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- Author Correction: Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B. 2024
- Author Correction: Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies. 2022
- Corrigendum: Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease. 2016
- Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve immunotherapy.. 25. 2024
- cGAS meets its demise in the nucleus. 2024
- Pas de deux of NLRP3 and ASC with CD63 on mast cell granules. 2024
- Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells. 2024
- Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults. 2024
- IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development. 2024
- Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke. 2024
- Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19. 2023
- Control of nutrient uptake by IRF4 orchestrates innate immune memory.. 24. 2023
- Hallmarks of CD8+ T cell dysfunction are established within hours of tumor antigen encounter before cell division. 2023
- Apoptotic contraction drives target cell release by cytotoxic T cells. 2023
- Drivers of heterogeneity in synovial fibroblasts in rheumatoid arthritis. 2023
- Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies.. 24. 2023
- T cell egress via lymphatic vessels is tuned by antigen encounter and limits tumor control.. 24. 2023
- Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cells.. 24. 2022
- Learning from our differences. 2022
- NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia.. 23. 2022
- Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B. 2022
- Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies.. 23. 2022
- Caspase-11 interaction with NLRP3 potentiates the noncanonical activation of the NLRP3 inflammasome. 2022
- B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis.. 23. 2022
- Group 3 innate lymphoid cells produce the growth factor HB-EGF to protect the intestine from TNF-mediated inflammation.. 23. 2022
- Intravital three-photon microscopy allows visualization over the entire depth of mouse lymph nodes. 2022
- Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor families.. 23. 2021
- OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity. 2021
- Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity.. 22. 2021
- Regulatory T cells function in established systemic inflammation and reverse fatal autoimmunity.. 22. 2021
- Deconvoluting global cytokine signaling networks in natural killer cells.. 22. 2021
- TAP dysfunction in dendritic cells enables noncanonical cross-presentation for T cell priming.. 22. 2021
- Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.. 22. 2021
- Proinflammatory IgG Fc structures in patients with severe COVID-19.. 22. 2020
- Mapping systemic lupus erythematosus heterogeneity at the single-cell level.. 21. 2020
- Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy.. 21. 2020
- Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen.. 21. 2020
- Foxp3: a genetic foundation for regulatory T cell differentiation and function.. 21. 2020
- CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.. 21. 2020
- High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.. 21. 2019
- The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation.. 20. 2019
- PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance.. 20. 2019
- Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways.. 20. 2019
- Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.. 20. 2019
- CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment.. 20. 2019
- Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion.. 20. 2019
- A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.. 20. 2019
- IL-13 secreted by ILC2s promotes the self-renewal of intestinal stem cells through circular RNA circPan3.. 20. 2019
- Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function.. 20. 2019
- Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis.. 20. 2018
- The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types.. 19. 2018
- Regulation of age-associated B cells by IRF5 in systemic autoimmunity.. 19. 2018
- Type I interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation.. 18. 2017
- Post-translational control of T cell development by the ESCRT protein CHMP5.. 18. 2017
- Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract.. 17. 2016
- An essential role for the IL-2 receptor in Treg cell function.. 17. 2016
- Apoptosis in response to microbial infection induces autoreactive TH17 cells.. 17. 2016
- The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation.. 17. 2016
- Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.. 17. 2016
- Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease.. 17. 2016
- Control of T cell antigen reactivity via programmed TCR downregulation.. 17. 2016
- Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract. 17:1373-1380. 2016
- The transcription factor XBP1 is selectively required for eosinophil differentiation.. 16. 2015
- Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation.. 16. 2015
- The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor.. 16. 2015
- TET1 is a tumor suppressor of hematopoietic malignancy.. 16. 2015
- IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.. 16. 2015
- The RNA-binding protein HuR is essential for the B cell antibody response.. 16. 2015
- Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance.. 16. 2014
- A central role for Notch in effector CD8(+) T cell differentiation.. 15. 2014
- A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4.. 15. 2014
- Continuous requirement for the TCR in regulatory T cell function.. 15. 2014
- Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice.. 15. 2014
- Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells.. 15. 2014
- The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.. 14. 2013
- MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma.. 14. 2013
- Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways.. 14. 2013
- Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.. 14. 2013
- Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment.. 14. 2013
- Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms.. 14. 2013
- The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA.. 14. 2012
- The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response.. 13. 2012
- Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.. 13. 2012
- Transcription factor Foxp3 and its protein partners form a complex regulatory network.. 13. 2012
- OX40 signaling favors the induction of T(H)9 cells and airway inflammation.. 13. 2012
- Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.. 13. 2012
- B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen.. 13. 2011
- Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus.. 12. 2011
- The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells.. 12. 2011
- Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.. 12. 2011
- Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages.. 12. 2011
- Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk.. 12. 2011
- Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.. 12. 2010
- IL-35-mediated induction of a potent regulatory T cell population.. 11. 2010
- The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88.. 11. 2010
- Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II.. 11. 2010
- Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells.. 11. 2010
- Navigating the leukocyte signaling maze guided by Ariadne's thread.. 10. 2009
- Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.. 10. 2009
- Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells.. 10. 2009
- HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits.. 10. 2009
- Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils.. 10. 2009
- Intraclonal competition limits the fate determination of regulatory T cells in the thymus.. 10. 2009
- MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.. 10. 2009
- A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1.. 10. 2009
- T cell antigen receptor signaling and immunological synapse stability require myosin IIA.. 10. 2009
- SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway.. 9. 2008
- TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes.. 9. 2008
- Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis.. 9. 2008
- 'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages.. 9. 2007
- Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10.. 8. 2007
- Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR.. 8. 2007
- Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.. 8. 2007
- Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI.. 8. 2007
- Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.. 8. 2007
- Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice.. 8. 2006
- ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23.. 7. 2006
- Disruption of diacylglycerol metabolism impairs the induction of T cell anergy.. 7. 2006
- An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires.. 7. 2006
- MyD88-mediated stabilization of interferon-gamma-induced cytokine and chemokine mRNA.. 7. 2006
- Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells.. 7. 2006
- Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.. 6. 2005
- A function for interleukin 2 in Foxp3-expressing regulatory T cells.. 6. 2005
- Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells.. 6. 2005
- Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors.. 5. 2004
- Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone.. 5. 2004
- Two isoforms of otubain 1 regulate T cell anergy via GRAIL.. 5. 2003
- Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance.. 4. 2003
- Lymphotoxin pathway directs thymic Aire expression.. 4. 2003
- Enhanced T cell responses due to diacylglycerol kinase zeta deficiency.. 4. 2003
- Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.. 4. 2003
- Thymocyte expression of cathepsin L is essential for NKT cell development.. 3. 2002
- Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation.. 3. 2002
- Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo.. 3. 2001
- Development of chronic colitis is dependent on the cytokine MIF.. 2. 2001
- Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells.. 2. 2001
- CTLA-4 up-regulation plays a role in tolerance mediated by CD45.. 2. 2001
- BCL-6 regulates chemokine gene transcription in macrophages.. 1. 2000
- Circulating human B cells that express surrogate light chains and edited receptors.. 1. 2000
- Gene regulatory networks STARR-ing B cells.. 21. 2020
- Subverting misconceptions about radiation therapy.. 17. 2016
- Retraction: Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways.. 15. 2014
- Putting the brakes on innate immunity: a regulatory role for CD200?. 2. 2001
- Beta testing the monkey model. 2021
- DNA methylation secures CD4(+) and CD8(+) T cell lineage borders. 2015
- Dampening insulin signaling by an NLRP3 'meta-flammasome'. 2011
- Dual TCR T cells: gaining entry into the periphery. 2002
- Innate immunity--beginning to fulfill its promise? 2000
- Regulatory T cells: recommendations to simplify the nomenclature. 2013
- Lymphocyte signaling: a Tuscan affair. 2011
- Metchnikoff's Legacy in 2008. 2008
- Antigen receptor signaling: the Tuscan connection. 2007
- Antigen receptor signaling: the Tuscan chronicles. 2005
- Inhibitory receptors and ligands beyond PD-1, PD-L1 and CTLA-4: breakthroughs or backups. 2019
- Regulation of inflammation by microbiota interactions with the host. 2017
- Emerging concepts of epigenetic dysregulation in hematological malignancies. 2016
- Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis. 2016
- Commensal bacteria at the interface of host metabolism and the immune system. 2013
- From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines. 2012
- Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. 2011
- Sensing the outside world: TSLP regulates barrier immunity. 2010
- Cross-regulation of signaling by ITAM-associated receptors. 2009
- Adaptors as central mediators of signal transduction in immune cells. 2003
- Non-mutational neoantigens in disease. 2024
- A decade of checkpoint blockade immunotherapy in melanoma: understanding the molecular basis for immune sensitivity and resistance. 2022
- Immunogenic cell stress and death. 2022
- Interferon target-gene expression and epigenomic signatures in health and disease. 2019
- Foxp3 in control of the regulatory T cell lineage. 2007
- A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. 2005