Nixon, Douglas

Publications

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selected publications

EBV Triggers a Distinct Antiviral Response in HMC3 Cells. bioRxiv : the preprint server for biology. 2026 Article GET IT
HIV Nef-mediated WAVE2-ARP2/3 inhibition underlies CD4⁺ T-cell lamellipodial abnormalities and immune dysfunction. mBio. 2026 Academic Article GET IT
Human endogenous retrovirus profiling reveals heterogenous expression in cutaneous melanoma. Frontiers in oncology. 2026 Academic Article GET IT
Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound. Immunity. 2026 Academic Article GET IT
CDK9 Inhibition with enitociclib reveals influence on HERV and LINE RNA abundances in whole blood, T-, and B-Cell lines. BMC medical genomics. 2026 Academic Article GET IT
Transcriptional signature of induced neurons differentiates virologically suppressed people with HIV from people without HIV. JCI insight. 2025 Academic Article GET IT
A single-cell transposable element atlas of human cell identity. Cell reports methods. 2025 Academic Article GET IT
Times cited: 4
Locus-specific human endogenous retroviruses reveal lymphoma subtypes. iScience. 2025 Academic Article GET IT
Times cited: 2
The five senses of immunity. Trends in immunology. 2025 Academic Article GET IT
Times cited: 1
Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model. Journal of neuroinflammation. 2025 Academic Article GET IT
Times cited: 9
Transposable elements may enhance antiviral resistance in HIV-1 elite controllers. Genome biology. 2025 Academic Article GET IT
Times cited: 7
Distinct Tissue-Dependent Composition and Gene Expression of Human Fetal Innate Lymphoid Cells. European journal of immunology. 2024 Academic Article GET IT
Endogenous retroelement expression in modeled airway epithelial repair. Microbes and infection. 2024 Academic Article GET IT
Times cited: 3
A model of proximate protection against pathogenic infection through shared immunity. mBio. 2024 Academic Article GET IT
Times cited: 2
A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIV. bioRxiv : the preprint server for biology. 2024 Article GET IT
Ancient viral DNA in the human genome linked to neurodegenerative diseases. Brain, behavior, and immunity. 2024 Academic Article GET IT
Times cited: 4
Silencing the transcriptionally active HIV reservoir to improve treatment outcomes. Nature microbiology. 2024 Academic Article GET IT
Times cited: 7
Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements. Aging cell. 2024 Academic Article GET IT
Times cited: 17
Integrating human endogenous retroviruses into transcriptome-wide association studies highlights novel risk factors for major psychiatric conditions. Nature communications. 2024 Academic Article GET IT
Times cited: 20
Endogenous retroelement expression in the gut microenvironment of people living with HIV-1. EBioMedicine. 2024 Academic Article GET IT
Times cited: 8
Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques. Science (New York, N.Y.). 2024 Academic Article GET IT
Times cited: 19
HIV-1 Mediated Cortical Actin Disruption Mirrors ARP2/3 Defects Found in Primary T Cell Immunodeficiencies. bioRxiv : the preprint server for biology. 2024 Article GET IT
Ribosomal profiling of human endogenous retroviruses in healthy tissues. BMC genomics. 2024 Information Resource GET IT
Times cited: 9
A single-cell transposable element atlas of human cell identity. bioRxiv : the preprint server for biology. 2023 Article GET IT
The brain-liver cholinergic anti-inflammatory pathway and viral infections. Bioelectronic medicine. 2023 Information Resource GET IT
Times cited: 4
Transposable elements may enhance antiviral resistance in HIV-1 elite controllers. bioRxiv : the preprint server for biology. 2023 Article GET IT
Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states. bioRxiv : the preprint server for biology. 2023 Article GET IT
HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing. Viruses. 2023 Academic Article GET IT
Times cited: 11
Activation of human endogenous retroviruses and its physiological consequences. Nature reviews. Molecular cell biology. 2023 Information Resource GET IT
Times cited: 80
A History and Atlas of the Human CD4⁺ T Helper Cell. Biomedicines. 2023 Information Resource GET IT
Times cited: 1
Locus specific human endogenous retroviruses reveal new lymphoma subtypes. bioRxiv : the preprint server for biology. 2023 Article GET IT
Times cited: 3884
Endogenous Reverse Transcriptase Inhibition Attenuates TLR5-Mediated Inflammation. mBio. 2023 Academic Article GET IT
Times cited: 7
Transposable elements and Alzheimer's disease pathogenesis. Trends in neurosciences. 2022 Academic Article GET IT
Times cited: 30
HIV-1 replication and latency are balanced by mTOR-driven cell metabolism. Frontiers in cellular and infection microbiology. 2022 Information Resource GET IT
Times cited: 30
Off-Target Effect of Activation of NF-κB by HIV Latency Reversal Agents on Transposable Elements Expression. Viruses. 2022 Academic Article GET IT
Times cited: 8
Heterologous vaccination interventions to reduce pandemic morbidity and mortality: Modeling the US winter 2020 COVID-19 wave. Proceedings of the National Academy of Sciences of the United States of America. 2022 Academic Article GET IT
Times cited: 21
Restriction of HIV-1 infection in sickle cell trait. Blood advances. 2021 Academic Article GET IT
Times cited: 3
Lithium treatment and human hippocampal neurogenesis. Translational psychiatry. 2021 Academic Article GET IT
Times cited: 36
Extreme immunotherapy: emergency immunology to defeat pandemics. Molecular medicine (Cambridge, Mass.). 2021 Academic Article GET IT
Locus-Specific Characterization of Human Endogenous Retrovirus Expression in Prostate, Breast, and Colon Cancers. Cancer research. 2021 Academic Article GET IT
Times cited: 44
Immunogenicity of clinically relevant SARS-CoV-2 vaccines in nonhuman primates and humans. Science advances. 2021 Information Resource GET IT
Times cited: 86
Antiretroviral drug activity and potential for pre-exposure prophylaxis against COVID-19 and HIV infection. Journal of biomolecular structure & dynamics. 2021 Academic Article GET IT
Times cited: 10
Anticipated reduction in COVID-19 mortality due to population-wide BCG vaccination: evidence from Germany. Human vaccines & immunotherapeutics. 2021 Article GET IT
Times cited: 16
Factors associated with attitudes towards HIV cure research among transgender women and travestis: a cross-sectional survey in São Paulo, Brazil. BMJ open. 2020 Academic Article GET IT
Times cited: 12
Telomere length and human hippocampal neurogenesis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2020 Academic Article GET IT
Times cited: 28
Human Endogenous Retrovirus Expression Is Associated with Head and Neck Cancer and Differential Survival. Viruses. 2020 Academic Article GET IT
Times cited: 29
Montelukast drug activity and potential against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Journal of medical virology. 2020 Article GET IT
Times cited: 18
Epidemiological evidence for association between higher influenza vaccine uptake in the elderly and lower COVID-19 deaths in Italy. Journal of medical virology. 2020 Article GET IT
Times cited: 137
Comments on "coinfection of SARS-CoV-2 and HIV in a patient in Wuhan city, China". Journal of medical virology. 2020 Article GET IT
Times cited: 6
The behavioral, cellular and immune mediators of HIV-1 acquisition: New insights from population genetics. Scientific reports. 2020 Academic Article GET IT
Times cited: 9
Transcriptomic analysis of human endogenous retroviruses in systemic lupus erythematosus. Proceedings of the National Academy of Sciences of the United States of America. 2019 Article GET IT
Times cited: 13
Telescope: Characterization of the retrotranscriptome by accurate estimation of transposable element expression. PLoS computational biology. 2019 Academic Article GET IT
Times cited: 132
The CD4^-CD8^- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8⁺ MAIT cell pool. Proceedings of the National Academy of Sciences of the United States of America. 2018 Academic Article GET IT
Times cited: 150
Dicer-2 Regulates Resistance and Maintains Homeostasis against Zika Virus Infection in Drosophila. Journal of immunology (Baltimore, Md. : 1950). 2018 Academic Article GET IT
Times cited: 39
HLA-C downregulation by HIV-1 adapts to host HLA genotype. PLoS pathogens. 2018 Academic Article GET IT
Times cited: 24
TGF-β Sustains Tumor Progression through Biochemical and Mechanical Signal Transduction. Cancers. 2018 Information Resource GET IT
Times cited: 51

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Research

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Funding awarded

REACH: Research Enterprise to Advance a Cure for HIV awarded by National Institute of Allergy & Infectious Diseases Co-Principal Investigator 2021 - 2027
HOPE - HIV Obstruction by Programmed Epigenetics awarded by Michael J. Fox Foundation for Parkinson''s Research Co-Principal Investigator 2021 - 2026

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Background

education and training

D.Phil., Oxford University (United Kingdom) 1992
M.A., Oxford University (United Kingdom) 1991
M.B.,B.S., Imperial College London Faculty of Medicine (United Kingdom) 1984
B.Sc., University College London (United Kingdom) 1981

Contact

full name

Douglas Nixon

primary email

dnixon@med.cornell.edu

VIVO Weill Cornell Medical College

Douglas Nixon Adjunct Professor of Immunology in Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email