Lewis, Jason S.

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uPAR Immuno-PET in Pancreatic Cancer, Aging, and Chemotherapy-Induced Senescence. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024 Academic Article GET IT
Radiotherapy and theranostics: a Lancet Oncology Commission. The Lancet. Oncology. 2024 Review GET IT
[⁸⁹Zr]ZrCl₄ for direct radiolabeling of DOTA-based precursors. Nuclear medicine and biology. 2024 Academic Article GET IT
⁸⁹Zr-immunoPET-guided selection of a CD33xIL15 fusion protein optimized for antitumor immune cell activation and in vivo tumour retention in acute myeloid leukaemia. European journal of nuclear medicine and molecular imaging. 2024 Academic Article GET IT
Examination of the PET in vivo generator ¹³⁴Ce as a theranostic match for ²²⁵Ac. European journal of nuclear medicine and molecular imaging. 2024 Academic Article GET IT
Imaging with [⁸⁹Zr]Zr-DFO-SC16.56 anti-DLL3 antibody in patients with high-grade neuroendocrine tumours of the lung and prostate: a phase 1/2, first-in-human trial. The Lancet. Oncology. 2024 Academic Article GET IT
Times cited: 3
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer. Nature medicine. 2024 Academic Article GET IT
Times cited: 5
Production and regulatory issues for theranostics. The Lancet. Oncology. 2024 Review GET IT
Times cited: 2
Recent advances and impending challenges for the radiopharmaceutical sciences in oncology. The Lancet. Oncology. 2024 Review GET IT
Trends in nuclear medicine and the radiopharmaceutical sciences in oncology: workforce challenges and training in the age of theranostics. The Lancet. Oncology. 2024 Review GET IT
CEACAM5-Targeted Immuno-PET in Androgen Receptor-Negative Prostate Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024 Academic Article GET IT
Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness. Cell metabolism. 2024 Academic Article GET IT
¹⁸F-BMS-986229 PET to Assess Programmed-Death Ligand 1 Status in Gastroesophageal Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024 Academic Article GET IT
Radiopharmaceuticals for Cancer Diagnosis and Therapy: New Targets, New Therapies-Alpha-Emitters, Novel Targets. Cancer journal (Sudbury, Mass.). 2024 Review GET IT
Exploring the PET in vivo generator ¹³⁴Ce as a theranostic match for ²²⁵Ac. 2024 GET IT
Na_V1.7 targeted fluorescence imaging agents for nerve identification during intraoperative procedures. 2024 GET IT
Interrogating the Theranostic Capacity of a MUC16-Targeted Antibody for Ovarian Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024 Academic Article GET IT
First-in-Human Evaluation of Site-Specifically Labeled ⁸⁹Zr-Pertuzumab in Patients with HER2-Positive Breast Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024 Academic Article GET IT
Times cited: 8
First-in-human imaging with [⁸⁹Zr]Zr-DFO-SC16.56 anti-DLL3 antibody in patients with high-grade neuroendocrine tumors of the lung and prostate. 2024 GET IT
Correction to "Shifting the Antibody-Drug Conjugate Paradigm: A Trastuzumab-Gold-Based Conjugate Demonstrates High Efficacy against Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Mouse Model". 2024 GET IT
Methods for the Production of Radiolabeled Bioagents for ImmunoPET. Methods in molecular biology (Clifton, N.J.). 2024 Review GET IT
Shifting the Antibody-Drug Conjugate Paradigm: A Trastuzumab-Gold-Based Conjugate Demonstrates High Efficacy against Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Mouse Model. ACS pharmacology & translational science. 2023 Academic Article GET IT
Times cited: 2
Development of immunoliposomes containing cytotoxic gold payloads against HER2-positive breast cancers. RSC medicinal chemistry. 2023 Academic Article GET IT
Times cited: 1
²¹²Pb-Pretargeted Theranostics for Pancreatic Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2023 Academic Article GET IT
Click Chemistry and Radiochemistry: An Update. Bioconjugate chemistry. 2023 Review GET IT
Times cited: 21
Determinants of Survival with Combined HER2 and PD-1 Blockade in Metastatic Esophagogastric Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Times cited: 8
PET and Optical Imaging of Caveolin-1 in Gastric Tumors. ACS omega. 2023 Academic Article GET IT
Times cited: 2
Ambient Light Resistant Shortwave Infrared Fluorescence Imaging for Preclinical Tumor Delineation via the pH Low-Insertion Peptide Conjugated to Indocyanine Green. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2023 Academic Article GET IT
Times cited: 2
Immuno-PET Detects Antibody-Drug Potency on Coadministration with Statins. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2023 Academic Article GET IT
Times cited: 7
Development and Validation of Nerve-Targeted Bacteriochlorin Sensors. Journal of the American Chemical Society. 2023 Academic Article GET IT
Times cited: 1
Click chemistry: a transformative technology in nuclear medicine. Nature protocols. 2023 Review GET IT
⁸⁹Zr-DFO-Isatuximab for CD38-Targeted ImmunoPET Imaging of Multiple Myeloma and Lymphomas. ACS omega. 2023 Academic Article GET IT
Times cited: 4
Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer. Nature cancer. 2023 Academic Article GET IT
Times cited: 46
Statins enhance the efficacy of HER2-targeting radioligand therapy in drug-resistant gastric cancers. Proceedings of the National Academy of Sciences of the United States of America. 2023 Academic Article GET IT
Times cited: 9
Sc-HOPO: A Potential Construct for Use in Radioscandium-Based Radiopharmaceuticals. Inorganic chemistry. 2023 Academic Article GET IT
Times cited: 8
Radiances of Cerenkov-Emitting Isotopes on the IVIS. 2023 GET IT
Click Here for Better Chemistry. The New England journal of medicine. 2022 Academic Article GET IT
Times cited: 8
Noninvasive Assessment of Human Epidermal Growth Factor Receptor 2 (HER2) in Esophagogastric Cancer Using ⁸⁹Zr-Trastuzumab PET: A Pilot Study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2022 Academic Article GET IT
Times cited: 12
Phase 1 study of intraventricular ¹³¹I-omburtamab targeting B7H3 (CD276)-expressing CNS malignancies. Journal of hematology & oncology. 2022 Academic Article GET IT
Times cited: 25
Refined Chelator Spacer Moieties Ameliorate the Pharmacokinetics of PSMA-617. Frontiers in chemistry. 2022 Academic Article GET IT
Times cited: 1
Delta-like ligand 3-targeted radioimmunotherapy for neuroendocrine prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 2022 Academic Article GET IT
Times cited: 22
Radiotheranostics in oncology: current challenges and emerging opportunities. Nature reviews. Clinical oncology. 2022 Review GET IT
Times cited: 43
Pretargeted PET of Osteodestructive Lesions in Dogs. Molecular pharmaceutics. 2022 Academic Article GET IT
Times cited: 12
PET Imaging of Acidic Tumor Environment With ⁸⁹Zr-labeled pHLIP Probes. Frontiers in oncology. 2022 Academic Article GET IT
Times cited: 12
Caveolin-1 temporal modulation enhances antibody drug efficacy in heterogeneous gastric cancer. Nature communications. 2022 Academic Article GET IT
Times cited: 19
Noninvasive Imaging of CD4+ T Cells in Humanized Mice. Molecular cancer therapeutics. 2022 Academic Article GET IT
Times cited: 4
Radioimmunotherapy Targeting Delta-like Ligand 3 in Small Cell Lung Cancer Exhibits Antitumor Efficacy with Low Toxicity. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Times cited: 27
ImmunoPET of Ovarian and Pancreatic Cancer with AR9.6, a Novel MUC16-Targeted Therapeutic Antibody. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Times cited: 23
EGFR-Targeted ImmunoPET of UMUC3 Orthotopic Bladder Tumors. Molecular imaging and biology. 2022 Academic Article GET IT
Times cited: 6
Molecular Imaging of Neuroendocrine Prostate Cancer by Targeting Delta-Like Ligand 3. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2022 Academic Article GET IT
Times cited: 22
Imaging of Cancer γ-Secretase Activity Using an Inhibitor-Based PET Probe. Clinical cancer research : an official journal of the American Association for Cancer Research. 2021 Academic Article GET IT
Times cited: 7
Novel Tracers and Radionuclides in PET Imaging. Radiologic clinics of North America. 2021 Review GET IT
Times cited: 4
Influence of Fc Modifications and IgG Subclass on Biodistribution of Humanized Antibodies Targeting L1CAM. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2021 Academic Article GET IT
ERK Inhibition Improves Anti-PD-L1 Immune Checkpoint Blockade in Preclinical Pancreatic Ductal Adenocarcinoma. Molecular cancer therapeutics. 2021 Academic Article GET IT
Times cited: 12
Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system. Nature communications. 2021 Academic Article GET IT
Times cited: 24
State-of-the-Art of Radiometal-based Bioconjugates for Molecular Imaging and Radiotherapy. Bioconjugate chemistry. 2021 Editorial Article GET IT
Tim-4⁺ cavity-resident macrophages impair anti-tumor CD8⁺ T cell immunity. Cancer cell. 2021 Academic Article GET IT
Times cited: 115
Recent Advances in Radiometals for Combined Imaging and Therapy in Cancer. ChemMedChem. 2021 Review GET IT
Times cited: 32
Reply: Potential Use of Radiolabeled Antibodies for Imaging and Treatment of COVID-19. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2021 Letter GET IT
Synthesis and Comparative In Vivo Evaluation of Site-Specifically Labeled Radioimmunoconjugates for DLL3-Targeted ImmunoPET. Bioconjugate chemistry. 2021 Academic Article GET IT
Times cited: 10
Exploiting the MUC5AC Antigen for Noninvasive Identification of Pancreatic Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2021 Academic Article GET IT
Times cited: 4
Technical Note: Patient-morphed mesh-type phantoms to support personalized nuclear medicine dosimetry - a proof of concept study. Medical physics. 2021 Academic Article GET IT
Times cited: 2
Medical imaging and nuclear medicine: a Lancet Oncology Commission. The Lancet. Oncology. 2021 Review GET IT
Times cited: 168
Applications of nuclear-based imaging in gene and cell therapy: probe considerations. Molecular therapy oncolytics. 2021 Academic Article GET IT
Times cited: 15
A simple strategy to reduce the salivary gland and kidney uptake of PSMA-targeting small molecule radiopharmaceuticals. European journal of nuclear medicine and molecular imaging. 2021 Academic Article GET IT
Times cited: 34
Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors with [⁶⁴Cu]Cu-NOTA-anti-CD8 PET. Clinical cancer research : an official journal of the American Association for Cancer Research. 2021 Academic Article GET IT
Times cited: 29
Bimodal Imaging of Mouse Peripheral Nerves with Chlorin Tracers. Molecular pharmaceutics. 2021 Academic Article GET IT
Times cited: 7
Predicting CAR-T cell Immunotherapy Success through ImmunoPET. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Comment GET IT
Times cited: 5
The Future of Nuclear Medicine, Molecular Imaging, and Theranostics. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020 Review GET IT
Times cited: 12
Polyazamacrocycle Ligands Facilitate ⁸⁹Zr Radiochemistry and Yield ⁸⁹Zr Complexes with Remarkable Stability. Inorganic chemistry. 2020 Academic Article GET IT
Times cited: 18
Imaging Early-Stage Metastases Using an ¹⁸F-Labeled VEGFR-1-Specific Single Chain VEGF Mutant. Molecular imaging and biology. 2020 Academic Article GET IT
Times cited: 6
Comparison of Methods for Surface Modification of Barium Titanate Nanoparticles for Aqueous Dispersibility: Toward Biomedical Utilization of Perovskite Oxides. ACS applied materials & interfaces. 2020 Academic Article GET IT
Times cited: 26
B7H3-Directed Intraperitoneal Radioimmunotherapy With Radioiodinated Omburtamab for Desmoplastic Small Round Cell Tumor and Other Peritoneal Tumors: Results of a Phase I Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2020 Academic Article GET IT
Times cited: 46
pHLIP ICG for delineation of tumors and blood flow during fluorescence-guided surgery. Scientific reports. 2020 Academic Article GET IT
Times cited: 25
Harnessing ⁶⁴Cu/⁶⁷Cu for a theranostic approach to pretargeted radioimmunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 2020 Academic Article GET IT
Times cited: 75
Leveraging synthetic chlorins for bio-imaging applications. Chemical communications (Cambridge, England). 2020 Academic Article GET IT
Times cited: 7
Antibody-Targeted Imaging of Gastric Cancer. Molecules (Basel, Switzerland). 2020 Review GET IT
Times cited: 8
Aromatic carbohydrate amphiphile disrupts cancer spheroids and prevents relapse. Nanoscale. 2020 Academic Article GET IT
Times cited: 11
Acute Statin Treatment Improves Antibody Accumulation in EGFR- and PSMA-Expressing Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Times cited: 23
ImmunoPET Imaging of Pancreatic Tumors with ⁸⁹Zr-Labeled Gold Nanoparticle-Antibody Conjugates. Molecular imaging and biology. 2020 Academic Article GET IT
Times cited: 21
A High-Denticity Chelator Based on Desferrioxamine for Enhanced Coordination of Zirconium-89. Inorganic chemistry. 2020 Academic Article GET IT
Times cited: 24
Head-to-Head Evaluation of ¹⁸F-FES and ¹⁸F-FDG PET/CT in Metastatic Invasive Lobular Breast Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020 Academic Article GET IT
Times cited: 87
Oncology-Inspired Treatment Options for COVID-19. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020 Academic Article GET IT
Times cited: 13
A Molecularly Targeted Intraoperative Near-Infrared Fluorescence Imaging Agent for High-Grade Serous Ovarian Cancer. Molecular pharmaceutics. 2020 Academic Article GET IT
Times cited: 16
Immuno-PET Detects Changes in Multi-RTK Tumor Cell Expression Levels in Response to Targeted Kinase Inhibition. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020 Academic Article GET IT
Times cited: 4
Identification of HER2-Positive Metastases in Patients with HER2-Negative Primary Breast Cancer by Using HER2-targeted ⁸⁹Zr-Pertuzumab PET/CT. Radiology. 2020 Academic Article GET IT
Times cited: 45
Fluorescence labeling of a Na_V1.7-targeted peptide for near-infrared nerve visualization. EJNMMI research. 2020 Academic Article GET IT
Times cited: 13
Comparison of ⁶⁸Ga-DOTA-JR11 PET/CT with dosimetric ¹⁷⁷Lu-satoreotide tetraxetan (¹⁷⁷Lu-DOTA-JR11) SPECT/CT in patients with metastatic neuroendocrine tumors undergoing peptide receptor radionuclide therapy. European journal of nuclear medicine and molecular imaging. 2020 Academic Article GET IT
Times cited: 20
First-in-Human Trial of Epichaperome-Targeted PET in Patients with Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Times cited: 19
Radiopharmacologic screening of antibodies to the unshed ectodomain of MUC16 in ovarian cancer identifies a lead candidate for clinical translation. Nuclear medicine and biology. 2020 Academic Article GET IT
⁸⁹Zr-PET imaging of DNA double-strand breaks for the early monitoring of response following α- and β-particle radioimmunotherapy in a mouse model of pancreatic ductal adenocarcinoma. Theranostics. 2020 Academic Article GET IT
Times cited: 17
Inhibiting cancer metabolism by aromatic carbohydrate amphiphiles that act as antagonists of the glucose transporter GLUT1. Chemical Science. 2020 Article GET IT
3D-Printable Platform for High-Throughput Small-Animal Imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020 Letter GET IT
Times cited: 4
CD38-targeted Immuno-PET of Multiple Myeloma: From Xenograft Models to First-in-Human Imaging. Radiology. 2020 Academic Article GET IT
Times cited: 88
pH-Responsive Polymers for Improving the Signal-to-Noise Ratio of Hypoxia PET Imaging with [¹⁸ F]Fluoromisonidazole. Macromolecular rapid communications. 2020 Academic Article GET IT
Times cited: 6
Safety and Feasibility of PARP1/2 Imaging with ¹⁸F-PARPi in Patients with Head and Neck Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Times cited: 46
A Systematic Evaluation of Antibody Modification and ⁸⁹Zr-Radiolabeling for Optimized Immuno-PET. Bioconjugate chemistry. 2020 Academic Article GET IT
Times cited: 36
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers. Cancer discovery. 2020 Academic Article GET IT
Times cited: 185
Inhibiting cancer metabolism by aromatic carbohydrate amphiphiles that act as antagonists of the glucose transporter GLUT1. Chemical science. 2020 Academic Article GET IT
Times cited: 24
First-in-Humans Trial of Dasatinib-Derivative Tracer for Tumor Kinase-Targeted PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020 Academic Article GET IT
Times cited: 4
Radiotheranostics: a roadmap for future development. The Lancet. Oncology. 2020 Review GET IT
Times cited: 173
Design and preclinical evaluation of nanostars for the passive pretargeting of tumor tissue. Nuclear medicine and biology. 2020 Academic Article GET IT
Times cited: 17
Manipulating the In Vivo Behaviour of ⁶⁸Ga with Tris(Hydroxypyridinone) Chelators: Pretargeting and Blood Clearance. International journal of molecular sciences. 2020 Academic Article GET IT
Times cited: 11
iNOS Regulates the Therapeutic Response of Pancreatic Cancer Cells to Radiotherapy. Cancer research. 2020 Academic Article GET IT
Times cited: 37
Targeted Brain Tumor Radiotherapy Using an Auger Emitter. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Times cited: 77
Changing of the Guard at Molecular Imaging & Biology. Molecular imaging and biology. 2020 Editorial Article GET IT
Correction to: The 2019 World Molecular Imaging Congress (WMIC) and Molecular Imaging and Biology (MIB) Awards. 2020 GET IT
The 2019 World Molecular Imaging Congress (WMIC) and Molecular Imaging and Biology (MIB) Awards. Molecular imaging and biology. 2020 Editorial Article GET IT
The Impact of Positron Range on PET Resolution, Evaluated with Phantoms and PHITS Monte Carlo Simulations for Conventional and Non-conventional Radionuclides. Molecular imaging and biology. 2020 Academic Article GET IT
Times cited: 55
Demarcation of Sepsis-Induced Peripheral and Central Acidosis with pH (Low) Insertion Cycle Peptide. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020 Academic Article GET IT
Times cited: 12
PET/CT Imaging with an ¹⁸F-Labeled Galactodendritic Unit in a Galectin-1-Overexpressing Orthotopic Bladder Cancer Model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020 Academic Article GET IT
Times cited: 4
Delivery of polymeric nanostars for molecular imaging and endoradiotherapy through the enhanced permeability and retention (EPR) effect. Theranostics. 2020 Academic Article GET IT
Times cited: 74
ImmunoPET Predicts Response to Met-targeted Radioligand Therapy in Models of Pancreatic Cancer Resistant to Met Kinase Inhibitors. Theranostics. 2020 Academic Article GET IT
Times cited: 22
The Influence of Glycans-Specific Bioconjugation on the FcγRI Binding and In vivo Performance of ⁸⁹Zr-DFO-Pertuzumab. Theranostics. 2020 Academic Article GET IT
Times cited: 41
HER2-Targeted PET Imaging and Therapy of Hyaluronan-Masked HER2-Overexpressing Breast Cancer. Molecular pharmaceutics. 2019 Academic Article GET IT
Times cited: 21
Multimodality labeling strategies for the investigation of nanocrystalline cellulose biodistribution in a mouse model of breast cancer. Nuclear medicine and biology. 2019 Academic Article GET IT
Times cited: 14
Paradigms for Precision Medicine in Epichaperome Cancer Therapy. Cancer cell. 2019 Academic Article GET IT
Times cited: 46
First-in-Humans Imaging with ⁸⁹Zr-Df-IAB22M2C Anti-CD8 Minibody in Patients with Solid Malignancies: Preliminary Pharmacokinetics, Biodistribution, and Lesion Targeting. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2019 Academic Article GET IT
Times cited: 176
Retooling a Blood-Based Biomarker: Phase I Assessment of the High-Affinity CA19-9 Antibody HuMab-5B1 for Immuno-PET Imaging of Pancreatic Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 48
Phase I Trial of Well-Differentiated Neuroendocrine Tumors (NETs) with Radiolabeled Somatostatin Antagonist ¹⁷⁷Lu-Satoreotide Tetraxetan. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 73
An ⁸⁹Zr-HDL PET Tracer Monitors Response to a CSF1R Inhibitor. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2019 Academic Article GET IT
Times cited: 27
Biodistribution and Dosimetry of Intraventricularly Administered ¹²⁴I-Omburtamab in Patients with Metastatic Leptomeningeal Tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2019 Academic Article GET IT
Times cited: 32
Improved synthesis of the bifunctional chelator p-SCN-Bn-HOPO. Organic & biomolecular chemistry. 2019 Academic Article GET IT
Times cited: 11
PARaDIM: A PHITS-Based Monte Carlo Tool for Internal Dosimetry with Tetrahedral Mesh Computational Phantoms. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2019 Academic Article GET IT
Times cited: 30
Acid specific dark quencher QC1 pHLIP for multi-spectral optoacoustic diagnoses of breast cancer. Scientific reports. 2019 Academic Article GET IT
Times cited: 18
Multimodal Positron Emission Tomography Imaging to Quantify Uptake of ⁸⁹Zr-Labeled Liposomes in the Atherosclerotic Vessel Wall. Bioconjugate chemistry. 2019 Academic Article GET IT
Times cited: 27
Temporal Modulation of HER2 Membrane Availability Increases Pertuzumab Uptake and Pretargeted Molecular Imaging of Gastric Tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2019 Academic Article GET IT
Times cited: 27
A rapid bead-based radioligand binding assay for the determination of target-binding fraction and quality control of radiopharmaceuticals. Nuclear medicine and biology. 2019 Academic Article GET IT
Times cited: 39
Toward the Optimization of Click-Mediated Pretargeted Radioimmunotherapy. Molecular pharmaceutics. 2019 Academic Article GET IT
Times cited: 20
A Conversation Between Michael Phelps and Jason Lewis. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2019 Article GET IT
Assessment of Simplified Methods for Quantification of ¹⁸F-FDHT Uptake in Patients with Metastatic Castration-Resistant Prostate Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2019 Academic Article GET IT
Times cited: 11
Trastuzumab gold-conjugates: synthetic approach and in vitro evaluation of anticancer activities in breast cancer cell lines. Chemical communications (Cambridge, England). 2019 Academic Article GET IT
Times cited: 25
Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy. Nature communications. 2018 Academic Article GET IT
Times cited: 89
EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer. Cancer discovery. 2018 Academic Article GET IT
Times cited: 124
Biodistribution and radiation dose estimates for ⁶⁸Ga-DOTA-JR11 in patients with metastatic neuroendocrine tumors. European journal of nuclear medicine and molecular imaging. 2018 Academic Article GET IT
Times cited: 43
Leveraging Bioorthogonal Click Chemistry to Improve ²²⁵Ac-Radioimmunotherapy of Pancreatic Ductal Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis. JACC. Cardiovascular imaging. 2018 Academic Article GET IT
Times cited: 72
Tumor-Specific Zr-89 Immuno-PET Imaging in a Human Bladder Cancer Model. Molecular imaging and biology. 2018 Academic Article GET IT
Times cited: 23
Harnessing Androgen Receptor Pathway Activation for Targeted Alpha Particle Radioimmunotherapy of Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 20
A PET Imaging Strategy for Interrogating Target Engagement and Oncogene Status in Pancreatic Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Times cited: 12
Leveraging PET to image folate receptor α therapy of an antibody-drug conjugate. EJNMMI research. 2018 Academic Article GET IT
Times cited: 13
Clinical Potential of Human Epidermal Growth Factor Receptor 2 and Human Epidermal Growth Factor Receptor 3 Imaging in Breast Cancer. PET clinics. 2018 Review GET IT
Times cited: 21
Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial. The Lancet. Oncology. 2018 Academic Article GET IT
Times cited: 198
Imaging EGFR and HER3 through ⁸⁹Zr-labeled MEHD7945A (Duligotuzumab). Scientific reports. 2018 Academic Article GET IT
Times cited: 16
Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer. Nature communications. 2018 Academic Article GET IT
Times cited: 39
Imaging of human epidermal growth factor receptors for patient selection and response monitoring - From PET imaging and beyond. Cancer letters. 2018 Information Resource GET IT
Times cited: 19
Reproducibility and Repeatability of Semiquantitative ¹⁸F-Fluorodihydrotestosterone Uptake Metrics in Castration-Resistant Prostate Cancer Metastases: A Prospective Multicenter Study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Academic Article GET IT
Times cited: 22
Preclinical optimization of antibody-based radiopharmaceuticals for cancer imaging and radionuclide therapy-Model, vector, and radionuclide selection. Journal of labelled compounds & radiopharmaceuticals. 2018 Review GET IT
Times cited: 29
PARP-1-Targeted Radiotherapy in Mouse Models of Glioblastoma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Academic Article GET IT
Times cited: 55
Click-Mediated Pretargeted Radioimmunotherapy of Colorectal Carcinoma. Molecular pharmaceutics. 2018 Academic Article GET IT
Times cited: 39
The inverse electron-demand Diels-Alder reaction as a new methodology for the synthesis of ²²⁵Ac-labelled radioimmunoconjugates. Chemical communications (Cambridge, England). 2018 Academic Article GET IT
Times cited: 34
Bioorthogonal Masking of Circulating Antibody-TCO Groups Using Tetrazine-Functionalized Dextran Polymers. Bioconjugate chemistry. 2018 Academic Article GET IT
Times cited: 40
Positron Emission Tomography/Computed Tomography-Based Assessments of Androgen Receptor Expression and Glycolytic Activity as a Prognostic Biomarker for Metastatic Castration-Resistant Prostate Cancer. JAMA oncology. 2018 Academic Article GET IT
Times cited: 90
In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of ¹⁸F-(2S,4R)-4-Fluoroglutamine. Radiology. 2018 Academic Article GET IT
Times cited: 85
Fc-Mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models. Cancer research. 2018 Academic Article GET IT
Times cited: 79
Pretargeting of internalizing trastuzumab and cetuximab with a ¹⁸F-tetrazine tracer in xenograft models. EJNMMI research. 2017 Academic Article GET IT
Times cited: 66
89Zr-Trastuzumab PET/CT for Detection of Human Epidermal Growth Factor Receptor 2-Positive Metastases in Patients With Human Epidermal Growth Factor Receptor 2-Negative Primary Breast Cancer. Clinical nuclear medicine. 2017 Academic Article GET IT
Times cited: 99
Current status and future challenges for molecular imaging. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences. 2017 Information Resource GET IT
Times cited: 7
First-in-Human Human Epidermal Growth Factor Receptor 2-Targeted Imaging Using ⁸⁹Zr-Pertuzumab PET/CT: Dosimetry and Clinical Application in Patients with Breast Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Academic Article GET IT
Times cited: 134
A phase II study of radioimmunotherapy with intraventricular ¹³¹ I-3F8 for medulloblastoma. Pediatric blood & cancer. 2017 Academic Article GET IT
Times cited: 52
Exploring Structural Parameters for Pretargeting Radioligand Optimization. Journal of medicinal chemistry. 2017 Academic Article GET IT
Times cited: 50
Multiplexed imaging for diagnosis and therapy. Nature biomedical engineering. 2017 Review GET IT
Times cited: 121
Noninvasive ⁸⁹Zr-Transferrin PET Shows Improved Tumor Targeting Compared with ¹⁸F-FDG PET in MYC-Overexpressing Human Triple-Negative Breast Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Academic Article GET IT
Times cited: 30
Targeted PET imaging strategy to differentiate malignant from inflamed lymph nodes in diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 2017 Academic Article GET IT
Times cited: 26
Long-Half-Life ⁸⁹Zr-Labeled Radiotracers Can Guide Percutaneous Biopsy Within the PET/CT Suite Without Reinjection of Radiotracer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Academic Article GET IT
Times cited: 11
Biodistribution and Dosimetry of ¹⁸F-Meta-Fluorobenzylguanidine: A First-in-Human PET/CT Imaging Study of Patients with Neuroendocrine Malignancies. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Academic Article GET IT
Times cited: 97
Human Epidermal Growth Factor Receptor 2-Targeted PET/Single- Photon Emission Computed Tomography Imaging of Breast Cancer: Noninvasive Measurement of a Biomarker Integral to Tumor Treatment and Prognosis. PET clinics. 2017 Review GET IT
Times cited: 49
Antibodies Against Specific MUC16 Glycosylation Sites Inhibit Ovarian Cancer Growth. ACS chemical biology. 2017 Academic Article GET IT
Times cited: 32
Pharmacokinetics, Biodistribution, and Radiation Dosimetry for ⁸⁹Zr-Trastuzumab in Patients with Esophagogastric Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Academic Article GET IT
Times cited: 102
Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer. Cancer research. 2017 Academic Article GET IT
Times cited: 87
Applications of pHLIP Technology for Cancer Imaging and Therapy. Trends in biotechnology. 2017 Review GET IT
Times cited: 91
Multinuclear NMR and MRI Reveal an Early Metabolic Response to mTOR Inhibition in Sarcoma. Cancer research. 2017 Academic Article GET IT
Times cited: 17
⁸⁹Zr-DFO-AMG102 Immuno-PET to Determine Local Hepatocyte Growth Factor Protein Levels in Tumors for Enhanced Patient Selection. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2017 Academic Article GET IT
Times cited: 32
Preloading with Unlabeled CA19.9 Targeted Human Monoclonal Antibody Leads to Improved PET Imaging with ⁸⁹Zr-5B1. Molecular pharmaceutics. 2017 Academic Article GET IT
Times cited: 34
Noninvasive Measurement of mTORC1 Signaling with ⁸⁹Zr-Transferrin. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Academic Article GET IT
Times cited: 19
Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis. Science translational medicine. 2016 Academic Article GET IT
Times cited: 19
Click Chemistry and Radiochemistry: The First 10 Years. Bioconjugate chemistry. 2016 Review GET IT
Times cited: 199
Prospective Clinical Trial of ¹⁸F-Fluciclovine PET/CT for Determining the Response to Neoadjuvant Therapy in Invasive Ductal and Invasive Lobular Breast Cancers. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 49
Establishment of the In Vivo Efficacy of Pretargeted Radioimmunotherapy Utilizing Inverse Electron Demand Diels-Alder Click Chemistry. Molecular cancer therapeutics. 2016 Academic Article GET IT
Times cited: 88
Imaging biomarker roadmap for cancer studies. Nature reviews. Clinical oncology. 2016 Conference Paper GET IT
Times cited: 812
The epichaperome is an integrated chaperome network that facilitates tumour survival. Nature. 2016 Academic Article GET IT
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A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer. Theranostics. 2016 Academic Article GET IT
Times cited: 53
First-in-Human Imaging with 89Zr-Df-IAB2M Anti-PSMA Minibody in Patients with Metastatic Prostate Cancer: Pharmacokinetics, Biodistribution, Dosimetry, and Lesion Uptake. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 109
PET Imaging of Extracellular pH in Tumors with (64)Cu- and (18)F-Labeled pHLIP Peptides: A Structure-Activity Optimization Study. Bioconjugate chemistry. 2016 Academic Article GET IT
Times cited: 54
Pretargeted PET Imaging Using a Site-Specifically Labeled Immunoconjugate. Bioconjugate chemistry. 2016 Academic Article GET IT
Times cited: 60
Selective Imaging of VEGFR-1 and VEGFR-2 Using 89Zr-Labeled Single-Chain VEGF Mutants. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 23
Fully automated synthesis of [(18) F]fluoro-dihydrotestosterone ([(18) F]FDHT) using the FlexLab module. Journal of labelled compounds & radiopharmaceuticals. 2016 Academic Article GET IT
Times cited: 12
A comparative evaluation of the chelators H4octapa and CHX-A″-DTPA with the therapeutic radiometal (90)Y. Nuclear medicine and biology. 2016 Academic Article GET IT
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Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy. Nature communications. 2016 Academic Article GET IT
Times cited: 100
In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models. JACC. Cardiovascular imaging. 2016 Academic Article GET IT
Times cited: 88
Synthesis and evaluation of an (18)F-labeled pyrimidine-pyridine amine for targeting CXCR4 receptors in gliomas. Nuclear medicine and biology. 2016 Academic Article GET IT
Times cited: 12
Detection of HER2-Positive Metastases in Patients with HER2-Negative Primary Breast Cancer Using 89Zr-Trastuzumab PET/CT. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 150
Molecular Imaging of Ovarian Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Review GET IT
Times cited: 16
Initial Results of a Prospective Clinical Trial of 18F-Fluciclovine PET/CT in Newly Diagnosed Invasive Ductal and Invasive Lobular Breast Cancers. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 32
Preclinical 89Zr Immuno-PET of High-Grade Serous Ovarian Cancer and Lymph Node Metastasis. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 36
Radiosynthesis of the iodine-124 labeled Hsp90 inhibitor PU-H71. Journal of labelled compounds & radiopharmaceuticals. 2016 Academic Article GET IT
Times cited: 18
Applying ⁸⁹Zr-Transferrin To Study the Pharmacology of Inhibitors to BET Bromodomain Containing Proteins. Molecular pharmaceutics. 2016 Academic Article GET IT
Times cited: 12
Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America. 2015 Academic Article GET IT
Times cited: 85
p-SCN-Bn-HOPO: A Superior Bifunctional Chelator for (89)Zr ImmunoPET. Bioconjugate chemistry. 2015 Academic Article GET IT
Times cited: 110
(18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry. Bioconjugate chemistry. 2015 Academic Article GET IT
Times cited: 135
Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2015 Academic Article GET IT
Times cited: 88
Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation. Cancer research. 2015 Academic Article GET IT
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Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics. Molecular pharmaceutics. 2015 Academic Article GET IT
Times cited: 90
Precision Medicine…Visualized-a Message from the President of the WMIC. Molecular imaging and biology. 2015 Editorial Article GET IT
A Phase I/II Study for Analytic Validation of 89Zr-J591 ImmunoPET as a Molecular Imaging Agent for Metastatic Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Academic Article GET IT
Times cited: 167
PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2015 Academic Article GET IT
Times cited: 146
Fully-automated synthesis of 16β-(18)F-fluoro-5α-dihydrotestosterone (FDHT) on the ELIXYS radiosynthesizer. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2015 Academic Article GET IT
Times cited: 9
Low incidence of radionecrosis in children treated with conventional radiation therapy and intrathecal radioimmunotherapy. Journal of neuro-oncology. 2015 Academic Article GET IT
Times cited: 25
PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer. Science translational medicine. 2015 Academic Article GET IT
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Evaluation of hypoxia with copper-labeled diacetyl-bis(N-methylthiosemicarbazone). Seminars in nuclear medicine. 2015 Review GET IT
Times cited: 34
The bioconjugation and radiosynthesis of 89Zr-DFO-labeled antibodies. Journal of visualized experiments : JoVE. 2015 Academic Article GET IT
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Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo. Science translational medicine. 2015 Academic Article GET IT
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Harnessing the bioorthogonal inverse electron demand Diels-Alder cycloaddition for pretargeted PET imaging. Journal of visualized experiments : JoVE. 2015 Academic Article GET IT
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Challenges of Pancreatic Cancer. Cancer journal (Sudbury, Mass.). 2015 Review GET IT
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Chemoenzymatic strategy for the synthesis of site-specifically labeled immunoconjugates for multimodal PET and optical imaging. Bioconjugate chemistry. 2014 Academic Article GET IT
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Annotating STEAP1 regulation in prostate cancer with 89Zr immuno-PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2014 Academic Article GET IT
Times cited: 24
Synthesis and evaluation of (18)F-labeled ATP competitive inhibitors of topoisomerase II as probes for imaging topoisomerase II expression. European journal of medicinal chemistry. 2014 Academic Article GET IT
Times cited: 11
What a difference a carbon makes: H₄octapa vs H₄C3octapa, ligands for In-111 and Lu-177 radiochemistry. Inorganic chemistry. 2014 Academic Article GET IT
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⁸⁹Zr-huJ591 immuno-PET imaging in patients with advanced metastatic prostate cancer. European journal of nuclear medicine and molecular imaging. 2014 Academic Article GET IT
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CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. Genes & development. 2014 Academic Article GET IT
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A modular labeling strategy for in vivo PET and near-infrared fluorescence imaging of nanoparticle tumor targeting. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2014 Academic Article GET IT
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Targeting breast tumors with pH (low) insertion peptides. Molecular pharmaceutics. 2014 Academic Article GET IT
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In vivo imaging of GLP-1R with a targeted bimodal PET/fluorescence imaging agent. Bioconjugate chemistry. 2014 Academic Article GET IT
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Development of a minimal saponin vaccine adjuvant based on QS-21. Nature chemistry. 2014 Academic Article GET IT
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Alternative chelator for ⁸⁹Zr radiopharmaceuticals: radiolabeling and evaluation of 3,4,3-(LI-1,2-HOPO). Journal of medicinal chemistry. 2014 Academic Article GET IT
Times cited: 145
Noninvasive Imaging of PSMA in prostate tumors with (89)Zr-Labeled huJ591 engineered antibody fragments: the faster alternatives. Molecular pharmaceutics. 2014 Academic Article GET IT
Times cited: 69
Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 40
Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis. ChemistryOpen. 2014 Academic Article GET IT
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Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer. Science signaling. 2014 Academic Article GET IT
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Pairwise comparison of 89Zr- and 124I-labeled cG250 based on positron emission tomography imaging and nonlinear immunokinetic modeling: in vivo carbonic anhydrase IX receptor binding and internalization in mouse xenografts of clear-cell renal cell carcinoma. European journal of nuclear medicine and molecular imaging. 2014 Academic Article GET IT
Times cited: 68
Imaging the norepinephrine transporter in neuroblastoma: a comparison of [18F]-MFBG and 123I-MIBG. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
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H6phospa-trastuzumab: bifunctional methylenephosphonate-based chelator with 89Zr, 111In and 177Lu. Dalton transactions (Cambridge, England : 2003). 2014 Academic Article GET IT
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Influence of free fatty acids on glucose uptake in prostate cancer cells. Nuclear medicine and biology. 2013 Academic Article GET IT
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Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals. Inorganic chemistry. 2013 Academic Article GET IT
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(18)F-labeled-bioorthogonal liposomes for in vivo targeting. Bioconjugate chemistry. 2013 Academic Article GET IT
Times cited: 75
Synthesis and evaluation of 18F-labeled benzylguanidine analogs for targeting the human norepinephrine transporter. European journal of nuclear medicine and molecular imaging. 2013 Academic Article GET IT
Times cited: 50
A prospective pilot study of (89)Zr-J591/prostate specific membrane antigen positron emission tomography in men with localized prostate cancer undergoing radical prostatectomy. The Journal of urology. 2013 Academic Article GET IT
Times cited: 68
Applying PET to broaden the diagnostic utility of the clinically validated CA19.9 serum biomarker for oncology. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Academic Article GET IT
Times cited: 59
Feasibility and predictability of perioperative PET and estrogen receptor ligand in patients with invasive breast cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Academic Article GET IT
Times cited: 64
H(4)octapa-trastuzumab: versatile acyclic chelate system for 111In and 177Lu imaging and therapy. Journal of the American Chemical Society. 2013 Academic Article GET IT
Times cited: 75
Sandmeyer reaction repurposed for the site-selective, non-oxidizing radioiodination of fully-deprotected peptides: studies on the endogenous opioid peptide α-neoendorphin. Bioorganic & medicinal chemistry letters. 2013 Academic Article GET IT
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Fatty acid synthase is a key target in multiple essential tumor functions of prostate cancer: uptake of radiolabeled acetate as a predictor of the targeted therapy outcome. PloS one. 2013 Academic Article GET IT
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Enzyme-mediated methodology for the site-specific radiolabeling of antibodies based on catalyst-free click chemistry. Bioconjugate chemistry. 2013 Academic Article GET IT
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A pretargeted PET imaging strategy based on bioorthogonal Diels-Alder click chemistry. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Academic Article GET IT
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The growing impact of bioorthogonal click chemistry on the development of radiopharmaceuticals. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Review GET IT
Times cited: 113
Monitoring afatinib treatment in HER2-positive gastric cancer with 18F-FDG and 89Zr-trastuzumab PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Academic Article GET IT
Times cited: 93
Antilipolytic drug boosts glucose metabolism in prostate cancer. Nuclear medicine and biology. 2013 Academic Article GET IT
Times cited: 5
Imaging tumor burden in the brain with 89Zr-transferrin. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2012 Academic Article GET IT
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(89)Zr-labeled paramagnetic octreotide-liposomes for PET-MR imaging of cancer. Pharmaceutical research. 2012 Academic Article GET IT
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H(2)azapa: a versatile acyclic multifunctional chelator for (67)Ga, (64)Cu, (111)In, and (177)Lu. Inorganic chemistry. 2012 Academic Article GET IT
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Annotating MYC status with 89Zr-transferrin imaging. Nature medicine. 2012 Academic Article GET IT
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PET imaging with ⁸⁹Zr: from radiochemistry to the clinic. Nuclear medicine and biology. 2012 Review GET IT
Times cited: 343
Efficient (18)F-labeling of large 37-amino-acid pHLIP peptide analogues and their biological evaluation. Bioconjugate chemistry. 2012 Academic Article GET IT
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An improved strategy for the synthesis of [¹⁸F]-labeled arabinofuranosyl nucleosides. Nuclear medicine and biology. 2012 Academic Article GET IT
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Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen. Cancer discovery. 2012 Academic Article GET IT
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Dosimetry of 18F-labeled tyrosine kinase inhibitor SKI-249380, a dasatinib-tracer for PET imaging. Molecular imaging and biology. 2012 Academic Article GET IT
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89Zr-labeled dextran nanoparticles allow in vivo macrophage imaging. Bioconjugate chemistry. 2011 Academic Article GET IT
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Ex vivo sentinel lymph node mapping in laparoscopic resection of colon cancer. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 2011 Academic Article GET IT
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Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90. Nature chemical biology. 2011 Academic Article GET IT
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Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand Diels-Alder click chemistry. Bioconjugate chemistry. 2011 Academic Article GET IT
Times cited: 140
Targeting the internal epitope of prostate-specific membrane antigen with 89Zr-7E11 immuno-PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2011 Academic Article GET IT
Times cited: 52
The next generation of positron emission tomography radiopharmaceuticals in oncology. Seminars in nuclear medicine. 2011 Review GET IT
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Intraoperative imaging of positron emission tomographic radiotracers using Cerenkov luminescence emissions. Molecular imaging. 2011 Academic Article GET IT
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A practical guide to the construction of radiometallated bioconjugates for positron emission tomography. Dalton transactions (Cambridge, England : 2003). 2011 Academic Article GET IT
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Magnitude of enhanced permeability and retention effect in tumors with different phenotypes: 89Zr-albumin as a model system. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2011 Academic Article GET IT
Times cited: 146
Role of metalation in the topoisomerase IIα inhibition and antiproliferation activity of a series of α-heterocyclic-N4-substituted thiosemicarbazones and their Cu(II) complexes. Journal of medicinal chemistry. 2011 Academic Article GET IT
Times cited: 178
The synthesis and evaluation of N1-(4-(2-[18F]-fluoroethyl)phenyl)-N8-hydroxyoctanediamide ([18F]-FESAHA), a PET radiotracer designed for the delineation of histone deacetylase expression in cancer. Nuclear medicine and biology. 2011 Academic Article GET IT
Times cited: 15
Imaging and treating tumor vasculature with targeted radiolabeled carbon nanotubes. International journal of nanomedicine. 2010 Academic Article GET IT
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89Zr-DFO-J591 for immunoPET of prostate-specific membrane antigen expression in vivo. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2010 Academic Article GET IT
Times cited: 363
Cerenkov luminescence imaging of medical isotopes. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2010 Academic Article GET IT
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Improved synthesis of 2'-deoxy-2'-[18F]-fluoro-1-beta-D-arabinofuranosyl-5-iodouracil ([18F]-FIAU). Nuclear medicine and biology. 2010 Academic Article GET IT
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Clickable bifunctional radiometal chelates for peptide labeling. Chemical communications (Cambridge, England). 2010 Academic Article GET IT
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Unconventional nuclides for radiopharmaceuticals. Molecular imaging. 2010 Review GET IT
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Measuring the pharmacodynamic effects of a novel Hsp90 inhibitor on HER2/neu expression in mice using Zr-DFO-trastuzumab. PloS one. 2010 Academic Article GET IT
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Nitroimidazole conjugates of bis(thiosemicarbazonato)64Cu(II) - Potential combination agents for the PET imaging of hypoxia. Journal of inorganic biochemistry. 2009 Academic Article GET IT
Times cited: 48
Functionalised copper-64 complexes as precursors of potential PET imaging agents for neurodegenerative disorders. New Journal of Chemistry. 2009 Article GET IT
Standardized methods for the production of high specific-activity zirconium-89. Nuclear medicine and biology. 2009 Academic Article GET IT
Times cited: 359
A novel technology for the imaging of acidic prostate tumors by positron emission tomography. Cancer research. 2009 Academic Article GET IT
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Radiopharmaceuticals in preclinical and clinical development for monitoring of therapy with PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2009 Review GET IT
Times cited: 90
(64)Cu-labeled CB-TE2A and diamsar-conjugated RGD peptide analogs for targeting angiogenesis: comparison of their biological activity. Nuclear medicine and biology. 2009 Academic Article GET IT
Times cited: 90
Assessing tumor hypoxia by positron emission tomography with Cu-ATSM. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... 2009 Review GET IT
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Bromination from the macroscopic level to the tracer radiochemical level: (76)Br radiolabeling of aromatic compounds via electrophilic substitution. Bioconjugate chemistry. 2009 Academic Article GET IT
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Melanoma imaging using (111)In-, (86)Y- and (68)Ga-labeled CHX-A''-Re(Arg11)CCMSH. Nuclear medicine and biology. 2009 Academic Article GET IT
Times cited: 53
In vivo biodistribution, PET imaging, and tumor accumulation of 86Y- and 111In-antimindin/RG-1, engineered antibody fragments in LNCaP tumor-bearing nude mice. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2009 Academic Article GET IT
Times cited: 68
Copper-64 Radiopharmaceuticals for Oncologic Imaging. PET clinics. 2009 Academic Article GET IT
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Synthesis and characterization of the copper(II) complexes of new N2S2-donor macrocyclic ligands: synthesis and in vivo evaluation of the (64)Cu complexes. Dalton transactions (Cambridge, England : 2003). 2008 Academic Article GET IT
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Tumor hypoxia detected by positron emission tomography with 60Cu-ATSM as a predictor of response and survival in patients undergoing Neoadjuvant chemoradiotherapy for rectal carcinoma: a pilot study. Diseases of the colon and rectum. 2008 Academic Article GET IT
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Autoradiographic and small-animal PET comparisons between (18)F-FMISO, (18)F-FDG, (18)F-FLT and the hypoxic selective (64)Cu-ATSM in a rodent model of cancer. Nuclear medicine and biology. 2008 Academic Article GET IT
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Evaluation of a bromine-76-labeled progestin 16alpha,17alpha-dioxolane for breast tumor imaging and radiotherapy: in vivo biodistribution and metabolic stability studies. Nuclear medicine and biology. 2008 Academic Article GET IT
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An imaging comparison of 64Cu-ATSM and 60Cu-ATSM in cancer of the uterine cervix. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2008 Academic Article GET IT
Times cited: 172
In vitro and in vivo evaluation of bifunctional bisthiosemicarbazone 64Cu-complexes for the positron emission tomography imaging of hypoxia. Journal of medicinal chemistry. 2008 Academic Article GET IT
Times cited: 74
Examining the relationship between Cu-ATSM hypoxia selectivity and fatty acid synthase expression in human prostate cancer cell lines. Nuclear medicine and biology. 2008 Academic Article GET IT
Times cited: 51
1-11C-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2008 Academic Article GET IT
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Assessing tumor hypoxia in cervical cancer by PET with 60Cu-labeled diacetyl-bis(N4-methylthiosemicarbazone). Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2008 Academic Article GET IT
Times cited: 178
Workshop on the production, application and clinical translation of ''non-standard'' PET nuclides: a meeting report. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... 2007 Conference Paper GET IT
Times cited: 21
Synthesis, in vitro and in vivo characterization of (64)Cu(I) complexes derived from hydrophilic tris(hydroxymethyl)phosphane and 1,3,5-triaza-7-phosphaadamantane ligands. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2007 Academic Article GET IT
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Cu-ATSM: a radiopharmaceutical for the PET imaging of hypoxia. Dalton transactions (Cambridge, England : 2003). 2007 Academic Article GET IT
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Gallium-68-labeled DOTA-rhenium-cyclized alpha-melanocyte-stimulating hormone analog for imaging of malignant melanoma. Nuclear medicine and biology. 2007 Academic Article GET IT
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Diagnostic and prognostic value of ambulatory ECG (Holter) monitoring in patients with coronary heart disease: a review. Journal of thrombosis and thrombolysis. 2007 Review GET IT
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Molecular imaging of gastrin-releasing peptide receptor-positive tumors in mice using 64Cu- and 86Y-DOTA-(Pro1,Tyr4)-bombesin(1-14). Bioconjugate chemistry. 2007 Academic Article GET IT
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An anatomical study of tibial metaphyseal/diaphyseal mismatch during revision total knee arthroplasty. The Journal of arthroplasty. 2007 Academic Article GET IT
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In vivo imaging in a murine model of glioblastoma. Neurosurgery. 2007 Academic Article GET IT
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Production of non-standard PET radionuclides and the application of radiopharmaceuticals labeled with these nuclides. Ernst Schering Research Foundation workshop. 2007 Review GET IT
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Radiometal-labeled somatostatin analogs for applications in cancer imaging and therapy. Methods in molecular biology (Clifton, N.J.). 2007 Review GET IT
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Synthesis and biologic evaluation of 64Cu-labeled rhenium-cyclized alpha-MSH peptide analog using a cross-bridged cyclam chelator. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2007 Academic Article GET IT
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64Cu-azabicyclo[3.2.2]nonane thiosemicarbazone complexes: radiopharmaceuticals for PET of topoisomerase II expression in tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2006 Academic Article GET IT
Times cited: 28
NuMA influences higher order chromatin organization in human mammary epithelium. Molecular biology of the cell. 2006 Academic Article GET IT
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Imaging oxygenation of human tumours. European radiology. 2006 Review GET IT
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Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy. International journal of radiation biology. 2006 Review GET IT
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Validation of a novel CHX-A'' derivative suitable for peptide conjugation: small animal PET/CT imaging using yttrium-86-CHX-A''-octreotide. Journal of medicinal chemistry. 2006 Academic Article GET IT
Times cited: 43
Assessment of myocardial metabolism in diabetic rats using small-animal PET: a feasibility study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2006 Academic Article GET IT
Times cited: 29
In vivo skeletal imaging of 18F-fluoride with positron emission tomography reveals damage- and time-dependent responses to fatigue loading in the rat ulna. Bone. 2006 Academic Article GET IT
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Assessment of myocardial blood flow using 15O-water and 1-11C-acetate in rats with small-animal PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2006 Academic Article GET IT
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Minimally invasive method of determining blood input function from PET images in rodents. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2006 Academic Article GET IT
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Three-dimensional maximum a posteriori (MAP) imaging with radiopharmaceuticals labeled with three Cu radionuclides. Nuclear medicine and biology. 2006 Academic Article GET IT
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Preparation of high specific activity (86)Y using a small biomedical cyclotron. Nuclear medicine and biology. 2005 Academic Article GET IT
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Measurement of input functions in rodents: challenges and solutions. Nuclear medicine and biology. 2005 Academic Article GET IT
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Identification of a novel prostate tumor target, mindin/RG-1, for antibody-based radiotherapy of prostate cancer. Cancer research. 2005 Academic Article GET IT
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Cell line-dependent differences in uptake and retention of the hypoxia-selective nuclear imaging agent Cu-ATSM. Nuclear medicine and biology. 2005 Academic Article GET IT
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A tat fusion protein-based tumor vaccine for breast cancer. Annals of surgical oncology. 2005 Academic Article GET IT
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Imaging of melanoma using 64Cu- and 86Y-DOTA-ReCCMSH(Arg11), a cyclized peptide analogue of alpha-MSH. Journal of medicinal chemistry. 2005 Academic Article GET IT
Times cited: 118
Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models. International journal of radiation oncology, biology, physics. 2005 Academic Article GET IT
Times cited: 153
Dosimetry of 60/61/62/64Cu-ATSM: a hypoxia imaging agent for PET. European journal of nuclear medicine and molecular imaging. 2005 Academic Article GET IT
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Investigation into 64Cu-labeled Bis(selenosemicarbazone) and Bis(thiosemicarbazone) complexes as hypoxia imaging agents. Nuclear medicine and biology. 2005 Academic Article GET IT
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Basic characterization of 64Cu-ATSM as a radiotherapy agent. Nuclear medicine and biology. 2005 Academic Article GET IT
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Positron-emitting isotopes produced on biomedical cyclotrons. Current medicinal chemistry. 2005 Review GET IT
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Preparation of 66Ga- and 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals. Nuclear medicine and biology. 2003 Academic Article GET IT
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Enhancing targeted radiotherapy by copper(II)diacetyl- bis(N4-methylthiosemicarbazone) using 2-deoxy-D-glucose. Cancer research. 2003 Academic Article GET IT
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Imaging the effects of anti-angiogenic treatments. The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR). 2003 Review GET IT
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[Tc(CO)(3)](+) chemistry: a promising new concept for SPECT? Against. European journal of nuclear medicine and molecular imaging. 2003 Academic Article GET IT
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Intra-tumoral distribution of (64)Cu-ATSM: a comparison study with FDG. Nuclear medicine and biology. 2003 Academic Article GET IT
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Polyclonal antibodies to xenogeneic endothelial cells induce apoptosis and block support of tumor growth in mice. Vaccine. 2003 Academic Article GET IT
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In vivo assessment of tumor hypoxia in lung cancer with 60Cu-ATSM. European journal of nuclear medicine and molecular imaging. 2003 Academic Article GET IT
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Assessing tumor hypoxia in cervical cancer by positron emission tomography with 60Cu-ATSM: relationship to therapeutic response-a preliminary report. International journal of radiation oncology, biology, physics. 2003 Academic Article GET IT
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Delineation of hypoxia in canine myocardium using PET and copper(II)-diacetyl-bis(N(4)-methylthiosemicarbazone). Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2002 Academic Article GET IT
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Small animal imaging. current technology and perspectives for oncological imaging. European journal of cancer. 2002 Review GET IT
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DOTA-D-Tyrl-octreotate: A somatostatin analogue for labeling with metal and halogen radionuclides for cancer imaging and therapy. Bioconjugate Chemistry. 2002 Article GET IT
Copper-64-pyruvaldehyde-bis(N(4)-methylthiosemicarbazone) for the prevention of tumor growth at wound sites following laparoscopic surgery: monitoring therapy response with microPET and magnetic resonance imaging. Cancer research. 2002 Academic Article GET IT
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Molecular imaging: the application of small animal positron emission tomography. Journal of cellular biochemistry. Supplement. 2002 Review GET IT
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Toxicity and dosimetry of (177)Lu-DOTA-Y3-octreotate in a rat model. International journal of cancer. 2001 Academic Article GET IT
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Copper bis(thiosemicarbazone) complexes as hypoxia imaging agents: structure-activity relationships. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2001 Academic Article GET IT
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PET imaging of hypoxia. The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR). 2001 Review GET IT
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Tumor uptake of copper-diacetyl-bis(N(4)-methylthiosemicarbazone): effect of changes in tissue oxygenation. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2001 Academic Article GET IT
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A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy. International journal of radiation oncology, biology, physics. 2001 Academic Article GET IT
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64Cu-TETA-octreotide as a PET imaging agent for patients with neuroendocrine tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2001 Academic Article GET IT
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Copper-64-diacetyl-bis(N4-methylthiosemicarbazone): An agent for radiotherapy. Proceedings of the National Academy of Sciences of the United States of America. 2001 Academic Article GET IT
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Comparative dosimetry of copper-64 and yttrium-90-labeled somatostatin analogs in a tumor-bearing rat model. Cancer biotherapy & radiopharmaceuticals. 2000 Academic Article GET IT
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Copper bis(diphosphine) complexes: radiopharmaceuticals for the detection of multi-drug resistance in tumours by PET. European journal of nuclear medicine. 2000 Academic Article GET IT
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Radiotherapy and dosimetry of 64Cu-TETA-Tyr3-octreotate in a somatostatin receptor-positive, tumor-bearing rat model. Clinical cancer research : an official journal of the American Association for Cancer Research. 1999 Academic Article GET IT
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High purity production and potential applications of copper-60 and copper-61. Nuclear medicine and biology. 1999 Academic Article GET IT
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Comparison of four 64Cu-labeled somatostatin analogues in vitro and in a tumor-bearing rat model: evaluation of new derivatives for positron emission tomography imaging and targeted radiotherapy. Journal of medicinal chemistry. 1999 Academic Article GET IT
Times cited: 102
Utilization of metabolic, transport and receptor-mediated processes to deliver agents for cancer diagnosis. Advanced drug delivery reviews. 1999 Academic Article GET IT
Times cited: 32
In vitro and in vivo evaluation of 64Cu-TETA-Tyr3-octreotate. A new somatostatin analog with improved target tissue uptake. Nuclear medicine and biology. 1999 Academic Article GET IT
Times cited: 89
Metal complexes as diagnostic tools. Coordination Chemistry Reviews. 1999 Article
Evaluation of 64Cu-ATSM in vitro and in vivo in a hypoxic tumor model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1999 Academic Article GET IT
Times cited: 300
Effect of ligand and solvent on chloride ion coordination in anti-tumour copper(I) diphosphine complexes: Synthesis of [Cu(dppe)2]Cl and analogous complexes (dppe = 1,2-bis(diphenylphosphino)ethane). Polyhedron. 1998 Article
Redox-active metal complexes for imaging hypoxic tissues: Structure-activity relationships in copper(II) bis(thiosemicarbazone) complexes. Chemical Communications. 1998 Article
Radiotherapy, toxicity and dosimetry of copper-64-TETA-octreotide in tumor-bearing rats. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1998 Academic Article GET IT
Times cited: 135
Design of hypoxia-targeting radiopharmaceuticals: selective uptake of copper-64 complexes in hypoxic cells in vitro. European journal of nuclear medicine. 1998 Academic Article GET IT
Times cited: 105
Diphosphine bifunctional chelators for low-valent metal ions. Crystal structures of the copper(I) complexes [CuClL¹2] and [CuL¹2][PF6] [L¹ = 2,3-bis(diphenylphosphino)maleic anhydride]. Journal of the Chemical Society - Dalton Transactions. 1997 Article
Copper radionuclides and radiopharmaceuticals in nuclear medicine. Nuclear medicine and biology. 1996 Review GET IT
Times cited: 341
Complexes of potentially tri- and tetra-dentate phosphinothiol ligands with Mo, W, Re, Fe, Ru, Os, Rh, Ir and Ni. Journal of the Chemical Society - Dalton Transactions. 1996 Article
Copper(I) bis(diphosphine) complexes as a basis for radiopharmaceuticals for positron emission tomography and targeted radiotherapy. Chemical Communications. 1996 Article
Rhenium complex of a triply deprotonated chelated thiosemicarbazide and its conversion to a nitride complex via a hydrazide intermediate. Crystal structure of [ReCl2(NH)(NHNH2)(PPh3)2]. Journal of the Chemical Society, Dalton Transactions. 1995 Article GET IT
The preparation of rhenium(V) oxo and imido complexes with Et2NCSNHCOPh and Et2NCSBC(NH)Ph. The x-ray crystal structure of [ReOCl(PhCONCSNEt2)2]. Polyhedron. 1993 Article GET IT
Abnormal skeletal response to parathyroid hormone in dogs with chronic uremia. Calcified tissue international. 1982 Academic Article GET IT
Times cited: 22
Dissociation of renal cyclic AMP and phosphate responses to parathyroid hormone in uremia. Calcified tissue international. 1979 Academic Article GET IT
Times cited: 1
The C-O binary combination spectra of some pentacarbonyl metal complexes. Journal of the Chemical Society A: Inorganic, Physical, Theoretical. 1968 Article GET IT
1098. The infrared spectra of some addition compounds of aluminium and gallium trihalides. Journal of the Chemical Society (Resumed). 1965 Article GET IT

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Background

education and training

Ph.D., University of Kent (United Kingdom) 1997
M.Sc., University of Essex (United Kingdom) 1993
B.Sc., University of Essex (United Kingdom) 1992

Contact

full name

Jason S. Lewis

VIVO Weill Cornell Medical College

Jason S. Lewis Professor of Radiochemistry and Radiopharmacy in Radiology

Publications

selected publications

Background

education and training

Contact

full name

primary email