selected publications
- Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site. Science immunology. 2024 Academic Article GET IT
- Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques. Science immunology. 2024 Academic Article GET IT
- The significance of antigen-antibody-binding avidity in clinical diagnosis. Critical reviews in clinical laboratory sciences. 2024 Review GET IT
- Fusion peptide-directed antibodies: Humoral armor against HIV-1 infection. Science translational medicine. 2024 Review GET IT
- Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques. 2023 GET IT
- Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization. PLoS pathogens. 2023 Academic Article GET IT
- Correction: HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers. 2023 GET IT
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Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.
Retrovirology.
2023
Academic Article
GET IT
Times cited: 2 - Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions. Cell reports. Medicine. 2023 Academic Article GET IT
- Longitudinal antibody response kinetics following SARS-CoV-2 mRNA vaccination in pregnant and non-pregnant persons. American journal of obstetrics & gynecology MFM. 2022 Academic Article GET IT
- Measurements of SARS-CoV-2 antibody dissociation rate constant by chaotrope-free biolayer interferometry in serum of COVID-19 convalescent patients. Biosensors & bioelectronics. 2022 Academic Article GET IT
- The glycan hole area of HIV-1 envelope trimers contributes prominently to the induction of autologous neutralization. Journal of virology. 2021 Academic Article GET IT
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TOP-Plus Is a Versatile Biosensor Platform for Monitoring SARS-CoV-2 Antibody Durability.
Clinical chemistry.
2021
Academic Article
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Times cited: 11 -
Serologic response to mRNA COVID-19 vaccination in lymphoma patients.
American journal of hematology.
2021
Letter
GET IT
Times cited: 24 - Antibodies from Rabbits Immunized with HIV-1 Clade B SOSIP Trimers Can Neutralize Multiple Clade B Viruses by Destabilizing the Envelope Glycoprotein. Journal of virology. 2021 Academic Article GET IT
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Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva.
Pathogens & immunity.
2021
Academic Article
GET IT
Times cited: 83 -
Postconvalescent SARS-CoV-2 IgG and Neutralizing Antibodies are Elevated in Individuals with Poor Metabolic Health.
The Journal of clinical endocrinology and metabolism.
2021
Academic Article
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Times cited: 23 -
Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike.
Cell reports.
2021
Academic Article
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Times cited: 3 -
Association of Age With SARS-CoV-2 Antibody Response.
JAMA network open.
2021
Academic Article
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Times cited: 139 -
Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles.
NPJ vaccines.
2021
Academic Article
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Times cited: 31 -
Testing-on-a-probe biosensors reveal association of early SARS-CoV-2 total antibodies and surrogate neutralizing antibodies with mortality in COVID-19 patients.
Biosensors & bioelectronics.
2021
Academic Article
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Times cited: 18 -
High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post-HIV Env trimer vaccination.
eLife.
2021
Academic Article
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Times cited: 12 -
Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers.
Journal of virology.
2020
Academic Article
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Times cited: 13 -
COVID-19 Vaccines: "Warp Speed" Needs Mind Melds, Not Warped Minds.
Journal of virology.
2020
Information Resource
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Times cited: 67 -
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
PLoS pathogens.
2020
Academic Article
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Times cited: 43 -
Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
eLife.
2020
Academic Article
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Times cited: 100 - Seminal analyses of HIV-1 transmission. EBioMedicine. 2020 Article GET IT
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Env Exceptionalism: Why Are HIV-1 Env Glycoproteins Atypical Immunogens?.
Cell host & microbe.
2020
Information Resource
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Times cited: 39 -
Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin.
Journal of virology.
2020
Academic Article
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Times cited: 26 - SOS and IP Modifications Predominantly Affect the Yield but Not Other Properties of SOSIP.664 HIV-1 Env Glycoprotein Trimers. Journal of virology. 2019 Academic Article GET IT
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Antibody Responses Elicited by Immunization with BG505 Trimer Immune Complexes.
Journal of virology.
2019
Academic Article
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Times cited: 13 -
Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.
Nature communications.
2019
Academic Article
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Times cited: 129 -
Non-cognate ligands of Procrustean paratopes as potential vaccine components.
EBioMedicine.
2019
Article
GET IT
Times cited: 3 -
Optimizing the production and affinity purification of HIV-1 envelope glycoprotein SOSIP trimers from transiently transfected CHO cells.
PloS one.
2019
Academic Article
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Times cited: 16 -
Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes.
Journal of virology.
2019
Academic Article
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Times cited: 54 -
Collusion between neutralizing antibodies and other immune factions in the destruction of adenoviral vectors.
Proceedings of the National Academy of Sciences of the United States of America.
2018
Article
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Times cited: 3 -
Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro.
Journal of virology.
2018
Academic Article
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Times cited: 31 -
Immunogenicity in Rabbits of HIV-1 SOSIP Trimers from Clades A, B, and C, Given Individually, Sequentially, or in Combination.
Journal of virology.
2018
Academic Article
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Times cited: 60 -
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
PLoS pathogens.
2018
Academic Article
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Times cited: 79 -
cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.
Biotechnology and bioengineering.
2017
Academic Article
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Times cited: 58 -
High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers.
Journal of virology.
2017
Academic Article
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Times cited: 21 -
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.
The Journal of experimental medicine.
2017
Academic Article
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Times cited: 129 -
Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.
Cell reports.
2017
Academic Article
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Times cited: 129 -
HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers.
PloS one.
2017
Academic Article
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Times cited: 14 -
Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers.
Journal of virology.
2017
Academic Article
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Times cited: 39 -
Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes.
Journal of virology.
2017
Academic Article
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Times cited: 25 -
A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure.
Immunity.
2017
Academic Article
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Times cited: 177 -
Recognition of HIV-inactivating peptide triazoles by the recombinant soluble Env trimer, BG505 SOSIP.664.
Proteins.
2017
Academic Article
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Times cited: 7 -
An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability.
Nature microbiology.
2016
Academic Article
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Times cited: 117 -
HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein Spike.
Journal of virology.
2016
Academic Article
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Times cited: 16 -
Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.
PLoS pathogens.
2016
Academic Article
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Times cited: 118 -
Quantitative Correlation between Infectivity and Gp120 Density on HIV-1 Virions Revealed by Optical Trapping Virometry.
The Journal of biological chemistry.
2016
Academic Article
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Times cited: 27 -
Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein.
Cell reports.
2016
Academic Article
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Times cited: 209 -
How to assess the binding strength of antibodies elicited by vaccination against HIV and other viruses.
Expert review of vaccines.
2016
Information Resource
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Times cited: 45 -
Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes.
Cell.
2015
Academic Article
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Times cited: 276 -
Binding of inferred germline precursors of broadly neutralizing HIV-1 antibodies to native-like envelope trimers.
Virology.
2015
Academic Article
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Times cited: 37 -
Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nature communications.
2015
Academic Article
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Times cited: 72 -
Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens.
Proceedings of the National Academy of Sciences of the United States of America.
2015
Academic Article
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Times cited: 105 -
Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.
Journal of virology.
2015
Academic Article
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Times cited: 72 -
Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity.
Journal of virology.
2015
Academic Article
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Times cited: 122 -
Short Communication: Virion Aggregation by Neutralizing and Nonneutralizing Antibodies to the HIV-1 Envelope Glycoprotein.
AIDS research and human retroviruses.
2015
Academic Article
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Times cited: 12 -
Predicting first traversal times for virions and nanoparticles in mucus with slowed diffusion.
Biophysical journal.
2015
Academic Article
GET IT
Times cited: 11 -
HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.
Science (New York, N.Y.).
2015
Academic Article
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Times cited: 422 -
Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.
PLoS pathogens.
2015
Academic Article
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Times cited: 85 -
What Do Chaotrope-Based Avidity Assays for Antibodies to HIV-1 Envelope Glycoproteins Measure?.
Journal of virology.
2015
Academic Article
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Times cited: 23 -
A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.
Journal of virology.
2015
Academic Article
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Times cited: 199 -
Molecular determinants of the ratio of inert to infectious virus particles.
Progress in molecular biology and translational science.
2014
Article
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Times cited: 29 - Neutralization of Virus Infectivity by Antibodies: Old Problems in New Perspectives. Advances in biology. 2014 Academic Article GET IT
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Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.
Nature.
2014
Academic Article
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Times cited: 367 -
Independent evolution of Fc- and Fab-mediated HIV-1-specific antiviral antibody activity following acute infection.
European journal of immunology.
2014
Academic Article
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Times cited: 45 -
Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits.
Retrovirology.
2014
Academic Article
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Times cited: 131 -
Stable 293Â T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies.
Retrovirology.
2014
Academic Article
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Times cited: 45 -
Pharmacokinetics of a CCR5 inhibitor in rhesus macaques following vaginal, rectal and oral application.
The Journal of antimicrobial chemotherapy.
2013
Academic Article
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Times cited: 13 -
Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science (New York, N.Y.).
2013
Academic Article
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Times cited: 579 -
Crystal structure of a soluble cleaved HIV-1 envelope trimer.
Science (New York, N.Y.).
2013
Academic Article
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Times cited: 713 -
Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation.
Proceedings of the National Academy of Sciences of the United States of America.
2013
Academic Article
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Times cited: 154 -
A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies.
PLoS pathogens.
2013
Academic Article
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Times cited: 734 -
Influences on trimerization and aggregation of soluble, cleaved HIV-1 SOSIP envelope glycoprotein.
Journal of virology.
2013
Academic Article
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Times cited: 76 -
Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers.
Journal of virology.
2013
Academic Article
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Times cited: 67 -
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
Nature structural & molecular biology.
2013
Academic Article
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Times cited: 288 -
Clinical adjuvant combinations stimulate potent B-cell responses in vitro by activating dermal dendritic cells.
PloS one.
2013
Academic Article
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Times cited: 14 -
Use of G-protein-coupled and -uncoupled CCR5 receptors by CCR5 inhibitor-resistant and -sensitive human immunodeficiency virus type 1 variants.
Journal of virology.
2013
Academic Article
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Times cited: 32 -
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.
Proceedings of the National Academy of Sciences of the United States of America.
2013
Academic Article
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Times cited: 215 -
Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5.
Journal of virology.
2012
Academic Article
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Times cited: 62 -
Potent induction of antibody-secreting B cells by human dermal-derived CD14+ dendritic cells triggered by dual TLR ligation.
Journal of immunology (Baltimore, Md. : 1950).
2012
Academic Article
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Times cited: 33 -
Pharmacokinetics and efficacy of a vaginally administered maraviroc gel in rhesus macaques.
The Journal of antimicrobial chemotherapy.
2012
Academic Article
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Times cited: 54 -
Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220.
The Journal of antimicrobial chemotherapy.
2012
Academic Article
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Times cited: 29 -
HIV-1 gp120 impairs the induction of B cell responses by TLR9-activated plasmacytoid dendritic cells.
Journal of immunology (Baltimore, Md. : 1950).
2012
Academic Article
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Times cited: 25 -
Good CoP, bad CoP? Interrogating the immune responses to primate lentiviral vaccines.
Retrovirology.
2012
Information Resource
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Times cited: 12 -
The molecular basis of HIV entry.
Cellular microbiology.
2012
Information Resource
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Times cited: 102 -
Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
GET IT
Times cited: 39 -
Effects of sequence changes in the HIV-1 gp41 fusion peptide on CCR5 inhibitor resistance.
Virology.
2012
Academic Article
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Times cited: 15 -
V3 determinants of HIV-1 escape from the CCR5 inhibitors Maraviroc and Vicriviroc.
Virology.
2012
Academic Article
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Times cited: 31 -
Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques.
Antimicrobial agents and chemotherapy.
2012
Academic Article
GET IT
Times cited: 61 -
Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.
Journal of virology.
2011
Academic Article
GET IT
Times cited: 38 -
SHIV-162P3 infection of rhesus macaques given maraviroc gel vaginally does not involve resistant viruses.
PloS one.
2011
Academic Article
GET IT
Times cited: 13 -
Env-glycoprotein heterogeneity as a source of apparent synergy and enhanced cooperativity in inhibition of HIV-1 infection by neutralizing antibodies and entry inhibitors.
Virology.
2011
Academic Article
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Times cited: 18 -
Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc.
Journal of controlled release : official journal of the Controlled Release Society.
2011
Academic Article
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Times cited: 49 -
Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice.
AIDS research and human retroviruses.
2011
Academic Article
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Times cited: 28 -
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures.
Proceedings of the National Academy of Sciences of the United States of America.
2011
Academic Article
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Times cited: 137 -
Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody.
Proceedings of the National Academy of Sciences of the United States of America.
2011
Academic Article
GET IT
Times cited: 227 - Inhibition of p53 by adenovirus type 12 E1B-55K deregulates cell cycle control and sensitizes tumor cells to genotoxic agents. Journal of virology. 2011 Academic Article GET IT
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Multiple CCR5 conformations on the cell surface are used differentially by human immunodeficiency viruses resistant or sensitive to CCR5 inhibitors.
Journal of virology.
2011
Academic Article
GET IT
Times cited: 54 -
How can HIV-type-1-Env immunogenicity be improved to facilitate antibody-based vaccine development?.
AIDS research and human retroviruses.
2011
Information Resource
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Times cited: 61 -
Resistance of a human immunodeficiency virus type 1 isolate to a small molecule CCR5 inhibitor can involve sequence changes in both gp120 and gp41.
Virology.
2011
Academic Article
GET IT
Times cited: 21 -
Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor.
The Journal of infectious diseases.
2010
Academic Article
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Times cited: 126 -
IgG subclass profiles in infected HIV type 1 controllers and chronic progressors and in uninfected recipients of Env vaccines.
AIDS research and human retroviruses.
2010
Academic Article
GET IT
Times cited: 96 -
Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers.
Proceedings of the National Academy of Sciences of the United States of America.
2009
Academic Article
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Times cited: 230 -
Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry.
PLoS pathogens.
2009
Academic Article
GET IT
Times cited: 62 -
Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo.
Virology.
2009
Academic Article
GET IT
Times cited: 45 -
Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities.
Virology.
2009
Academic Article
GET IT
Times cited: 37 -
Resistance to CCR5 inhibitors caused by sequence changes in the fusion peptide of HIV-1 gp41.
Proceedings of the National Academy of Sciences of the United States of America.
2009
Academic Article
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Times cited: 86 -
Tropism-independent protection of macaques against vaginal transmission of three SHIVs by the HIV-1 fusion inhibitor T-1249.
Proceedings of the National Academy of Sciences of the United States of America.
2008
Academic Article
GET IT
Times cited: 41 -
AIDS/HIV. A STEP into darkness or light?.
Science (New York, N.Y.).
2008
Article
GET IT
Times cited: 42 -
Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission.
Annual review of medicine.
2008
Information Resource
GET IT
Times cited: 156 -
N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus.
Virology.
2007
Academic Article
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Times cited: 24 - HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells. PLoS pathogens. 2007 Academic Article GET IT
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Modeling how many envelope glycoprotein trimers per virion participate in human immunodeficiency virus infectivity and its neutralization by antibody.
Virology.
2007
Academic Article
GET IT
Times cited: 72 -
Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands.
Virology.
2007
Academic Article
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Times cited: 46 -
Entry inhibitor-based microbicides are active in vitro against HIV-1 isolates from multiple genetic subtypes.
Virology.
2007
Academic Article
GET IT
Times cited: 31 -
A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120.
Virology.
2006
Academic Article
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Times cited: 85 -
Specific amino acids in the N-terminus of the gp41 ectodomain contribute to the stabilization of a soluble, cleaved gp140 envelope glycoprotein from human immunodeficiency virus type 1.
Virology.
2006
Academic Article
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Times cited: 39 -
Dominant-negative effect of hetero-oligomerization on the function of the human immunodeficiency virus type 1 envelope glycoprotein complex.
Virology.
2006
Academic Article
GET IT
Times cited: 19 -
HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors.
Journal of immunology (Baltimore, Md. : 1950).
2006
Academic Article
GET IT
Times cited: 173 -
Protection of macaques from vaginal SHIV challenge by an orally delivered CCR5 inhibitor.
Nature medicine.
2005
Academic Article
GET IT
Times cited: 82 -
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion.
Nature.
2005
Academic Article
GET IT
Times cited: 270 -
The impact of envelope glycoprotein cleavage on the antigenicity, infectivity, and neutralization sensitivity of Env-pseudotyped human immunodeficiency virus type 1 particles.
Virology.
2005
Academic Article
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Times cited: 61 -
Recombinant gp120, antibodies to the V3 region of gp120, and neural progenitor cells.
The Journal of infectious diseases.
2005
Article
GET IT
Times cited: 1 -
V3: HIV's switch-hitter.
AIDS research and human retroviruses.
2005
Information Resource
GET IT
Times cited: 237 -
Effect of a CCR5 inhibitor on viral loads in macaques dual-infected with R5 and X4 primate immunodeficiency viruses.
Virology.
2004
Academic Article
GET IT
Times cited: 47 -
Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.
The Journal of experimental medicine.
2003
Academic Article
GET IT
Times cited: 142 -
Human T-cell leukemia virus type 1 envelope glycoprotein gp46 interacts with cell surface heparan sulfate proteoglycans.
Journal of virology.
2003
Academic Article
GET IT
Times cited: 88 -
Entry inhibitors SCH-C, RANTES, and T-20 block HIV type 1 replication in multiple cell types.
AIDS research and human retroviruses.
2003
Academic Article
GET IT
Times cited: 47 -
Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.
Nature medicine.
2003
Academic Article
GET IT
Times cited: 425 -
Human immunodeficiency virus type 1 attachment, coreceptor, and fusion inhibitors are active against both direct and trans infection of primary cells.
Journal of virology.
2003
Academic Article
GET IT
Times cited: 56 -
Occupancy and mechanism in antibody-mediated neutralization of animal viruses.
The Journal of general virology.
2002
Information Resource
GET IT
Times cited: 215 -
Mechanisms of virus neutralization by antibody.
Current topics in microbiology and immunology.
2001
Information Resource
GET IT
Times cited: 46 -
CD4-Chemokine receptor hybrids in human immunodeficiency virus type 1 infection.
Journal of virology.
1999
Academic Article
GET IT
Times cited: 14 - Mechanisms of enveloped virus entry into animal cells. Advanced drug delivery reviews. 1998 Academic Article GET IT
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Differential regulation of CXCR4 and CCR5 endocytosis.
Journal of cell science.
1998
Academic Article
GET IT
Times cited: 120 -
Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.
Virology.
1998
Academic Article
GET IT
Times cited: 67 -
Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity.
Journal of virology.
1998
Academic Article
GET IT
Times cited: 182 -
Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.
The Journal of cell biology.
1997
Academic Article
GET IT
Times cited: 341 -
Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein.
Journal of virology.
1997
Academic Article
GET IT
Times cited: 62 -
Inhibition of virus attachment to CD4+ target cells is a major mechanism of T cell line-adapted HIV-1 neutralization.
The Journal of experimental medicine.
1997
Academic Article
GET IT
Times cited: 110 -
Differential regulation of the antibody responses to Gag and Env proteins of human immunodeficiency virus type 1.
Journal of virology.
1997
Academic Article
GET IT
Times cited: 161 -
Altered CD4 interactions of HIV type 1 LAI variants selected for the capacity to induce membrane fusion in the presence of a monoclonal antibody to domain 2 of CD4.
AIDS research and human retroviruses.
1996
Academic Article
GET IT
Times cited: 6 -
Quantitative model of antibody- and soluble CD4-mediated neutralization of primary isolates and T-cell line-adapted strains of human immunodeficiency virus type 1.
Journal of virology.
1996
Academic Article
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Times cited: 73 -
Antibody neutralization of HIV-1.
Immunology today.
1996
Information Resource
GET IT
Times cited: 88 -
HIV. Cyclophilins unfold the Gag?.
Nature.
1993
Article
GET IT
Times cited: 13 -
An immune-selected point mutation in the transmembrane protein of human immunodeficiency virus type 1 (HXB2-Env:Ala 582(-->Thr)) decreases viral neutralization by monoclonal antibodies to the CD4-binding site.
Virology.
1993
Academic Article
GET IT
Times cited: 36 -
Soluble CD4 and CD4 immunoglobulin-selected HIV-1 variants: a phenotypic characterization.
AIDS research and human retroviruses.
1993
Academic Article
GET IT
Times cited: 20 -
Three-dimensional structure and antigenicity of transmembrane-protein peptides of the human immunodeficiency virus type 1. Effects of a neutralization-escape substitution.
FEBS letters.
1993
Academic Article
GET IT
Times cited: 4 -
A monoclonal antibody to CD4 domain 2 blocks soluble CD4-induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells.
Journal of virology.
1992
Academic Article
GET IT
Times cited: 127 -
Human and murine monoclonal antibodies directed against a conserved sequence from gp41 (aa583-599) of human immunodeficiency virus type 1.
Research in virology.
1992
Academic Article
GET IT
Times cited: 10 -
Thermodynamic and kinetic analysis of sCD4 binding to HIV-1 virions and of gp120 dissociation.
AIDS research and human retroviruses.
1992
Academic Article
GET IT
Times cited: 43 -
Kinetics of the HIV-CD4 interactions and virus-cell fusion.
AIDS (London, England).
1992
Editorial Article
GET IT
Times cited: 7 -
Rat monoclonal antibodies to nonoverlapping epitopes of human immunodeficiency virus type 1 gp120 block CD4 binding in vitro.
Virology.
1991
Academic Article
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Times cited: 42 -
A cluster of continuous antigenic structures in the transmembrane protein of HIV-1: individual patterns of reactivity in human sera.
Molecular immunology.
1991
Academic Article
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Times cited: 6 -
HIV-1 neutralization directed to epitopes other than linear V3 determinants.
AIDS (London, England).
1991
Information Resource
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Times cited: 14 -
Analysis of a highly immunodominant epitope in the human immunodeficiency virus type 1 transmembrane glycoprotein, gp41, defined by a human monoclonal antibody.
Journal of virology.
1990
Academic Article
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Times cited: 18 -
The site of an immune-selected point mutation in the transmembrane protein of human immunodeficiency virus type 1 does not constitute the neutralization epitope.
Journal of virology.
1990
Academic Article
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Times cited: 70 -
Antibodies to a putative HIV gp41 immunosuppressive peptide, pHIVIS (583-599), do not correlate significantly with outcome in HIV infection.
AIDS (London, England).
1990
Academic Article
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Times cited: 16 -
Cross-reactivity with SIVmac in east African HIV-1-positive sera: evidence against double infection with HIV-1 and a SIVmac/HIV-2-like virus.
Intervirology.
1990
Academic Article
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Times cited: 1 -
Differential IgG subclass responses to epitopes in transmembrane protein of HIV-1.
Viral immunology.
1990
Academic Article
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Times cited: 7 -
An aberrant subclass pattern of HIV-specific immunoglobulin G in sera from haemophiliacs.
AIDS (London, England).
1988
Academic Article
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Times cited: 4 -
Presence of antibodies to a putatively immunosuppressive part of human immunodeficiency virus (HIV) envelope glycoprotein gp41 is strongly associated with health among HIV-positive subjects.
Proceedings of the National Academy of Sciences of the United States of America.
1988
Academic Article
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Times cited: 107 -
Quantification of immunoglobulin on electrophoretic immunoblot strips as a tool for human immunodeficiency virus serodiagnosis.
Journal of clinical microbiology.
1988
Academic Article
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Times cited: 8 -
Specificities and sensitivities of three systems for determination of antibodies to human immunodeficiency virus by electrophoretic immunoblotting.
Journal of clinical microbiology.
1988
Academic Article
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Times cited: 10 -
Patterns of antibodies to human immunodeficiency virus proteins in different subclasses of IgG.
The Journal of infectious diseases.
1987
Academic Article
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Times cited: 24 -
Anti-STLV-IIImac reactivity in HIV seropositive individuals in Sweden.
Lancet (London, England).
1986
Article
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Times cited: 3