selected publications
- Transgelin 2 guards T cell lipid metabolism and antitumour function. Nature. 2024 Academic Article GET IT
- High-grade serous ovarian cancer development and anti-PD-1 resistance is driven by IRE1α activity in neutrophils. Oncoimmunology. 2024 Academic Article GET IT
- Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve immunotherapy. Nature immunology. 2024 Academic Article GET IT
- Enterococcal-host interactions in the gastrointestinal tract and beyond. FEMS microbes. 2024 Review GET IT
- High-grade serous ovarian cancer development and anti-PD-1 resistance is driven by IRE1α activity in neutrophils. 2024 GET IT
- Iron Chelation Therapy Elicits Innate Immune Control of Metastatic Ovarian Cancer. Cancer discovery. 2024 Academic Article GET IT
- Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function. 2023 GET IT
- Impaired T cell IRE1α-XBP1 signaling directs inflammation in experimental Heart Failure with Preserved Ejection Fraction. The Journal of clinical investigation. 2023 Academic Article GET IT
- Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve checkpoint blockade. 2023 GET IT
- Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis. The Journal of clinical investigation. 2023 Academic Article GET IT
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Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Cell death and differentiation.
2023
Review
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Times cited: 133 - Control of immune cell function by the unfolded protein response. Nature reviews. Immunology. 2023 Review GET IT
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Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer.
Nature communications.
2023
Academic Article
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Times cited: 16 - Remodeling of the Enterococcal Cell Envelope during Surface Penetration Promotes Intrinsic Resistance to Stress. mBio. 2022 Academic Article GET IT
- Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responses. The Journal of experimental medicine. 2022 Academic Article GET IT
- Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses. Cancer cell. 2022 Academic Article GET IT
- Decoding endoplasmic reticulum stress signals in cancer cells and antitumor immunity. Trends in cancer. 2022 Review GET IT
- High-Fat Diet-Induced Obesity Alters Dendritic Cell Homeostasis by Enhancing Mitochondrial Fatty Acid Oxidation. Journal of immunology (Baltimore, Md. : 1950). 2022 Academic Article GET IT
- Fungal Patterns Induce Cytokine Expression through Fluxes of Metabolic Intermediates That Support Glycolysis and Oxidative Phosphorylation. Journal of immunology (Baltimore, Md. : 1950). 2022 Academic Article GET IT
- Tumor-derived Lysophosphatidic Acid Blunts Protective Type-I Interferon Responses in Ovarian Cancer. Cancer discovery. 2022 Academic Article GET IT
- Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. 2022 Academic Article GET IT
- Methods and protocols for chemotherapy-induced peripheral neuropathy (CIPN) mouse models using paclitaxel. 2022 GET IT
- Engineered bacteria recycle tumor metabolic waste to boost immunotherapy. Cell host & microbe. 2021 Academic Article GET IT
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Endoplasmic reticulum stress signals in the tumour and its microenvironment.
Nature reviews. Cancer.
2020
Information Resource
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Times cited: 658 -
Dietary Fructose Alters the Composition, Localization, and Metabolism of Gut Microbiota in Association With Worsening Colitis.
Cellular and molecular gastroenterology and hepatology.
2020
Academic Article
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Times cited: 65 -
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells.
Science (New York, N.Y.).
2020
Academic Article
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Times cited: 94 -
The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling.
Immunity.
2020
Academic Article
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Times cited: 136 -
The impact of endoplasmic reticulum stress responses in dendritic cell immunobiology.
International review of cell and molecular biology.
2019
Article
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Times cited: 4 -
IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain.
Science (New York, N.Y.).
2019
Academic Article
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Times cited: 26 -
Dendritic Cell Metabolism and Function in Tumors.
Trends in immunology.
2019
Information Resource
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Times cited: 34 -
Somatic mutations and cell identity linked by Genotyping of Transcriptomes.
Nature.
2019
Academic Article
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Times cited: 181 -
Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphocholine Lipids Support Cytokine Induction in Response to Fungal Patterns.
Cell reports.
2019
Academic Article
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Times cited: 13 -
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications.
2019
Academic Article
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Times cited: 98 -
PolyGlcNAc-containing exopolymers enable surface penetration by non-motile Enterococcus faecalis.
PLoS pathogens.
2019
Academic Article
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Times cited: 28 -
IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity.
Nature.
2018
Academic Article
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Times cited: 276 -
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.
Nature cell biology.
2018
Academic Article
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Times cited: 1171 -
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Cell death and differentiation.
2018
Information Resource
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Times cited: 4419 -
Endoplasmic Reticulum Stress Sensor IRE1α Enhances IL-23 Expression by Human Dendritic Cells.
Frontiers in immunology.
2017
Academic Article
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Times cited: 29 -
Dendritic cell rehab: new strategies to unleash therapeutic immunity in ovarian cancer.
Cancer immunology, immunotherapy : CII.
2017
Information Resource
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Times cited: 13 -
Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer.
Cell.
2017
Information Resource
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Times cited: 637 -
Unfolding anti-tumor immunity: ER stress responses sculpt tolerogenic myeloid cells in cancer.
Journal for immunotherapy of cancer.
2017
Information Resource
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Times cited: 72 -
State-of-the-art of regulatory dendritic cells in cancer.
Pharmacology & therapeutics.
2016
Information Resource
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Times cited: 41 - Targeting abnormal ER stress responses in tumors: A new approach to cancer immunotherapy. Oncoimmunology. 2015 Academic Article GET IT
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IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection.
Nature communications.
2015
Academic Article
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Times cited: 58 -
ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis.
Cell.
2015
Academic Article
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Times cited: 649 -
Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment.
Cancer research.
2013
Academic Article
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Times cited: 90 - Reprogramming immune responses via microRNA modulation. microRNA diagnostics and therapeutics. 2013 Academic Article GET IT
- Good things come in small packages: Therapeutic anti-tumor immunity induced by microRNA nanoparticles. Oncoimmunology. 2012 Academic Article GET IT
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BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.
The EMBO journal.
2012
Academic Article
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Times cited: 99 -
Ovarian cancer progression is controlled by phenotypic changes in dendritic cells.
The Journal of experimental medicine.
2012
Academic Article
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Times cited: 269 -
Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer.
Cancer research.
2012
Academic Article
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Times cited: 141 - It never rains but it pours: potential role of butyrophilins in inhibiting anti-tumor immune responses. Cell cycle (Georgetown, Tex.). 2011 Editorial Article GET IT
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Antifungal mechanisms by which a novel Pseudomonas aeruginosa phenazine toxin kills Candida albicans in biofilms.
Molecular microbiology.
2010
Academic Article
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Times cited: 122 -
CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells.
Oncotarget.
2010
Academic Article
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Times cited: 63 -
CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950).
2010
Academic Article
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Times cited: 69 - Blocking ovarian cancer progression by targeting tumor microenvironmental leukocytes. Cell cycle (Georgetown, Tex.). 2010 Information Resource GET IT
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Nanomolecular targeting of dendritic cells for ovarian cancer therapy.
Future oncology (London, England).
2009
Editorial Article
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Times cited: 16 -
In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells.
Cancer research.
2009
Academic Article
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Times cited: 118 -
CCL5-mediated endogenous antitumor immunity elicited by adoptively transferred lymphocytes and dendritic cell depletion.
Cancer research.
2009
Academic Article
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Times cited: 52 -
Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity.
The Journal of clinical investigation.
2009
Academic Article
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Times cited: 194 -
Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity.
Cancer research.
2008
Academic Article
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Times cited: 100 -
PILAR is a novel modulator of human T-cell expansion.
Blood.
2008
Academic Article
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Times cited: 33