Prof. Ketterling’s research is focused on the development and translation of ultrasound technology to basic science, small-animal and clinical applications. Over 20 years of National Institutes of Health funded research experience in a variety of ultrasound imaging and therapy topics.

Prof. Ketterling has worked extensively with high-frequency ultrasound (> 20 MHz). He developed and patented a method of fabricating annular-array transducers and designed imaging platforms for ophthalmic human subject use and studies of in utero mouse embryonic central nervous system development. The work was extended to in vivo photoacoustic imaging of mouse embryos. The transducer technology was licensed for ophthalmic ultrasound imaging.

More recently, Dr, Ketterling has shifted into a new research area focused on high-speed plane-wave ultrasound imaging. The technology was applied to several applications including intracardiac flow patterns in mouse embryos and adult mice, blood flow in the front and back of the human eye, and activation of acoustic nanodrops for imaging microcirculation using methods such as super-resolution localization microscopy.