Journal of immunology (Baltimore, Md. : 1950)

publication venue for

Expressions of Concern: Reprogramming of IL-10 Activity and Signaling by IFN-γ. 2023
Ebi3 Binding to IFN-γ and IL-10 Limits Their Function. 2024
ICOS-expressing Regulatory T Cells Influence the Composition of Antitumor CTL Populations. 2024
CD8+ T Cell-Dependent Antitumor Activity In Vivo of a Mass Spectrometry-Identified Neoepitope despite Undetectable CD8+ Immunogenicity In Vitro.. 211. 2023
Jagged1 Acts as an RBP-J Target and Feedback Suppresses TNF-Mediated Inflammatory Osteoclastogenesis. 2023
Cutting Edge: Optimal Formation of Hepatic Tissue-Resident Memory CD4 T Cells Requires T-bet Regulation of CD18. 2023
CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated. 2023
Building on the Past, Meeting the Moment.. 210. 2023
Cutting Edge: Neutrophil Complement Receptor Signaling Is Required for BAFF-Dependent Humoral Responses in Mice.. 210. 2023
Protein Kinase CK2 Controls CD8⁺ T Cell Effector and Memory Function during Infection. 2022
ICOS-Deficient Regulatory T Cells Can Prevent Spontaneous Autoimmunity but Are Impaired in Controlling Acute Inflammation.. 209. 2022
High-Fat Diet-Induced Obesity Alters Dendritic Cell Homeostasis by Enhancing Mitochondrial Fatty Acid Oxidation.. 209. 2022
Fungal Patterns Induce Cytokine Expression through Fluxes of Metabolic Intermediates That Support Glycolysis and Oxidative Phosphorylation.. 208. 2022
Single-Cell Transcriptional Profiling Reveals Signatures of Helper, Effector, and Regulatory MAIT Cells during Homeostasis and Activation. 2022
Regulation of Cutaneous Immunity In Vivo by Calcitonin Gene-Related Peptide Signaling through Endothelial Cells. 2022
Prosurvival IL-7-Stimulated Weak Strength of mTORC1-S6K Controls T Cell Memory via Transcriptional FOXO1-TCF1-Id3 and Metabolic AMPKα1-ULK1-ATG7 Pathways.. 208. 2021
Human Cytomegalovirus Infection Promotes Expansion of a Functionally Superior Cytoplasmic CD3⁺ NK Cell Subset with a Bcl11b-Regulated T Cell Signature.. 207. 2021
Cutting Edge: Intestinal IL-17A Receptor Signaling Specifically Regulates High-Fat Diet-Mediated, Microbiota-Driven Metabolic Disorders.. 207. 2021
Noncytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells In Vitro and Suppresses Cutaneous Inflammation in the Mouse.. 206. 2021
Nrf2 through Aryl Hydrocarbon Receptor Regulates IL-22 Response in CD4⁺ T Cells.. 206. 2021
Conceiving the Inconceivable: The Function of Aire in Immune Tolerance to Peripheral Tissue-Restricted Antigens in the Thymus.. 206. 2021
IL-7Rα^low CD8⁺ T Cells from Healthy Individuals Are Anergic with Defective Glycolysis.. 205. 2020
Hepcidin Is Essential for Alveolar Macrophage Function and Is Disrupted by Smoke in a Murine Chronic Obstructive Pulmonary Disease Model.. 205. 2020
Maintenance of Germinal Center B Cells by Caspase-9 through Promotion of Apoptosis and Inhibition of Necroptosis.. 205. 2020
Bmi1 Maintains the Self-Renewal Property of Innate-like B Lymphocytes.. 204. 2020
4E-BP-Dependent Translational Control of Irf8 Mediates Adipose Tissue Macrophage Inflammatory Response.. 204. 2020
TNF-Induced Interstitial Lung Disease in a Murine Arthritis Model: Accumulation of Activated Monocytes, Conventional Dendritic Cells, and CD21⁺/CD23^- B Cell Follicles Is Prevented with Anti-TNF Therapy.. 203. 2019
Identification of a Novel Role for Foxo3 Isoform2 in Osteoclastic Inhibition.. 203. 2019
Lymphatic Cannulation for Lymph Sampling and Molecular Delivery.. 203. 2019
The Selective Expansion and Targeted Accumulation of Bone Marrow-Derived Macrophages Drive Cardiac Vasculitis.. 202. 2019
Nur77 Links Chronic Antigen Stimulation to B Cell Tolerance by Restricting the Survival of Self-Reactive B Cells in the Periphery.. 202. 2019
Identification of the E3 Ligase TRIM29 as a Critical Checkpoint Regulator of NK Cell Functions. 203:873-880. 2019
Charcot-Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1β Inflammation in Human Macrophages.. 202. 2018
Hippo Pathway Kinase Mst1 Is Required for Long-Lived Humoral Immunity.. 202. 2018
CK2 Controls Th17 and Regulatory T Cell Differentiation Through Inhibition of FoxO1.. 201. 2018
TRIM29 Negatively Regulates the Type I IFN Production in Response to RNA Virus.. 201. 2018
HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression.. 200. 2018
ICOS Signaling Controls Induction and Maintenance of Collagen-Induced Arthritis.. 200. 2018
Golgi Phosphoprotein 2 Is a Novel Regulator of IL-12 Production and Macrophage Polarization.. 200. 2018
TRIM29 Negatively Regulates the Type I IFN Production in Response to RNA Virus. 201:183-192. 2018
The Loss of TET2 Promotes CD8⁺ T Cell Memory Differentiation.. 200. 2017
Mesenchymal Cell-Specific MyD88 Signaling Promotes Systemic Dissemination of Salmonella Typhimurium via Inflammatory Monocytes.. 199. 2017
Elimination of Babesia microti Is Dependent on Intraerythrocytic Killing and CD4⁺ T Cells.. 199. 2017
Protein Kinase CK2 Controls the Fate between Th17 Cell and Regulatory T Cell Differentiation.. 198. 2017
Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.. 198. 2017
Expression of IL-22 in the Skin Causes Th2-Biased Immunity, Epidermal Barrier Dysfunction, and Pruritus via Stimulating Epithelial Th2 Cytokines and the GRP Pathway.. 198. 2017
An Infectious Disease-Associated Il12b Polymorphism Regulates IL-12/23 p40 Transcription Involving Poly(ADP-Ribose) Polymerase 1.. 198. 2017
Circulating and Exosome-Packaged Hepatitis C Single-Stranded RNA Induce Monocyte Differentiation via TLR7/8 to Polarized Macrophages and Fibrocytes.. 198. 2017
Transcriptional Repression of IFN Regulatory Factor 7 by MYC Is Critical for Type I IFN Production in Human Plasmacytoid Dendritic Cells.. 197. 2016
Progranulin Controls Sepsis via C/EBPα-Regulated Il10 Transcription and Ubiquitin Ligase/Proteasome-Mediated Protein Degradation.. 197. 2016
Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia.. 197. 2016
Rpl22 Loss Selectively Impairs αβ T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling.. 197. 2016
Zinc Induces Dendritic Cell Tolerogenic Phenotype and Skews Regulatory T Cell-Th17 Balance.. 197. 2016
RBP-J-Regulated miR-182 Promotes TNF-α-Induced Osteoclastogenesis.. 196. 2016
Cutting Edge: EZH2 Promotes Osteoclastogenesis by Epigenetic Silencing of the Negative Regulator IRF8.. 196. 2016
POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes.. 196. 2016
Calcitonin Gene-Related Peptide-Exposed Endothelial Cells Bias Antigen Presentation to CD4+ T Cells toward a Th17 Response.. 196. 2016
Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System.. 196. 2016
Reactivation of Neutralized HIV-1 by Dendritic Cells Is Dependent on the Epitope Bound by the Antibody.. 195. 2015
The Blood Transcriptome of Experimental Melioidosis Reflects Disease Severity and Shows Considerable Similarity with the Human Disease.. 195. 2015
Restoration of CD4+ Responses to Copathogens in HIV-Infected Individuals on Antiretroviral Therapy Is Dependent on T Cell Memory Phenotype.. 195. 2015
IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with Age.. 195. 2015
Prevention of Defective Placentation and Pregnancy Loss by Blocking Innate Immune Pathways in a Syngeneic Model of Placental Insufficiency.. 195. 2015
Cutting edge: CD69 interference with sphingosine-1-phosphate receptor function regulates peripheral T cell retention.. 194. 2015
NFAT1 and JunB cooperatively regulate IL-31 gene expression in CD4+ T cells in health and disease.. 194. 2015
Antigen recognition in the islets changes with progression of autoimmune islet infiltration.. 194. 2014
Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques.. 193. 2014
mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.. 193. 2014
The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation.. 193. 2014
Basophils promote innate lymphoid cell responses in inflamed skin.. 193. 2014
Modulation of TNF-induced macrophage polarization by synovial fibroblasts.. 193. 2014
Inducible nitric oxide synthase in neutrophils and endothelium contributes to ischemic brain injury in mice.. 193. 2014
DHX15 senses double-stranded RNA in myeloid dendritic cells.. 193. 2014
IFN priming is necessary but not sufficient to turn on a migratory dendritic cell program in lupus monocytes.. 192. 2014
Autoantibodies induced by chimeric cytokine-HIV envelope glycoprotein immunogens.. 192. 2014
SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter.. 192. 2014
Multiple CD11c+ cells collaboratively express IL-1β to modulate stromal vascular endothelial growth factor and lymph node vascular-stromal growth.. 192. 2014
IL-13 orchestrates resolution of chronic intestinal inflammation via phosphorylation of glycogen synthase kinase-3β.. 192. 2014
NF90 exerts antiviral activity through regulation of PKR phosphorylation and stress granules in infected cells.. 192. 2014
Three tapasin docking sites in TAP cooperate to facilitate transporter stabilization and heterodimerization.. 192. 2014
Hydrogen sulfide [corrected] increases survival during sepsis: protective effect of CHOP inhibition.. 192. 2014
T cell Ig and mucin domain-containing protein 3 is recruited to the immune synapse, disrupts stable synapse formation, and associates with receptor phosphatases.. 192. 2013
IL-6-mediated induction of matrix metalloproteinase-9 is modulated by JAK-dependent IL-10 expression in macrophages.. 192. 2013
Cholinergic receptors modulate immune complex-induced inflammation in vitro and in vivo.. 191. 2013
Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice.. 191. 2013
SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection.. 191. 2013
Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells.. 190. 2013
Adam8 limits the development of allergic airway inflammation in mice.. 190. 2013
A dynamic dual role of IL-2 signaling in the two-step differentiation process of adaptive regulatory T cells.. 190. 2013
Potent induction of antibody-secreting B cells by human dermal-derived CD14+ dendritic cells triggered by dual TLR ligation.. 189. 2012
HIV-1 gp120 impairs the induction of B cell responses by TLR9-activated plasmacytoid dendritic cells.. 189. 2012
Airway epithelial expression of TLR5 is downregulated in healthy smokers and smokers with chronic obstructive pulmonary disease.. 189. 2012
Targeting Stat3 induces senescence in tumor cells and elicits prophylactic and therapeutic immune responses against breast cancer growth mediated by NK cells and CD4+ T cells.. 189. 2012
Stromal endothelial cells establish a bidirectional crosstalk with chronic lymphocytic leukemia cells through the TNF-related factors BAFF, APRIL, and CD40L.. 188. 2012
BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses.. 188. 2012
Beyond HLA-A*0201: new HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8+ T cell epitopes.. 188. 2012
ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes.. 188. 2012
Maintenance of T cell function in the face of chronic antigen stimulation and repeated reactivation for a latent virus infection.. 188. 2012
Matrix metalloproteinase-dependent microsomal prostaglandin E synthase-1 expression in macrophages: role of TNF-α and the EP4 prostanoid receptor.. 188. 2012
Cutting edge: Nicastrin and related components of γ-secretase generate a peptide epitope facilitating immune recognition of intracellular mycobacteria, through MHC class II-dependent priming of T cells.. 187. 2011
Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells.. 187. 2011
DHX9 pairs with IPS-1 to sense double-stranded RNA in myeloid dendritic cells.. 187. 2011
HIV-1 N-glycan composition governs a balance between dendritic cell-mediated viral transmission and antigen presentation.. 187. 2011
The SLP-76 Src homology 2 domain is required for T cell development and activation.. 187. 2011
Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients.. 187. 2011
Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis.. 187. 2011
Developmental arrest of T cells in Rpl22-deficient mice is dependent upon multiple p53 effectors.. 187. 2011
A unique hybrid renal mononuclear phagocyte activation phenotype in murine systemic lupus erythematosus nephritis.. 186. 2011
Requirements for eomesodermin and promyelocytic leukemia zinc finger in the development of innate-like CD8+ T cells.. 186. 2011
Secretory leukocyte protease inhibitor plays an important role in the regulation of allergic asthma in mice.. 186. 2011
CCR5 blockade in combination with cyclosporine increased cardiac graft survival and generated alternatively activated macrophages in primates.. 186. 2011
Muramyl dipeptide induces Th17 polarization through activation of endothelial cells.. 186. 2011
B lymphocytes differentially influence acute and chronic allograft rejection in mice.. 186. 2011
On/off TLR signaling decides proinflammatory or tolerogenic dendritic cell maturation upon CD1d-mediated interaction with invariant NKT cells.. 185. 2010
Cutting edge: Virus-specific CD8+ T cell clones and the maintenance of replicative function during a persistent viral infection.. 185. 2010
Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys.. 185. 2010
Suppression of TNF-α and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27.. 185. 2010
Direct inhibition of human RANK+ osteoclast precursors identifies a homeostatic function of IL-1beta.. 185. 2010
Rapid generation of rotavirus-specific human monoclonal antibodies from small-intestinal mucosa.. 185. 2010
Naive human T cells are activated and proliferate in response to the heme oxygenase-1 inhibitor tin mesoporphyrin.. 185. 2010
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1.. 185. 2010
IL-2 mRNA stabilization upon PMA stimulation is dependent on NF90-Ser647 phosphorylation by protein kinase CbetaI.. 185. 2010
Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages.. 185. 2010
Dendritic cells induce regulatory T cell proliferation through antigen-dependent and -independent interactions.. 185. 2010
Carbon monoxide suppresses membrane expression of TLR4 via myeloid differentiation factor-2 in betaTC3 cells.. 185. 2010
Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease.. 185. 2010
The relative timing of exposure to phagocytosable particulates and to osteoclastogenic cytokines is critically important in the determination of myeloid cell fate.. 185. 2010
Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150).. 185. 2010
"Default" generation of neonatal regulatory T cells.. 185. 2010
CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells.. 184. 2010
Calcium-activated pathways and oxidative burst mediate zymosan-induced signaling and IL-10 production in human macrophages.. 184. 2010
miR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation.. 184. 2010
CD11c(hi) dendritic cells regulate the re-establishment of vascular quiescence and stabilization after immune stimulation of lymph nodes.. 184. 2010
Triptolide inhibits IL-12/IL-23 expression in APCs via CCAAT/enhancer-binding protein alpha.. 184. 2010
The septic shock-associated IL-10 -1082 A > G polymorphism mediates allele-specific transcription via poly(ADP-Ribose) polymerase 1 in macrophages engulfing apoptotic cells.. 184. 2010
Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block.. 184. 2010
Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.. 184. 2009
Cutting edge: depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice.. 183. 2009
Matrix metalloproteinase (MMP)-1 and MMP-3 induce macrophage MMP-9: evidence for the role of TNF-alpha and cyclooxygenase-2.. 183. 2009
The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response.. 183. 2009
Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN-gamma in human osteoclast precursors.. 183. 2009
Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses.. 183. 2009
Reducing epitope spread during affinity maturation of an anti-ganglioside GD2 antibody.. 183. 2009
Characterization of preexisting MAGE-A3-specific CD4+ T cells in cancer patients and healthy individuals and their activation by protein vaccination.. 183. 2009
A panel of artificial APCs expressing prevalent HLA alleles permits generation of cytotoxic T cells specific for both dominant and subdominant viral epitopes for adoptive therapy.. 183. 2009
Distinct responses of human monocyte subsets to Aspergillus fumigatus conidia.. 183. 2009
Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease.. 183. 2009
IL-10 suppresses calcium-mediated costimulation of receptor activator NF-kappa B signaling during human osteoclast differentiation by inhibiting TREM-2 expression.. 183. 2009
The lytic potential of human liver NK cells is restricted by their limited expression of inhibitory killer Ig-like receptors.. 183. 2009
SUMO conjugation contributes to immune deviation in nonobese diabetic mice by suppressing c-Maf transactivation of IL-4.. 183. 2009
Tuberculosis is associated with a down-modulatory lung immune response that impairs Th1-type immunity.. 183. 2009
Ectodomain shedding of FLT3 ligand is mediated by TNF-alpha converting enzyme.. 182. 2009
Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1.. 182. 2009
Cutting edge: rescue of pre-TCR but not mature TCR signaling in mice expressing membrane-targeted SLP-76.. 182. 2009
Luteinizing hormone-releasing hormone enhances T cell recovery following allogeneic bone marrow transplantation.. 182. 2009
Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point.. 182. 2009
Inducible MHC class II expression by mast cells supports effector and regulatory T cell activation.. 182. 2009
The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1.. 182. 2009
Accelerated pathological and clinical nephritis in systemic lupus erythematosus-prone New Zealand Mixed 2328 mice doubly deficient in TNF receptor 1 and TNF receptor 2 via a Th17-associated pathway.. 182. 2009
Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.. 182. 2009
CDK2 phosphorylation of Smad2 disrupts TGF-beta transcriptional regulation in resistant primary bone marrow myeloma cells.. 182. 2009
Conditional inactivation of TACE by a Sox9 promoter leads to osteoporosis and increased granulopoiesis via dysregulation of IL-17 and G-CSF.. 182. 2009
Human liver dendritic cells promote T cell hyporesponsiveness.. 182. 2009
Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo.. 182. 2009
Calcitonin gene-related peptide biases Langerhans cells toward Th2-type immunity.. 181. 2008
Decreased expression of intelectin 1 in the human airway epithelium of smokers compared to nonsmokers.. 181. 2008
Lipopolysaccharide-induced expression of matrix metalloproteinases in human monocytes is suppressed by IFN-gamma via superinduction of ATF-3 and suppression of AP-1.. 181. 2008
T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C theta.. 181. 2008
Fibroblast-type reticular stromal cells regulate the lymph node vasculature.. 181. 2008
Memory B cells and pneumococcal antibody after splenectomy.. 181. 2008
Potent simian immunodeficiency virus-specific cellular immune responses in the breast milk of simian immunodeficiency virus-infected, lactating rhesus monkeys.. 181. 2008
Differential requirement for the SAP-Fyn interaction during NK T cell development and function.. 181. 2008
Modulation of T cell activation by stomatin-like protein 2.. 181. 2008
Mutational characterization of pancreatitis-associated protein 2 domains involved in mediating cytokine secretion in macrophages and the NF-kappaB pathway.. 181. 2008
Pancreatitis-associated protein 2 modulates inflammatory responses in macrophages.. 181. 2008
Impaired SLAM-SLAM homotypic interaction between invariant NKT cells and dendritic cells affects differentiation of IL-4/IL-10-secreting NKT2 cells in nonobese diabetic mice.. 181. 2008
Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant.. 181. 2008
IFN-gamma and STAT1 arrest monocyte migration and modulate RAC/CDC42 pathways.. 180. 2008
IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38.. 180. 2008
Nuclear export of NF90 to stabilize IL-2 mRNA is mediated by AKT-dependent phosphorylation at Ser647 in response to CD28 costimulation.. 180. 2008
Cell surface colony-stimulating factor 1 can be cleaved by TNF-alpha converting enzyme or endocytosed in a clathrin-dependent manner.. 179. 2007
NK dendritic cells expanded in IL-15 exhibit antitumor responses in vivo.. 179. 2007
Antigen transmission by replicating antigen-bearing dendritic cells.. 179. 2007
Cutting edge: TNF-alpha-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock.. 179. 2007
Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys.. 179. 2007
Human blood-brain barrier disruption by retroviral-infected lymphocytes: role of myosin light chain kinase in endothelial tight-junction disorganization.. 179. 2007
Phospholipase cbeta is critical for T cell chemotaxis.. 179. 2007
Both infiltrating regulatory T cells and insufficient antigen presentation are involved in long-term cardiac xenograft survival.. 179. 2007
Cutting edge: Transitional T3 B cells do not give rise to mature B cells, have undergone selection, and are reduced in murine lupus.. 178. 2007
Immune cross-reactivity in celiac disease: anti-gliadin antibodies bind to neuronal synapsin I.. 178. 2007
Loss of SLP-76 expression within myeloid cells confers resistance to neutrophil-mediated tissue damage while maintaining effective bacterial killing.. 178. 2007
Mouse TCRalphabeta+CD8alphaalpha intraepithelial lymphocytes express genes that down-regulate their antigen reactivity and suppress immune responses.. 178. 2007
NK dendritic cells are innate immune responders to Listeria monocytogenes infection.. 178. 2007
Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs.. 178. 2007
IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation.. 178. 2007
Regulated expression of FcgammaR in human dendritic cells controls cross-presentation of antigen-antibody complexes.. 177. 2006
Oligomerization of CXCL10 is necessary for endothelial cell presentation and in vivo activity.. 177. 2006
An unconventional antigen translated by a novel internal ribosome entry site elicits antitumor humoral immune reactions.. 177. 2006
Identification and characterization of the precursors committed to osteoclasts induced by TNF-related activation-induced cytokine/receptor activator of NF-kappa B ligand.. 177. 2006
The reduced bactericidal function of complement C5-deficient murine macrophages is associated with defects in the synthesis and delivery of reactive oxygen radicals to mycobacterial phagosomes.. 177. 2006
DNA immunization against tissue-restricted antigens enhances tumor immunity after allogeneic hemopoietic stem cell transplantation.. 177. 2006
Double-negative T regulatory cells can develop outside the thymus and do not mature from CD8+ T cell precursors.. 177. 2006
Processing and presentation of a mycobacterial antigen 85B epitope by murine macrophages is dependent on the phagosomal acquisition of vacuolar proton ATPase and in situ activation of cathepsin D.. 177. 2006
FcR gamma presence in TCR complex of double-negative T cells is critical for their regulatory function.. 177. 2006
Paucity of clinical disease despite serological autoimmunity and kidney pathology in lupus-prone New Zealand mixed 2328 mice deficient in BAFF.. 177. 2006
Characterization of human complement receptor type 2 (CR2/CD21) as a receptor for IFN-alpha: a potential role in systemic lupus erythematosus.. 177. 2006
Biliary obstruction selectively expands and activates liver myeloid dendritic cells.. 176. 2006
In situ replication of immediate dendritic cell (DC) precursors contributes to conventional DC homeostasis in lymphoid tissue.. 176. 2006
Adhesion- and degranulation-promoting adapter protein is required for efficient thymocyte development and selection.. 176. 2006
Costimulation of chemokine receptor signaling by matrix metalloproteinase-9 mediates enhanced migration of IFN-alpha dendritic cells.. 176. 2006
A role for the MutL mismatch repair Mlh3 protein in immunoglobulin class switch DNA recombination and somatic hypermutation.. 176. 2006
CXCR5/CXCL13 interaction is important for double-negative regulatory T cell homing to cardiac allografts.. 176. 2006
Selective regulation of IL-10 signaling and function by zymosan.. 176. 2006
HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors.. 176. 2006
Antibody-induced transplantation tolerance that is dependent on thymus-derived regulatory T cells.. 176. 2006
Antigen exposure during enhanced CTLA-4 expression promotes allograft tolerance in vivo.. 176. 2006
Functional hierarchy of the N-terminal tyrosines of SLP-76.. 176. 2006
Langerhans-type dendritic cells genetically modified to express full-length antigen optimally stimulate CTLs in a CD4-dependent manner.. 176. 2006
Inhibition of TCR signaling by herpes simplex virus.. 176. 2006
Abrupt expression of TLR4 in TLR4-deficient macrophages imposes a selective disadvantage: genetic evidence for TLR4-dependent responses to endogenous, nonmicrobial stimuli.. 176. 2006
Early growth response-1 is required for CD154 transcription.. 176. 2006
HIV-specific CD8+ lymphocytes in semen are not associated with reduced HIV shedding.. 175. 2005
IFN-gamma-primed macrophages exhibit increased CCR2-dependent migration and altered IFN-gamma responses mediated by Stat1.. 175. 2005
Donor lymphocyte infusion induces long-term donor-specific cardiac xenograft survival through activation of recipient double-negative regulatory T cells.. 175. 2005
Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-alphabeta receptor and STAT1.. 175. 2005
Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation.. 175. 2005
Homeostatic role of interferons conferred by inhibition of IL-1-mediated inflammation and tissue destruction.. 175. 2005
Augmentation of cutaneous immune responses by ATP gamma S: purinergic agonists define a novel class of immunologic adjuvants.. 174. 2005
Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation.. 174. 2005
CD4+ T cell responses to SSX-4 in melanoma patients.. 174. 2005
Expression profiling of murine double-negative regulatory T cells suggest mechanisms for prolonged cardiac allograft survival.. 174. 2005
The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages.. 174. 2005
Cathepsin S controls MHC class II-mediated antigen presentation by epithelial cells in vivo.. 174. 2005
Tim-3+ T-bet+ tumor-specific Th1 cells colocalize with and inhibit development and growth of murine neoplasms.. 174. 2005
Langerhans cells derived from genetically modified human CD34+ hemopoietic progenitors are more potent than peptide-pulsed Langerhans cells for inducing antigen-specific CD8+ cytolytic T lymphocyte responses.. 174. 2005
TNF-alpha is a critical effector and a target for therapy in antiphospholipid antibody-induced pregnancy loss.. 174. 2005
Anti-phospholipid antibodies restore mesenteric ischemia/reperfusion-induced injury in complement receptor 2/complement receptor 1-deficient mice.. 173. 2004
Vasoactive intestinal peptide modulates Langerhans cell immune function.. 173. 2004
The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity.. 173. 2004
A mouse herpesvirus induces relapse of experimental autoimmune arthritis by infection of the inflammatory target tissue.. 173. 2004
Novel and promiscuous CTL epitopes in conserved regions of Gag targeted by individuals with early subtype C HIV type 1 infection from southern Africa.. 173. 2004
Mature human Langerhans cells derived from CD34+ hematopoietic progenitors stimulate greater cytolytic T lymphocyte activity in the absence of bioactive IL-12p70, by either single peptide presentation or cross-priming, than do dermal-interstitial or monocyte-derived dendritic cells.. 173. 2004
Molecular recognition patterns of serum anti-DNA topoisomerase I antibody in systemic sclerosis.. 173. 2004
Characterization of distinct conventional and plasmacytoid dendritic cell-committed precursors in murine bone marrow.. 173. 2004
Mechanism by which orally administered beta-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models.. 173. 2004
Role of IFN regulatory factor-1 and IL-12 in immunological resistance to pathogenesis of N-methyl-N-nitrosourea-induced T lymphoma.. 173. 2004
CTLA-4 regulates expansion and differentiation of Th1 cells following induction of peripheral T cell tolerance.. 172. 2004
IL-1beta impairs insulin-like growth factor i-induced differentiation and downstream activation signals of the insulin-like growth factor i receptor in myoblasts.. 172. 2004
IL-1beta suppresses prolonged Akt activation and expression of E2F-1 and cyclin A in breast cancer cells.. 172. 2004
Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function.. 172. 2004
Identification of an SSX-2 epitope presented by dendritic cells to circulating autologous CD4+ T cells.. 172. 2004
IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis.. 172. 2004
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells.. 172. 2004
Effect of decreasing the affinity of the class II-associated invariant chain peptide on the MHC class II peptide repertoire in the presence or absence of H-2M.. 172. 2004
Genome-wide analysis of molecular changes in IL-12-induced control of mammary carcinoma via IFN-gamma-independent mechanisms.. 172. 2004
Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells.. 172. 2004
Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL.. 172. 2004
Vaccine-induced CD4+ T cell responses to MAGE-3 protein in lung cancer patients.. 172. 2004
Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma.. 171. 2003
Transcriptional regulation of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa: dissection of key promoter elements.. 171. 2003
Cutting edge: transplantation tolerance through enhanced CTLA-4 expression.. 171. 2003
Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.. 171. 2003
Reprogramming of IL-10 activity and signaling by IFN-gamma.. 171. 2003
Novel and detrimental effects of lipopolysaccharide on in vitro generation of immature dendritic cells: involvement of mitogen-activated protein kinase p38.. 171. 2003
Murine macrophages produce secretory leukocyte protease inhibitor during clearance of apoptotic cells: implications for resolution of the inflammatory response.. 171. 2003
NF-kappa B1 p50 is required for BLyS attenuation of apoptosis but dispensable for processing of NF-kappa B2 p100 to p52 in quiescent mature B cells.. 171. 2003
Inhibition of IFN-gamma signaling by glucocorticoids.. 170. 2003
Accumulation of B lymphocytes with a naive, resting phenotype in a subset of hepatitis C patients.. 170. 2003
Role of double-negative regulatory T cells in long-term cardiac xenograft survival.. 170. 2003
Cross-presentation of HLA class I epitopes from exogenous NY-ESO-1 polypeptides by nonprofessional APCs.. 170. 2003
Critical requirement for professional APCs in eliciting T cell responses to novel fragments of histidyl-tRNA synthetase (Jo-1) in Jo-1 antibody-positive polymyositis.. 169. 2002
Cutting edge: a new tool to evaluate human pre-erythrocytic malaria vaccines: rodent parasites bearing a hybrid Plasmodium falciparum circumsporozoite protein.. 169. 2002
Defective thymocyte maturation by transgenic expression of a truncated form of the T lymphocyte adapter molecule and Fyn substrate, Sin.. 169. 2002
Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells.. 169. 2002
Rheumatoid arthritis synoviocyte survival is dependent on Stat3.. 169. 2002
Differential regulation of IL-12 and IL-10 gene expression in macrophages by the basic leucine zipper transcription factor c-Maf fibrosarcoma.. 169. 2002
TRAIL/Apo-2 ligand induces primary plasma cell apoptosis.. 169. 2002
The balance between donor T cell anergy and suppression versus lethal graft-versus-host disease is determined by host conditioning.. 169. 2002
Killer Ig-like receptor haplotype analysis by gene content: evidence for genomic diversity with a minimum of six basic framework haplotypes, each with multiple subsets.. 169. 2002
Constitutive OX40/OX40 ligand interaction induces autoimmune-like diseases.. 169. 2002
Expression of a functional eotaxin (CC chemokine ligand 11) receptor CCR3 by human dendritic cells.. 169. 2002
Functional activation of myelin-specific T cells by virus-induced molecular mimicry.. 169. 2002
T cell proliferation induced by autologous non-T cells is a response to apoptotic cells processed by dendritic cells.. 169. 2002
The CXC chemokine murine monokine induced by IFN-gamma (CXC chemokine ligand 9) is made by APCs, targets lymphocytes including activated B cells, and supports antibody responses to a bacterial pathogen in vivo.. 169. 2002
Catecholamines inhibit the antigen-presenting capability of epidermal Langerhans cells.. 168. 2002
Characterization of mouse and human B7-H3 genes.. 168. 2002
Cutting edge: activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokine-induced hemopoietic suppression in aplastic anemia.. 168. 2002
Identification of a candidate regulatory region in the human CD8 gene complex by colocalization of DNase I hypersensitive sites and matrix attachment regions which bind SATB1 and GATA-3.. 168. 2002
A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation.. 168. 2002
The bacterial peptide N-formyl-Met-Leu-Phe inhibits killing of Staphylococcus epidermidis by human neutrophils in fibrin gels.. 168. 2002
1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells.. 167. 2001
Cross-talk between IL-1 and IL-6 signaling pathways in rheumatoid arthritis synovial fibroblasts.. 167. 2001
The critical role of LIGHT, a TNF family member, in T cell development.. 167. 2001
Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis.. 167. 2001
Efficient presentation of both cytosolic and endogenous transmembrane protein antigens on MHC class II is dependent on cytoplasmic proteolysis.. 167. 2001
Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus.. 167. 2001
IFN-gamma-independent autocrine cytokine regulatory mechanism in reprogramming of macrophage responses to bacterial lipopolysaccharide.. 167. 2001
Blockade of alpha 5 beta 1 integrins reverses the inhibitory effect of tenascin on chemotaxis of human monocytes and polymorphonuclear leukocytes through three-dimensional gels of extracellular matrix proteins.. 166. 2001
Distinct autoreactive T cell responses to native and fragmented DNA topoisomerase I: influence of APC type and IL-2.. 166. 2001
Suppression of Il-12 transcription in macrophages following Fc gamma receptor ligation.. 166. 2001
Cutting edge: C3, a key component of complement activation, is not required for the development of myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis in mice.. 166. 2001
Differential modulation of stimulatory and inhibitory Fc gamma receptors on human monocytes by Th1 and Th2 cytokines.. 166. 2001
Targeting signal 1 through CD45RB synergizes with CD40 ligand blockade and promotes long term engraftment and tolerance in stringent transplant models.. 166. 2001
Genetic analyses of NFKB1 and OCA-B function: defects in B cells, serum IgM level, and antibody responses in Nfkb1-/-Oca-b-/- mice.. 165. 2000
Inhibition of IL-6 and IL-10 signaling and Stat activation by inflammatory and stress pathways.. 165. 2000
Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes.. 165. 2000
Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumor-reactive CTL.. 165. 2000
An IFN-gamma-inducible transcription factor, IFN consensus sequence binding protein (ICSBP), stimulates IL-12 p40 expression in macrophages.. 165. 2000
Analysis of soluble and cell surface factors regulating anti-DNA topoisomerase I autoantibody production demonstrates synergy between Th1 and Th2 autoreactive T cells.. 164. 2000
Competition for specific intrathymic ligands limits positive selection in a TCR transgenic model of CD4+ T cell development.. 164. 2000
The regulation of CD95 (Fas) ligand expression in primary T cells: induction of promoter activation in CD95LP-Luc transgenic mice.. 164. 2000
Cutting edge: ectopic expression of the IL-12 receptor-beta 2 in developing and committed Th2 cells does not affect the production of IL-4 or induce the production of IFN-gamma.. 164. 2000
Inhibition of IL-12 production in human monocyte-derived macrophages by TNF.. 164. 2000
Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells.. 164. 2000
Viral IL-10 gene transfer decreases inflammation and cell adhesion molecule expression in a rat model of venous thrombosis.. 164. 2000
Cutting edge: a novel function for the SLAP-130/FYB adapter protein in beta 1 integrin signaling and T lymphocyte migration.. 164. 2000
Retrovirally transduced mouse dendritic cells require CD4+ T cell help to elicit antitumor immunity: implications for the clinical use of dendritic cells.. 164. 2000
Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis.. 164. 2000
CD30 overexpression enhances negative selection in the thymus and mediates programmed cell death via a Bcl-2-sensitive pathway.. 163. 1999
Reactive oxygen intermediates enhance Fc gamma receptor signaling and amplify phagocytic capacity.. 162. 1999
Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide.. 162. 1999
Paradoxical preservation of a lipopolysaccharide response in C3H/HeJ macrophages: induction of matrix metalloproteinase-9.. 162. 1999
Postthymic development of CD28-CD8+ T cell subset: age-associated expansion and shift from memory to naive phenotype.. 162. 1999
IL-4 selectively inhibits IL-2-triggered Stat5 activation, but not proliferation, in human T cells.. 162. 1999
Extrathymic T cell differentiation in the human intestine early in life.. 161. 1998
OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40.. 161. 1998
Antibodies against IL-12 prevent superantigen-induced and spontaneous relapses of experimental autoimmune encephalomyelitis.. 161. 1998
Oleic acid increases cell surface expression and activity of CD11b on human neutrophils.. 161. 1998
SLP-76 expression is restricted to hemopoietic cells of monocyte, granulocyte, and T lymphocyte lineage and is regulated during T cell maturation and activation.. 161. 1998
Monoclonal antibody therapy of B cell lymphoma: signaling activity on tumor cells appears more important than recruitment of effectors.. 161. 1998
Extracellular signal-regulated kinase-2, but not c-Jun NH2-terminal kinase, activation correlates with surface IgM-mediated apoptosis in the WEHI 231 B cell line.. 161. 1998
A newly identified response element in the CD95 ligand promoter contributes to optimal inducibility in activated T lymphocytes.. 161. 1998
Tissue-specific up-regulation of B7-1 expression and function during the course of murine relapsing experimental autoimmune encephalomyelitis.. 161. 1998
Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10.. 160. 1998
Base-specific sequences that bias somatic hypermutation deduced by analysis of out-of-frame human IgVH genes.. 160. 1998
p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation.. 160. 1998
Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: insights into the pathophysiology of osteomyelofibrosis.. 160. 1998
The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression.. 160. 1998
Inhibition of IL-12 production by thalidomide.. 159. 1997
Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice.. 159. 1997
Three domains of SLP-76 are required for its optimal function in a T cell line.. 159. 1997
Correction of defective expression in MHC class II deficiency (bare lymphocyte syndrome) cells by retroviral transduction of CIITA.. 159. 1997
Regulation of CD95 (Fas) ligand expression by TCR-mediated signaling events.. 158. 1997
Expanded CD4+ and CD8+ T cell clones in elderly humans.. 158. 1997
Membrane IgM-induced tyrosine phosphorylation of CD19 requires a CD19 domain that mediates association with components of the B cell antigen receptor complex.. 158. 1997
Intracellular Ca2+ elevation and cyclosporin A synergistically induce TGF-beta 1-mediated apoptosis in lymphocytes.. 158. 1997
Nitric oxide, an autocrine regulator of wound fibroblast synthetic function.. 158. 1997
Sequestration of p56(lck) by gp120, a model for TCR desensitization.. 158. 1997
Surface expression of hemopoietic cell phosphatase fails to complement CD45 deficiency and inhibits TCR-mediated signal transduction in a Jurkat T cell clone.. 158. 1997
Highly restricted TCR-alpha beta usage by autoreactive human T cell clones specific for DNA topoisomerase I: recognition of an immunodominant epitope.. 158. 1997
Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice.. 157. 1996
CD40 ligation results in protein kinase C-independent activation of ERK and JNK in resting murine splenic B cells.. 157. 1996
Characterization of an Ig VH idiotope that results in specific homophilic binding and increased avidity for antigen.. 157. 1996
Inhibition of transcription factor Stat1 activity in mononuclear cell cultures and T cells by the cyclic AMP signaling pathway.. 157. 1996
The signaling activity of murine CD19 is regulated during cell development.. 157. 1996
Phenotype and function of CD4+ T cells in mice lacking invariant chain.. 156. 1996
Protection against lethal Escherichia coli bacteremia in baboons (Papio anubis) by pretreatment with a 55-kDa TNF receptor (CD120a)-Ig fusion protein, Ro 45-2081.. 156. 1996
Variation in HLA-DM expression influences conversion of MHC class II alpha beta:class II-associated invariant chain peptide complexes to mature peptide-bound class II alpha beta dimers in a normal B cell line.. 156. 1996
IFN-gamma induces a p91/Stat1 alpha-related transcription factor with distinct activation and binding properties.. 155. 1995
T and B cell collaboration is essential for the autoantibody response to DNA topoisomerase I in systemic sclerosis.. 155. 1995
Expansion of immunostimulatory dendritic cells among the myeloid progeny of human CD34+ bone marrow precursors cultured with c-kit ligand, granulocyte-macrophage colony-stimulating factor, and TNF-alpha.. 154. 1995
Requirement for peptide in alloreactive CD4+ T cell recognition of class II MHC molecules.. 154. 1995
Regulation by CD45 of the tyrosine phosphorylation of high affinity IgE receptor beta- and gamma-chains.. 154. 1995
Vesicle membrane association of nitric oxide synthase in primary mouse macrophages.. 154. 1995
Influence of IL-1 receptor blockade on the human response to endotoxemia.. 154. 1995
Reactivity of autologous CD4+ T lymphocytes against human melanoma. Evidence for a shared melanoma antigen presented by HLA-DR15.. 154. 1995
Murine VCAM-1. Molecular cloning, mapping, and analysis of a truncated form.. 153. 1994
Simultaneous activation of Ig and Oct-2 synthesis and reduction of surface MHC class II expression by IL-6.. 153. 1994
Idiotype- and anti-idiotype-reactive T lymphocytes in myasthenia gravis. Evidence for the involvement of different subpopulations of T helper lymphocytes.. 153. 1994
Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats.. 153. 1994
Staphylococcal protein A induces biased production of Ig by VH3-expressing B lymphocytes.. 153. 1994
Severe combined immunodeficient mice engrafted with human splenocytes have functional human T cells and reject human allografts.. 153. 1994
Effect of aging on murine macrophages. Diminished response to IFN-gamma for enhanced oxidative metabolism.. 153. 1994
Glycosyl phosphatidylinositol membrane anchor is not required for T cell activation through CD73.. 153. 1994
Role and effect of TNF-alpha in experimental visceral leishmaniasis.. 153. 1994
Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patients.. 152. 1994
Inactivation of nitric oxide synthase after prolonged incubation of mouse macrophages with IFN-gamma and bacterial lipopolysaccharide.. 152. 1994
Binding of C3b and C4b by the CR1-like site in murine CR1.. 152. 1994
Nucleotide sequence analysis of natural and combinatorial anti-PDC-E2 antibodies in patients with primary biliary cirrhosis. Recapitulating immune selection with molecular biology.. 152. 1994
T-BAM/CD40-L on helper T lymphocytes augments lymphokine-induced B cell Ig isotype switch recombination and rescues B cells from programmed cell death.. 152. 1994
Relationship between multiple biologic effects of rapamycin and the inhibition of pp70S6 protein kinase activity. Analysis in mutant clones of a T cell lymphoma.. 152. 1994
CD40 molecules induce down-modulation and endocytosis of T cell surface T cell-B cell activating molecule/CD40-L. Potential role in regulating helper effector function.. 152. 1994
Naturally processed cytokine-derived peptide bound to HLA-class II molecules.. 151. 1993
Taxol shares the ability of bacterial lipopolysaccharide to induce tyrosine phosphorylation of microtubule-associated protein kinase.. 151. 1993
Analysis of Ig H chain gene segment utilization in human fetal liver. Revisiting the "proximal utilization hypothesis".. 151. 1993
Human mononuclear phagocytes express adenosine A1 receptors. A novel mechanism for differential regulation of Fc gamma receptor function.. 151. 1993
Localization of an immunologically functional region of the streptococcal superantigen pepsin-extracted fragment of type 5 M protein.. 151. 1993
Role and effect of IL-2 in experimental visceral leishmaniasis.. 151. 1993
Traces of bacterial lipopolysaccharide suppress IFN-gamma-induced nitric oxide synthase gene expression in primary mouse macrophages.. 151. 1993
Dissection of the function of HLA class II and costimulation in B cell-mediated and toxic shock syndrome toxin-1-induced T cell proliferation.. 150. 1993
Macrophage-dependent candidacidal mechanisms in the murine system. Comparison of murine Kupffer cell and peritoneal macrophage candidacidal mechanisms.. 150. 1993
Growth inhibition of a B cell clone mediated by ligation of IL-4 receptors or membrane IgM.. 150. 1993
Molecular interactions mediating T-B lymphocyte collaboration in human lymphoid follicles. Roles of T cell-B-cell-activating molecule (5c8 antigen) and CD40 in contact-dependent help.. 149. 1992
Idiotypic and antiidiotypic T and B lymphocytes in myasthenia gravis.. 149. 1992
VH restriction among human cold agglutinins. The VH4-21 gene segment is required to encode anti-I and anti-i specificities.. 149. 1992
Mapping of the rabbit MHC reveals that class I genes are adjacent to the DR subregion and defines an insertion/deletion-related polymorphism in the class II region.. 149. 1992
Restoration of T cell receptor-mediated signal transduction by transfection of CD45 cDNA into a CD45-deficient variant of the Jurkat T cell line.. 149. 1992
Monoclonal antibody detection of a major self peptide. MHC class II complex.. 148. 1992
Clonally related IgM rheumatoid factors undergo affinity maturation in the rheumatoid synovial tissue.. 148. 1992
Interactions of bacterial lipopolysaccharide with microtubule proteins.. 148. 1992
Macrophage inflammatory protein 1 modulates macrophage function.. 148. 1992
Cellular mechanisms of the antitumor activity of recombinant IL-6 in mice.. 148. 1992
Acquired resistance and granuloma formation in experimental visceral leishmaniasis. Differential T cell and lymphokine roles in initial versus established immunity.. 148. 1992
Effects of intravenous IL-8 administration in nonhuman primates.. 148. 1992
Anti-CD3-stimulated T cells induce the production of multiple Ig H chain isotypes by individual human peripheral B lymphocytes.. 148. 1992
Chimeric and humanized antibodies with specificity for the CD33 antigen.. 148. 1992
The CD19 complex of B lymphocytes. Activation of phospholipase C by a protein tyrosine kinase-dependent pathway that can be enhanced by the membrane IgM complex.. 147. 1991
Subpopulations of B cells in germinal centers. III. HJ6, a monoclonal antibody, binds globoside and a subpopulation of germinal center B cells.. 147. 1991
Interaction of iC3b with recombinant isotypic and chimeric forms of CR2.. 147. 1991
T helper cell-dependent, microbial superantigen-induced murine B cell activation: polyclonal and antigen-specific antibody responses.. 147. 1991
Soluble IL-2 receptor as an agent of serum-mediated suppression in human visceral leishmaniasis.. 147. 1991
Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype.. 146. 1991
IL-8 in septic shock, endotoxemia, and after IL-1 administration.. 146. 1991
Fc gamma receptor III induces actin polymerization in human neutrophils and primes phagocytosis mediated by Fc gamma receptor II.. 146. 1991
Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory.. 145. 1990
Homophilic binding of mouse monoclonal antibodies against GD3 ganglioside.. 145. 1990
Macrophage deactivating factor and transforming growth factors-beta 1 -beta 2 and -beta 3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-gamma.. 145. 1990
Fc gamma RIII expressed on cultured monocytes is a N-glycosylated transmembrane protein distinct from Fc gamma RIII expressed on natural killer cells.. 144. 1990
Heteroconjugate antibody-directed killing of autologous human renal carcinoma cells by in vitro-activated lymphocytes.. 144. 1990
Cloning and sequence analysis of the VH and VL regions of an anti-myelin/DNA antibody from a patient with peripheral neuropathy and chronic lymphocytic leukemia.. 144. 1990
Nucleotide sequence of a human monoclonal anti-idiotypic antibody specific for a rabies virus-neutralizing monoclonal idiotypic antibody reveals extensive somatic variability suggestive of an antigen-driven immune response.. 144. 1990
Immune stimulatory properties of metalloporphyrins.. 143. 1989
Polymeric C3dg primes human B lymphocytes for proliferation induced by anti-IgM.. 143. 1989
Heterogeneity of protein kinase C isoenzyme gene expression in human T cell lines. Protein kinase C-beta is not required for several T cell functions.. 143. 1989
Human Fc gamma RIII (CD16). Isoforms with distinct allelic expression, extracellular domains, and membrane linkages on polymorphonuclear and natural killer cells.. 143. 1989
Transferrin receptor synthesis is an early event in B cell activation.. 143. 1989
Adenosine regulates the respiratory burst of cytokine-triggered human neutrophils adherent to biologic surfaces.. 143. 1989
Antibodies against ganglioside GT3 in the sera of patients with type I diabetes mellitus.. 142. 1989
Comparison of transforming growth factor-beta and a macrophage- deactivating polypeptide from tumor cells. Differences in antigenicity and mechanism of action.. 142. 1989
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.. 141. 1988
Synergistic interaction between complement receptor type 2 and membrane IgM on B lymphocytes.. 141. 1988
Selective synthesis of mRNA and proteins by human peripheral blood neutrophils.. 140. 1988
IFN-gamma-activated human alveolar macrophages inhibit the intracellular multiplication of Legionella pneumophila.. 140. 1988
Generation of lipid neutrophil chemoattractant by irradiated bovine aortic endothelial cells.. 140. 1988
Direct human T helper cell-induced B cell activation is not mediated by inositol lipid hydrolysis.. 140. 1988
Induction of glial cell MHC antigen expression in neurotropic coronavirus infections. Characterization of the H-2-inducing soluble factor elaborated by infected brain cells.. 140. 1988
Molecular genotypes of the human T cell receptor gamma-chain.. 140. 1988
In vitro generated human monoclonal trinitrophenyl-specific B cell lines. Evidence that human and murine anti-trinitrophenyl monoclonal antibodies cross-react with Escherichia coli beta-galactosidase.. 139. 1987
Stimulation of T lymphocyte proliferation by monoclonal antibodies against GD3 ganglioside.. 139. 1987
Trace levels of bacterial lipopolysaccharide prevent interferon-gamma or tumor necrosis factor-alpha from enhancing mouse peritoneal macrophage respiratory burst capacity.. 139. 1987
Expansion of the complement receptor gene family. Identification in the mouse of two new genes related to the CR1 and CR2 gene family.. 138. 1987
M241 (CD1) expression on B lymphocytes.. 138. 1987
Deficiency of the C3b/C4b receptor (CR1) of erythrocytes in systemic lupus erythematosus: analysis of the stability of the defect and of a restriction fragment length polymorphism of the CR1 gene.. 138. 1987
In vitro and in vivo activation of human mononuclear phagocytes by interferon-gamma. Studies with normal and AIDS monocytes.. 138. 1987
Experimental visceral leishmaniasis: production of interleukin 2 and interferon-gamma, tissue immune reaction, and response to treatment with interleukin 2 and interferon-gamma.. 138. 1987
A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.. 138. 1987
Cellular distribution of complement receptor type 4 (CR4): expression on human platelets.. 138. 1987
Differential interaction of the C3b/C4b receptor and MHC class I with the cytoskeleton of human neutrophils.. 137. 1986
Effect of recombinant interferon-gamma on hydrogen peroxide-releasing capacity of monocyte-derived macrophages from patients with lepromatous leprosy.. 137. 1986
Phagocytosis of concanavalin A-treated erythrocytes is mediated by the Fc gamma receptor.. 137. 1986
Anti-tumor properties of lymphocytes activated by the oxidizing mitogens.. 136. 1986
Altered phagocytosis by monocytes from HLA-DR2 and DR3-positive healthy adults is Fc gamma receptor specific.. 136. 1986
Suppression of natural killer cell activity by human seminal plasma in vitro: identification of 19-OH-PGE as the suppressor factor.. 136. 1986
Decreased natural killer activity in thalassemia major: a possible consequence of iron overload.. 136. 1986
Characterization of the antigenic determinants and host components in immune complexes from patients with secondary syphilis.. 136. 1986
Cell mediated immunity in American cutaneous and mucosal leishmaniasis.. 135. 1985
Monoclonal antibody OKM5 inhibits the in vitro binding of Plasmodium falciparum-infected erythrocytes to monocytes, endothelial, and C32 melanoma cells.. 135. 1985
Synergy between B cell differentiation factors and interleukin 2, using a monoclonal system.. 135. 1985
Activation of tissue macrophages from AIDS patients: in vitro response of AIDS alveolar macrophages to lymphokines and interferon-gamma.. 135. 1985
Requirements for T cell activation by OKT3 monoclonal antibody: role of modulation of T3 molecules and interleukin 1.. 135. 1985
Cloned allospecific human helper T cell lines induce an MHC-restricted proliferative response by resting B cells.. 135. 1985
Long-term culture of human bone marrow macrophages: macrophage development is associated with the production of granulomonopoietic enhancing activity (GM-EA).. 135. 1985
Human B lymphoblastoid cell lines provide an interleukin 1-like signal for mitogen-treated T lymphocytes via direct cell contact.. 134. 1985
In vitro delayed hypersensitivity granuloma formation: development of an antigen-coated bead model.. 134. 1985
p65: A C3b-binding protein on murine cells that shares antigenic determinants with the human C3b receptor (CR1) and is distinct from murine C3b receptor.. 134. 1985
Characterization of a soluble form of the C3b/C4b receptor (CR1) in human plasma.. 134. 1985
Neutrophils express a receptor for iC3b, C3dg, and C3d that is distinct from CR1, CR2, and CR3.. 134. 1985
Production and response to interleukin 2 in vitro and in vivo after bone marrow transplantation in mice.. 134. 1985
Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma.. 134. 1985
PMA induces the ligand-independent internalization of CR1 on human neutrophils.. 134. 1985
Suppression of interleukin 2 receptor acquisition by monoclonal antibodies recognizing the 50 KD protein associated with the sheep erythrocyte receptor on human T lymphocytes.. 134. 1985
The four biochemically distinct species of human interleukin 1 all exhibit similar biologic activities.. 134. 1985
Normal function of CR1 on affected erythrocytes of patients with paroxysmal nocturnal hemoglobinuria.. 134. 1985
Defective mononuclear phagocyte function in systemic lupus erythematosus: dissociation of Fc receptor-ligand binding and internalization.. 133. 1984
Specificity of human IgM M-proteins that bind to myelin-associated glycoprotein: peptide mapping, deglycosylation, and competitive binding studies.. 133. 1984
An antigen characteristic of hairy cell leukemia cells is expressed on certain activated B cells.. 133. 1984
Preparation and characterization of monoclonal antibodies recognizing three distinct differentiation antigens (BL1, BL2, BL3) on human B lymphocytes.. 133. 1984
A membrane antigen (HC1) selectively present on hairy cell leukemia cells, endothelial cells, and epidermal basal cells.. 132. 1984
Altered surface distribution of both C3b receptors and Fc receptors on neutrophils induced by anti-C3b receptor or aggregated IgG.. 132. 1984
Inhibition of the function of activated properdin by squid chondroitin sulfate E glycosaminoglycan and murine bone marrow-derived mast cell chondroitin sulfate E proteoglycan.. 132. 1984
Monoclonal anti-human monocyte antibodies OKM1 and OKM5 possess distinctive tissue distributions including differential reactivity with vascular endothelium.. 132. 1984
Establishment of cell lines from somatic cell hybrids between human monocytes and mouse myeloma cells.. 132. 1984
Modulation of mononuclear phagocyte function by intravenous gamma-globulin.. 132. 1984
Suppression of cell-mediated immune responses after total lymphoid irradiation (TLI). I. Characterization of suppressor cells of the mixed lymphocyte reaction.. 132. 1984
Characterization of human T lymphocytes that express the C3b receptor.. 131. 1983
Suppression of macrophage antimicrobial activity by a tumor cell product.. 131. 1983
Interleukin 2-dependent natural killer (NK) cell lines from patients with primary T cell immunodeficiencies.. 130. 1983
Specificity and idiotype of M-proteins that react with MAG in patients with neuropathy.. 130. 1983
Expression of C3b receptors on human be cells and myelomonocytic cells but not natural killer cells.. 130. 1983
Generation of C3a anaphylatoxin from human C3 by human mast cell tryptase.. 130. 1983
Increased expression of C3b receptors on polymorphonuclear leukocytes induced by chemotactic factors and by purification procedures.. 130. 1983
Abnormal T lymphocyte subpopulations in patients with B cell chronic lymphocytic leukemia: an analysis by monoclonal antibodies.. 129. 1982
Role of oxygen in T cell-mediated cytolysis.. 129. 1982
Isolation of a human erythrocyte membrane glycoprotein with decay-accelerating activity for C3 convertases of the complement system.. 129. 1982
A phorbol ester (TPA) can replace macrophages in human lymphocyte cultures stimulated with a mitogen but not with an antigen.. 128. 1982
Antibody restores human alternative complement pathway activation by mouse erythrocytes rendered functionally deficient by pretreatment with pronase.. 128. 1982
OT-CLL: a human T cell chronic lymphocytic leukemia that produces IL 2 in high titer.. 128. 1982
Expression of Fc mu receptors by human T lymphocytes: effects of enzymes, metabolic inhibitors, and X-irradiation.. 127. 1981
Hydrogen peroxide and cytolytic factor can interact synergistically in effecting cytolysis of neoplastic targets.. 127. 1981
The fixation of C3b to pneumococcal cell wall polymers as a result of activation of the alternative complement pathway.. 127. 1981
IgG on mouse erythrocytes augments activation of the human alternative complement pathway by enhancing deposition of C3b.. 126. 1981
Human medullary and cortical thymocytes are distinguishable according to the presence or absence of cytochemically demonstrable acid alpha-naphthyl acetate esterase (ANAE) activity.. 125. 1980
Defective spontaneous and antibody-dependent cytotoxicity mediated by E-rosette-positive and E-rosette-negative cells in untreated patients with chronic lymphocytic leukemia: augmentation by in vitro treatment with interferon.. 125. 1980
Activation of C3 via the alternative complement pathway results in fixation of C3b to the pneumococcal cell wall.. 124. 1980
Inhibition of the alternative pathway of human complement in vitro by a natural microbial product, complestatin.. 124. 1980
Characterization of the IgE receptor isolated from human basophils.. 123. 1979
Increased prostaglandin synthesis by macrophages from tumor-bearing mice.. 123. 1979
Immune suppression in vivo with antigen-modified syngeneic cells. II. T cell-mediated nonresponsiveness to fowl gamma-globulin.. 122. 1979
Action of the C3b-inactivator on the cell-bound C3b.. 122. 1979
Three suppressor systems in human blood that modulate lymphoproliferation.. 122. 1979
Human alternative complement pathway: membrane-associated sialic acid regulates the competition between B and beta1 H for cell-bound C3b.. 122. 1979
H-2 control of tolerance induction to L-glutamic acid, L-lysine-containing polymers.. 121. 1978
Inhibition of the alternative pathway of complement by gold sodium thiomalate in vitro.. 120. 1978
Heterogeneity, polypeptide chain composition and antigenic reactivity of C3 nephritic factor.. 120. 1978
Opsonin-independent phagocytosis of activators of the alternative complement pathway by human monocytes.. 120. 1978
The modulation of the alternative pathway of complement in C2-deficient human serum by changes in concentration of the component and control proteins.. 120. 1978
Activation of the alternative complement pathway by pneumococcal cell wall teichoic acid.. 120. 1978
Modulation of Fc-mediated phagocytosis by cyclic AMP and insulin in a macrophage-like cell line.. 119. 1977
Purification of C3b inactivator and demonstration of its two polypeptide chain structure.. 119. 1977
Development of a hemolytic plaque assay for glutamic acid, lysine-containing polypeptides: demonstration that nonresponder mice produce antibodies to these peptides when conjugated to an immunogenic carrier.. 119. 1977
The incorporation of C3 nephritic factor (C3NeF) into a stabilized C3 convertase, C3bBb(C3NeF), and its release after decay of convertase function.. 119. 1977
Cell-mediated immune responses in patients with recurrent Herpes Simplex infections. II. Infection-associated deficiency of lymphokine production in patients with recurrent herpes labialis or herpes progenitalis.. 118. 1977
Cell-mediated immune responses in recurrent herpesvirus infections. I. Lymphocyte proliferation assay.. 118. 1977
Activation of the alternative pathway by pneumococcal cell walls.. 118. 1977
Reversal of cell surface abnormalities of T lymphocytes in hodgkin's disease after in vitro incubation in fetal sera.. 117. 1976
C3 requirements for formation of alternative pathway C5 convertase.. 117. 1976
Isolation of alternative pathway C3 convertase containing uncleaved B and formed in the presence of C3 nephritic factor (C3neF).. 116. 1976
C3 nephritic factor (C3NeF): stabilization of fluid phase and cell-bound alternative pathway convertase.. 116. 1976
Initiation of C3 cleavage in the alternative complement pathway.. 115. 1975
The identification of HL-A antigens on fresh and cultured human endothelial cells.. 115. 1975
Serum proteins involved in decay and regeneration of cobra venom factor-dependent complement activation.. 111. 1973
Genetic control of immune response toward the loop region of lysozyme.. 111. 1973
The specificity and cross-reactivity of antisynaptosome antibodies as determined by sequential adsorption analysis.. 107. 1971
The biologic half-life of brain-localized antisynapse radioantibodies.. 104. 1970
Correlation of immunologic and structural heterogeneity of Bence Jones proteins.. 97. 1966
Subtypes of Bence-Jones proteins.. 95. 1965
Multiple roles of CD4 and CD8 in T cell activation.. 185. 2010
Immune Cell-Stromal Circuitry in Lupus Photosensitivity. 2021
Type I interferon in the pathogenesis of lupus. 2014
Characterization of the nonphagocytic adherent cell from the peritoneal cavity of normal and BCG-treated mice. 1977
The Common Key to Class-Switch Recombination and Somatic Hypermutation: Discovery of AID and Its Role in Antibody Gene Diversification. 2018
Pillars Article: Foxp3 Programs the Development and Function of CD4+CD25+ Regulatory T Cells. Nat. Immunol. 2003. 4: 330-336. 2017
Pillars Article: Sequence Analysis of Peptides Bound to MHC Class II Molecules. Nature. 1991. 353: 622-627. 2016
Pillars Article: CD19: Lowering the threshold for antigen receptor stimulation of B lymphocytes. Science, 1992. 256: 105-107. 2010

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