publication venue for
- Blocking lipid synthesis induces DNA damage in prostate cancer and increases cell death caused by PARP inhibition.. 17. 2024
- Integrin-dependent recruitment of Src to ROS-producing endosomes in osteoarthritic cartilage.. 16. 2023
- Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.. 15. 2022
- Protein tyrosine phosphatase 1B regulates miR-208b-argonaute 2 association and thyroid hormone responsiveness in cardiac hypertrophy.. 15. 2022
- Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP.. 14. 2021
- Dynamic variability in SHP-1 abundance determines natural killer cell responsiveness.. 14. 2021
- IKKβ-NF-κB signaling in adult chondrocytes promotes the onset of age-related osteoarthritis in mice.. 14. 2021
- Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function.. 14. 2021
- GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma.. 13. 2020
- Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.. 12. 2019
- Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition.. 12. 2019
- Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH.. 11. 2018
- Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2).. 11. 2018
- Thyroid hormone receptor and ERRα coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function.. 11. 2018
- The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer.. 11. 2018
- Learning-dependent chromatin remodeling highlights noncoding regulatory regions linked to autism.. 11. 2018
- C-reactive protein promotes bone destruction in human myeloma through the CD32-p38 MAPK-Twist axis.. 10. 2017
- Foxo1 and Foxp1 play opposing roles in regulating the differentiation and antitumor activity of TH9 cells programmed by IL-7.. 10. 2017
- The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK.. 10. 2017
- Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment.. 10. 2017
- An engineered S1P chaperone attenuates hypertension and ischemic injury.. 10. 2017
- Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus.. 9. 2016
- JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors.. 9. 2016
- Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.. 8. 2015
- Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer.. 8. 2015
- ERK reinforces actin polymerization to power persistent edge protrusion during motility.. 8. 2015
- PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.. 8. 2015
- EGF induces microRNAs that target suppressors of cell migration: miR-15b targets MTSS1 in breast cancer.. 8. 2015
- The E3 ubiquitin ligase Itch inhibits p38α signaling and skin inflammation through the ubiquitylation of Tab1.. 8. 2015
- Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer.. 8. 2015
- Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia.. 7. 2014
- RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis.. 7. 2014
- Diacylglycerol kinase α establishes T cell polarity by shaping diacylglycerol accumulation at the immunological synapse.. 7. 2014
- A unified nomenclature and amino acid numbering for human PTEN.. 7. 2014
- Multifaceted activities of type I interferon are revealed by a receptor antagonist.. 7. 2014
- Protein tyrosine phosphatase 1B is a regulator of the interleukin-10-induced transcriptional program in macrophages.. 7. 2014
- Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer.. 7. 2014
- KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability.. 7. 2014
- mTORC1 promotes denervation-induced muscle atrophy through a mechanism involving the activation of FoxO and E3 ubiquitin ligases.. 7. 2014
- The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling.. 6. 2013
- Using functional signature ontology (FUSION) to identify mechanisms of action for natural products.. 6. 2013
- Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets.. 6. 2013
- Phosphatidylcholine transfer protein interacts with thioesterase superfamily member 2 to attenuate insulin signaling.. 6. 2013
- Regulators of calcium homeostasis identified by inference of kinetic model parameters from live single cells perturbed by siRNA.. 6. 2013
- AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve.. 6. 2013
- Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.. 6. 2013
- PUMA and BIM are required for oncogene inactivation-induced apoptosis.. 6. 2013
- Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus.. 5. 2012
- Akt and ERK control the proliferative response of mammary epithelial cells to the growth factors IGF-1 and EGF through the cell cycle inhibitor p57Kip2.. 5. 2012
- Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.. 4. 2011
- Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling.. 4. 2011
- Akt and autophagy cooperate to promote survival of drug-resistant glioma.. 3. 2010
- Evolution of CASK into a Mg2+-sensitive kinase.. 3. 2010
- Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.. 3. 2010
- Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor.. 3. 2010
- EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy.. 2. 2009
- The VDAC2-BAK rheostat controls thymocyte survival.. 2. 2009
- Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.. 2. 2009
- The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.. 2. 2009
- Differential requirement of mTOR in postmitotic tissues and tumorigenesis.. 2. 2009
- Maintaining diplomatic relations between mammals and beneficial microbial communities.. 2. 2009
- Resistance to MEK inhibitors: should we co-target upstream? 2011
- Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment. 2022