selected publications
- 2-[18F]Fluoropropionic Acid PET Imaging of Doxorubicin-induced Cardiotoxicity. 2024 GET IT
- Micronuclear collapse from oxidative damage. Science (New York, N.Y.). 2024 Academic Article GET IT
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Cystine rather than cysteine is the preferred substrate for β-elimination by cystathionine γ-lyase: implications for dietary methionine restriction.
GeroScience.
2023
Academic Article
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Times cited: 16 - Stabilization of guinea pig transglutaminase 2 solutions. Analytical biochemistry. 2022 Academic Article GET IT
- Advances in PSMA theranostics. Translational oncology. 2022 Academic Article GET IT
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Neutrophil-Derived Myeloperoxidase and Hypochlorous Acid Critically Contribute to 20-Hydroxyeicosatetraenoic Acid Increases that Drive Postischemic Angiogenesis.
The Journal of pharmacology and experimental therapeutics.
2022
Academic Article
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Times cited: 2 - Synthesis and Evaluation of 11C-Labeled Triazolones as Probes for Imaging Fatty Acid Synthase Expression by Positron Emission Tomography. Molecules (Basel, Switzerland). 2022 Academic Article GET IT
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A Trifunctional Theranostic Ligand Targeting Fibroblast Activation Protein-α (FAPα).
Molecular imaging and biology.
2021
Academic Article
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Times cited: 1 -
Mechanism of Fully Reversible, pH-Sensitive Inhibition of Human Glutamine Synthetase by Tyrosine Nitration.
Journal of chemical theory and computation.
2020
Academic Article
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Times cited: 5 -
Cystamine and cysteamine as inhibitors of transglutaminase activity in vivo.
Bioscience reports.
2018
Review
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Times cited: 39 -
The Enzymology of 2-Hydroxyglutarate, 2-Hydroxyglutaramate and 2-Hydroxysuccinamate and Their Relationship to Oncometabolites.
Biology.
2017
Academic Article
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Times cited: 13 -
Fluorination at the 4 position alters the substrate behavior of L-glutamine and L-glutamate: Implications for positron emission tomography of neoplasias.
Journal of fluorine chemistry.
2016
Academic Article
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Times cited: 5 -
Linking Inflammation and Parkinson Disease: Hypochlorous Acid Generates Parkinsonian Poisons.
2016
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Times cited: 6 -
Linking Inflammation and Parkinson Disease: Hypochlorous Acid Generates Parkinsonian Poisons.
Toxicological sciences : an official journal of the Society of Toxicology.
2016
Academic Article
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Times cited: 52 -
Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain.
Biomolecules.
2016
Review
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Times cited: 145 -
Serotonin as a putative scavenger of hypohalous acid in the brain.
Biochimica et biophysica acta.
2015
Academic Article
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Times cited: 18 -
Critical Evaluation of the Changes in Glutamine Synthetase Activity in Models of Cerebral Stroke.
Neurochemical research.
2015
Review
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Times cited: 30 -
Inflaming the diseased brain: a role for tainted melanins.
Biochimica et biophysica acta.
2015
Academic Article
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Times cited: 7 -
Optimized ferrozine-based assay for dissolved iron.
Analytical biochemistry.
2014
Academic Article
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Times cited: 49 -
Inhibition of human glutamine synthetase by L-methionine-S,R-sulfoximine-relevance to the treatment of neurological diseases.
Metabolic brain disease.
2013
Academic Article
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Times cited: 28 -
Preparation of 2-nitro-5-thiobenzoate for the routine determination of reagent hypochlorous acid concentrations.
Analytical biochemistry.
2013
Academic Article
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Times cited: 4 -
γ-Glutamylamines and neurodegenerative diseases.
Amino acids.
2012
Review
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Times cited: 18 -
Cholinesterase inhibitors: applying pharmacokinetics to clinical decision making.
The American journal of geriatric pharmacotherapy.
2011
Academic Article
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Times cited: 5 -
Donepezil dosing strategies: pharmacokinetic considerations.
Journal of the American Medical Directors Association.
2011
Academic Article
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Times cited: 9 -
Oxysterol derivatives of cholesterol in neurodegenerative disorders.
Current medicinal chemistry.
2011
Review
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Times cited: 49 -
Once-daily memantine: pharmacokinetic and clinical considerations.
Journal of the American Geriatrics Society.
2010
Letter
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Times cited: 20 -
Transglutaminase activation in neurodegenerative diseases.
Future neurology.
2009
Academic Article
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Times cited: 36 -
Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009
Academic Article
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Times cited: 33 -
Transglutaminases and neurodegeneration.
Journal of neurochemistry.
2009
Review
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Times cited: 77 -
Increased levels of gamma-glutamylamines in Huntington disease CSF.
Journal of neurochemistry.
2008
Academic Article
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Times cited: 50 -
Lovastatin enhances phenylbutyrate-induced MR-visible glycerophosphocholine but not apoptosis in DU145 prostate cells.
Biochimica et biophysica acta.
2007
Academic Article
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Times cited: 13 -
Treatment of YAC128 mice and their wild-type littermates with cystamine does not lead to its accumulation in plasma or brain: implications for the treatment of Huntington disease.
Journal of neurochemistry.
2005
Academic Article
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Times cited: 53 -
Mechanism for the inhibition of transglutaminase 2 by cystamine.
Biochemical pharmacology.
2005
Academic Article
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Times cited: 93 -
Inhibition of the alpha-ketoglutarate dehydrogenase complex by the myeloperoxidase products, hypochlorous acid and mono-N-chloramine.
Journal of neurochemistry.
2005
Academic Article
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Times cited: 46 -
L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes?.
The Biochemical journal.
2003
Academic Article
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Times cited: 21 -
Therapeutic effects of cystamine in a murine model of Huntington's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2002
Academic Article
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Times cited: 299 -
Oxidative stress increases internal calcium stores and reduces a key mitochondrial enzyme.
Biochimica et biophysica acta.
2002
Academic Article
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Times cited: 43 -
Transglutaminases in disease.
Neurochemistry international.
2002
Review
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Times cited: 143 -
N(epsilon)-(gamma-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntington's disease.
Journal of neurochemistry.
2001
Academic Article
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Times cited: 80 -
Mechanisms for the cytotoxicity of cysteamine.
Toxicological sciences : an official journal of the Society of Toxicology.
2001
Academic Article
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Times cited: 60 -
A sensitive fluorometric assay for tissue transglutaminase.
Analytical biochemistry.
2001
Academic Article
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Times cited: 27 -
Oleic acid increases cell surface expression and activity of CD11b on human neutrophils.
Journal of immunology (Baltimore, Md. : 1950).
1998
Academic Article
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Times cited: 45 -
Inhibition of drug-naive and -resistant leukemia cell proliferation by low molecular weight thiols.
Biochemical pharmacology.
1998
Academic Article
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Times cited: 19 -
Induction of magnetic resonance-visible lipid in a transformed human breast cell line by tetraphenylphosphonium chloride.
International journal of cancer.
1997
Academic Article
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Times cited: 23 - The accumulation of H-1 MR-visible lipid in human glioma cells is independent of the cell cycle. International journal of oncology. 1997 Academic Article GET IT
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Tetraphenylphosphonium chloride induced MR-visible lipid accumulation in a malignant human breast cell line.
International journal of cancer.
1996
Academic Article
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Times cited: 39 -
Cell cycle-dependent inhibition of the proliferation of human neural tumor cell lines by iron chelators.
Biochemical pharmacology.
1996
Academic Article
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Times cited: 53 -
Inhibition of the proliferation of human neural neoplastic cell lines by cysteamine.
Cancer letters.
1996
Academic Article
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Times cited: 13 -
Modulation of MR-visible mobile lipid levels by cell culture conditions and correlations with chemotactic response.
International journal of cancer.
1996
Academic Article
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Times cited: 40 -
Transcription factors as targets for oxidative signalling during lymphocyte activation.
Biochimica et biophysica acta.
1995
Academic Article
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Times cited: 53 -
Thiol-bearing compounds selectively inhibit protein kinase C-dependent oxidative events and proliferation in human T cells.
Biochimica et biophysica acta.
1994
Academic Article
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Times cited: 20 -
Identification of apoptotic and necrotic human leukemic cells by flow cytometry.
Experimental cell research.
1994
Academic Article
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Times cited: 57 -
Possible oncostatic action of cysteamine on the pituitary glands of oestrogen-primed hyperprolactinaemic rats.
The Journal of endocrinology.
1990
Academic Article
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Times cited: 11 -
Effect of cysteamine on the lysosomal enzymes of the hyperprolactinaemic rat pituitary.
The Journal of endocrinology.
1990
Academic Article
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Times cited: 5 -
The depletion of plasma prolactin by pantethine in oestrogen-primed hyperprolactinaemic rats.
The Journal of endocrinology.
1990
Academic Article
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Times cited: 4