Prof. Ketterling’s research is focused on the development and translation of ultrasound technology to basic science, small-animal and clinical applications. He has over 25 years of research experience in ultrasound imaging and therapy topics primarily supported through National Institutes grant awards.

Prof. Ketterling has worked extensively with high-frequency ultrasound (> 20 MHz). He developed and patented a method of fabricating annular-array transducers and designed imaging platforms for ophthalmic human subject use and studies of in utero mouse embryonic central nervous system development. The work was extended to in vivo photoacoustic imaging of mouse embryos. The transducer technology was licensed for ophthalmic ultrasound imaging.

More recently, Dr, Ketterling has shifted into a new research area focused on high-speed plane-wave ultrasound imaging. The technology was applied to several applications including intracardiac flow patterns in mouse embryos and adult mice, blood flow in the front and back of the human eye, and activation of acoustic nanodrops for imaging microcirculation using methods such as super-resolution localization microscopy.