature communications.
2024
Academic Article
GET IT
Times cited: 14 - Molecular and physiologic changes in the SpaceX Inspiration4 civilian crew. Nature. 2024 Academic Article GET IT
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Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight.
Nature communications.
2024
Academic Article
GET IT
Times cited: 17 - The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. Nature. 2024 Academic Article GET IT
- Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load. Cell reports. 2024 Academic Article GET IT
- Tumour-derived Extracellular Vesicle and Particle Reprogramming of Interstitial Macrophages in the Lung Pre-Metastatic Niche Enhances Vascular Permeability and Metastatic Potential. 2024 GET IT
- Protocol for cross-platform characterization of human and murine extracellular vesicles and particles. STAR protocols. 2023 Academic Article GET IT
- Breast adipose tissue-derived extracellular vesicles from obese women alter tumor cell metabolism. EMBO reports. 2023 Academic Article GET IT
- Advancement in Cellular Topographic and Nanoparticle Capture Imaging by High Resolution Microscopy Incorporating a Freeze-Drying and Gaseous Nitrogen-based Approach. 2023 GET IT
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Extracellular vesicles and particles as mediators of long-range communication in cancer: connecting biological function to clinical applications.
Extracellular vesicles and circulating nucleic acids.
2023
Academic Article
GET IT
Times cited: 11 -
Updates on radiotherapy-immunotherapy combinations: Proceedings of 6th annual ImmunoRad conference.
Oncoimmunology.
2023
Review
GET IT
Times cited: 2 -
Tumour extracellular vesicles and particles induce liver metabolic dysfunction.
Nature.
2023
Academic Article
GET IT
Times cited: 80 - Tumor-derived nanoseeds condition the soil for metastatic organotropism. Seminars in cancer biology. 2023 Review GET IT
- The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche. Journal of extracellular vesicles. 2023 Academic Article GET IT
- Genomic mapping of metastatic organotropism in lung adenocarcinoma. Cancer cell. 2023 Academic Article GET IT
- Immune determinants of the pre-metastatic niche. Cancer cell. 2023 Review GET IT
- Protocol for Plasma Extracellular Vesicle and Particle Isolation and Mass Spectrometry-Based Proteomic Identification. Methods in molecular biology (Clifton, N.J.). 2023 Academic Article GET IT
- Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer. Frontiers in oncology. 2022 Academic Article GET IT
- BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling. Nature communications. 2022 Academic Article GET IT
- Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression. Nature communications. 2022 Academic Article GET IT
- Extracellular vesicles and particles impact the systemic landscape of cancer. The EMBO journal. 2022 Review GET IT
- ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance. NPJ breast cancer. 2022 Academic Article GET IT
- Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems. Clinical & experimental metastasis. 2022 Academic Article GET IT
- Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain. Nature cancer. 2021 Academic Article GET IT
- Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism. Nature cancer. 2021 Academic Article GET IT
- Calcium signaling induces a partial EMT. EMBO reports. 2021 Academic Article GET IT
- Extracellular vesicle- and particle-mediated communication shapes innate and adaptive immune responses. The Journal of experimental medicine. 2021 Information Resource GET IT
- The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings. Molecular oncology. 2021 Academic Article GET IT
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KRAS G12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2021
Academic Article
GET IT
Times cited: 24 -
A Genomic-Pathologic Annotated Risk Model to Predict Recurrence in Early-Stage Lung Adenocarcinoma.
JAMA surgery.
2021
Academic Article
GET IT
Times cited: 64 -
Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles.
Cancer research.
2021
Academic Article
GET IT
Times cited: 63 - Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids. STAR protocols. 2020 Academic Article GET IT
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Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers.
iScience.
2020
Academic Article
GET IT
Times cited: 37 -
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
Cell.
2020
Academic Article
GET IT
Times cited: 775 -
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
Cell stem cell.
2020
Academic Article
GET IT
Times cited: 498 -
Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases.
Future oncology (London, England).
2020
Academic Article
GET IT
Times cited: 26 -
Non-reversible tissue fixation retains extracellular vesicles for in situ imaging.
Nature methods.
2019
Academic Article
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Times cited: 16 -
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis.
Nature cell biology.
2019
Academic Article
GET IT
Times cited: 279 -
Tumor Lymphatic Function Regulates Tumor Inflammatory and Immunosuppressive Microenvironments.
Cancer immunology research.
2019
Academic Article
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Times cited: 37 -
Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease.
Nature communications.
2019
Academic Article
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Times cited: 138 -
Exosome-Mediated Metastasis: Communication from a Distance.
Developmental cell.
2019
Information Resource
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Times cited: 239 -
Asymmetric-flow field-flow fractionation technology for exomere and small extracellular vesicle separation and characterization.
Nature protocols.
2019
Academic Article
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Times cited: 317 -
Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer.
PloS one.
2018
Academic Article
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Times cited: 18 -
Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression.
Science advances.
2018
Academic Article
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Times cited: 155 -
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.
Nature cell biology.
2018
Academic Article
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Times cited: 1185 -
Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer.
HPB : the official journal of the International Hepato Pancreato Biliary Association.
2018
Academic Article
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Times cited: 54 -
Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer.
Proceedings of the National Academy of Sciences of the United States of America.
2017
Academic Article
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Times cited: 535 -
A phase II study of radioimmunotherapy with intraventricular 131 I-3F8 for medulloblastoma.
Pediatric blood & cancer.
2017
Academic Article
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Times cited: 51 -
Novel activating BRAF fusion identifies a recurrent alternative mechanism for ERK activation in pediatric Langerhans cell histiocytosis.
Pediatric blood & cancer.
2017
Academic Article
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Times cited: 15 -
Metastasis: Lymphatic detours for cancer.
Nature.
2017
Article
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Times cited: 5 -
A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors.
PloS one.
2017
Academic Article
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Times cited: 33 -
A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma.
The Journal of clinical investigation.
2017
Academic Article
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Times cited: 31 -
Pre-metastatic niches: organ-specific homes for metastases.
Nature reviews. Cancer.
2017
Information Resource
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Times cited: 624 -
Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles.
Cancer research.
2017
Academic Article
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Times cited: 118 -
A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.
Pediatric blood & cancer.
2016
Academic Article
GET IT
Times cited: 34 -
Malignant Astrocytic Tumor Progression Potentiated by JAK-mediated Recruitment of Myeloid Cells.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
Academic Article
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Times cited: 23 -
Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis.
Cancer cell.
2016
Information Resource
GET IT
Times cited: 1444 - The Effect of Cage Shape on Nanoparticle-Based Drug Carriers: Anticancer Drug Release and Efficacy via Receptor Blockade Using Dextran-Coated Iron Oxide Nanocages. Nano letters. 2016 Academic Article GET IT
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JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors.
Science signaling.
2016
Academic Article
GET IT
Times cited: 57 -
Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.
The Lancet. Oncology.
2016
Academic Article
GET IT
Times cited: 270 -
Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer.
Nature communications.
2016
Academic Article
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Times cited: 143 -
Divergent clonal selection dominates medulloblastoma at recurrence.
Nature.
2016
Academic Article
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Times cited: 254 -
Cancer Exosomes as Mediators of Drug Resistance.
Methods in molecular biology (Clifton, N.J.).
2016
Article
GET IT
Times cited: 12 -
Activation of Hematopoietic Stem/Progenitor Cells Promotes Immunosuppression Within the Pre-metastatic Niche.
Cancer research.
2015
Academic Article
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Times cited: 117 -
Tumour exosome integrins determine organotropic metastasis.
Nature.
2015
Academic Article
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Times cited: 3754 -
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nature cell biology.
2015
Academic Article
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Times cited: 2061 -
Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation.
Nature communications.
2015
Academic Article
GET IT
Times cited: 88 -
Efficacy and safety of CDX-301, recombinant human Flt3L, at expanding dendritic cells and hematopoietic stem cells in healthy human volunteers.
Bone marrow transplantation.
2015
Academic Article
GET IT
Times cited: 83 -
Medulloblastoma subgroups remain stable across primary and metastatic compartments.
Acta neuropathologica.
2015
Academic Article
GET IT
Times cited: 77 -
Double-stranded DNA in exosomes: a novel biomarker in cancer detection.
Cell research.
2014
Article
GET IT
Times cited: 1314 -
Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization.
Oncogene.
2014
Academic Article
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Times cited: 59 -
Macromolecular crowding meets tissue engineering by self-assembly: a paradigm shift in regenerative medicine.
Advanced materials (Deerfield Beach, Fla.).
2014
Academic Article
GET IT
Times cited: 102 -
Oligodendrocyte progenitor cells promote neovascularization in glioma by disrupting the blood-brain barrier.
Cancer research.
2013
Academic Article
GET IT
Times cited: 29 - The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis. Neoplasia (New York, N.Y.). 2013 Academic Article GET IT
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The evolution of the cancer niche during multistage carcinogenesis.
Nature reviews. Cancer.
2013
Information Resource
GET IT
Times cited: 178 -
The perivascular niche regulates breast tumour dormancy.
Nature cell biology.
2013
Academic Article
GET IT
Times cited: 880 -
Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes.
Molecular biology of the cell.
2013
Academic Article
GET IT
Times cited: 85 -
Molecular diagnostics in paediatric glial tumours.
The Lancet. Oncology.
2013
Information Resource
GET IT
Times cited: 8 -
STAT3 negatively regulates thyroid tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
GET IT
Times cited: 114 -
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Nature medicine.
2012
Academic Article
GET IT
Times cited: 3004 -
Megakaryocytes, malignancy and bone marrow vascular niches.
Journal of thrombosis and haemostasis : JTH.
2012
Information Resource
GET IT
Times cited: 56 -
Stat3 mediates expression of autotaxin in breast cancer.
PloS one.
2011
Academic Article
GET IT
Times cited: 67 -
A TeNaCious foundation for the metastatic niche.
Cancer cell.
2011
Article
GET IT
Times cited: 5 -
Disease control and ototoxicity using intensity-modulated radiation therapy tumor-bed boost for medulloblastoma.
International journal of radiation oncology, biology, physics.
2011
Academic Article
GET IT
Times cited: 39 -
The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.
Seminars in cancer biology.
2011
Information Resource
GET IT
Times cited: 442 -
Neoangiogenesis contributes to the development of hemophilic synovitis.
Blood.
2010
Academic Article
GET IT
Times cited: 103 -
Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration.
Nature.
2010
Academic Article
GET IT
Times cited: 663 -
Intensive multimodality therapy for patients with stage 4a metastatic retinoblastoma.
Pediatric blood & cancer.
2010
Academic Article
GET IT
Times cited: 48 -
Resisting arrest: a switch from angiogenesis to vasculogenesis in recurrent malignant gliomas.
The Journal of clinical investigation.
2010
Article
GET IT
Times cited: 31 -
Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent.
Nature biotechnology.
2010
Academic Article
GET IT
Times cited: 267 -
Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.
PloS one.
2009
Academic Article
GET IT
Times cited: 29 -
Gene therapy in skin: choosing the optimal viral vector.
Annals of plastic surgery.
2009
Academic Article
GET IT
Times cited: 5 -
The metastatic niche: adapting the foreign soil.
Nature reviews. Cancer.
2009
Information Resource
GET IT
Times cited: 1043 -
Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas.
Proceedings of the National Academy of Sciences of the United States of America.
2008
Article
GET IT
Times cited: 50 -
CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors.
The Journal of clinical investigation.
2008
Academic Article
GET IT
Times cited: 816 -
A catalytic role for proangiogenic marrow-derived cells in tumor neovascularization.
Cancer cell.
2008
Comment
GET IT
Times cited: 73 -
Migratory neighbors and distant invaders: tumor-associated niche cells.
Genes & development.
2008
Information Resource
GET IT
Times cited: 330 -
Regulation of vasculogenesis by platelet-mediated recruitment of bone marrow-derived cells.
Arteriosclerosis, thrombosis, and vascular biology.
2007
Review
GET IT
Times cited: 53 -
A phase II trial of carboplatin for intraocular retinoblastoma.
Pediatric blood & cancer.
2007
Academic Article
GET IT
Times cited: 37 -
A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignancies.
Pediatric blood & cancer.
2007
Academic Article
GET IT
Times cited: 13 -
Niche-to-niche migration of bone-marrow-derived cells.
Trends in molecular medicine.
2007
Information Resource
GET IT
Times cited: 178 -
Bone marrow cells in the 'pre-metastatic niche': within bone and beyond.
Cancer metastasis reviews.
2006
Information Resource
GET IT
Times cited: 240 -
Preparing the "soil": the premetastatic niche.
Cancer research.
2006
Information Resource
GET IT
Times cited: 538 -
Treatment-related myelodysplastic syndrome after chemotherapy for childhood low-grade astrocytoma.
Journal of pediatric hematology/oncology.
2006
Article
GET IT
Times cited: 1 -
Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes.
Nature medicine.
2006
Academic Article
GET IT
Times cited: 579 -
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche.
Nature.
2005
Academic Article
GET IT
Times cited: 2710 -
p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow.
Proceedings of the National Academy of Sciences of the United States of America.
2005
Academic Article
GET IT
Times cited: 18 -
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis.
Nature medicine.
2003
Academic Article
GET IT
Times cited: 598 -
Patterns of failure using a conformal radiation therapy tumor bed boost for medulloblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2003
Academic Article
GET IT
Times cited: 80 -
Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration.
Nature medicine.
2003
Information Resource
GET IT
Times cited: 1407 -
Tumor response to radiotherapy regulated by endothelial cell apoptosis.
Science (New York, N.Y.).
2003
Academic Article
GET IT
Times cited: 1230 -
Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?.
Nature reviews. Cancer.
2002
Information Resource
GET IT
Times cited: 602 -
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment.
Nature medicine.
2002
Academic Article
GET IT
Times cited: 566 -
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand.
Cell.
2002
Academic Article
GET IT
Times cited: 1551 -
Young adult bone marrow-derived endothelial precursor cells restore aging-impaired cardiac angiogenic function.
Circulation research.
2002
Academic Article
GET IT
Times cited: 277 -
The Id proteins and angiogenesis.
Oncogene.
2001
Information Resource
GET IT
Times cited: 190 -
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth.
Nature medicine.
2001
Academic Article
GET IT
Times cited: 1638 -
Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells.
The Journal of experimental medicine.
2001
Academic Article
GET IT
Times cited: 622 -
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts.
Nature.
1999
Academic Article
GET IT
Times cited: 752 - Intensive chemotherapy and bone marrow rescue for young children with newly diagnosed malignant brain tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1998 Academic Article GET IT
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The expanding role of chemotherapy for pediatric supratentorial malignant gliomas.
Journal of neuro-oncology.
1996
Information Resource
GET IT
Times cited: 3 -
Variation in susceptibility of Balb/c mice to coxsackievirus group B type 3-induced myocarditis with age.
Cellular immunology.
1987
Academic Article
GET IT
Times cited: 21 -
Coxsackievirus B-3-induced myocarditis. Effect of sex steroids on viremia and infectivity of cardiocytes.
The American journal of pathology.
1987
Academic Article
GET IT
Times cited: 86 -
Demonstration of suppressor cells in coxsackievirus group B, type 3 infected female Balb/c mice which prevent myocarditis.
Cellular immunology.
1986
Academic Article
GET IT
Times cited: 9 -
Immunopathogenesis of experimental Coxsackievirus induced myocarditis: role of autoimmunity.
Herz.
1985
Academic Article
GET IT
Times cited: 16 -
Aggravation of coxsackievirus, group B, type 3-induced myocarditis and increase in cellular immunity to myocyte antigens in pregnant Balb/c mice and animals treated with progesterone.
Cellular immunology.
1984
Academic Article
GET IT
Times cited: 42