Lavi, Ehud

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selected publications

Novel activating BRAF fusion identifies a recurrent alternative mechanism for ERK activation in pediatric Langerhans cell histiocytosis. Pediatric blood & cancer. 2017 Academic Article GET IT
Times cited: 15
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway. Acta neuropathologica. 2016 Academic Article GET IT
Times cited: 199
CD1a Reactivity in Non-neoplastic Adenohypophysis. The American journal of surgical pathology. 2016 Academic Article GET IT
VZV, temporal arteritis, and clinical practice: False positive immunohistochemical detection due to antibody cross-reactivity. Experimental and molecular pathology. 2015 Academic Article GET IT
Times cited: 30
Pituitary adenoma-neuronal choristoma is a pituitary adenoma with ganglionic differentiation. Experimental and molecular pathology. 2015 Academic Article GET IT
Times cited: 9
Direct Invasion of the Optic Nerves, Chiasm, and Tracts by Cryptococcus neoformans in an Immunocompetent Host. The Neurohospitalist. 2015 Academic Article GET IT
Times cited: 23
Toxicity evaluation of prolonged convection-enhanced delivery of small-molecule kinase inhibitors in naïve rat brainstem. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 2014 Academic Article GET IT
Times cited: 6
Amyloid β-Related Central Nervous System Angiitis Presenting With an Isolated Seizure. The Neurohospitalist. 2014 Academic Article GET IT
Times cited: 7
Glioblastoma-arteriovenous fistula complex: imaging characteristics and treatment considerations. 2013 GET IT
Times cited: 4
Multinodular and vacuolating neuronal tumors of the cerebrum: 10 cases of a distinctive seizure-associated lesion. Brain pathology (Zurich, Switzerland). 2013 Academic Article GET IT
Times cited: 115
Phase I/II study of oral erlotinib for treatment of relapsed/refractory glioblastoma multiforme and anaplastic astrocytoma. Journal of experimental therapeutics & oncology. 2012 Academic Article GET IT
Times cited: 18
Prostate-specific membrane antigen as a potential novel vascular target for treatment of glioblastoma multiforme. Archives of pathology & laboratory medicine. 2011 Academic Article GET IT
Times cited: 61
Effects of high-fat diet and regular aerobic exercise on global gene expression in skeletal muscle of C57BL/6 mice. Metabolism: clinical and experimental. 2011 Academic Article GET IT
Times cited: 21
High frequency of IDH-1 mutation links glioneuronal tumors with neuropil-like islands to diffuse astrocytomas. Acta neuropathologica. 2011 Article GET IT
Times cited: 17
Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses. Journal of immunology (Baltimore, Md. : 1950). 2009 Academic Article GET IT
Times cited: 197
Suppression of neuroinflammation and immunomodulation by the acetylcholinesterase inhibitor rivastigmine. Journal of neuroimmunology. 2008 Academic Article GET IT
Times cited: 97
Effect of DAB(389)IL-2 immunotoxin on the course of experimental autoimmune encephalomyelitis in Lewis rats. Journal of the neurological sciences. 2007 Academic Article GET IT
Times cited: 18
alpha-Defensin: link between inflammation and atherosclerosis. Atherosclerosis. 2006 Academic Article GET IT
Times cited: 25
Recombinant mouse hepatitis virus strain A59 from cloned, full-length cDNA replicates to high titers in vitro and is fully pathogenic in vivo. Journal of virology. 2005 Academic Article GET IT
Times cited: 82
Coronavirus neurovirulence correlates with the ability of the virus to induce proinflammatory cytokine signals from astrocytes and microglia. Journal of virology. 2004 Academic Article GET IT
Times cited: 116
A combination of mutations in the S1 part of the spike glycoprotein gene of coronavirus MHV-A59 abolishes demyelination. Journal of neurovirology. 2004 Academic Article GET IT
Times cited: 4
Coronavirus-induced demyelination occurs in the absence of CD28 costimulatory signals. Journal of neuroimmunology. 2004 Academic Article GET IT
Times cited: 3
Amino acid substitutions within the heptad repeat domain 1 of murine coronavirus spike protein restrict viral antigen spread in the central nervous system. Virology. 2003 Academic Article GET IT
Times cited: 22
Differential induction of apoptosis in demyelinating and nondemyelinating infection by mouse hepatitis virus. Journal of neurovirology. 2002 Academic Article GET IT
Times cited: 15
Neither B cells nor T cells are required for CNS demyelination in mice persistently infected with MHV-A59. Journal of neurovirology. 2002 Academic Article GET IT
Times cited: 40
Microglia in diseases of the central nervous system. Annals of medicine. 2002 Information Resource GET IT
Times cited: 194
Detection of lipoprotein(a) in intraparenchymal cerebral vessels: correlation with vascular pathology and clinical history. Experimental and molecular pathology. 2001 Academic Article GET IT
Times cited: 1
Gene expression of apolipoprotein(a) within the wall of human aorta and carotid arteries. Atherosclerosis. 2001 Academic Article GET IT
Times cited: 17
Sequence analysis of the S gene of recombinant MHV-2/A59 coronaviruses reveals three candidate mutations associated with demyelination and hepatitis. Journal of neurovirology. 2001 Academic Article GET IT
Times cited: 22
Mouse hepatitis virus type-2 infection in mice: an experimental model system of acute meningitis and hepatitis. Experimental and molecular pathology. 2001 Academic Article GET IT
Times cited: 25
CXCR3 expression in human central nervous system diseases. Neuropathology and applied neurobiology. 2001 Academic Article GET IT
Times cited: 67
Murine coronavirus spike protein determines the ability of the virus to replicate in the liver and cause hepatitis. Journal of virology. 2001 Academic Article GET IT
Times cited: 71
Cutting edge: C3, a key component of complement activation, is not required for the development of myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis in mice. Journal of immunology (Baltimore, Md. : 1950). 2001 Academic Article GET IT
Times cited: 70
Expression pattern of CXCR3, CXCR4, and CCR3 chemokine receptors in the developing human brain. Journal of neuropathology and experimental neurology. 2001 Academic Article GET IT
Times cited: 38
Modulation of susceptibility and resistance to an autoimmune model of multiple sclerosis in prototypically susceptible and resistant strains by neutralization of interleukin-12 and interleukin-4, respectively. Clinical immunology (Orlando, Fla.). 2001 Academic Article GET IT
Times cited: 42
The role of B cells in mouse hepatitis virus infection and pathology. Advances in experimental medicine and biology. 2001 Academic Article GET IT
Times cited: 2
Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia. Experimental and molecular pathology. 2000 Academic Article GET IT
Times cited: 135
Demyelination determinants map to the spike glycoprotein gene of coronavirus mouse hepatitis virus. Journal of virology. 2000 Academic Article GET IT
Times cited: 96
Characterization of experimental spinal cord injury with magnetization transfer ratio histograms. Journal of magnetic resonance imaging : JMRI. 2000 Academic Article GET IT
Times cited: 9
Experimental allergic neuritis in the SJL/J mouse: induction of severe and reproducible disease with bovine peripheral nerve myelin and pertussis toxin with or without interleukin-12. Journal of neuroimmunology. 2000 Academic Article GET IT
Times cited: 28
Differential cytokine and chemokine production characterizes experimental autoimmune meningitis and experimental autoimmune encephalomyelitis. Clinical immunology (Orlando, Fla.). 2000 Academic Article GET IT
Times cited: 9
Anterior uveitis in murine relapsing experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS). Current eye research. 2000 Academic Article GET IT
Times cited: 16
Nidovirus infections: experimental model systems of human neurologic diseases. Journal of neuropathology and experimental neurology. 1999 Information Resource GET IT
Times cited: 19
Pathogenesis of chimeric MHV4/MHV-A59 recombinant viruses: the murine coronavirus spike protein is a major determinant of neurovirulence. Journal of virology. 1999 Academic Article GET IT
Times cited: 147
Experimental autoimmune meningitis: a novel neurological disease in CD28-deficient mice. Clinical immunology (Orlando, Fla.). 1999 Academic Article GET IT
Times cited: 16
Cellular reservoirs for coronavirus infection of the brain in beta2-microglobulin knockout mice. Pathobiology : journal of immunopathology, molecular and cellular biology. 1999 Academic Article GET IT
Times cited: 14
Targeted recombination within the spike gene of murine coronavirus mouse hepatitis virus-A59: Q159 is a determinant of hepatotropism. Journal of virology. 1998 Academic Article GET IT
Times cited: 67
Antibodies against IL-12 prevent superantigen-induced and spontaneous relapses of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). 1998 Academic Article GET IT
Times cited: 126
The effect of human herpesvirus-6 (HHV-6) on cultured human neural cells: oligodendrocytes and microglia. Journal of neurovirology. 1998 Academic Article GET IT
Times cited: 71
Dependence of apparent diffusion coefficients on axonal spacing, membrane permeability, and diffusion time in spinal cord white matter. Journal of magnetic resonance imaging : JMRI. 1998 Academic Article GET IT
Times cited: 82
Coronavirus MHV-A59 causes upregulation of interferon-beta RNA in primary glial cell cultures. Advances in experimental medicine and biology. 1998 Academic Article GET IT
Times cited: 10
Targeted recombination between MHV-2 and MHV-A59 to study neurotropic determinants of MHV. Advances in experimental medicine and biology. 1998 Academic Article GET IT
Times cited: 5
The C12 mutant of MHV-A59 is very weakly demyelinating and has five amino acid substitutions restricted to the spike and replicase genes. Advances in experimental medicine and biology. 1998 Academic Article GET IT
Times cited: 2
The pathogenesis of MHV nucleocapsid gene chimeric viruses. Advances in experimental medicine and biology. 1998 Academic Article GET IT
Times cited: 8
Altered pathogenesis of a mutant of the murine coronavirus MHV-A59 is associated with a Q159L amino acid substitution in the spike protein. Virology. 1997 Academic Article GET IT
Times cited: 55
OlP-1, a novel protein that distinguishes early oligodendrocyte precursors. Journal of neuroscience research. 1997 Academic Article GET IT
Times cited: 1
CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons. The American journal of pathology. 1997 Academic Article GET IT
Times cited: 220
Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis. The Journal of experimental medicine. 1997 Academic Article GET IT
Times cited: 174
Defensin stimulates the binding of lipoprotein (a) to human vascular endothelial and smooth muscle cells. Blood. 1997 Academic Article GET IT
Times cited: 65
CD4+ and CD8+ T cells are not major effectors of mouse hepatitis virus A59-induced demyelinating disease. Journal of neurovirology. 1997 Academic Article GET IT
Times cited: 32
Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation. Journal of virology. 1997 Academic Article GET IT
Times cited: 174
Suppression of experimental autoimmune neuritis by phosphodiesterase inhibitor pentoxifylline. Journal of the neurological sciences. 1996 Academic Article GET IT
Times cited: 21
Syncytia formation induced by coronavirus infection is associated with fragmentation and rearrangement of the Golgi apparatus. Virology. 1996 Academic Article GET IT
Times cited: 52
Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry. AIDS (London, England). 1996 Academic Article GET IT
Times cited: 376
Identification of Epstein-Barr virus lytic activity in post-transplantation lymphoproliferative disease. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 1996 Academic Article GET IT
Times cited: 54
HIV-1 infection of cultured human adult oligodendrocytes. Virology. 1996 Academic Article GET IT
Times cited: 61
Demyelination following transfer of human lymphocytes into mice with severe combined immunodeficiency. Pathobiology : journal of immunopathology, molecular and cellular biology. 1996 Academic Article GET IT
Times cited: 3
Apolipoprotein(a) deposition in atherosclerotic plaques of cerebral vessels. A potential role for endothelial cells in lesion formation. The American journal of pathology. 1995 Academic Article GET IT
Times cited: 52
Mouse hepatitis virus A59-induced demyelination can occur in the absence of CD8+ T cells. Microbial pathogenesis. 1995 Academic Article GET IT
Times cited: 42
A mucin-like glycoprotein identified by MAG (mouse ascites Golgi) antibodies. Menstrual cycle-dependent localization in human endometrium. The American journal of pathology. 1995 Academic Article GET IT
Times cited: 41
Primary central nervous system lymphoma following transfer of human peripheral blood lymphocytes into SCID mice. Pathobiology : journal of immunopathology, molecular and cellular biology. 1995 Academic Article GET IT
Times cited: 2
A point mutation in the env gene of a murine leukemia virus induces syncytium formation and neurologic disease. Journal of virology. 1994 Academic Article GET IT
Times cited: 48
Intracerebral hemorrhages and infarction induced by a murine leukemia virus is influenced by host determinants within endothelial cells. Virology. 1994 Academic Article GET IT
Times cited: 12
Polarity of processes with Golgi apparatus in a subpopulation of type I astrocytes. Brain research. 1994 Academic Article GET IT
Times cited: 4
MHV-A59 fusion mutants are attenuated and display altered hepatotropism. Virology. 1994 Academic Article GET IT
Pathogenesis of cerebral infarction and hemorrhage induced by a murine leukemia virus. Laboratory investigation; a journal of technical methods and pathology. 1994 Academic Article GET IT
Times cited: 16
Intracerebral hemorrhages and syncytium formation induced by endothelial cell infection with a murine leukemia virus. Journal of virology. 1993 Academic Article GET IT
Times cited: 35
Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging. Radiology. 1992 Academic Article GET IT
Times cited: 621
Monoclonal antibody 2H1 detects a 60-65 KD membrane polypeptide of the rough endoplasmic reticulum of neurons and selectively stains cells of several rat tissues. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 1991 Academic Article GET IT
Times cited: 5
Protection of neonatal mice from fatal reovirus infection by immune serum and gut derived lymphocytes. Advances in experimental medicine and biology. 1991 Academic Article GET IT
Times cited: 9
Determinants of coronavirus MHV pathogenesis are localized to 3' portions of the genome as determined by ribonucleic acid-ribonucleic acid recombination. Laboratory investigation; a journal of technical methods and pathology. 1990 Academic Article GET IT
Times cited: 31
Passive immunity to fatal reovirus serotype 3-induced meningoencephalitis mediated by both secretory and transplacental factors in neonatal mice. Journal of virology. 1990 Academic Article GET IT
Times cited: 32
Effects of lipofuscin on in situ hybridization in human neuronal tissue. Journal of virological methods. 1989 Academic Article GET IT
Times cited: 5
Induction of MHC class I antigens on glial cells is dependent on persistent mouse hepatitis virus infection. Journal of neuroimmunology. 1989 Academic Article GET IT
Times cited: 27
Latent herpes simplex virus type 1 transcription in human trigeminal ganglia. Journal of virology. 1988 Academic Article GET IT
Times cited: 81
Tumor necrosis factor induces expression of MHC class I antigens on mouse astrocytes. Journal of neuroimmunology. 1988 Academic Article GET IT
Times cited: 88
Induction of glial cell MHC antigen expression in neurotropic coronavirus infections. Characterization of the H-2-inducing soluble factor elaborated by infected brain cells. Journal of immunology (Baltimore, Md. : 1950). 1988 Academic Article GET IT
Times cited: 41
Latent herpes simplex virus type 1 transcripts in peripheral and central nervous system tissues of mice map to similar regions of the viral genome. Journal of virology. 1988 Academic Article GET IT
Times cited: 124
Limbic encephalitis after inhalation of a murine coronavirus. Laboratory investigation; a journal of technical methods and pathology. 1988 Academic Article GET IT
Times cited: 87
Tumor necrosis factor induces expression of MHC class I antigens on mouse astrocytes. Annals of the New York Academy of Sciences. 1988 Academic Article GET IT
Times cited: 9
Coronavirus mouse hepatitis virus (MHV)-A59 causes a persistent, productive infection in primary glial cell cultures. Microbial pathogenesis. 1987 Academic Article GET IT
Times cited: 51
RNA from an immediate early region of the type 1 herpes simplex virus genome is present in the trigeminal ganglia of latently infected mice. Proceedings of the National Academy of Sciences of the United States of America. 1987 Academic Article GET IT
Times cited: 183
Expression of MHC class I genes in mouse hepatitis virus (MHV-A59) infection and in multiple sclerosis. Advances in experimental medicine and biology. 1987 Academic Article GET IT
Times cited: 9
Epidural haemangiomas during pregnancy. Journal of neurology, neurosurgery, and psychiatry. 1986 Academic Article GET IT
Times cited: 38
Coronavirus infection induces H-2 antigen expression on oligodendrocytes and astrocytes. Science (New York, N.Y.). 1986 Academic Article GET IT
Times cited: 131
The organ tropism of mouse hepatitis virus A59 in mice is dependent on dose and route of inoculation. Laboratory animal science. 1986 Academic Article GET IT
Times cited: 79
Infection of the basal ganglia by a murine coronavirus. Science (New York, N.Y.). 1985 Academic Article GET IT
Times cited: 47
Persistence of mouse hepatitis virus A59 RNA in a slow virus demyelinating infection in mice as detected by in situ hybridization. Journal of virology. 1984 Academic Article GET IT
Times cited: 82
Experimental demyelination produced by the A59 strain of mouse hepatitis virus. Neurology. 1984 Academic Article GET IT
Times cited: 137
Detection of MHV-A59 RNA by in situ hybridization. Advances in experimental medicine and biology. 1984 Academic Article GET IT
Times cited: 6
MHV-A59 pathogenesis in mice. Advances in experimental medicine and biology. 1984 Academic Article GET IT
Times cited: 10

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Background

education and training

M.D., Technion-Israel Institute of Technology, Faculty of Medicine (Israel) 1978

VIVO Weill Cornell Medical College

Ehud Lavi Professor Emeritus of Pathology and Laboratory Medicine

Publications

selected publications

Background

education and training

Contact

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