Jeitner, Thomas

Publications

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selected publications

Cystine rather than cysteine is the preferred substrate for β-elimination by cystathionine γ-lyase: implications for dietary methionine restriction. GeroScience. 2023 Academic Article GET IT
Times cited: 16
Stabilization of guinea pig transglutaminase 2 solutions. Analytical biochemistry. 2022 Academic Article GET IT
Advances in PSMA theranostics. Translational oncology. 2022 Academic Article GET IT
Neutrophil-Derived Myeloperoxidase and Hypochlorous Acid Critically Contribute to 20-Hydroxyeicosatetraenoic Acid Increases that Drive Postischemic Angiogenesis. The Journal of pharmacology and experimental therapeutics. 2022 Academic Article GET IT
Times cited: 1
Synthesis and Evaluation of ¹¹C-Labeled Triazolones as Probes for Imaging Fatty Acid Synthase Expression by Positron Emission Tomography. Molecules (Basel, Switzerland). 2022 Academic Article GET IT
A Trifunctional Theranostic Ligand Targeting Fibroblast Activation Protein-α (FAPα). Molecular imaging and biology. 2021 Academic Article GET IT
Times cited: 1
Mechanism of Fully Reversible, pH-Sensitive Inhibition of Human Glutamine Synthetase by Tyrosine Nitration. Journal of chemical theory and computation. 2020 Academic Article GET IT
Times cited: 5
Cystamine and cysteamine as inhibitors of transglutaminase activity in vivo. Bioscience reports. 2018 Information Resource GET IT
Times cited: 34
The Enzymology of 2-Hydroxyglutarate, 2-Hydroxyglutaramate and 2-Hydroxysuccinamate and Their Relationship to Oncometabolites. Biology. 2017 Academic Article GET IT
Times cited: 13
Fluorination at the 4 position alters the substrate behavior of L-glutamine and L-glutamate: Implications for positron emission tomography of neoplasias. Journal of fluorine chemistry. 2016 Academic Article GET IT
Times cited: 5
Linking Inflammation and Parkinson Disease: Hypochlorous Acid Generates Parkinsonian Poisons. 2016 GET IT
Times cited: 5
Linking Inflammation and Parkinson Disease: Hypochlorous Acid Generates Parkinsonian Poisons. Toxicological sciences : an official journal of the Society of Toxicology. 2016 Academic Article GET IT
Times cited: 48
Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain. Biomolecules. 2016 Information Resource GET IT
Times cited: 136
Serotonin as a putative scavenger of hypohalous acid in the brain. Biochimica et biophysica acta. 2015 Academic Article GET IT
Times cited: 18
Inflaming the diseased brain: a role for tainted melanins. Biochimica et biophysica acta. 2015 Academic Article GET IT
Times cited: 7
Optimized ferrozine-based assay for dissolved iron. Analytical biochemistry. 2014 Academic Article GET IT
Times cited: 42
Inhibition of human glutamine synthetase by L-methionine-S,R-sulfoximine-relevance to the treatment of neurological diseases. Metabolic brain disease. 2013 Academic Article GET IT
Times cited: 27
Preparation of 2-nitro-5-thiobenzoate for the routine determination of reagent hypochlorous acid concentrations. Analytical biochemistry. 2013 Academic Article GET IT
Times cited: 4
γ-Glutamylamines and neurodegenerative diseases. Amino acids. 2012 Information Resource GET IT
Times cited: 17
Cholinesterase inhibitors: applying pharmacokinetics to clinical decision making. The American journal of geriatric pharmacotherapy. 2011 Academic Article GET IT
Times cited: 5
Donepezil dosing strategies: pharmacokinetic considerations. Journal of the American Medical Directors Association. 2011 Academic Article GET IT
Times cited: 9
Oxysterol derivatives of cholesterol in neurodegenerative disorders. Current medicinal chemistry. 2011 Review GET IT
Times cited: 47
Once-daily memantine: pharmacokinetic and clinical considerations. Journal of the American Geriatrics Society. 2010 Letter GET IT
Times cited: 19
Transglutaminase activation in neurodegenerative diseases. Future neurology. 2009 Academic Article GET IT
Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2009 Academic Article GET IT
Times cited: 32
Increased levels of gamma-glutamylamines in Huntington disease CSF. Journal of neurochemistry. 2008 Academic Article GET IT
Times cited: 50
Lovastatin enhances phenylbutyrate-induced MR-visible glycerophosphocholine but not apoptosis in DU145 prostate cells. Biochimica et biophysica acta. 2007 Academic Article GET IT
Times cited: 13
Treatment of YAC128 mice and their wild-type littermates with cystamine does not lead to its accumulation in plasma or brain: implications for the treatment of Huntington disease. Journal of neurochemistry. 2005 Academic Article GET IT
Times cited: 46
Mechanism for the inhibition of transglutaminase 2 by cystamine. Biochemical pharmacology. 2005 Academic Article GET IT
Times cited: 84
Inhibition of the alpha-ketoglutarate dehydrogenase complex by the myeloperoxidase products, hypochlorous acid and mono-N-chloramine. Journal of neurochemistry. 2005 Academic Article GET IT
Times cited: 46
L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes?. The Biochemical journal. 2003 Academic Article GET IT
Times cited: 20
Therapeutic effects of cystamine in a murine model of Huntington's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002 Academic Article GET IT
Times cited: 298
Oxidative stress increases internal calcium stores and reduces a key mitochondrial enzyme. Biochimica et biophysica acta. 2002 Academic Article GET IT
Times cited: 43
Transglutaminases in disease. Neurochemistry international. 2002 Review GET IT
Times cited: 142
N(epsilon)-(gamma-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntington's disease. Journal of neurochemistry. 2001 Academic Article GET IT
Times cited: 80
Mechanisms for the cytotoxicity of cysteamine. Toxicological sciences : an official journal of the Society of Toxicology. 2001 Academic Article GET IT
Times cited: 58
A sensitive fluorometric assay for tissue transglutaminase. Analytical biochemistry. 2001 Academic Article GET IT
Times cited: 27
Oleic acid increases cell surface expression and activity of CD11b on human neutrophils. Journal of immunology (Baltimore, Md. : 1950). 1998 Academic Article GET IT
Times cited: 45
Inhibition of drug-naive and -resistant leukemia cell proliferation by low molecular weight thiols. Biochemical pharmacology. 1998 Academic Article GET IT
Times cited: 19
Induction of magnetic resonance-visible lipid in a transformed human breast cell line by tetraphenylphosphonium chloride. International journal of cancer. 1997 Academic Article GET IT
Times cited: 23
The accumulation of H-1 MR-visible lipid in human glioma cells is independent of the cell cycle. International journal of oncology. 1997 Academic Article GET IT
Tetraphenylphosphonium chloride induced MR-visible lipid accumulation in a malignant human breast cell line. International journal of cancer. 1996 Academic Article GET IT
Times cited: 39
Cell cycle-dependent inhibition of the proliferation of human neural tumor cell lines by iron chelators. Biochemical pharmacology. 1996 Academic Article GET IT
Times cited: 52
Inhibition of the proliferation of human neural neoplastic cell lines by cysteamine. Cancer letters. 1996 Academic Article GET IT
Times cited: 13
Modulation of MR-visible mobile lipid levels by cell culture conditions and correlations with chemotactic response. International journal of cancer. 1996 Academic Article GET IT
Times cited: 39
Transcription factors as targets for oxidative signalling during lymphocyte activation. Biochimica et biophysica acta. 1995 Academic Article GET IT
Times cited: 53
Thiol-bearing compounds selectively inhibit protein kinase C-dependent oxidative events and proliferation in human T cells. Biochimica et biophysica acta. 1994 Academic Article GET IT
Times cited: 20
Identification of apoptotic and necrotic human leukemic cells by flow cytometry. Experimental cell research. 1994 Academic Article GET IT
Times cited: 57
Possible oncostatic action of cysteamine on the pituitary glands of oestrogen-primed hyperprolactinaemic rats. The Journal of endocrinology. 1990 Academic Article GET IT
Times cited: 11
Effect of cysteamine on the lysosomal enzymes of the hyperprolactinaemic rat pituitary. The Journal of endocrinology. 1990 Academic Article GET IT
Times cited: 5
The depletion of plasma prolactin by pantethine in oestrogen-primed hyperprolactinaemic rats. The Journal of endocrinology. 1990 Academic Article GET IT
Times cited: 4

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Research

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Co-investigator Network

Funding awarded

Clinical and Translational Science Center- Institutional CTSC Internal Funding UL1 awarded by CTSC Cost Share Co-Investigator 2022 - 2027
The Development of Radiolabeled Positional isomers of [11C]Pyruvate for Imaging Cancer Metabolism Co-Investigator 2020 - 2024

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Background

education and training

Ph.D., Sydney University Medical School (Australia) 1994
M.Sc., Flinders University of S.A. (Australia) 1987
B.Sc., Flinders University of S.A. (Australia) 1982

Contact

full name

Thomas Jeitner

primary email

tmj4001@med.cornell.edu

VIVO Weill Cornell Medical College

Thomas Jeitner Assistant Professor of Biochemistry Research in Radiology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email