selected publications
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Effect of Osimertinib and Bevacizumab on Progression-Free Survival for Patients With Metastatic EGFR-Mutant Lung Cancers: A Phase 1/2 Single-Group Open-Label Trial.
JAMA oncology.
2020
Academic Article
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Times cited: 106 -
COVID-19 in patients with lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology.
2020
Academic Article
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Times cited: 196 -
Pan-Cancer Efficacy of Vemurafenib in BRAF V600-Mutant Non-Melanoma Cancers.
Cancer discovery.
2020
Academic Article
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Times cited: 95 -
EGFR mutation subtypes and response to immune checkpoint blockade treatment in non-small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology.
2019
Academic Article
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Times cited: 262 -
Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2019
Academic Article
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Times cited: 247 -
A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers.
Journal of the National Cancer Institute.
2019
Academic Article
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Times cited: 98 -
Severe immune-related adverse events are common with sequential PD-(L)1 blockade and osimertinib.
Annals of oncology : official journal of the European Society for Medical Oncology.
2019
Academic Article
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Times cited: 287 -
Exceptional responders with invasive mucinous adenocarcinomas: a phase 2 trial of bortezomib in patients with KRAS G12D-mutant lung cancers.
Cold Spring Harbor molecular case studies.
2019
Academic Article
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Times cited: 23 -
Impact of Baseline Steroids on Efficacy of Programmed Cell Death-1 and Programmed Death-Ligand 1 Blockade in Patients With Non-Small-Cell Lung Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
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Times cited: 379 -
Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with EGFR-Mutant Lung Cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 254 -
Frequency of Brain Metastases and Multikinase Inhibitor Outcomes in Patients With RET-Rearranged Lung Cancers.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2018
Academic Article
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Times cited: 150 -
Brigatinib in Patients With Alectinib-Refractory ALK-Positive NSCLC.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2018
Academic Article
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Times cited: 68 -
YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.
Proceedings of the National Academy of Sciences of the United States of America.
2018
Academic Article
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Times cited: 42 - Improving therapy for patients with epidermal growth factor receptor-mutant lung cancer. Cancer. 2018 Editorial Article GET IT
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Response to ERBB3-Directed Targeted Therapy in NRG1-Rearranged Cancers.
Cancer discovery.
2018
Academic Article
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Times cited: 151 -
Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 204 -
Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2018
Academic Article
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Times cited: 1060 -
Effects of Co-occurring Genomic Alterations on Outcomes in Patients with KRAS-Mutant Non-Small Cell Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2017
Academic Article
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Times cited: 320 -
Twice weekly pulse and daily continuous-dose erlotinib as initial treatment for patients with epidermal growth factor receptor-mutant lung cancers and brain metastases.
Cancer.
2017
Academic Article
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Times cited: 28 -
Systemic Therapy for Stage IV Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2017
Academic Article
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Times cited: 324 -
Expression of PD-L1 and other immunotherapeutic targets in thymic epithelial tumors.
PloS one.
2017
Academic Article
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Times cited: 55 -
An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer.
Nature medicine.
2017
Academic Article
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Times cited: 125 -
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.
Nature medicine.
2017
Academic Article
GET IT
Times cited: 2338 -
Patterns of initial and intracranial failure in metastatic EGFR-mutant non-small cell lung cancer treated with erlotinib.
Lung cancer (Amsterdam, Netherlands).
2017
Academic Article
GET IT
Times cited: 43 -
Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 490 -
Investigation of patterns of nodal metastases in BRAF mutant lung cancer.
Lung cancer (Amsterdam, Netherlands).
2017
Academic Article
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Times cited: 10 -
Diagnosis and Treatment of Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer.
Hematology/oncology clinics of North America.
2017
Information Resource
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Times cited: 37 -
Phase 1 study of twice weekly pulse dose and daily low-dose erlotinib as initial treatment for patients with EGFR-mutant lung cancers.
Annals of oncology : official journal of the European Society for Medical Oncology.
2017
Academic Article
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Times cited: 39 -
Targeting ALK: Precision Medicine Takes on Drug Resistance.
Cancer discovery.
2017
Information Resource
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Times cited: 416 -
Renal cyst formation in patients treated with crizotinib for non-small cell lung cancer-Incidence, radiological features and clinical characteristics.
Lung cancer (Amsterdam, Netherlands).
2017
Academic Article
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Times cited: 17 -
Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
Academic Article
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Times cited: 65 -
Radiogenomic evaluation of lung cancer - Are there imaging characteristics associated with lung adenocarcinomas harboring BRAF mutations?.
Clinical imaging.
2016
Academic Article
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Times cited: 15 -
Cabozantinib in patients with advanced RET-rearranged non-small-cell lung cancer: an open-label, single-centre, phase 2, single-arm trial.
The Lancet. Oncology.
2016
Academic Article
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Times cited: 372 -
Clinician Perspectives on Current Issues in Lung Cancer Drug Development.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2016
Information Resource
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Times cited: 7 -
Dabrafenib in patients with BRAF(V600E)-positive advanced non-small-cell lung cancer: a single-arm, multicentre, open-label, phase 2 trial.
The Lancet. Oncology.
2016
Academic Article
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Times cited: 382 -
Clinical outcomes with pemetrexed-based systemic therapies in RET-rearranged lung cancers.
Annals of oncology : official journal of the European Society for Medical Oncology.
2016
Academic Article
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Times cited: 97 -
Activity and safety of ceritinib in patients with ALK-rearranged non-small-cell lung cancer (ASCEND-1): updated results from the multicentre, open-label, phase 1 trial.
The Lancet. Oncology.
2016
Academic Article
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Times cited: 422 -
Large Cell Neuroendocrine Carcinoma of the Lung: Clinico-Pathologic Features, Treatment, and Outcomes.
Clinical lung cancer.
2016
Academic Article
GET IT
Times cited: 118 -
Alectinib in ALK-positive, crizotinib-resistant, non-small-cell lung cancer: a single-group, multicentre, phase 2 trial.
The Lancet. Oncology.
2015
Academic Article
GET IT
Times cited: 587 -
Detection of T790M, the Acquired Resistance EGFR Mutation, by Tumor Biopsy versus Noninvasive Blood-Based Analyses.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2015
Academic Article
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Times cited: 319 -
Epidermal growth factor receptor exon 20 insertions in advanced lung adenocarcinomas: Clinical outcomes and response to erlotinib.
Cancer.
2015
Academic Article
GET IT
Times cited: 184 -
EGFR: The Paradigm of an Oncogene-Driven Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2015
Academic Article
GET IT
Times cited: 74 -
Phase I/II Study of HSP90 Inhibitor AUY922 and Erlotinib for EGFR-Mutant Lung Cancer With Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2015
Academic Article
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Times cited: 90 -
Differences in the survival of patients with recurrent versus de novo metastatic KRAS-mutant and EGFR-mutant lung adenocarcinomas.
Cancer.
2015
Academic Article
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Times cited: 14 -
Prognostic impact of KRAS mutation subtypes in 677 patients with metastatic lung adenocarcinomas.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2015
Academic Article
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Times cited: 112 -
Massively parallel sequencing identifies recurrent mutations in TP53 in thymic carcinoma associated with poor prognosis.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2015
Academic Article
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Times cited: 33 -
Clinical Experience With Crizotinib in Patients With Advanced ALK-Rearranged Non-Small-Cell Lung Cancer and Brain Metastases.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2015
Academic Article
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Times cited: 558 -
Beyond "second-line" in non-small cell lung cancer: therapy and supportive care.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.
2015
Information Resource
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Times cited: 2 -
Clinical characteristics and outcomes for patients with thymic carcinoma: evaluation of Masaoka staging.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2014
Academic Article
GET IT
Times cited: 55 -
Non-small cell lung cancer, version 1.2015.
Journal of the National Comprehensive Cancer Network : JNCCN.
2014
Academic Article
GET IT
Times cited: 129 -
Clinical characteristics and course of 63 patients with BRAF mutant lung cancers.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2014
Academic Article
GET IT
Times cited: 106 -
Therapeutic strategies utilized in the setting of acquired resistance to EGFR tyrosine kinase inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2014
Information Resource
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Times cited: 76 -
Crizotinib in ROS1-rearranged non-small-cell lung cancer.
The New England journal of medicine.
2014
Academic Article
GET IT
Times cited: 1650 -
Are there imaging characteristics associated with lung adenocarcinomas harboring ALK rearrangements?.
Lung cancer (Amsterdam, Netherlands).
2014
Academic Article
GET IT
Times cited: 57 -
Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 study.
The Lancet. Oncology.
2014
Academic Article
GET IT
Times cited: 532 -
Trial of a 5-day dosing regimen of temozolomide in patients with relapsed small cell lung cancers with assessment of methylguanine-DNA methyltransferase.
Lung cancer (Amsterdam, Netherlands).
2014
Academic Article
GET IT
Times cited: 50 -
Associations between mutations and histologic patterns of mucin in lung adenocarcinoma: invasive mucinous pattern and extracellular mucin are associated with KRAS mutation.
The American journal of surgical pathology.
2014
Academic Article
GET IT
Times cited: 138 -
Dual inhibition of EGFR with afatinib and cetuximab in kinase inhibitor-resistant EGFR-mutant lung cancer with and without T790M mutations.
Cancer discovery.
2014
Academic Article
GET IT
Times cited: 341 -
Small-cell lung cancers in patients who never smoked cigarettes.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2014
Academic Article
GET IT
Times cited: 110 -
Prognostic significance of adenocarcinoma in situ, minimally invasive adenocarcinoma, and nonmucinous lepidic predominant invasive adenocarcinoma of the lung in patients with stage I disease.
The American journal of surgical pathology.
2014
Academic Article
GET IT
Times cited: 205 -
Ceritinib in ALK-rearranged non-small-cell lung cancer.
The New England journal of medicine.
2014
Academic Article
GET IT
Times cited: 1124 -
Erlotinib versus radiation therapy for brain metastases in patients with EGFR-mutant lung adenocarcinoma.
International journal of radiation oncology, biology, physics.
2014
Academic Article
GET IT
Times cited: 85 -
Failure patterns relative to radiation treatment fields for stage II-IV thymoma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2014
Academic Article
GET IT
Times cited: 24 -
Clinical benefit of continuing ALK inhibition with crizotinib beyond initial disease progression in patients with advanced ALK-positive NSCLC.
Annals of oncology : official journal of the European Society for Medical Oncology.
2014
Academic Article
GET IT
Times cited: 193 -
Poor response to erlotinib in patients with tumors containing baseline EGFR T790M mutations found by routine clinical molecular testing.
Annals of oncology : official journal of the European Society for Medical Oncology.
2014
Academic Article
GET IT
Times cited: 176 -
Cixutumumab for patients with recurrent or refractory advanced thymic epithelial tumours: a multicentre, open-label, phase 2 trial.
The Lancet. Oncology.
2014
Academic Article
GET IT
Times cited: 109 -
Structural, biochemical, and clinical characterization of epidermal growth factor receptor (EGFR) exon 20 insertion mutations in lung cancer.
Science translational medicine.
2013
Academic Article
GET IT
Times cited: 465 -
Phase II trial of neoadjuvant bevacizumab plus chemotherapy and adjuvant bevacizumab in patients with resectable nonsquamous non-small-cell lung cancers.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2013
Academic Article
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Times cited: 114 -
The impact of cigarette smoking on the frequency of and qualitative differences in KRAS mutations in Korean patients with lung adenocarcinoma.
Yonsei medical journal.
2013
Academic Article
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Times cited: 19 -
Risk of hemoptysis in patients with resected squamous cell and other high-risk lung cancers treated with adjuvant bevacizumab.
Cancer chemotherapy and pharmacology.
2013
Academic Article
GET IT
Times cited: 14 -
Crizotinib versus chemotherapy in advanced ALK-positive lung cancer.
The New England journal of medicine.
2013
Academic Article
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Times cited: 2551 -
ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2013
Academic Article
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Times cited: 531 -
KRAS mutations are associated with solid growth pattern and tumor-infiltrating leukocytes in lung adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2013
Academic Article
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Times cited: 99 -
Characteristics of lung cancers harboring NRAS mutations.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2013
Academic Article
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Times cited: 126 -
Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2013
Academic Article
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Times cited: 2085 -
Local therapy with continued EGFR tyrosine kinase inhibitor therapy as a treatment strategy in EGFR-mutant advanced lung cancers that have developed acquired resistance to EGFR tyrosine kinase inhibitors.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2013
Academic Article
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Times cited: 290 -
New pathologic classification of lung cancer: relevance for clinical practice and clinical trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2013
Information Resource
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Times cited: 328 -
Second-generation epidermal growth factor receptor tyrosine kinase inhibitors in lung cancers.
Journal of the National Comprehensive Cancer Network : JNCCN.
2013
Academic Article
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Times cited: 68 -
Lungs don't forget: Comparison of the KRAS and EGFR mutation profile and survival of collegiate smokers and never smokers with advanced lung cancers.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2013
Academic Article
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Times cited: 26 -
Distinct clinical course of EGFR-mutant resected lung cancers: results of testing of 1118 surgical specimens and effects of adjuvant gefitinib and erlotinib.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2012
Academic Article
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Times cited: 128 -
Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: higher susceptibility of women to smoking-related KRAS-mutant cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2012
Academic Article
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Times cited: 516 -
HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation.
Cancer discovery.
2012
Academic Article
GET IT
Times cited: 613 -
Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study.
The Lancet. Oncology.
2012
Academic Article
GET IT
Times cited: 1123 -
Pemetrexed-based chemotherapy in patients with advanced, ALK-positive non-small cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology.
2012
Academic Article
GET IT
Times cited: 123 -
Association of KRAS and EGFR mutations with survival in patients with advanced lung adenocarcinomas.
Cancer.
2012
Academic Article
GET IT
Times cited: 126 -
Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
GET IT
Times cited: 395 -
Driver mutations determine survival in smokers and never-smokers with stage IIIB/IV lung adenocarcinomas.
Cancer.
2012
Academic Article
GET IT
Times cited: 49 -
Phase II trial of temozolomide in patients with relapsed sensitive or refractory small cell lung cancer, with assessment of methylguanine-DNA methyltransferase as a potential biomarker.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2012
Academic Article
GET IT
Times cited: 111 -
Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling.
Molecular cancer therapeutics.
2011
Academic Article
GET IT
Times cited: 182 -
Management and outcomes of relapse after treatment for thymoma and thymic carcinoma.
The Annals of thoracic surgery.
2011
Academic Article
GET IT
Times cited: 34 - Poly adenosine diphosphate-ribose polymerase inhibitors and heat shock protein 90 inhibitors. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2011 Academic Article GET IT
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Subtyping of non-small cell lung carcinoma: a comparison of small biopsy and cytology specimens.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2011
Academic Article
GET IT
Times cited: 96 -
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis.
The Lancet. Oncology.
2011
Academic Article
GET IT
Times cited: 819 -
Disease flare after tyrosine kinase inhibitor discontinuation in patients with EGFR-mutant lung cancer and acquired resistance to erlotinib or gefitinib: implications for clinical trial design.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2011
Academic Article
GET IT
Times cited: 377 -
Maintained sensitivity to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer recurring after adjuvant erlotinib or gefitinib.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2011
Academic Article
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Times cited: 58 -
A phase II trial of Salirasib in patients with lung adenocarcinomas with KRAS mutations.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2011
Academic Article
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Times cited: 95 -
Nomogram to predict the presence of EGFR activating mutation in lung adenocarcinoma.
The European respiratory journal.
2011
Academic Article
GET IT
Times cited: 61 -
Variability of lung tumor measurements on repeat computed tomography scans taken within 15 minutes.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2011
Academic Article
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Times cited: 135 -
Chemotherapy definitions and policies for thymic malignancies.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2011
Academic Article
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Times cited: 56 -
Phase II trial of dasatinib for patients with acquired resistance to treatment with the epidermal growth factor receptor tyrosine kinase inhibitors erlotinib or gefitinib.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2011
Academic Article
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Times cited: 65 -
Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2011
Academic Article
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Times cited: 604 -
Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2011
Academic Article
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Times cited: 249 -
A phase 2 study of weekly albumin-bound paclitaxel (Abraxane®) given as a two-hour infusion.
Cancer chemotherapy and pharmacology.
2011
Academic Article
GET IT
Times cited: 27 -
Suitability of thoracic cytology for new therapeutic paradigms in non-small cell lung carcinoma: high accuracy of tumor subtyping and feasibility of EGFR and KRAS molecular testing.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2011
Academic Article
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Times cited: 203 -
Impact of proposed IASLC/ATS/ERS classification of lung adenocarcinoma: prognostic subgroups and implications for further revision of staging based on analysis of 514 stage I cases.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2011
Academic Article
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Times cited: 667 -
Phase I/II trial of cetuximab and erlotinib in patients with lung adenocarcinoma and acquired resistance to erlotinib.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2011
Academic Article
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Times cited: 111 -
Rebiopsy of lung cancer patients with acquired resistance to EGFR inhibitors and enhanced detection of the T790M mutation using a locked nucleic acid-based assay.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2011
Academic Article
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Times cited: 532 -
Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2011
Academic Article
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Times cited: 118 -
Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: distinct natural history of patients with tumors harboring the T790M mutation.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2010
Academic Article
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Times cited: 562 -
Phase II trial of gefitinib and everolimus in advanced non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2010
Academic Article
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Times cited: 83 -
Insulin-like growth factor-1 receptor expression in thymic malignancies.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2010
Academic Article
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Times cited: 39 -
Erlotinib at a dose of 25 mg daily for non-small cell lung cancers with EGFR mutations.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2010
Academic Article
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Times cited: 74 -
Non-small cell lung cancer.
Journal of the National Comprehensive Cancer Network : JNCCN.
2010
Information Resource
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Times cited: 484 -
Pack-years of cigarette smoking as a prognostic factor in patients with stage IIIB/IV nonsmall cell lung cancer.
Cancer.
2010
Academic Article
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Times cited: 109 -
Analysis of genetic variants in never-smokers with lung cancer facilitated by an Internet-based blood collection protocol: a preliminary report.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2010
Academic Article
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Times cited: 78 -
Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2009
Academic Article
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Times cited: 733 -
Comprehensive genomic analysis reveals clinically relevant molecular distinctions between thymic carcinomas and thymomas.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2009
Academic Article
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Times cited: 174 -
Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2009
Academic Article
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Times cited: 363 -
Comparison of patterns of relapse in thymic carcinoma and thymoma.
The Journal of thoracic and cardiovascular surgery.
2009
Academic Article
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Times cited: 111 -
Evaluating variability in tumor measurements from same-day repeat CT scans of patients with non-small cell lung cancer.
Radiology.
2009
Academic Article
GET IT
Times cited: 278 -
Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2008
Academic Article
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Times cited: 42 -
Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2008
Academic Article
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Times cited: 168 -
Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2008
Academic Article
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Times cited: 502 -
Lung adenocarcinoma: modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and micropapillary adenocarcinoma subtypes, EGFR mutations and gene expression analysis.
The American journal of surgical pathology.
2008
Academic Article
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Times cited: 324 -
EGFR mutations in lung adenocarcinomas: clinical testing experience and relationship to EGFR gene copy number and immunohistochemical expression.
The Journal of molecular diagnostics : JMD.
2008
Academic Article
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Times cited: 182 -
Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2008
Academic Article
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Times cited: 275 -
Multimodality therapy for locally advanced thymomas: state of the art or investigational therapy?.
The Annals of thoracic surgery.
2008
Editorial Article
GET IT
Times cited: 17 -
Phase I/II trial of weekly intravenous 130-nm albumin-bound paclitaxel as initial chemotherapy in patients with stage IV non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2008
Academic Article
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Times cited: 101 -
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib.
Proceedings of the National Academy of Sciences of the United States of America.
2007
Academic Article
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Times cited: 1528 -
Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2007
Academic Article
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Times cited: 254 -
Novel agents in the treatment of lung cancer: Fourth Cambridge Conference.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2007
Conference Paper
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Times cited: 7 -
Phase 1 trial of everolimus and gefitinib in patients with advanced nonsmall-cell lung cancer.
Cancer.
2007
Academic Article
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Times cited: 92 -
Update on epidermal growth factor receptor mutations in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2006
Information Resource
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Times cited: 311 -
A phase 2 study of TZT-1027, administered weekly to patients with advanced non-small cell lung cancer following treatment with platinum-based chemotherapy.
Lung cancer (Amsterdam, Netherlands).
2006
Academic Article
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Times cited: 57 -
Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2006
Academic Article
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Times cited: 673 -
Molecular on/off switch.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2006
Academic Article
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Times cited: 10 -
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alpha2-macroglobulin modulates the immunoregulatory function of the lipocalin placental protein 14.
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Placental protein 14 functions as a direct T-cell inhibitor.
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Isolation and characterization of a TATA-less promoter for the human beta 3 integrin gene.
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