selected publications
- MAP kinase kinase 1 (MEK1) within extracellular vesicles inhibits tumour growth by promoting anti-tumour immunity. Journal of extracellular vesicles. 2024 Academic Article GET IT
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Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.
Nature medicine.
2024
Academic Article
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Times cited: 4 -
Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA).
Nature communications.
2024
Academic Article
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Times cited: 14 - Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction. Nature communications. 2024 Academic Article GET IT
- Molecular and physiologic changes in the SpaceX Inspiration4 civilian crew. Nature. 2024 Academic Article GET IT
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Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight.
Nature communications.
2024
Academic Article
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Times cited: 10 -
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight.
Nature communications.
2024
Academic Article
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Times cited: 16 - Spatiotemporal expression and control of haemoglobin in space. Nature communications. 2024 Academic Article GET IT
- The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. Nature. 2024 Academic Article GET IT
- Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load. Cell reports. 2024 Academic Article GET IT
- Tumour-derived Extracellular Vesicle and Particle Reprogramming of Interstitial Macrophages in the Lung Pre-Metastatic Niche Enhances Vascular Permeability and Metastatic Potential. 2024 GET IT
- Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight. Precision clinical medicine. 2024 Academic Article GET IT
- Protocol for cross-platform characterization of human and murine extracellular vesicles and particles. STAR protocols. 2023 Academic Article GET IT
- Advancement in Cellular Topographic and Nanoparticle Capture Imaging by High Resolution Microscopy Incorporating a Freeze-Drying and Gaseous Nitrogen-based Approach. 2023 GET IT
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Extracellular vesicles and particles as mediators of long-range communication in cancer: connecting biological function to clinical applications.
Extracellular vesicles and circulating nucleic acids.
2023
Academic Article
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Times cited: 11 -
Weaving the nest: extracellular matrix roles in pre-metastatic niche formation.
Frontiers in oncology.
2023
Review
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Times cited: 9 -
Tumour extracellular vesicles and particles induce liver metabolic dysfunction.
Nature.
2023
Academic Article
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Times cited: 76 - The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche. Journal of extracellular vesicles. 2023 Academic Article GET IT
- Genomic mapping of metastatic organotropism in lung adenocarcinoma. Cancer cell. 2023 Academic Article GET IT
- Immune determinants of the pre-metastatic niche. Cancer cell. 2023 Review GET IT
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Mast cells impair melanoma cell homing and metastasis by inhibiting HMGA1 secretion.
Immunology.
2022
Academic Article
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Times cited: 3 - Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection. Gut microbes. 2022 Academic Article GET IT
- Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism. Nature cancer. 2021 Academic Article GET IT
- Extracellular vesicle- and particle-mediated communication shapes innate and adaptive immune responses. The Journal of experimental medicine. 2021 Information Resource GET IT
- The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings. Molecular oncology. 2021 Academic Article GET IT
- Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids. STAR protocols. 2020 Academic Article GET IT
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Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers.
iScience.
2020
Academic Article
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Times cited: 37 -
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
Cell.
2020
Academic Article
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Times cited: 761 -
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis.
Nature cell biology.
2019
Academic Article
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Times cited: 276 -
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.
Nature cell biology.
2018
Academic Article
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Times cited: 1171 -
A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma.
The Journal of clinical investigation.
2017
Academic Article
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Times cited: 31 -
Pre-metastatic niches: organ-specific homes for metastases.
Nature reviews. Cancer.
2017
Information Resource
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Times cited: 624 -
Tumour exosome integrins determine organotropic metastasis.
Nature.
2015
Academic Article
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Times cited: 3721 -
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nature cell biology.
2015
Academic Article
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Times cited: 2055 -
Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation.
Nature communications.
2015
Academic Article
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Times cited: 87 -
Efficacy and safety of CDX-301, recombinant human Flt3L, at expanding dendritic cells and hematopoietic stem cells in healthy human volunteers.
Bone marrow transplantation.
2015
Academic Article
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Times cited: 82 -
IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.
Nature immunology.
2015
Academic Article
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Times cited: 88 -
Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.
Science translational medicine.
2014
Academic Article
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Times cited: 29 -
Double-stranded DNA in exosomes: a novel biomarker in cancer detection.
Cell research.
2014
Article
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Times cited: 1309 -
The perivascular niche regulates breast tumour dormancy.
Nature cell biology.
2013
Academic Article
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Times cited: 875 -
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Nature medicine.
2012
Academic Article
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Times cited: 2990 -
A TeNaCious foundation for the metastatic niche.
Cancer cell.
2011
Article
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Times cited: 5 -
Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors.
Blood.
2010
Academic Article
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Times cited: 20 -
ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes.
Blood.
2006
Academic Article
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Times cited: 38 -
ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection.
Immunological reviews.
2006
Review
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Times cited: 61 -
Somatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotype.
BMC genetics.
2001
Academic Article
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Times cited: 22