Journal of virology

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Recombination between feline leukemia virus subgroup B or C and endogenous env elements alters the in vitro biological activities of the viruses. 1992
A human cytomegalovirus prefusion-like glycoprotein B subunit vaccine elicits humoral immunity similar to that of postfusion gB in mice. 2025
The pseudorabies virus UL13 protein kinase triggers phosphorylation of the RNA demethylase FTO, which is associated with FTO-dependent suppression of interferon-stimulated gene expression. 2025
Immune restoration by TIGIT blockade is insufficient to control chronic SIV infection. 2024
Reactivation of Epstein-Barr Virus from Latency Involves Increased RNA Polymerase Activity at CTCF Binding Sites on the Viral Genome.. 97. 2023
Novel Epitopes of the Influenza Virus N1 Neuraminidase Targeted by Human Monoclonal Antibodies.. 96. 2022
Human Anti-neuraminidase Antibodies Reduce Airborne Transmission of Clinical Influenza Virus Isolates in the Guinea Pig Model.. 96. 2021
The glycan hole area of HIV-1 envelope trimers contributes prominently to the induction of autologous neutralization. 2021
The NF-κB transcriptional footprint is essential for SARS-CoV-2 replication. 2021
Antibodies from Rabbits Immunized with HIV-1 Clade B SOSIP Trimers Can Neutralize Multiple Clade B Viruses by Destabilizing the Envelope Glycoprotein.. 95. 2021
African-Lineage Zika Virus Replication Dynamics and Maternal-Fetal Interface Infection in Pregnant Rhesus Macaques.. 95. 2021
Intranasal Nanoparticle Vaccination Elicits a Persistent, Polyfunctional CD4 T Cell Response in the Murine Lung Specific for a Highly Conserved Influenza Virus Antigen That Is Sufficient To Mediate Protection from Influenza Virus Challenge.. 95. 2021
Selective BCL-X_L Antagonists Eliminate Infected Cells from a Primary-Cell Model of HIV Latency but Not from Ex Vivo Reservoirs.. 95. 2021
Rapid evolution of enhanced Zika virus virulence during direct vertebrate transmission chains. 2021
Zika virus infection induced apoptosis by modulating the recruitment and activation of pro-apoptotic protein Bax. 2021
Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers.. 94. 2020
Characterization of Novel Cross-Reactive Influenza B Virus Hemagglutinin Head Specific Antibodies That Lack Hemagglutination Inhibition Activity.. 94. 2020
Drug Resistance Mutation Frequency of Single-Genome Amplification-Derived HIV-1 Polymerase Genomes in the Cerebrospinal Fluid and Plasma of HIV-1-Infected Individuals under Nonsuppressive Therapy.. 94. 2020
Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands.. 94. 2020
Seminal Plasma-Derived Extracellular-Vesicle Fractions from HIV-Infected Men Exhibit Unique MicroRNA Signatures and Induce a Proinflammatory Response in Cells Isolated from the Female Reproductive Tract.. 94. 2020
Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes.. 94. 2020
Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins.. 94. 2020
Integrated Assessment of Viral Transcription, Antigen Presentation, and CD8⁺ T Cell Function Reveals Multiple Limitations of Class I-Selective Histone Deacetylase Inhibitors during HIV-1 Latency Reversal.. 94. 2020
Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits.. 94. 2020
Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin.. 94. 2020
Kaposi's Sarcoma-Associated Herpesvirus LANA Modulates the Stability of the E3 Ubiquitin Ligase RLIM.. 94. 2020
SOS and IP Modifications Predominantly Affect the Yield but Not Other Properties of SOSIP.664 HIV-1 Env Glycoprotein Trimers.. 94. 2019
Monoclonal Antibody Responses after Recombinant Hemagglutinin Vaccine versus Subunit Inactivated Influenza Virus Vaccine: a Comparative Study.. 93. 2019
Antibody Responses Elicited by Immunization with BG505 Trimer Immune Complexes.. 93. 2019
Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells.. 93. 2019
Characterization of Novel Splice Variants of Zinc Finger Antiviral Protein (ZAP).. 93. 2019
Simian-Human Immunodeficiency Virus SHIV.CH505-Infected Infant and Adult Rhesus Macaques Exhibit Similar Env-Specific Antibody Kinetics, despite Distinct T-Follicular Helper and Germinal Center B Cell Landscapes.. 93. 2019
Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes.. 93. 2019
Hemagglutinin Stalk-Reactive Antibodies Interfere with Influenza Virus Neuraminidase Activity by Steric Hindrance.. 93. 2019
Genotypic and Mechanistic Characterization of Subtype-Specific HIV Adaptation to Host Cellular Immunity.. 93. 2018
Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge.. 92. 2018
Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro.. 92. 2018
Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20.. 92. 2018
Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques.. 92. 2018
Immunogenicity in Rabbits of HIV-1 SOSIP Trimers from Clades A, B, and C, Given Individually, Sequentially, or in Combination.. 92. 2018
Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Clade B Clinical Isolates Produced in Peripheral Blood Mononuclear Cells.. 92. 2018
High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers.. 91. 2017
Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope.. 91. 2017
Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers.. 91. 2017
Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression.. 91. 2017
Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes.. 91. 2017
Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment.. 91. 2017
Convallatoxin-Induced Reduction of Methionine Import Effectively Inhibits Human Cytomegalovirus Infection and Replication.. 90. 2016
HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein Spike.. 90. 2016
Varicella-Zoster Virus Downregulates Programmed Death Ligand 1 and Major Histocompatibility Complex Class I in Human Brain Vascular Adventitial Fibroblasts, Perineurial Cells, and Lung Fibroblasts.. 90. 2016
Sindbis Virus Can Exploit a Host Antiviral Protein To Evade Immune Surveillance.. 90. 2016
B Cell Responses during Secondary Dengue Virus Infection Are Dominated by Highly Cross-Reactive, Memory-Derived Plasmablasts.. 90. 2016
Respiratory Syncytial Virus (RSV) Pulmonary Infection in Humanized Mice Induces Human Anti-RSV Immune Responses and Pathology.. 90. 2016
Chaperone-Assisted Protein Folding Is Critical for Yellow Fever Virus NS3/4A Cleavage and Replication.. 90. 2016
Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology.. 90. 2015
Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.. 89. 2015
Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity.. 89. 2015
Simian Varicella Virus Is Present in Macrophages, Dendritic Cells, and T Cells in Lymph Nodes of Rhesus Macaques after Experimental Reactivation.. 89. 2015
Distinct Immune Responses in Resistant and Susceptible Strains of Mice during Neurovirulent Alphavirus Encephalomyelitis.. 89. 2015
What Do Chaotrope-Based Avidity Assays for Antibodies to HIV-1 Envelope Glycoproteins Measure?. 89. 2015
Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression.. 89. 2015
A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.. 89. 2015
High preexisting serological antibody levels correlate with diversification of the influenza vaccine response.. 89. 2015
Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus.. 88. 2014
Seed sequence-matched controls reveal limitations of small interfering RNA knockdown in functional and structural studies of hepatitis C virus NS5A-MOBKL1B interaction.. 88. 2014
HIV-1 Vpu antagonism of tetherin inhibits antibody-dependent cellular cytotoxic responses by natural killer cells.. 88. 2014
Divergent H7 immunogens offer protection from H7N9 virus challenge.. 88. 2014
Utility of humanized BLT mice for analysis of dengue virus infection and antiviral drug testing.. 88. 2013
LINE-1 retrotransposable element DNA accumulates in HIV-1-infected cells.. 87. 2013
The product of Kaposi's sarcoma-associated herpesvirus immediate early gene K4.2 regulates immunoglobulin secretion and calcium homeostasis by interacting with and inhibiting pERP1.. 87. 2013
Hemagglutinin stalk-based universal vaccine constructs protect against group 2 influenza A viruses.. 87. 2013
Influences on trimerization and aggregation of soluble, cleaved HIV-1 SOSIP envelope glycoprotein.. 87. 2013
Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers.. 87. 2013
High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration.. 87. 2013
Different requirements for scavenger receptor class B type I in hepatitis C virus cell-free versus cell-to-cell transmission.. 87. 2013
Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype.. 87. 2013
Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design.. 87. 2013
Identification of a pegivirus (GB virus-like virus) that infects horses.. 87. 2013
Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses.. 87. 2013
Use of G-protein-coupled and -uncoupled CCR5 receptors by CCR5 inhibitor-resistant and -sensitive human immunodeficiency virus type 1 variants.. 87. 2013
Genetic and functional characterization of the N-terminal region of the hepatitis C virus NS2 protein.. 87. 2013
The frequency of CD127(+) hepatitis C virus (HCV)-specific T cells but not the expression of exhaustion markers predicts the outcome of acute HCV infection.. 87. 2013
Most influenza a virions fail to express at least one essential viral protein.. 87. 2013
Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5.. 87. 2012
Intersubtype differences in the effect of a rare p24 gag mutation on HIV-1 replicative fitness.. 86. 2012
Flavivirus replication complex assembly revealed by DNAJC14 functional mapping.. 86. 2012
Glycan-dependent immunogenicity of recombinant soluble trimeric hemagglutinin.. 86. 2012
Broadly neutralizing immune responses against hepatitis C virus induced by vectored measles viruses and a recombinant envelope protein booster.. 86. 2012
Serology-enabled discovery of genetically diverse hepaciviruses in a new host.. 86. 2012
C7L family of poxvirus host range genes inhibits antiviral activities induced by type I interferons and interferon regulatory factor 1.. 86. 2012
Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans.. 86. 2012
Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.. 86. 2011
Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies.. 85. 2011
HIV-1 infection abrogates CD8+ T cell mitogen-activated protein kinase signaling responses.. 85. 2011
Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.. 85. 2011
Resistance of human immunodeficiency virus type 1 to a third-generation fusion inhibitor requires multiple mutations in gp41 and is accompanied by a dramatic loss of gp41 function.. 85. 2011
Inhibition of p53 by adenovirus type 12 E1B-55K deregulates cell cycle control and sensitizes tumor cells to genotoxic agents.. 85. 2011
Multiple CCR5 conformations on the cell surface are used differentially by human immunodeficiency viruses resistant or sensitive to CCR5 inhibitors.. 85. 2011
Hepatitis C virus co-opts Ras-GTPase-activating protein-binding protein 1 for its genome replication.. 85. 2011
Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection.. 85. 2011
Transgenic expression of polyomavirus middle T antigen in the mouse prostate gives rise to carcinoma.. 85. 2011
Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection.. 85. 2010
Molecular characterization of in vivo adjuvant activity in ferrets vaccinated against influenza virus.. 84. 2010
Splicing diversity of the human OCLN gene and its biological significance for hepatitis C virus entry.. 84. 2010
Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: role for G3BP1 and G3BP2 in virus replication.. 84. 2010
Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization.. 84. 2010
Identification of a dominant negative inhibitor of human zinc finger antiviral protein reveals a functional endogenous pool and critical homotypic interactions.. 84. 2010
Caspase 9 is essential for herpes simplex virus type 2-induced apoptosis in T cells.. 84. 2010
Role of scavenger receptor class B type I in hepatitis C virus entry: kinetics and molecular determinants.. 84. 2010
Genetic analysis of the carboxy-terminal region of the hepatitis C virus core protein.. 84. 2009
Determinants of the hepatitis C virus nonstructural protein 2 protease domain required for production of infectious virus.. 83. 2009
Artificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor.. 83. 2009
Kinetic dependence of paramyxovirus entry inhibition.. 83. 2009
Mutations in hepatitis C virus E2 located outside the CD81 binding sites lead to escape from broadly neutralizing antibodies but compromise virus infectivity.. 83. 2009
Cell-specific transduction of Prdm1-expressing lineages mediated by a receptor for avian leukosis virus subgroup B.. 83. 2009
Role of defective Oct-2 and OCA-B expression in immunoglobulin production and Kaposi's sarcoma-associated herpesvirus lytic reactivation in primary effusion lymphoma.. 83. 2009
Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling.. 83. 2009
Internal initiation stimulates production of p8 minicore, a member of a newly discovered family of hepatitis C virus core protein isoforms.. 83. 2009
Cell type-specific induction and inhibition of apoptosis by Herpes Simplex virus type 2 ICP10.. 83. 2008
Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point.. 83. 2008
Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia.. 82. 2008
A dynamic view of hepatitis C virus replication complexes.. 82. 2008
Vaccinia virus subverts a mitochondrial antiviral signaling protein-dependent innate immune response in keratinocytes through its double-stranded RNA binding protein, E3.. 82. 2008
Gene expression analysis of host innate immune responses during Lethal H5N1 infection in ferrets.. 82. 2008
Selection of T1249-resistant human immunodeficiency virus type 1 variants.. 82. 2008
Ataxia telangiectasia-mutated damage-signaling kinase- and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in Simian virus 40-infected primate cells.. 82. 2008
Conferral of enhanced natural killer cell function by KIR3DS1 in early human immunodeficiency virus type 1 infection.. 82. 2008
Transdominant inhibition of bovine viral diarrhea virus entry.. 82. 2007
Bovine viral diarrhea virus core is an intrinsically disordered protein that binds RNA.. 82. 2007
Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein.. 82. 2007
3' RNA elements in hepatitis C virus replication: kissing partners and long poly(U).. 82. 2007
Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection.. 82. 2007
Protective immunity to pseudomonas aeruginosa induced with a capsid-modified adenovirus expressing P. aeruginosa OprF.. 81. 2007
Identification of novel antipoxviral agents: mitoxantrone inhibits vaccinia virus replication by blocking virion assembly.. 81. 2007
Alanine scanning of the hepatitis C virus core protein reveals numerous residues essential for production of infectious virus.. 81. 2007
The C terminus of hepatitis C virus NS4A encodes an electrostatic switch that regulates NS5A hyperphosphorylation and viral replication.. 81. 2007
Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus.. 81. 2007
Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome.. 81. 2007
High-avidity monoclonal antibodies against the human scavenger class B type I receptor efficiently block hepatitis C virus infection in the presence of high-density lipoprotein.. 81. 2007
Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection.. 81. 2007
Participation of rab5, an early endosome protein, in hepatitis C virus RNA replication machinery.. 81. 2007
Superinfection exclusion in cells infected with hepatitis C virus.. 81. 2007
Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator.. 81. 2007
Mathematical modeling of subgenomic hepatitis C virus replication in Huh-7 cells.. 81. 2006
Neutralized adenovirus-immune complexes can mediate effective gene transfer via an Fc receptor-dependent infection pathway.. 80. 2006
Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells.. 80. 2006
Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa.. 80. 2006
Crystal structure of the moloney murine leukemia virus RNase H domain.. 80. 2006
Diverse CD81 proteins support hepatitis C virus infection.. 80. 2006
A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes.. 80. 2006
The NS5A protein of bovine viral diarrhea virus contains an essential zinc-binding site similar to that of the hepatitis C virus NS5A protein.. 80. 2006
Epitopes expressed in different adenovirus capsid proteins induce different levels of epitope-specific immunity.. 80. 2006
Paramyxovirus receptor-binding molecules: engagement of one site on the hemagglutinin-neuraminidase protein modulates activity at the second site.. 80. 2006
Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry.. 80. 2006
Liver-directed gamma interferon gene delivery in chronic hepatitis C.. 79. 2005
Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation.. 79. 2005
Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.. 79. 2005
Activation of CD21 and CD23 gene expression by Kaposi's sarcoma-associated herpesvirus RTA.. 79. 2005
Requirements at the 3' end of the sindbis virus genome for efficient synthesis of minus-strand RNA.. 79. 2005
Dual mechanisms of pestiviral superinfection exclusion at entry and RNA replication.. 79. 2005
Recombinant mouse hepatitis virus strain A59 from cloned, full-length cDNA replicates to high titers in vitro and is fully pathogenic in vivo.. 79. 2005
Influence of the human parainfluenza virus 3 attachment protein's neuraminidase activity on its capacity to activate the fusion protein.. 79. 2005
Distinct subsets of primary effusion lymphoma can be identified based on their cellular gene expression profile and viral association.. 79. 2005
Inhibition of parainfluenza virus type 3 and Newcastle disease virus hemagglutinin-neuraminidase receptor binding: effect of receptor avidity and steric hindrance at the inhibitor binding sites.. 78. 2004
Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor.. 78. 2004
Genetic interactions between hepatitis C virus replicons.. 78. 2004
Hepatitis C virus core protein associates with detergent-resistant membranes distinct from classical plasma membrane rafts.. 78. 2004
An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication.. 78. 2004
Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1.. 78. 2004
Cytoplasmic dynein mediates adenovirus binding to microtubules.. 78. 2004
Long-term persistence of infection in chimpanzees inoculated with an infectious hepatitis C virus clone is associated with a decrease in the viral amino acid substitution rate and low levels of heterogeneity.. 78. 2004
R5 human immunodeficiency virus type 1 (HIV-1) replicates more efficiently in primary CD4+ T-cell cultures than X4 HIV-1.. 78. 2004
Characterization of the mouse adeno-associated virus AAVS1 ortholog.. 78. 2004
Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells.. 78. 2004
Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner.. 78. 2004
PKR-dependent and -independent mechanisms are involved in translational shutoff during Sindbis virus infection.. 78. 2004
Characterization of infectious retroviral pseudotype particles bearing hepatitis C virus glycoproteins.. 78. 2004
Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes.. 78. 2004
CKII site in Epstein-Barr virus nuclear protein 2 controls binding to hSNF5/Ini1 and is important for growth transformation.. 78. 2004
Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus.. 78. 2004
Coronavirus neurovirulence correlates with the ability of the virus to induce proinflammatory cytokine signals from astrocytes and microglia.. 78. 2004
Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load.. 78. 2004
Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responses.. 78. 2004
Uncleaved NS2-3 is required for production of infectious bovine viral diarrhea virus.. 78. 2004
A cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replication.. 78. 2004
CD81 is required for hepatitis C virus glycoprotein-mediated viral infection.. 78. 2004
Selection of functional 5' cis-acting elements promoting efficient sindbis virus genome replication.. 78. 2004
Association of adenovirus with the microtubule organizing center.. 77. 2003
Expression of the zinc-finger antiviral protein inhibits alphavirus replication.. 77. 2003
Human T-cell leukemia virus type 1 envelope glycoprotein gp46 interacts with cell surface heparan sulfate proteoglycans.. 77. 2003
Development and application of a reverse genetics system for Japanese encephalitis virus.. 77. 2003
Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication.. 77. 2003
Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR.. 77. 2003
Kinetics of CD4+ and CD8+ memory T-cell responses during hepatitis C virus rechallenge of previously recovered chimpanzees.. 77. 2003
Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture.. 77. 2003
Triggering of human parainfluenza virus 3 fusion protein (F) by the hemagglutinin-neuraminidase (HN) protein: an HN mutation diminishes the rate of F activation and fusion.. 77. 2003
Hepatitis C virus RNA synthesis in a cell-free system isolated from replicon-containing hepatoma cells.. 77. 2003
Human immunodeficiency virus type 1 attachment, coreceptor, and fusion inhibitors are active against both direct and trans infection of primary cells.. 77. 2003
Identification of small molecule compounds that selectively inhibit varicella-zoster virus replication.. 77. 2003
Mutations in human parainfluenza virus type 3 hemagglutinin-neuraminidase causing increased receptor binding activity and resistance to the transition state sialic acid analog 4-GU-DANA (Zanamivir).. 77. 2003
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor has broad signaling effects in primary effusion lymphoma cells.. 77. 2003
A cis-acting element that directs circular adeno-associated virus replication and packaging.. 76. 2002
Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication.. 76. 2002
Tissue-specific transcriptional targeting of a replication-competent retroviral vector.. 76. 2002
Roles of nonstructural protein nsP2 and Alpha/Beta interferons in determining the outcome of Sindbis virus infection.. 76. 2002
Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.. 76. 2002
The Epstein-Barr virus SM protein is functionally similar to ICP27 from herpes simplex virus in viral infections.. 76. 2002
Inhibition of chemokine expression by adenovirus early region three (E3) genes.. 76. 2002
Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein.. 76. 2002
Characterization of vesicular stomatitis virus recombinants that express and incorporate high levels of hepatitis C virus glycoproteins.. 76. 2002
Previously infected and recovered chimpanzees exhibit rapid responses that control hepatitis C virus replication upon rechallenge.. 76. 2002
The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.. 76. 2002
An NF-kappa B-dependent survival pathway protects against cell death induced by TVB receptors for avian leukosis viruses.. 76. 2002
Molecular and immunological significance of chimpanzee major histocompatibility complex haplotypes for hepatitis C virus immune response and vaccination studies.. 76. 2002
Mutations in the yellow fever virus nonstructural protein NS2A selectively block production of infectious particles.. 76. 2002
Transcriptional downregulation of ORF50/Rta by methotrexate inhibits the switch of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 from latency to lytic replication.. 76. 2002
Apical budding of a recombinant influenza A virus expressing a hemagglutinin protein with a basolateral localization signal.. 76. 2002
Enhancing the proteolytic maturation of human immunodeficiency virus type 1 envelope glycoproteins.. 76. 2002
Isolation and characterization of noncytopathic pestivirus mutants reveals a role for nonstructural protein NS4B in viral cytopathogenicity.. 75. 2001
Development of an avian leukosis-sarcoma virus subgroup A pseudotyped lentiviral vector.. 75. 2001
A single amino acid alteration in the human parainfluenza virus type 3 hemagglutinin-neuraminidase glycoprotein confers resistance to the inhibitory effects of zanamivir on receptor binding and neuraminidase activity.. 75. 2001
Efficient translation initiation is required for replication of bovine viral diarrhea virus subgenomic replicons.. 75. 2001
Importance of the N terminus of rous sarcoma virus protease for structure and enzymatic function.. 75. 2001
Kaposi's sarcoma-associated herpesvirus can productively infect primary human keratinocytes and alter their growth properties.. 75. 2001
Murine coronavirus spike protein determines the ability of the virus to replicate in the liver and cause hepatitis.. 75. 2001
Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein.. 75. 2001
Rapid assessment of adenovirus serum neutralizing antibody titer based on quantitative, morphometric evaluation of capsid binding and intracellular trafficking: population analysis of adenovirus capsid association with cells is predictive of adenovirus infectivity.. 75. 2001
Demyelination determinants map to the spike glycoprotein gene of coronavirus mouse hepatitis virus.. 74. 2000
Variable-loop-deleted variants of the human immunodeficiency virus type 1 envelope glycoprotein can be stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits.. 74. 2000
Productive replication of human adenoviruses in mouse epidermal cells.. 74. 2000
A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure.. 74. 2000
Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domains.. 74. 2000
Induction of endogenous genes following infection of human endothelial cells with an E1(-) E4(+) adenovirus gene transfer vector.. 73. 1999
CD4-Chemokine receptor hybrids in human immunodeficiency virus type 1 infection.. 73. 1999
Pathogenesis of chimeric MHV4/MHV-A59 recombinant viruses: the murine coronavirus spike protein is a major determinant of neurovirulence.. 73. 1999
Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs.. 73. 1999
Expression and use of human immunodeficiency virus type 1 coreceptors by human alveolar macrophages.. 73. 1999
Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors.. 73. 1999
Early region 1 transforming functions are dispensable for mammary tumorigenesis by human adenovirus type 9.. 73. 1999
Targeted recombination within the spike gene of murine coronavirus mouse hepatitis virus-A59: Q159 is a determinant of hepatotropism.. 72. 1998
Role of variable regions A and B in receptor binding domain of amphotropic murine leukemia virus envelope protein.. 72. 1998
Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection.. 72. 1998
Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity.. 72. 1998
Alanine substitutions of polar and nonpolar residues in the amino-terminal domain of CCR5 differently impair entry of macrophage- and dualtropic isolates of human immunodeficiency virus type 1.. 72. 1998
Mtv-1 superantigen trafficks independently of major histocompatibility complex class II directly to the B-cell surface by the exocytic pathway.. 72. 1998
Genetic mapping of the cloned subgroup A avian sarcoma and leukosis virus receptor gene to the TVA locus.. 72. 1998
Structure-function analysis of the triphosphatase component of vaccinia virus mRNA capping enzyme.. 71. 1997
Identification of envelope protein residues required for the expanded host range of 10A1 murine leukemia virus.. 71. 1997
Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein.. 71. 1997
Genetic determinant of rapid-onset B-cell lymphoma by avian leukosis virus.. 71. 1997
Minimal truncation of the c-myb gene product in rapid-onset B-cell lymphoma.. 71. 1997
Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene.. 71. 1997
Differential regulation of the antibody responses to Gag and Env proteins of human immunodeficiency virus type 1.. 71. 1997
Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation.. 71. 1997
Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ.. 71. 1997
Kaposi's sarcoma-associated herpesvirus contains G protein-coupled receptor and cyclin D homologs which are expressed in Kaposi's sarcoma and malignant lymphoma.. 70. 1996
Constitutive retinoid receptors expressed from adenovirus vectors that specifically activate chromosomal target genes required for differentiation of promyelocytic leukemia and teratocarcinoma cells.. 70. 1996
Quantitative model of antibody- and soluble CD4-mediated neutralization of primary isolates and T-cell line-adapted strains of human immunodeficiency virus type 1.. 70. 1996
Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection.. 70. 1996
Primary characterization of a herpesvirus agent associated with Kaposi's sarcomae.. 70. 1996
Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes.. 70. 1996
The D1 and D12 subunits are both essential for the transcription termination factor activity of vaccinia virus capping enzyme.. 69. 1995
A point mutation in the env gene of a murine leukemia virus induces syncytium formation and neurologic disease.. 68. 1994
The receptor for the subgroup A avian leukosis-sarcoma viruses binds to subgroup A but not to subgroup C envelope glycoprotein.. 68. 1994
Phosphatidylcholine hydrolysis activates NF-kappa B and increases human immunodeficiency virus replication in human monocytes and T lymphocytes.. 67. 1993
Intracerebral hemorrhages and syncytium formation induced by endothelial cell infection with a murine leukemia virus.. 67. 1993
Isolation of a chicken gene that confers susceptibility to infection by subgroup A avian leukosis and sarcoma viruses.. 67. 1993
Fv-1 restriction and its effects on murine leukemia virus integration in vivo and in vitro.. 66. 1992
A monoclonal antibody to CD4 domain 2 blocks soluble CD4-induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells.. 66. 1992
Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae.. 66. 1992
NF-IL6, a member of the C/EBP family, regulates E1A-responsive promoters in the absence of E1A.. 66. 1992
Woodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host.. 65. 1991
Adenovirus E1A and E1B genes are regulated posttranscriptionally in human lymphoid cells.. 64. 1990
Effects of insertional and point mutations on the functions of the duck hepatitis B virus polymerase.. 64. 1990
Moloney murine leukemia virus integration protein produced in yeast binds specifically to viral att sites.. 64. 1990
Analysis of a highly immunodominant epitope in the human immunodeficiency virus type 1 transmembrane glycoprotein, gp41, defined by a human monoclonal antibody.. 64. 1990
The site of an immune-selected point mutation in the transmembrane protein of human immunodeficiency virus type 1 does not constitute the neutralization epitope.. 64. 1990
Passive immunity to fatal reovirus serotype 3-induced meningoencephalitis mediated by both secretory and transplacental factors in neonatal mice.. 64. 1990
Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions.. 63. 1989
Nucleotide sequence and distinctive characteristics of the env gene of endogenous feline leukemia provirus.. 63. 1989
Mapping of RNA- temperature-sensitive mutants of Sindbis virus: complementation group F mutants have lesions in nsP4.. 63. 1989
A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent manner.. 63. 1989
Latent herpes simplex virus type 1 transcription in human trigeminal ganglia.. 62. 1988
Model for studying virus attachment: identification and quantitation of Epstein-Barr virus-binding cells by using biotinylated virus in flow cytometry.. 62. 1988
Latent herpes simplex virus type 1 transcripts in peripheral and central nervous system tissues of mice map to similar regions of the viral genome.. 62. 1988
Expression of the precore region of an avian hepatitis B virus is not required for viral replication.. 61. 1987
In vitro recombinants of ground squirrel and woodchuck hepatitis viral DNAs produce infectious virus in squirrels.. 61. 1987
An aberrant avian leukosis virus provirus inserted downstream from the chicken c-myc coding sequence in a bursal lymphoma results from intrachromosomal recombination between two proviruses and deletion of cellular DNA.. 61. 1987
Retroviral DNA integrated during infection by an integration-deficient mutant of murine leukemia virus is oligomeric.. 61. 1987
Productive infection of cultured human lymphoid cells by adenovirus.. 61. 1987
The preS1 protein of hepatitis B virus is acylated at its amino terminus with myristic acid.. 61. 1987
5'-terminal sequences influence the segregation of ground squirrel hepatitis virus RNAs into polyribosomes and viral core particles.. 61. 1987
Antibodies to pre-S and X determinants arise during natural infection with ground squirrel hepatitis virus.. 60. 1986
Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions.. 56. 1985
Nucleotide sequence of an infectious molecularly cloned genome of ground squirrel hepatitis virus.. 51. 1984
Persistence of mouse hepatitis virus A59 RNA in a slow virus demyelinating infection in mice as detected by in situ hybridization.. 51. 1984
Phosphorylation of the ribosomal protein S6 is elevated in cells transformed by a variety of tumor viruses.. 50. 1984
Transcription of the hepatitis B surface antigen gene in cultured murine cells initiates within the presurface region.. 50. 1984
Closed circular viral DNA and asymmetrical heterogeneous forms in livers from animals infected with ground squirrel hepatitis virus.. 48. 1983
Nucleotide sequencing of an apparent proviral copy of env mRNA defines determinants of expression of the mouse mammary tumor virus env gene.. 47. 1983
Biological characterization of acute infection with ground squirrel hepatitis virus.. 44. 1982
Virion DNA of ground squirrel hepatitis virus: structural analysis and molecular cloning.. 44. 1982
Structure of a replication intermediate in the synthesis of Rous sarcoma virus DNA in vivo.. 42. 1982
Nucleotide sequence of the 5' noncoding region and part of the gag gene of Rous sarcoma virus.. 41. 1982
The leader sequence of the subgenomic mRNA's of Rous sarcoma virus is approximately 390 nucleotides.. 41. 1982
Dexamethasone induction of the intracellular RNAs of mouse mammary tumor virus.. 40. 1981
Proposal for naming host cell-derived inserts in retrovirus genomes.. 40. 1981
Purification and translation of murine mammary tumor virus mRNA's.. 39. 1981
Synthesis of plus strands of retroviral DNA in cells infected with avian sarcoma virus and mouse mammary tumor virus.. 37. 1981
Molecular cloning and characterization of avian sarcoma virus circular DNA molecules.. 36. 1980
Proviruses of mouse mammary tumor virus in normal and neoplastic tissues from GR and C3Hf mouse strains.. 35. 1980
Organization of mouse mammary tumor virus-specific DNA endogenous to BALB/c mice.. 32. 1979
Structural analysis of the intracellular RNAs of murine mammary tumor virus.. 30. 1979
env Gene of chicken RNA tumor viruses: extent of conservation in cellular and viral genomes.. 27. 1978
Virus-specific DNA in the cytoplasm of avian sarcoma virus-infected cells is a precursor to covalently closed circular viral DNA in the nucleus.. 25. 1978
Purification of DNA complementary to the env gene of avian sarcoma virus and analysis of relationships among the env genes of avian leukosis-sarcoma viruses.. 21. 1977
RNA complementary to the genome of RNA tumor viruses in virions and virus-producing cells.. 20. 1976
Unintegrated viral DNA is synthesized in the cytoplasm of avian sarcoma virus-transformed duck cells by viral DNA polymerase.. 18. 1976
Use of alkaline sucrose gradients in a zonal rotor to detect integrated and unintegrated avian sarcoma virus-specific DNA in cells.. 18. 1976
Use of DNA-DNA annealing to detect new virus-specific DNA sequences in chicken embryo fibroblasts after infection by avian sarcoma virus.. 14. 1974
Retraction. Moloney murine leukemia virus integration protein produced in yeast binds specifically to viral att sites.. 65. 1991
COVID-19 Vaccines: "Warp Speed" Needs Mind Melds, Not Warped Minds. 2020

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