selected publications
- A cell-autonomous role for border-associated macrophages in ApoE4 neurovascular dysfunction and susceptibility to white matter injury. Nature neuroscience. 2024 Academic Article GET IT
- Tumor necrosis factor alpha induces NOX2-dependent reactive oxygen species production in hypothalamic paraventricular nucleus neurons following angiotensin II infusion. Neurochemistry international. 2024 Academic Article GET IT
- Meningeal interleukin-17-producing T cells mediate cognitive impairment in a mouse model of salt-sensitive hypertension. Nature neuroscience. 2023 Academic Article GET IT
- Estrogen receptor beta activity contributes to both tumor necrosis factor alpha expression in the hypothalamic paraventricular nucleus and the resistance to hypertension following angiotensin II in female mice. Neurochemistry international. 2022 Academic Article GET IT
- Angiotensin II infusion results in both hypertension and increased AMPA GluA1 signaling in hypothalamic paraventricular nucleus of male but not female mice. Neuroscience. 2022 Academic Article GET IT
- Adolescent administration of Δ9-THC decreases the expression and function of muscarinic-1 receptors in prelimbic prefrontal cortical neurons of adult male mice. IBRO neuroscience reports. 2021 Academic Article GET IT
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Estrogen Receptor β Contributes to Both Hypertension and Hypothalamic Plasticity in a Mouse Model of Peri-Menopause.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2021
Academic Article
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Times cited: 20 -
Tumor Necrosis Factor α Receptor Type 1 Activation in the Hypothalamic Paraventricular Nucleus Contributes to Glutamate Signaling and Angiotensin II-Dependent Hypertension.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2020
Academic Article
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Times cited: 21 -
tPA Deficiency Underlies Neurovascular Coupling Dysfunction by Amyloid-β.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2020
Academic Article
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Times cited: 34 -
Tau induces PSD95-neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration.
Nature neuroscience.
2020
Academic Article
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Times cited: 71 -
Amyloid-Beta Modulates Low-Threshold Activated Voltage-Gated L-Type Calcium Channels of Arcuate Neuropeptide Y Neurons Leading to Calcium Dysregulation and Hypothalamic Dysfunction.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2019
Academic Article
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Times cited: 36 -
Chronic adolescent exposure to ∆9-tetrahydrocannabinol decreases NMDA current and extrasynaptic plasmalemmal density of NMDA GluN1 subunits in the prelimbic cortex of adult male mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2019
Academic Article
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Times cited: 15 -
Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function.
Nature communications.
2018
Academic Article
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Times cited: 107 -
Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response.
Nature neuroscience.
2018
Academic Article
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Times cited: 243 -
New generations of dihydropyridines for treatment of hypertension.
Journal of geriatric cardiology : JGC.
2017
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Times cited: 56 -
Redistribution of NMDA Receptors in Estrogen-Receptor-β-Containing Paraventricular Hypothalamic Neurons following Slow-Pressor Angiotensin II Hypertension in Female Mice with Accelerated Ovarian Failure.
Neuroendocrinology.
2016
Academic Article
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Times cited: 23 -
Endothelial Dysfunction and Amyloid-β-Induced Neurovascular Alterations.
Cellular and molecular neurobiology.
2015
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Times cited: 91 -
NMDA Receptor Plasticity in the Hypothalamic Paraventricular Nucleus Contributes to the Elevated Blood Pressure Produced by Angiotensin II.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2015
Academic Article
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Times cited: 45 -
Female protection from slow-pressor effects of angiotensin II involves prevention of ROS production independent of NMDA receptor trafficking in hypothalamic neurons expressing angiotensin 1A receptors.
Synapse (New York, N.Y.).
2015
Academic Article
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Times cited: 29 -
The key role of transient receptor potential melastatin-2 channels in amyloid-β-induced neurovascular dysfunction.
Nature communications.
2014
Academic Article
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Times cited: 107 -
Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2014
Academic Article
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Times cited: 72 -
COX-1-derived PGE2 and PGE2 type 1 receptors are vital for angiotensin II-induced formation of reactive oxygen species and Ca(2+) influx in the subfornical organ.
American journal of physiology. Heart and circulatory physiology.
2013
Academic Article
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Times cited: 30 -
Angiotensin II slow-pressor hypertension enhances NMDA currents and NOX2-dependent superoxide production in hypothalamic paraventricular neurons.
American journal of physiology. Regulatory, integrative and comparative physiology.
2013
Academic Article
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Times cited: 55 -
Membrane trafficking of NADPH oxidase p47(phox) in paraventricular hypothalamic neurons parallels local free radical production in angiotensin II slow-pressor hypertension.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2013
Academic Article
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Times cited: 38 -
Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.
Cancer research.
2013
Academic Article
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Times cited: 38 -
ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension.
The Journal of clinical investigation.
2012
Academic Article
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Times cited: 130 -
Distribution of angiotensin type 1a receptor-containing cells in the brains of bacterial artificial chromosome transgenic mice.
Neuroscience.
2012
Academic Article
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Times cited: 54 -
Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+ currents in NTS neurons.
American journal of physiology. Regulatory, integrative and comparative physiology.
2012
Academic Article
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Times cited: 24 -
Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signaling in the subfornical organ of the brain.
Hypertension (Dallas, Tex. : 1979).
2012
Academic Article
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Times cited: 49 - The link between angiotensin II-mediated anxiety and mood disorders with NADPH oxidase-induced oxidative stress. International journal of physiology, pathophysiology and pharmacology. 2012 Academic Article GET IT
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Prohibitin reduces mitochondrial free radical production and protects brain cells from different injury modalities.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2012
Academic Article
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Times cited: 77 -
Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α.
Cancer research.
2011
Academic Article
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Times cited: 81 -
Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta.
Proceedings of the National Academy of Sciences of the United States of America.
2011
Academic Article
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Times cited: 135 -
Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2010
Academic Article
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Times cited: 61 -
Distribution of estrogen receptor β containing cells in the brains of bacterial artificial chromosome transgenic mice.
Brain research.
2010
Academic Article
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Times cited: 61 -
The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice.
Regenerative medicine.
2010
Academic Article
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Times cited: 22 -
Epimorphic regeneration approach to tissue replacement in adult mammals.
Proceedings of the National Academy of Sciences of the United States of America.
2009
Academic Article
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Times cited: 135 -
NMDA receptor activation increases free radical production through nitric oxide and NOX2.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2009
Academic Article
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Times cited: 211 -
The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells.
Biochemical and biophysical research communications.
2008
Academic Article
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Times cited: 37 -
Sex differences in angiotensin signaling in bulbospinal neurons in the rat rostral ventrolateral medulla.
American journal of physiology. Regulatory, integrative and comparative physiology.
2008
Academic Article
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Times cited: 30 -
Key role of tissue plasminogen activator in neurovascular coupling.
Proceedings of the National Academy of Sciences of the United States of America.
2008
Academic Article
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Times cited: 82 -
Heat shock proteins and p53 play a critical role in K+ channel-mediated tumor cell proliferation and apoptosis.
Apoptosis : an international journal on programmed cell death.
2007
Academic Article
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Times cited: 37 -
Subcellular localization of nicotinamide adenine dinucleotide phosphate oxidase subunits in neurons and astroglia of the rat medial nucleus tractus solitarius: relationship with tyrosine hydroxylase immunoreactive neurons.
Neuroscience.
2006
Academic Article
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Times cited: 27 -
Nox2, Ca2+, and protein kinase C play a role in angiotensin II-induced free radical production in nucleus tractus solitarius.
Hypertension (Dallas, Tex. : 1979).
2006
Academic Article
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Times cited: 92 -
Evidence that estrogen directly and indirectly modulates C1 adrenergic bulbospinal neurons in the rostral ventrolateral medulla.
Brain research.
2006
Academic Article
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Times cited: 46 -
Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity.
Nature medicine.
2006
Academic Article
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Times cited: 313 -
Distinct rat neurohypophysial nerve terminal populations identified by size, electrophysiological properties and neuropeptide content.
Brain research.
2004
Academic Article
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Times cited: 7 -
Exogenous NADPH increases cerebral blood flow through NADPH oxidase-dependent and -independent mechanisms.
Arteriosclerosis, thrombosis, and vascular biology.
2004
Academic Article
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Times cited: 50 -
NADPH oxidase contributes to angiotensin II signaling in the nucleus tractus solitarius.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2004
Academic Article
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Times cited: 161 -
Angiotensin II attenuates functional hyperemia in the mouse somatosensory cortex.
American journal of physiology. Heart and circulatory physiology.
2003
Academic Article
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Times cited: 73 -
Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.
Molecular pharmacology.
2003
Academic Article
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Times cited: 77 -
Adenosine inhibition via A(1) receptor of N-type Ca(2+) current and peptide release from isolated neurohypophysial terminals of the rat.
The Journal of physiology.
2002
Academic Article
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Times cited: 28 -
Evidence for endogenous agmatine in hypothalamo-neurohypophysial tract and its modulation on vasopressin release and Ca2+ channels.
Brain research.
2002
Academic Article
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Times cited: 24 -
Localization of agmatine in vasopressin and oxytocin neurons of the rat hypothalamic paraventricular and supraoptic nuclei.
Experimental neurology.
2001
Academic Article
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Times cited: 38 -
Specific actions of cyanide on membrane potential and voltage-gated ion currents in rostral ventrolateral medulla neurons in rat brainstem slices.
Neuroscience letters.
2001
Academic Article
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Times cited: 21 -
Excitatory versus inhibitory modulation by ATP of neurohypophysial terminal activity in the rat.
Experimental physiology.
2000
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Times cited: 23 -
An R-type Ca(2+) current in neurohypophysial terminals preferentially regulates oxytocin secretion.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1999
Academic Article
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Times cited: 110 -
Rat supraoptic magnocellular neurones show distinct large conductance, Ca2+-activated K+ channel subtypes in cell bodies versus nerve endings.
The Journal of physiology.
1999
Academic Article
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Times cited: 88 -
Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas.
Biochemistry.
1998
Academic Article
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Times cited: 319 -
Voltage dependent calcium and potassium currents in Y-1 adrenocortical cells are unresponsive to ACTH.
Endocrine research.
1997
Academic Article
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Times cited: 5 -
Role of Q-type Ca2+ channels in vasopressin secretion from neurohypophysial terminals of the rat.
The Journal of physiology.
1997
Academic Article
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Times cited: 73 -
Effects of funnel web spider toxin on Ca2+ currents in neurohypophysial terminals.
Brain research.
1994
Academic Article
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Times cited: 19 -
Ethanol directly modulates gating of a dihydropyridine-sensitive Ca2+ channel in neurohypophysial terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1994
Academic Article
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Times cited: 80 -
Effects of toxins on Ca2+ currents and peptide release from nerve terminals.
Annals of the New York Academy of Sciences.
1994
Academic Article
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Times cited: 15 -
Comparison of effects of tetrandrine on ionic channels of isolated rat neurohypophysial terminals and Y1 mouse adrenocortical tumor cells.
Zhongguo yao li xue bao = Acta pharmacologica Sinica.
1993
Academic Article
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Times cited: 13 -
A novel large-conductance Ca(2+)-activated potassium channel and current in nerve terminals of the rat neurohypophysis.
The Journal of physiology.
1992
Academic Article
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Times cited: 49 -
Tetrandrine blocks a slow, large-conductance, Ca(2+)-activated potassium channel besides inhibiting a non-inactivating Ca2+ current in isolated nerve terminals of the rat neurohypophysis.
Pflugers Archiv : European journal of physiology.
1992
Academic Article
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Times cited: 48 -
Sodium channel comodification with full activator reveals veratridine reaction dynamics.
Molecular pharmacology.
1990
Academic Article
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Times cited: 21 -
Interaction between DPI 201-106 enantiomers at the cardiac sodium channel.
Molecular pharmacology.
1990
Academic Article
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Times cited: 30