Cell reports
Journal
Overview
publication venue for
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Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination.
2021
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Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans.
2019
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CCR2+ monocytes replenish border-associated macrophages in the diseased mouse brain..
43.
2024
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IQGAP1 and NWASP promote human cancer cell dissemination and metastasis by regulating β1-integrin via FAK and MRTF/SRF..
43.
2024
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Peroxisome deficiency underlies failures in hepatic immune cell development and antigen presentation in a severe Zellweger disease model..
43.
2024
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An axon-T cell feedback loop enhances inflammation and axon degeneration..
43.
2024
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CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis..
43.
2023
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Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms..
43.
2023
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Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk..
43.
2023
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Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy..
42.
2023
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Epinephrine inhibits PI3Kα via the Hippo kinases..
42.
2023
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Cerebellar contribution to autism-relevant behaviors in fragile X syndrome models..
42.
2023
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KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance..
42.
2023
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Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer..
42.
2023
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Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine..
42.
2023
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Single-nuclei multiomic analyses identify human cardiac lymphatic endothelial cells associated with coronary arteries in the epicardium..
42.
2023
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Cerebral electrometabolic coupling in disordered and normal states of consciousness..
42.
2023
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Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells..
42.
2023
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Glial progenitor heterogeneity and key regulators revealed by single-cell RNA sequencing provide insight to regeneration in spinal cord injury..
42.
2023
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Circadian protein TIMELESS regulates synaptic function and memory by modulating cAMP signaling..
42.
2023
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Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations..
42.
2023
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MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4γ-dependent transcription of CES enzymes..
42.
2023
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Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma..
42.
2023
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Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes..
42.
2023
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Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly.
42.
2023
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A role of cytoplasmic p53 in the regulation of metabolism shown by bat-mimicking p53 NLS mutant mice..
42.
2022
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Genomic heterogeneity as a barrier to precision oncology in urothelial cancer..
41.
2022
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AKTs do not translocate to the nucleus upon stimulation but AKT3 can constitutively signal from the nuclear envelope..
41.
2022
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Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning..
41.
2022
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Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity..
41.
2022
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Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease..
41.
2022
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POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells..
41.
2022
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Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis..
41.
2022
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Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis..
41.
2022
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A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation..
40.
2022
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Dietary-protein sources modulate host susceptibility to Clostridioides difficile infection through the gut microbiota..
40.
2022
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Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice..
40.
2022
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Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers..
40.
2022
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Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneity..
40.
2022
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Prenatal environmental stressors impair postnatal microglia function and adult behavior in males..
40.
2022
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Alphaherpesvirus US3 protein-mediated inhibition of the m6A mRNA methyltransferase complex..
40.
2022
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Cooperative action of gut-microbiota-accessible carbohydrates improves host metabolic function..
40.
2022
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Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal β cells..
40.
2022
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Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response..
40.
2022
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Flattening of circadian glucocorticoid oscillations drives acute hyperinsulinemia and adipocyte hypertrophy..
39.
2022
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A diminished immune response underlies age-related SARS-CoV-2 pathologies..
39.
2022
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Broadly recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA alleles..
39.
2022
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DDX41 is required for cGAS-STING activation against DNA virus infection..
39.
2022
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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC..
39.
2022
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The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62..
39.
2022
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Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression..
39.
2022
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Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex..
39.
2022
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Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins..
39.
2022
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Global evolution of the tumor microenvironment associated with progression from preinvasive invasive to invasive human lung adenocarcinoma..
39.
2022
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The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes..
38.
2022
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Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy..
38.
2022
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Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells..
38.
2022
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Regulation of the BCR signalosome by the class II peptide editor, H2-M, affects the development and repertoire of innate-like B cells..
38.
2022
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Kaposi's sarcoma herpesvirus activates the hypoxia response to usurp HIF2α-dependent translation initiation for replication and oncogenesis..
37.
2021
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Pan-cancer analysis reveals molecular patterns associated with age..
37.
2021
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Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation..
37.
2021
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ILC3s control airway inflammation by limiting T cell responses to allergens and microbes..
37.
2021
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Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases..
37.
2021
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MicroRNA-29 specifies age-related differences in the CD8+ T cell immune response..
37.
2021
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Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease..
37.
2021
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Structural and compositional diversity in the kainate receptor family..
37.
2021
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Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting..
37.
2021
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Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting..
37.
2021
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An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection.
2021
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Attenuation of apoptotic cell detection triggers thymic regeneration after damage..
37.
2021
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Role of miR-2392 in driving SARS-CoV-2 infection.
2021
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Multiplexed functional metagenomic analysis of the infant microbiome identifies effectors of NF-κB, autophagy, and cellular redox state..
36.
2021
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Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo..
36.
2021
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Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity..
36.
2021
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Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy..
36.
2021
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Methylation of dual-specificity phosphatase 4 controls cell differentiation..
36.
2021
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Molecular control of cell density-mediated exit to quiescence..
36.
2021
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FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes..
35.
2021
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Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination..
35.
2021
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MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages..
35.
2021
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NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma..
35.
2021
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Mammalian cells use the autophagy process to restrict avian influenza virus replication..
35.
2021
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Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system..
35.
2021
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Mechanisms of differential desensitization of metabotropic glutamate receptors..
35.
2021
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A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients..
35.
2021
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Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike..
35.
2021
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Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity..
35.
2021
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Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice..
34.
2021
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Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine..
34.
2021
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Topographical organization of mammillary neurogenesis and efferent projections in the mouse brain..
34.
2021
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Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway..
34.
2021
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Acute stress drives global repression through two independent RNA polymerase II stalling events in Saccharomyces..
34.
2021
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HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies..
34.
2021
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Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma..
34.
2021
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Tet Proteins Regulate Neutrophil Granulation in Zebrafish through Demethylation of socs3b mRNA..
34.
2021
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Rapid Precision Functional Mapping of Individuals Using Multi-Echo fMRI..
33.
2020
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Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells..
33.
2020
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An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2..
33.
2020
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Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer..
33.
2020
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Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development..
33.
2020
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Clonal Hematopoiesis Before, During, and After Human Spaceflight..
33.
2020
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Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity..
33.
2020
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Telomere Length Dynamics and DNA Damage Responses Associated with Long-Duration Spaceflight..
33.
2020
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Temporal Telomere and DNA Damage Responses in the Space Radiation Environment..
33.
2020
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Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures..
33.
2020
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Temporal Analysis of Brd4 Displacement in the Control of B Cell Survival, Proliferation, and Differentiation..
33.
2020
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TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment..
33.
2020
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Actin R256 Mono-methylation Is a Conserved Post-translational Modification Involved in Transcription..
32.
2020
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Comparison of Human Antral Follicles of Xenograft versus Ovarian Origin Reveals Disparate Molecular Signatures..
32.
2020
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Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury..
31.
2020
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Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus..
31.
2020
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Molecular Competition in G1 Controls When Cells Simultaneously Commit to Terminally Differentiate and Exit the Cell Cycle..
31.
2020
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Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells..
31.
2020
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Defining the Homo- and Heterodimerization Propensities of Metabotropic Glutamate Receptors..
31.
2020
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Extracellular Acidosis and mTOR Inhibition Drive the Differentiation of Human Monocyte-Derived Dendritic Cells..
31.
2020
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Knocking Out Non-muscle Myosin II in Retinal Ganglion Cells Promotes Long-Distance Optic Nerve Regeneration..
31.
2020
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A Susceptibility Locus on Chromosome 13 Profoundly Impacts the Stability of Genomic Imprinting in Mouse Pluripotent Stem Cells..
30.
2020
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ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms..
30.
2020
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Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures..
30.
2020
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Single-Cell Analysis of the Muscle Stem Cell Hierarchy Identifies Heterotypic Communication Signals Involved in Skeletal Muscle Regeneration..
30.
2020
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Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates..
30.
2020
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Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization..
30.
2020
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Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer..
30.
2020
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Identification of Antibodies Targeting the H3N2 Hemagglutinin Receptor Binding Site following Vaccination of Humans..
29.
2019
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Tissue-Resident Memory T Cells Mediate Immune Homeostasis in the Human Pancreas through the PD-1/PD-L1 Pathway..
29.
2019
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A Deep Learning Framework for Predicting Response to Therapy in Cancer..
29.
2019
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Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks..
29.
2019
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CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer..
29.
2019
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Lipocalin-2 Regulates Epidermal Growth Factor Receptor Intracellular Trafficking..
29.
2019
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NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells..
29.
2019
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Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia..
29.
2019
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Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients..
29.
2019
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m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment..
28.
2019
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AGO CLIP Reveals an Activated Network for Acute Regulation of Brain Glutamate Homeostasis in Ischemic Stroke..
28.
2019
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Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons..
28.
2019
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MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition..
28.
2019
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PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism..
27.
2019
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Distinct Requirements of CHD4 during B Cell Development and Antibody Response..
27.
2019
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Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate..
27.
2019
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Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer..
27.
2019
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Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphocholine Lipids Support Cytokine Induction in Response to Fungal Patterns..
27.
2019
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HIV Controllers Exhibit Effective CD8+ T Cell Recognition of HIV-1-Infected Non-activated CD4+ T Cells..
27.
2019
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Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells..
26.
2019
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Modeling Patient-Derived Glioblastoma with Cerebral Organoids..
26.
2019
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Exercise Alleviates Obesity-Induced Metabolic Dysfunction via Enhancing FGF21 Sensitivity in Adipose Tissues..
26.
2019
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Diurnal Rhythms Spatially and Temporally Organize Autophagy..
26.
2019
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Mapping the Human Kinome in Response to DNA Damage..
26.
2019
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TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis..
26.
2019
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Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD..
26.
2019
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LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux..
25.
2018
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Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer..
25.
2018
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CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques..
25.
2018
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tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis..
25.
2018
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Early Life Stress Drives Sex-Selective Impairment in Reversal Learning by Affecting Parvalbumin Interneurons in Orbitofrontal Cortex of Mice..
25.
2018
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A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates..
25.
2018
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IFNα Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion..
25.
2018
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NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus..
25.
2018
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RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss..
25.
2018
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Endogenous rRNA Sequence Variation Can Regulate Stress Response Gene Expression and Phenotype..
25.
2018
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Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq..
24.
2018
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Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen..
24.
2018
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Three Distinct Sets of Connector Hubs Integrate Human Brain Function..
24.
2018
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OX40 Costimulation Inhibits Foxp3 Expression and Treg Induction via BATF3-Dependent and Independent Mechanisms..
24.
2018
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Anti-microbial Functions of Group 3 Innate Lymphoid Cells in Gut-Associated Lymphoid Tissues Are Regulated by G-Protein-Coupled Receptor 183..
23.
2018
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An Amphipathic Helix Directs Cellular Membrane Curvature Sensing and Function of the BAR Domain Protein PICK1..
23.
2018
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Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System..
23.
2018
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Corticospinal Circuits from the Sensory and Motor Cortices Differentially Regulate Skilled Movements through Distinct Spinal Interneurons..
23.
2018
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The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer..
23.
2018
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Global Cancer Transcriptome Quantifies Repeat Element Polarization between Immunotherapy Responsive and T Cell Suppressive Classes..
23.
2018
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How Biophysical Forces Regulate Human B Cell Lymphomas..
23.
2018
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ERRγ Preserves Brown Fat Innate Thermogenic Activity..
22.
2018
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GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma..
22.
2018
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Netrin-1 Confines Rhombic Lip-Derived Neurons to the CNS..
22.
2018
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CD209a Synergizes with Dectin-2 and Mincle to Drive Severe Th17 Cell-Mediated Schistosome Egg-Induced Immunopathology..
22.
2018
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TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis..
22.
2018
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Nascent Induced Pluripotent Stem Cells Efficiently Generate Entirely iPSC-Derived Mice while Expressing Differentiation-Associated Genes..
22.
2018
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Loss of an Androgen-Inactivating and Isoform-Specific HSD17B4 Splice Form Enables Emergence of Castration-Resistant Prostate Cancer..
22.
2018
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Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle..
21.
2017
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Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing..
21.
2017
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ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival..
21.
2017
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Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure..
21.
2017
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Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2..
21.
2017
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Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport..
21.
2017
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A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas..
21.
2017
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Differential Regulation of Lipoprotein and Hepatitis C Virus Secretion by Rab1b..
21.
2017
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Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection..
21.
2017
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Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity..
20.
2017
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Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons..
20.
2017
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Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites..
20.
2017
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Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer..
20.
2017
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Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization..
20.
2017
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An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis..
20.
2017
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Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin..
19.
2017
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Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation..
19.
2017
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Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E..
19.
2017
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Widespread Mitotic Bookmarking by Histone Marks and Transcription Factors in Pluripotent Stem Cells..
19.
2017
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HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue-Destructive Phenotype..
19.
2017
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The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma..
18.
2017
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Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma..
18.
2017
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Primary Cell Culture of Live Neurosurgically Resected Aged Adult Human Brain Cells and Single Cell Transcriptomics..
18.
2017
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BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation..
18.
2017
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Adenovirus Protein E4-ORF1 Activation of PI3 Kinase Reveals Differential Regulation of Downstream Effector Pathways in Adipocytes..
17.
2016
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Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells..
17.
2016
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The Ciliary Margin Zone of the Mammalian Retina Generates Retinal Ganglion Cells..
17.
2016
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Downregulation of a GPCR by β-Arrestin2-Mediated Switch from an Endosomal to a TGN Recycling Pathway..
17.
2016
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Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome..
17.
2016
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Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer..
17.
2016
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Requirement for Dicer in Maintenance of Monosynaptic Sensory-Motor Circuits in the Spinal Cord..
17.
2016
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Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1..
17.
2016
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Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies..
17.
2016
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Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι..
16.
2016
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IFN-γ Induces Histone 3 Lysine 27 Trimethylation in a Small Subset of Promoters to Stably Silence Gene Expression in Human Macrophages..
16.
2016
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Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies..
16.
2016
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Integrated Patient-Derived Models Delineate Individualized Therapeutic Vulnerabilities of Pancreatic Cancer..
16.
2016
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miR-17-92 Cluster Regulates Adult Hippocampal Neurogenesis, Anxiety, and Depression..
16.
2016
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Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells..
16.
2016
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A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors..
15.
2016
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CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN..
15.
2016
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Discovery of a Small-Molecule BMP Sensitizer for Human Embryonic Stem Cell Differentiation..
15.
2016
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Optimal ROS Signaling Is Critical for Nuclear Reprogramming..
15.
2016
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HDAC3 Is a Master Regulator of mTEC Development..
15.
2016
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G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells..
15.
2016
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Smurf1 Inhibits Osteoblast Differentiation, Bone Formation, and Glucose Homeostasis through Serine 148..
15.
2016
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Structural Model of the Extracellular Assembly of the TCR-CD3 Complex..
14.
2016
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Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein..
14.
2016
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Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma..
14.
2016
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Intralymphatic CCL21 Promotes Tissue Egress of Dendritic Cells through Afferent Lymphatic Vessels..
14.
2016
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MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4..
14.
2016
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Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis..
14.
2016
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Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site..
14.
2015
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A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species..
13.
2015
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Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors..
13.
2015
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The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis..
13.
2015
-
Apical versus Basal Neurogenesis Directs Cortical Interneuron Subclass Fate..
13.
2015
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Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3' Splice Site Selection through Use of a Different Branch Point..
13.
2015
-
Discovery and Characterization of piRNAs in the Human Fetal Ovary..
13.
2015
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Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence..
13.
2015
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TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response..
13.
2015
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Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner..
13.
2015
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DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID..
12.
2015
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Disabling of the erbB Pathway Followed by IFN-γ Modifies Phenotype and Enhances Genotoxic Eradication of Breast Tumors..
12.
2015
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PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells..
12.
2015
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Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade..
12.
2015
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Intestinal Monocyte-Derived Macrophages Control Commensal-Specific Th17 Responses..
12.
2015
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Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence..
12.
2015
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The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer..
12.
2015
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Dynamics of Tumor Heterogeneity Derived from Clonal Karyotypic Evolution..
12.
2015
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Quantitative Proteomics Identifies Serum Response Factor Binding Protein 1 as a Host Factor for Hepatitis C Virus Entry..
12.
2015
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Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia..
12.
2015
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mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation..
12.
2015
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Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers..
11.
2015
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The Cell-Intrinsic Circadian Clock Is Dispensable for Lymphocyte Differentiation and Function..
11.
2015
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Composite macroH2A/NRF-1 Nucleosomes Suppress Noise and Generate Robustness in Gene Expression..
11.
2015
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Porous silicon microparticle potentiates anti-tumor immunity by enhancing cross-presentation and inducing type I interferon response..
11.
2015
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A systems approach identifies networks and genes linking sleep and stress: implications for neuropsychiatric disorders..
11.
2015
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Central role of ULK1 in type I interferon signaling..
11.
2015
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Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model..
10.
2015
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Systematic Discovery of Human Gene Function and Principles of Modular Organization through Phylogenetic Profiling..
10.
2015
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Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ..
10.
2015
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Network Diffusion Model of Progression Predicts Longitudinal Patterns of Atrophy and Metabolism in Alzheimer's Disease..
10.
2015
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ELAVL1 modulates transcriptome-wide miRNA binding in murine macrophages..
9.
2014
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p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche..
9.
2014
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DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia..
9.
2014
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Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma..
9.
2014
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ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling..
9.
2014
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A cell engineering strategy to enhance the safety of stem cell therapies..
8.
2014
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Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition..
8.
2014
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Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA..
8.
2014
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PTEN interacts with histone H1 and controls chromatin condensation..
8.
2014
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The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers..
8.
2014
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Nontranscriptional role of Hif-1α in activation of γ-secretase and notch signaling in breast cancer..
8.
2014
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The BRCA1-interacting protein Abraxas is required for genomic stability and tumor suppression..
8.
2014
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A comprehensive and high-resolution genome-wide response of p53 to stress..
8.
2014
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MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice..
8.
2014
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IKKα promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells..
7.
2014
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Growth of the developing cerebral cortex is controlled by microRNA-7 through the p53 pathway..
7.
2014
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CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer..
7.
2014
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proBDNF negatively regulates neuronal remodeling, synaptic transmission, and synaptic plasticity in hippocampus..
7.
2014
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Death induced by CD95 or CD95 ligand elimination..
7.
2014
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De novo formation of insulin-producing "neo-β cell islets" from intestinal crypts..
6.
2014
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HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism..
6.
2014
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PTEN C-terminal deletion causes genomic instability and tumor development..
6.
2014
-
ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia..
6.
2014
-
ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state..
6.
2014
-
Genetics of follicular lymphoma transformation..
6.
2014
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Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling..
6.
2013
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Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis..
6.
2013
-
PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex..
5.
2013
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TGF-β-Id1 signaling opposes Twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition..
5.
2013
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Specification of functional cranial placode derivatives from human pluripotent stem cells..
5.
2013
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Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors..
5.
2013
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Specificity of monosynaptic sensory-motor connections imposed by repellent Sema3E-PlexinD1 signaling..
5.
2013
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A chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2..
5.
2013
-
Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis..
4.
2013
-
SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres..
4.
2013
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A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters..
4.
2013
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FGF14 regulates presynaptic Ca2+ channels and synaptic transmission..
4.
2013
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A genome-wide map of CTCF multivalency redefines the CTCF code..
3.
2013
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Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state..
3.
2013
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Sunitinib does not accelerate tumor growth in patients with metastatic renal cell carcinoma..
3.
2013
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RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction..
3.
2013
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Tracing conidial fate and measuring host cell antifungal activity using a reporter of microbial viability in the lung..
2.
2012
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Consecutive positive feedback loops create a bistable switch that controls preadipocyte-to-adipocyte conversion..
2.
2012
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Prognostic impact of vitamin B6 metabolism in lung cancer..
2.
2012
-
Age-related oxidative stress compromises endosomal proteostasis..
2.
2012
-
Thermosensory and nonthermosensory isoforms of Drosophila melanogaster TRPA1 reveal heat-sensor domains of a thermoTRP Channel..
1.
2012
-
Retraction Notice to: mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation..
42.
2023
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PSMB11 regulates gene expression in cortical thymic epithelial cells.
2021
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3D enhancer-promoter interactions and multi-connected hubs: Organizational principles and functional roles.
2023
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