selected publications
- Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model. Neuron. 2024 Academic Article GET IT
- Mice lacking Astn2 have ASD-like behaviors and altered cerebellar circuit properties. Proceedings of the National Academy of Sciences of the United States of America. 2024 Academic Article GET IT
- APOE3 - R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition. 2024 GET IT
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Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Cell.
2024
Academic Article
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Times cited: 3 - Mice lacking Astn2 have ASD-like behaviors and altered cerebellar circuit properties. 2024 GET IT
- Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model. 2024 GET IT
- Human iPSC 4R tauopathy model uncovers modifiers of tau propagation. 2023 GET IT
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Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Nature neuroscience.
2023
Academic Article
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Times cited: 32 -
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
Cell.
2022
Academic Article
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Times cited: 124 - The Purkinje-myocardial junction is the anatomical origin of ventricular arrhythmia in CPVT. JCI insight. 2022 Academic Article GET IT
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AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
Science translational medicine.
2021
Academic Article
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Times cited: 58 -
Parallel ascending spinal pathways for affective touch and pain.
Nature.
2020
Academic Article
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Times cited: 121 -
Growth of Saccharomyces cerevisiae and Preparation of DNA.
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 2 -
Small-Scale Preparations of Yeast DNA.
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 3 -
One-Step Bacterial Artificial Chromosome (BAC) Modification: Cloning of the A Homology Arm into Reporter-Shuttle Vector.
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 4 -
One-Step Bacterial Artificial Chromosome (BAC) Modification: Preparation of Plasmids.
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 4 -
One-Step Bacterial Artificial Chromosome (BAC) Modification: Preparation of the A Homology Arm (A-Box).
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 5 - One-Step Bacterial Artificial Chromosome (BAC) Modification: Transfer of the Reporter Vector into BAC/RecA Cells and Selection of Co-Integrates. Cold Spring Harbor protocols. 2020 Academic Article GET IT
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One-Step Bacterial Artificial Chromosome (BAC) Modification: Transformation of the BAC Host with the RecA Vector.
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 2 -
Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Cloning of the A and B Homology Arms into the Shuttle Vector.
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 4 -
Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Electroporation of Competent BAC Host Cells with the Recombinant Shuttle Vector.
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 3 -
Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Preparation and Verification of the Recombinant Shuttle Vector.
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 5 -
Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Preparation of Shuttle Vector DNA.
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 6 -
Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Preparation of the A Homology Arm (A-Box) and B Homology Arm (B-Box).
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 3 -
Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Verification of Co-Integrates and Selection of Resolved BAC Clones.
Cold Spring Harbor protocols.
2020
Academic Article
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Times cited: 4 -
Examination of Bacterial Artificial Chromosome (BAC) DNA Quality and Quantity by Pulsed-Field Gel Electrophoresis.
Cold Spring Harbor protocols.
2019
Article
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Times cited: 8 - Large-Scale Preparation and Linearization of Bacterial Artificial Chromosome (BAC) DNA. Cold Spring Harbor protocols. 2019 Academic Article GET IT
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Small-Scale Isolation of Bacterial Artificial Chromosome (BAC) DNA and Verification by Polymerase Chain Reaction (PCR).
Cold Spring Harbor protocols.
2019
Academic Article
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Times cited: 6 -
Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.
Neuron.
2019
Academic Article
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Times cited: 85 -
Bone protection by inhibition of microRNA-182.
Nature communications.
2018
Academic Article
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Times cited: 75 -
Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models.
Nature communications.
2018
Academic Article
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Times cited: 28 -
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.
PLoS genetics.
2014
Academic Article
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Times cited: 102 -
Signaling role of prokineticin 2 on the estrous cycle of female mice.
PloS one.
2014
Academic Article
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Times cited: 16 -
Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling.
Immunity.
2013
Academic Article
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Times cited: 235 -
Current mouse and cell models in prostate cancer research.
Endocrine-related cancer.
2013
Information Resource
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Times cited: 96 -
BAC transgenic mice and the GENSAT database of engineered mouse strains.
Cold Spring Harbor protocols.
2013
Academic Article
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Times cited: 43 -
Mouse transgenesis in a single locus with independent regulation for multiple fluorophores.
PloS one.
2012
Academic Article
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Times cited: 9 -
The functional organization of cutaneous low-threshold mechanosensory neurons.
Cell.
2011
Academic Article
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Times cited: 542 -
Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement.
Neuron.
2011
Academic Article
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Times cited: 509 -
Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes.
Nature.
2010
Academic Article
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Times cited: 927 -
Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis.
Nature protocols.
2010
Academic Article
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Times cited: 60 -
A translational profiling approach for the molecular characterization of CNS cell types.
Cell.
2008
Academic Article
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Times cited: 881 -
Application of a translational profiling approach for the comparative analysis of CNS cell types.
Cell.
2008
Academic Article
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Times cited: 709 -
Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs.
Nature neuroscience.
2008
Academic Article
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Times cited: 202 -
Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice.
Autism research : official journal of the International Society for Autism Research.
2008
Academic Article
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Times cited: 243 -
Defining the expression pattern of the LGI1 gene in BAC transgenic mice.
Mammalian genome : official journal of the International Mammalian Genome Society.
2007
Academic Article
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Times cited: 47 -
Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library.
Stem cells (Dayton, Ohio).
2006
Academic Article
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Times cited: 32 -
Modified bacterial artificial chromosomes for zebrafish transgenesis.
Methods (San Diego, Calif.).
2006
Academic Article
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Times cited: 38 -
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.
Neuron.
2005
Academic Article
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Times cited: 189 -
An overview on the generation of BAC transgenic mice for neuroscience research.
Current protocols in neuroscience.
2005
Information Resource
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Times cited: 44 -
Modification of bacterial artificial chromosomes (BACs) and preparation of intact BAC DNA for generation of transgenic mice.
Current protocols in neuroscience.
2005
Academic Article
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Times cited: 15 -
General method for the modification of different BAC types and the rapid generation of BAC transgenic mice.
Genesis (New York, N.Y. : 2000).
2004
Academic Article
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Times cited: 51 -
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes.
Nature.
2003
Academic Article
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Times cited: 1493 -
B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta.
The Journal of experimental medicine.
2001
Academic Article
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Times cited: 97 -
A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells.
Human immunology.
2000
Academic Article
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Times cited: 105 -
DEC-205 as a marker of dendritic cells with regulatory effects on CD8 T cell responses.
International immunology.
2000
Academic Article
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Times cited: 55 -
Counterselection against D mu is mediated through immunoglobulin (Ig)alpha-Igbeta.
The Journal of experimental medicine.
1996
Academic Article
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Times cited: 20 -
The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes.
Nature.
1996
Academic Article
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Times cited: 203 -
Regulation of an early developmental checkpoint in the B cell pathway by Ig beta.
Science (New York, N.Y.).
1996
Academic Article
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Times cited: 236 -
The 32-kilodalton envelope protein of vaccinia virus synthesized in Escherichia coli binds with specificity to cell surfaces.
Journal of virology.
1991
Academic Article
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Times cited: 17 -
Structural and functional properties of the 14-kDa envelope protein of vaccinia virus synthesized in Escherichia coli.
The Journal of biological chemistry.
1990
Academic Article
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Times cited: 32 -
Vaccinia virus induces cell fusion at acid pH and this activity is mediated by the N-terminus of the 14-kDa virus envelope protein.
Virology.
1990
Academic Article
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Times cited: 89 -
A single point mutation of Ala-25 to Asp in the 14,000-Mr envelope protein of vaccinia virus induces a size change that leads to the small plaque size phenotype of the virus.
Journal of virology.
1989
Academic Article
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Times cited: 22