selected publications
- Multiomics Resolves Regulatory Mechanisms in a Diverse Cohort of Crohn's Disease. Journal of Crohn's & colitis. 2024 Editorial Article GET IT
- Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load. Cell reports. 2024 Academic Article GET IT
- Sounding the alarm in the lung with TL1A. The Journal of experimental medicine. 2024 Academic Article GET IT
- Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn. Nature communications. 2024 Academic Article GET IT
- The gut microbiome regulates the clinical efficacy of sulfasalazine therapy for IBD-associated spondyloarthritis. Cell reports. Medicine. 2024 Academic Article GET IT
- Baseline serum and stool microbiome biomarkers predict clinical efficacy and tissue molecular response after ritlecitinib induction therapy in ulcerative colitis. Journal of Crohn's & colitis. 2023 Academic Article GET IT
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Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15.
Nature communications.
2023
Academic Article
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Times cited: 7 - Higher Adalimumab Trough Levels Are Associated with Histologic Remission and Mucosal Healing in Inflammatory Bowel Disease. Journal of clinical medicine. 2023 Academic Article GET IT
- The Relationship Between the Endoscopic Healing Index, Fecal Calprotectin, and Magnetic Resonance Enterography in Crohn's Disease. Journal of clinical gastroenterology. 2023 Academic Article GET IT
- Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn. 2023 GET IT
- The Impact of Confounders on Symptom-Endoscopic Discordances in Crohn's Disease. Crohn's & colitis 360. 2023 Academic Article GET IT
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Acute high-fat diet impairs macrophage-supported intestinal damage resolution.
JCI insight.
2023
Academic Article
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Times cited: 6 -
Inflammatory Bowel Disease-Associated Gut Commensals Degrade Components of the Extracellular Matrix.
mBio.
2022
Academic Article
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Times cited: 10 - Serum Ustekinumab Concentrations Are Associated With Improved Outcomes With the Magnetic Resonance Index of Activity for Crohn's Disease. Inflammatory bowel diseases. 2022 Academic Article GET IT
- Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis. Cell reports. 2022 Academic Article GET IT
- Increased Primary Bile Acids with Ileocolonic Resection Impact Ileal Inflammation and Gut Microbiota in Inflammatory Bowel Disease. Journal of Crohn's & colitis. 2022 Academic Article GET IT
- Prevalence and factors associated with vitamin C deficiency in inflammatory bowel disease. World journal of gastroenterology. 2022 Academic Article GET IT
- A metagenomic DNA sequencing assay that is robust against environmental DNA contamination. Nature communications. 2022 Academic Article GET IT
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Phage display of environmental protein toxins and virulence factors reveals the prevalence, persistence, and genetics of antibody responses.
Immunity.
2022
Academic Article
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Times cited: 16 - Mucosal metabolites fuel the growth and virulence of E. coli linked to Crohn's disease. JCI insight. 2022 Academic Article GET IT
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Human gut bacteria produce ΤΗ17-modulating bile acid metabolites.
Nature.
2022
Academic Article
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Times cited: 270 - Eating for Two: Diet and the Microbiome in Ulcerative Colitis. Journal of Crohn's & colitis. 2022 Editorial Article GET IT
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A Quality Improvement Initiative Is Associated With Reduced Time to Administer Biologics and Small Molecules and Emergency Room Visits in Inflammatory Bowel Disease.
Journal of clinical gastroenterology.
2022
Academic Article
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Times cited: 4 - Utility of Therapeutic Drug Monitoring for Tumor Necrosis Factor Antagonists and Ustekinumab in Postoperative Crohn's Disease. Inflammatory bowel diseases. 2022 Academic Article GET IT
- Joint Disease Activity in Inflammatory Bowel Disease-associated Peripheral Spondyloarthritis Stratifies Therapeutic Response. Gastro hep advances. 2022 Academic Article GET IT
- Genetic manipulation of gut microbes enables single-gene interrogation in a complex microbiome. Cell. 2022 Academic Article GET IT
- Microbiota manipulation to increase macrophage IL-10 improves colitis and limits colitis-associated colorectal cancer. Gut microbes. 2022 Academic Article GET IT
- Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn's disease. Nature microbiology. 2021 Academic Article GET IT
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Transferable Immunoglobulin A-Coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation.
Gastroenterology.
2021
Academic Article
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Times cited: 71 - SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. Cell stem cell. 2021 Academic Article GET IT
- Antitumor Necrosis Factor-like Ligand 1A Therapy Targets Tissue Inflammation and Fibrosis Pathways and Reduces Gut Pathobionts in Ulcerative Colitis. Inflammatory bowel diseases. 2021 Academic Article GET IT
- No Durable Impact of COVID-19 on Intestinal Disease Activity in Subjects With IBD. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021 Article GET IT
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Thymic development of gut-microbiota-specific T cells.
Nature.
2021
Academic Article
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Times cited: 116 -
Decoding the matrix: multiomics reveals host-microbe biomarker for inflammatory bowel disease.
The Journal of clinical investigation.
2021
Comment
GET IT
Times cited: 1 - Dual Biologic or Small Molecule Therapy for Treatment of Inflammatory Bowel Disease: A Systematic Review and Meta-analysis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021 Information Resource GET IT
- Adherent-invasive E. coli metabolism of propanediol in Crohn's disease regulates phagocytes to drive intestinal inflammation. Cell host & microbe. 2021 Academic Article GET IT
- Utility of magnetic resonance imaging in Crohn's associated sacroiliitis: A cross-sectional study. International journal of rheumatic diseases. 2021 Academic Article GET IT
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A Diamond in the Rough: IgA-Seq Signatures Stratify New Onset IBD.
Cell host & microbe.
2021
Comment
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Times cited: 4 - Patient-Preferences Favoring Treatment Discontinuation Are Reduced With Vedolizumab and Ustekinumab Compared With TNF Antagonists in Inflammatory Bowel Disease. Crohn's & colitis 360. 2020 Academic Article GET IT
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Baseline Disease Activity and Steroid Therapy Stratify Risk of COVID-19 in Patients With Inflammatory Bowel Disease.
Gastroenterology.
2020
Academic Article
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Times cited: 89 -
Defining the phenotype, pathogenesis and treatment of Crohn's disease associated spondyloarthritis.
Journal of gastroenterology.
2020
Information Resource
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Times cited: 7 -
Author Correction: Bile acid metabolites control TH17 and Treg cell differentiation.
2020
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Times cited: 19 -
Evaluation of a novel ultraviolet C irradiation locker for microbial sterilization of hospital laboratory coats.
The Journal of hospital infection.
2020
Article
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Times cited: 1 -
Bile acid metabolites control TH17 and Treg cell differentiation.
Nature.
2019
Academic Article
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Times cited: 773 -
Innate lymphoid cells link gut microbes with mucosal T cell immunity.
Gut microbes.
2019
Review
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Times cited: 21 -
The balance of power: innate lymphoid cells in tissue inflammation and repair.
The Journal of clinical investigation.
2019
Review
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Times cited: 39 -
Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis.
Cell host & microbe.
2019
Academic Article
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Times cited: 351 -
Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis.
Immunity.
2018
Academic Article
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Times cited: 114 -
Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses.
Immunity.
2018
Academic Article
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Times cited: 146 -
Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring.
Nature.
2017
Academic Article
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Times cited: 479 -
Regulation of inflammation by microbiota interactions with the host.
Nature immunology.
2017
Information Resource
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Times cited: 463 -
Single Delivery of High-Diversity Fecal Microbiota Preparation by Colonoscopy Is Safe and Effective in Increasing Microbial Diversity in Active Ulcerative Colitis.
Inflammatory bowel diseases.
2017
Academic Article
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Times cited: 93 -
IgA-coated E. coli enriched in Crohn's disease spondyloarthritis promote TH17-dependent inflammation.
Science translational medicine.
2017
Academic Article
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Times cited: 232 -
Crohn's Disease: Evolution, Epigenetics, and the Emerging Role of Microbiome-Targeted Therapies.
Current gastroenterology reports.
2016
Information Resource
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Times cited: 11 -
Vedolizumab and Infliximab Combination Therapy in the Treatment of Crohn's Disease.
The American journal of gastroenterology.
2015
Article
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Times cited: 30 -
The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity.
Current opinion in rheumatology.
2015
Review
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Times cited: 63 -
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.
Nature biotechnology.
2015
Academic Article
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Times cited: 27 -
CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.
The Journal of experimental medicine.
2014
Academic Article
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Times cited: 308 -
Microbiota: host interactions in mucosal homeostasis and systemic autoimmunity.
Cold Spring Harbor symposia on quantitative biology.
2014
Review
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Times cited: 40 -
Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis.
eLife.
2013
Academic Article
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Times cited: 1314 -
Microbial manipulation as primary therapy for Crohn's disease.
World journal of gastroenterology.
2013
Academic Article
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Times cited: 4 -
Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX(3)CR1(hi) cells.
Nature.
2013
Academic Article
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Times cited: 377 -
Esophagitis dissecans superficialis.
2011
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Times cited: 19 -
Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients.
The Journal of experimental medicine.
2007
Academic Article
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Times cited: 104 -
Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation.
Blood.
2006
Academic Article
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Times cited: 47 -
Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes.
The Journal of experimental medicine.
2005
Academic Article
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Times cited: 116 -
Normal functional capacity in circulating myeloid and plasmacytoid dendritic cells in patients with chronic hepatitis C.
The Journal of infectious diseases.
2005
Academic Article
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Times cited: 111 -
A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation.
Blood.
2005
Academic Article
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Times cited: 361 -
Presence of functional dendritic cells in patients chronically infected with hepatitis C virus.
Blood.
2003
Academic Article
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Times cited: 132 -
Methanococcus jannaschii prolyl-cysteinyl-tRNA synthetase possesses overlapping amino acid binding sites.
Biochemistry.
2001
Academic Article
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Times cited: 23 -
One polypeptide with two aminoacyl-tRNA synthetase activities.
Science (New York, N.Y.).
2000
Academic Article
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Times cited: 65