The Journal of biological chemistry

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Correction: The barley lectin, horcolin, binds high-mannose glycans in a multivalent fashion, enabling high-affinity, specific inhibition of cellular HIV infection. 2021
FREE FATTY ACIDS INHIBIT AN ION-COUPLED MEMBRANE TRANSPORTER BY DISSIPATING THE ION GRADIENT. 2024
The sodium-proton exchangers sNHE and NHE1 control plasma membrane hyperpolarization in mouse sperm. 2024
DNA polymerase ζ has robust reverse transcriptase activity relative to other cellular DNA polymerases. 2024
Structural and biochemical analysis of highly similar HLA-B allotypes differentially associated with type 1 diabetes. 2024
Molecular characterization of Rft1, an ER membrane protein associated with congenital disorder of glycosylation RFT1-CDG. 2024
E41K Mutation Activates Bruton's Tyrosine Kinase by Stabilizing an Inositol Hexakisphosphate dependent Invisible Dimer. 2024
Cyclic AMP binding to a universal stress protein in Mycobacterium tuberculosis is essential for viability. 2024
Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere. 2024
Factors governing the transcriptome changes and chronological lifespan of fission yeast during phosphate starvation. 2024
A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors. 2024
PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin. 2024
Multiple mechanisms of self-association of chemokine receptors CXCR4 and CCR5 demonstrated by deep mutagenesis.. 299. 2023
Coordination between the Ndc80 complex and dynein is essential for microtubule plus-end capture by kinetochores during early mitosis.. 299. 2023
Human DNA polymerase η promotes RNA-templated error-free repair of DNA double-strand breaks.. 299. 2023
Regulatory role of endoplasmic reticulum resident chaperone protein ERp29 in anti-murine β-coronavirus host cell response.. 299. 2022
Multi-OMICs analysis reveals metabolic and epigenetic changes associated with macrophage polarization.. 298. 2022
Molecular and Functional Interactions of Alpha-Synuclein with Rab3a. 2022
Phosphatidylinositol Phosphates Modulate Interactions between the StarD4 Sterol Trafficking Protein and Lipid Membranes. 2022
Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1. 2022
Deciphering functional redundancy and energetics of malate oxidation in mycobacteria. 2022
Copper(II) import and reduction are dependent on His-Met clusters in the extracellular amino terminus of human Copper Transporter-1. 2022
Post-translational modifications within tau paired helical filament nucleating motifs perturb microtubule interactions and oligomer formation. 2021
A Retinoic Acid Receptor β2 Agonist Attenuates Transcriptome and Metabolome Changes Underlying Non-Alcohol-Associated Fatty Liver Disease. 2021
A bioorthogonal chemical reporter for fatty acid synthase-dependent protein acylation.. 297. 2021
Quantification of NADH:ubiquinone oxidoreductase (complex I) content in biological samples.. 297. 2021
Metabolic flexibility maintains proliferation and migration of FGFR signaling-deficient lymphatic endothelial cells.. 297. 2021
Elimination of GPI2 suppresses glycosylphosphatidylinositol GlcNAc transferase activity and alters GPI glycan modification in Trypanosoma brucei.. 297. 2021
Roles of the ubiquitin ligase CUL4B and ADP-ribosyltransferase TiPARP in TCDD-induced nuclear export and proteasomal degradation of the transcription factor AHR.. 297. 2021
Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice.. 297. 2021
Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.. 296. 2021
The small molecule DIPQUO promotes osteogenic differentiation via inhibition of glycogen synthase kinase 3-beta signaling.. 296. 2021
Selective targeting of the inactive state of hematopoietic cell kinase (Hck) with a stable curcumin derivative.. 296. 2021
Rediscovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis.. 296. 2021
Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis. 2021
Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling.. 296. 2020
Targeted reduction of cholesterol uptake in cholesterol-addicted lymphoma cells blocks turnover of oxidized lipids to cause ferroptosis.. 296. 2020
HIV-1 Gag protein with or without p6 specifically dimerizes on the viral RNA packaging signal.. 295. 2020
Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells.. 295. 2020
The barley lectin, horcolin, binds high-mannose glycans in a multivalent fashion, enabling high-affinity, specific inhibition of cellular HIV infection.. 295. 2020
Hairpin RNA-induced conformational change of a eukaryotic-specific lysyl-tRNA synthetase extension and role of adjacent anticodon-binding domain.. 295. 2020
Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau.. 295. 2020
Regulation of gene expression during the fasting-feeding cycle of the liver displays mouse strain specificity.. 295. 2020
ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).. 295. 2020
Withdrawal: Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease: Evidence for involvement of the transcription factor Egr-1.. 295. 2020
RNase L promotes the formation of unique ribonucleoprotein granules distinct from stress granules.. 295. 2020
A universal stress protein in Mycobacterium smegmatis sequesters the cAMP-regulated lysine acyltransferase and is essential for biofilm formation.. 295. 2019
Long noncoding RNAs sustain high expression levels of exogenous octamer-binding protein 4 by sponging regulatory microRNAs during cellular reprogramming.. 294. 2019
High-resolution protein-protein interaction mapping using all-versus-all sequencing (AVA-Seq).. 294. 2019
Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival.. 294. 2019
p90 ribosomal S6 kinase (RSK) phosphorylates myosin phosphatase and thereby controls edge dynamics during cell migration.. 294. 2019
Dihydronicotinamide riboside is a potent NAD⁺ concentration enhancer in vitro and in vivo.. 294. 2019
Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity.. 294. 2019
Ethanol promotes differentiation of embryonic stem cells through retinoic acid receptor-γ.. 294. 2019
Stabilization of the V2 loop improves the presentation of V2 loop-associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers.. 294. 2019
HIV-1 anchor inhibitors and membrane fusion inhibitors target distinct but overlapping steps in virus entry.. 294. 2019
Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of glycerol-3-phosphate acyltransferase 1-induced steatosis.. 294. 2018
Prostaglandin E₂ down-regulates sirtuin 1 (SIRT1), leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection.. 294. 2018
Scrambling of natural and fluorescently tagged phosphatidylinositol by reconstituted G protein-coupled receptor and TMEM16 scramblases.. 293. 2018
Apoptotic β-cells induce macrophage reprogramming under diabetic conditions.. 293. 2018
Inhibition of the CD36 receptor reduces visceral fat accumulation and improves insulin resistance in obese mice carrying the BDNF-Val66Met variant.. 293. 2018
Structural mapping of fluorescently-tagged, functional nhTMEM16 scramblase in a lipid bilayer.. 293. 2018
Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells.. 293. 2018
Disruption of protein kinase A localization induces acrosomal exocytosis in capacitated mouse sperm.. 293. 2018
Structural basis of sterol binding and transport by a yeast StARkin domain.. 293. 2018
Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon.. 293. 2018
A long noncoding (lnc)RNA governs expression of the phosphate transporter Pho84 in fission yeast and has cascading effects on the flanking prt lncRNA and pho1 genes.. 293. 2018
Histone variant H3.3-mediated chromatin remodeling is essential for paternal genome activation in mouse preimplantation embryos.. 293. 2018
Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α-converting enzyme.. 293. 2018
Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways.. 293. 2017
Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers.. 293. 2017
Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload-induced angiogenesis.. 292. 2017
An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.. 292. 2017
Increased heme synthesis in yeast induces a metabolic switch from fermentation to respiration even under conditions of glucose repression.. 292. 2017
The long non-coding RNA GAS5 regulates transforming growth factor β (TGF-β)-induced smooth muscle cell differentiation via RNA Smad-binding elements.. 292. 2017
HMG-CoA synthase 1 is a synthetic lethal partner of BRAF^V600E in human cancers.. 292. 2017
Scavenger receptor B1 (SR-B1) profoundly excludes high density lipoprotein (HDL) apolipoprotein AII as it nibbles HDL-cholesteryl ester.. 292. 2017
The role of transmembrane segment 5 (TM5) in Na2 release and the conformational transition of neurotransmitter:sodium symporters toward the inward-open state.. 292. 2017
Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer.. 292. 2016
RFT1 Protein Affects Glycosylphosphatidylinositol (GPI) Anchor Glycosylation.. 292. 2016
Notch Pathway Is Activated via Genetic and Epigenetic Alterations and Is a Therapeutic Target in Clear Cell Renal Cancer.. 292. 2016
Distinct Receptor Tyrosine Kinase Subsets Mediate Anti-HER2 Drug Resistance in Breast Cancer.. 292. 2016
Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase-1-mediated Epigenetic Regulation of Nuclear Factor κB-driven Gene Expression.. 291. 2016
Microvesicle-mediated Wnt/β-Catenin Signaling Promotes Interspecies Mammary Stem/Progenitor Cell Growth.. 291. 2016
Cell Surface CD36 Protein in Monocyte/Macrophage Contributes to Phagocytosis during the Resolution Phase of Ischemic Stroke in Mice.. 291. 2016
Conformational Dynamics on the Extracellular Side of LeuT Controlled by Na+ and K+ Ions and the Protonation State of Glu290.. 291. 2016
Chemically Programmed Bispecific Antibodies in Diabody Format.. 291. 2016
Identification of a Membrane-bound Prepore Species Clarifies the Lytic Mechanism of Actinoporins.. 291. 2016
Structural and Biological Interaction of hsc-70 Protein with Phosphatidylserine in Endosomal Microautophagy.. 291. 2016
Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.. 291. 2016
Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.. 291. 2016
The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action.. 291. 2016
Quantitative Correlation between Infectivity and Gp120 Density on HIV-1 Virions Revealed by Optical Trapping Virometry.. 291. 2016
The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions.. 291. 2016
Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site.. 291. 2016
Altered Plasma Profile of Antioxidant Proteins as an Early Correlate of Pancreatic β Cell Dysfunction.. 291. 2016
Central Role of Pyruvate Kinase in Carbon Co-catabolism of Mycobacterium tuberculosis.. 291. 2016
Cell Autonomous and Nonautonomous Function of CUL4B in Mouse Spermatogenesis.. 291. 2016
SIRT1 Limits Adipocyte Hyperplasia through c-Myc Inhibition.. 291. 2015
Calcineurin Aγ is a Functional Phosphatase That Modulates Synaptic Vesicle Endocytosis.. 291. 2015
Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems.. 291. 2015
Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3.. 290. 2015
Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.. 291. 2015
Oligomerization and Membrane-binding Properties of Covalent Adducts Formed by the Interaction of α-Synuclein with the Toxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde (DOPAL).. 290. 2015
Substrate-induced unlocking of the inner gate determines the catalytic efficiency of a neurotransmitter:sodium symporter.. 290. 2015
Vesicular glutamate transporter 1 orchestrates recruitment of other synaptic vesicle cargo proteins during synaptic vesicle recycling.. 290. 2015
Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation.. 290. 2015
Regulation of Catalytic and Non-catalytic Functions of the Drosophila Ste20 Kinase Slik by Activation Segment Phosphorylation.. 290. 2015
The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD.. 290. 2015
Metallothionein-I/II Promotes Axonal Regeneration in the Central Nervous System.. 290. 2015
Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters.. 290. 2015
Alteration of Electrostatic Surface Potential Enhances Affinity and Tumor Killing Properties of Anti-ganglioside GD2 Monoclonal Antibody hu3F8.. 290. 2015
A universal stress protein (USP) in mycobacteria binds cAMP.. 290. 2015
The Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site.. 290. 2015
Immunosilencing a highly immunogenic protein trimerization domain.. 290. 2015
The Groucho-associated phosphatase PPM1B displaces Pax transactivation domain interacting protein (PTIP) to switch the transcription factor Pax2 from a transcriptional activator to a repressor.. 290. 2015
The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding.. 290. 2015
Oxysterol-binding protein-related protein 8 (ORP8) increases sensitivity of hepatocellular carcinoma cells to Fas-mediated apoptosis.. 290. 2015
An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency.. 290. 2014
The PDZ motif of the α1C subunit is not required for surface trafficking and adrenergic modulation of CaV1.2 channel in the heart.. 290. 2014
Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass.. 290. 2014
Pivotal role of extended linker 2 in the activation of Gα by G protein-coupled receptor.. 290. 2014
p38α MAPK is required for tooth morphogenesis and enamel secretion.. 290. 2014
WASp family verprolin-homologous protein-2 (WAVE2) and Wiskott-Aldrich syndrome protein (WASp) engage in distinct downstream signaling interactions at the T cell antigen receptor site.. 289. 2014
Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist.. 289. 2014
cAMP-responsive element-binding protein (CREB) and cAMP co-regulate activator protein 1 (AP1)-dependent regeneration-associated gene expression and neurite growth.. 289. 2014
A signal transducer and activator of transcription 3·Nuclear Factor κB (Stat3·NFκB) complex is necessary for the expression of fascin in metastatic breast cancer cells in response to interleukin (IL)-6 and tumor necrosis factor (TNF)-α.. 289. 2014
RecO protein initiates DNA recombination and strand annealing through two alternative DNA binding mechanisms.. 289. 2014
Fbxo45 inhibits calcium-sensitive proteolysis of N-cadherin and promotes neuronal differentiation.. 289. 2014
The second sodium site in the dopamine transporter controls cation permeation and is regulated by chloride.. 289. 2014
Regulation of protein phosphatase 1I by Cdc25C-associated kinase 1 (C-TAK1) and PFTAIRE protein kinase.. 289. 2014
Direct evidence of an elongation factor-Tu/Ts·GTP·Aminoacyl-tRNA quaternary complex.. 289. 2014
The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity.. 289. 2014
SCUBE3 (signal peptide-CUB-EGF domain-containing protein 3) modulates fibroblast growth factor signaling during fast muscle development.. 289. 2014
Ca2+ influx via the Na+/Ca2+ exchanger is enhanced in malignant hyperthermia skeletal muscle.. 289. 2014
Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells.. 289. 2014
Mutations in the X-linked intellectual disability gene, zDHHC9, alter autopalmitoylation activity by distinct mechanisms.. 289. 2014
Mitochondrial tRNA 5'-editing in Dictyostelium discoideum and Polysphondylium pallidum.. 289. 2014
C-terminal Src kinase (Csk)-mediated phosphorylation of eukaryotic elongation factor 2 (eEF2) promotes proteolytic cleavage and nuclear translocation of eEF2.. 289. 2014
A KcsA/MloK1 chimeric ion channel has lipid-dependent ligand-binding energetics.. 289. 2014
p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression.. 289. 2014
Allosteric modulation of a cannabinoid G protein-coupled receptor: binding site elucidation and relationship to G protein signaling.. 289. 2013
Structure of Clostridium difficile PilJ exhibits unprecedented divergence from known type IV pilins.. 289. 2013
N-terminal acetylation stabilizes N-terminal helicity in lipid- and micelle-bound α-synuclein and increases its affinity for physiological membranes.. 289. 2013
Novel mechanism of positive versus negative regulation by thyroid hormone receptor β1 (TRβ1) identified by genome-wide profiling of binding sites in mouse liver.. 289. 2013
The E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates.. 288. 2013
Compartmentalization of distinct cAMP signaling pathways in mammalian sperm.. 288. 2013
CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor.. 288. 2013
Inositol 1,4,5-trisphosphate (IP3) receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility.. 288. 2013
Atypical protein kinase Cλ is critical for growth factor receptor-induced dorsal ruffle turnover and cell migration.. 288. 2013
Sphingosine kinases are not required for inflammatory responses in macrophages.. 288. 2013
Thioesterase superfamily member 2/Acyl-CoA thioesterase 13 (Them2/Acot13) regulates adaptive thermogenesis in mice.. 288. 2013
A mental retardation-linked nonsense mutation in cereblon is rescued by proteasome inhibition.. 288. 2013
Duplication and functional specialization of the telomere-capping protein Cdc13 in Candida species.. 288. 2013
Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis.. 288. 2013
Cytochrome p450 cyp26a1 alters spinal motor neuron subtype identity in differentiating embryonic stem cells.. 288. 2013
A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase.. 288. 2013
Disruption of multivesicular body vesicles does not affect major histocompatibility complex (MHC) class II-peptide complex formation and antigen presentation by dendritic cells.. 288. 2013
Mice lacking C1q are protected from high fat diet-induced hepatic insulin resistance and impaired glucose homeostasis.. 288. 2013
Influence of allosteric regulators on individual steps in the reaction catalyzed by Mycobacterium tuberculosis 2-hydroxy-3-oxoadipate synthase.. 288. 2013
Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action.. 288. 2013
The phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesis.. 288. 2013
An epigenetic antimalarial resistance mechanism involving parasite genes linked to nutrient uptake.. 288. 2013
Glycoprotein biosynthesis in a eukaryote lacking the membrane protein Rft1.. 288. 2013
The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates.. 288. 2013
Crystal structure of peroxide stress regulator from Streptococcus pyogenes provides functional insights into the mechanism of oxidative stress sensing.. 288. 2013
Semiquinone and cluster N6 signals in His-tagged proton-translocating NADH:ubiquinone oxidoreductase (complex I) from Escherichia coli.. 288. 2013
Elongation factor Ts directly facilitates the formation and disassembly of the Escherichia coli elongation factor Tu·GTP·aminoacyl-tRNA ternary complex.. 288. 2013
The auxiliary subunit KChIP2 is an essential regulator of homeostatic excitability.. 288. 2013
Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis.. 288. 2013
Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease.. 288. 2013
Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.. 288. 2013
Atypical protein kinase Cι is required for Wnt3a-dependent neurite outgrowth and binds to phosphorylated dishevelled 2.. 288. 2013
Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.. 288. 2013
Post-synaptic density-95 (PSD-95) binding capacity of G-protein-coupled receptor 30 (GPR30), an estrogen receptor that can be identified in hippocampal dendritic spines.. 288. 2013
Zebrafish scube1 (signal peptide-CUB (complement protein C1r/C1s, Uegf, and Bmp1)-EGF (epidermal growth factor) domain-containing protein 1) is involved in primitive hematopoiesis.. 288. 2012
The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization.. 288. 2012
Type 10 soluble adenylyl cyclase is overexpressed in prostate carcinoma and controls proliferation of prostate cancer cells.. 288. 2012
Sphingosine 1-phosphate receptor signaling regulates proper embryonic vascular patterning.. 288. 2012
Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis.. 288. 2012
Molecular mechanism of fascin function in filopodial formation.. 288. 2012
Activation of liver X receptor induces macrophage interleukin-5 expression.. 287. 2012
A refined analysis of superoxide production by mitochondrial sn-glycerol 3-phosphate dehydrogenase.. 287. 2012
Site-specific phosphorylation of the p65 protein subunit mediates selective gene expression by differential NF-κB and RNA polymerase II promoter recruitment.. 288. 2012
Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.. 287. 2012
Steric hindrance mutagenesis in the conserved extracellular vestibule impedes allosteric binding of antidepressants to the serotonin transporter.. 287. 2012
The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critical for repair of DNA alkylation damage and stable association at DNA damage sites.. 287. 2012
T-cell acute leukemia 1 (TAL1) regulation of erythropoietin receptor and association with excessive erythrocytosis.. 287. 2012
Properties of a novel PBP2A protein homolog from Staphylococcus aureus strain LGA251 and its contribution to the β-lactam-resistant phenotype.. 287. 2012
Substrate-bound crystal structures reveal features unique to Mycobacterium tuberculosis N-acetyl-glucosamine 1-phosphate uridyltransferase and a catalytic mechanism for acetyl transfer.. 287. 2012
Enhancement of NEIL1 protein-initiated oxidized DNA base excision repair by heterogeneous nuclear ribonucleoprotein U (hnRNP-U) via direct interaction.. 287. 2012
The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor.. 287. 2012
Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein.. 287. 2012
Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions.. 287. 2012
The protein Zfand5 binds and stabilizes mRNAs with AU-rich elements in their 3'-untranslated regions.. 287. 2012
Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers.. 287. 2012
Inhibition of mycobacterial infection by the tumor suppressor PTEN.. 287. 2012
Endoproteolytic cleavage of TUG protein regulates GLUT4 glucose transporter translocation.. 287. 2012
Peroxisome Proliferator-activated receptor γ activation by ligands and dephosphorylation induces proprotein convertase subtilisin kexin type 9 and low density lipoprotein receptor expression.. 287. 2012
Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine.. 287. 2012
Increased resting intracellular calcium modulates NF-κB-dependent inducible nitric-oxide synthase gene expression in dystrophic mdx skeletal myotubes.. 287. 2012
Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo.. 287. 2012
Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress.. 287. 2012
p53 basic C terminus regulates p53 functions through DNA binding modulation of subset of target genes.. 287. 2012
Hsp70 promotes epithelial sodium channel functional expression by increasing its association with coat complex II and its exit from endoplasmic reticulum.. 287. 2012
Familial Alzheimer disease presenilin-1 mutations alter the active site conformation of γ-secretase.. 287. 2012
Engulfment protein GULP is regulator of transforming growth factor-β response in ovarian cells.. 287. 2012
Reconstitution of glucosylceramide flip-flop across endoplasmic reticulum: implications for mechanism of glycosphingolipid biosynthesis.. 287. 2012
Microtubules regulate hypoxia-inducible factor-1α protein trafficking and activity: implications for taxane therapy.. 287. 2012
Autophagy promotes intracellular degradation of type I collagen induced by transforming growth factor (TGF)-β1.. 287. 2012
Down-regulation of CMTM8 induces epithelial-to-mesenchymal transition-like changes via c-MET/extracellular signal-regulated kinase (ERK) signaling.. 287. 2012
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.. 287. 2012
Identification of small molecule inhibitors of neurite loss induced by Aβ peptide using high content screening.. 287. 2012
Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts.. 287. 2012
Reciprocal inhibition between the transforming growth factor-β-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) mitogen-activated protein kinase kinase kinases and its suppression by TAK1-binding protein 2 (TAB2), an adapter protein for TAK1.. 287. 2011
E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress.. 287. 2011
Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3'-phosphatase in maintenance of mitochondrial genome.. 287. 2011
Gastric inhibitory peptide controls adipose insulin sensitivity via activation of cAMP-response element-binding protein and p110β isoform of phosphatidylinositol 3-kinase.. 286. 2011
Regulation of anterior chamber drainage by bicarbonate-sensitive soluble adenylyl cyclase in the ciliary body.. 286. 2011
Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes.. 286. 2011
Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.. 286. 2011
Signal transducers and activators of transcription 3 (STAT3) directly regulates cytokine-induced fascin expression and is required for breast cancer cell migration.. 286. 2011
Interaction of the M4 segment with other transmembrane segments is required for surface expression of mammalian α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.. 286. 2011
Aging neural progenitor cells have decreased mitochondrial content and lower oxidative metabolism.. 286. 2011
Genomic analysis reveals a novel nuclear factor-κB (NF-κB)-binding site in Alu-repetitive elements.. 286. 2011
InvA protein is a Nudix hydrolase required for infection by pathogenic Leptospira in cell lines and animals.. 286. 2011
Group V phospholipase A2 in bone marrow-derived myeloid cells and bronchial epithelial cells promotes bacterial clearance after Escherichia coli pneumonia.. 286. 2011
Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK).. 286. 2011
CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.. 286. 2011
Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization.. 286. 2011
Novel variant of thyroglobulin promoter triggers thyroid autoimmunity through an epigenetic interferon alpha-modulated mechanism.. 286. 2011
A novel role of endothelin-1 in linking Toll-like receptor 7-mediated inflammation to fibrosis in congenital heart block.. 286. 2011
Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation.. 286. 2011
A phosphodiesterase 2A isoform localized to mitochondria regulates respiration.. 286. 2011
A peroxisome proliferator-activated receptor gamma (PPARgamma)/PPARgamma coactivator 1beta autoregulatory loop in adipocyte mitochondrial function.. 286. 2011
SUMOylation-regulated protein phosphorylation, evidence from quantitative phosphoproteomics analyses.. 286. 2011
Identification of novel interaction sites that determine specificity between fibroblast growth factor homologous factors and voltage-gated sodium channels.. 286. 2011
Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q.. 286. 2011
Structural and functional studies indicating altered redox properties of hemoglobin E: implications for production of bioactive nitric oxide.. 286. 2011
ERp29 regulates DeltaF508 and wild-type cystic fibrosis transmembrane conductance regulator (CFTR) trafficking to the plasma membrane in cystic fibrosis (CF) and non-CF epithelial cells.. 286. 2011
A chimeric HIV-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (GM-CSF) domain induces enhanced antibody and T cell responses.. 286. 2011
A257T linker region mutant of T7 helicase-primase protein is defective in DNA loading and rescued by T7 DNA polymerase.. 286. 2011
Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex.. 286. 2011
Role of the STIM1 C-terminal domain in STIM1 clustering.. 286. 2011
Lack of cAMP-response element-binding protein 1 in the hypothalamus causes obesity.. 286. 2011
Complex contribution of cyclophilin D to Ca2+-induced permeability transition in brain mitochondria, with relation to the bioenergetic state.. 286. 2010
Preferential repair of oxidized base damage in the transcribed genes of mammalian cells.. 286. 2010
The N-terminal peptide of mammalian GTP cyclohydrolase I is an autoinhibitory control element and contributes to binding the allosteric regulatory protein GFRP.. 286. 2010
FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress.. 286. 2010
Decreased diacylglycerol metabolism enhances ERK activation and augments CD8+ T cell functional responses.. 286. 2010
The C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3'-maturation.. 286. 2010
Feedback regulation of endothelial cell surface plasmin generation by PKC-dependent phosphorylation of annexin A2.. 286. 2010
Epigenomic reorganization of the clustered Hox genes in embryonic stem cells induced by retinoic acid.. 286. 2010
The biosynthesis characteristics of TTP and TNF can be regulated through a posttranscriptional molecular loop.. 286. 2010
Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation.. 286. 2010
Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117.. 285. 2010
Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.. 286. 2010
TGF-{beta}1 protects against mesangial cell apoptosis via induction of autophagy.. 285. 2010
Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity.. 285. 2010
Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution.. 285. 2010
The membrane subunit NuoL(ND5) is involved in the indirect proton pumping mechanism of Escherichia coli complex I.. 285. 2010
Selective fusion of azurophilic granules with Leishmania-containing phagosomes in human neutrophils.. 285. 2010
Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool.. 285. 2010
Oxidized cholesteryl esters and phospholipids in zebrafish larvae fed a high cholesterol diet: macrophage binding and activation.. 285. 2010
Decreased expression of ARV1 results in cholesterol retention in the endoplasmic reticulum and abnormal bile acid metabolism.. 285. 2010
Convergence of Ser/Thr and two-component signaling to coordinate expression of the dormancy regulon in Mycobacterium tuberculosis.. 285. 2010
Specific Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: potential etiological linkage to neurodegenerative diseases.. 285. 2010
The lipid-binding domain of wild type and mutant alpha-synuclein: compactness and interconversion between the broken and extended helix forms.. 285. 2010
Stimulation of platelet-derived growth factor receptor beta (PDGFRbeta) activates ADAM17 and promotes metalloproteinase-dependent cross-talk between the PDGFRbeta and epidermal growth factor receptor (EGFR) signaling pathways.. 285. 2010
Stat3 directly controls the expression of Tbx5, Nkx2.5, and GATA4 and is essential for cardiomyocyte differentiation of P19CL6 cells.. 285. 2010
System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency.. 285. 2010
Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation.. 285. 2010
Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1).. 285. 2010
Conserved 3'-untranslated region sequences direct subcellular localization of chaperone protein mRNAs in neurons.. 285. 2010
Engineering of single Ig superfamily domain of intercellular adhesion molecule 1 (ICAM-1) for native fold and function.. 285. 2010
Regulation of hepatic six transmembrane epithelial antigen of prostate 4 (STEAP4) expression by STAT3 and CCAAT/enhancer-binding protein alpha.. 285. 2010
Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner.. 285. 2010
Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts.. 285. 2010
G alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR).. 285. 2010
Pro-hormone secretogranin II regulates dense core secretory granule biogenesis in catecholaminergic cells.. 285. 2010
c-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion.. 285. 2010
GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes.. 285. 2010
Inhibition of ERK1/2 and activation of liver X receptor synergistically induce macrophage ABCA1 expression and cholesterol efflux.. 285. 2009
Identification of SMARCAL1 as a component of the DNA damage response.. 284. 2009
Nuclear localization of the p75 neurotrophin receptor intracellular domain.. 285. 2009
AAA+ chaperone ClpX regulates dynamics of prokaryotic cytoskeletal protein FtsZ.. 285. 2009
Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications.. 285. 2009
Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosis.. 285. 2009
A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors.. 285. 2009
The full-length unprocessed hedgehog protein is an active signaling molecule.. 285. 2009
Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis.. 285. 2009
SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.. 285. 2009
Lack of oxygen deactivates mitochondrial complex I: implications for ischemic injury?. 284. 2009
Employing a recombinant HLA-DR3 expression system to dissect major histocompatibility complex II-thyroglobulin peptide dynamism: a genetic, biochemical, and reverse immunological perspective.. 284. 2009
A distributed set of interactions controls mu2 functionality in the role of AP-2 as a sorting adaptor in synaptic vesicle endocytosis.. 284. 2009
Cholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate.. 284. 2009
Sterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death.. 284. 2009
Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease.. 284. 2009
Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency.. 284. 2009
Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner.. 284. 2009
Detailed mechanistic insights into HIV-1 sensitivity to three generations of fusion inhibitors.. 284. 2009
FACT and the proteasome promote promoter chromatin disassembly and transcriptional initiation.. 284. 2009
Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9.. 284. 2009
Transforming growth factor-beta (TGF-beta1) activates TAK1 via TAB1-mediated autophosphorylation, independent of TGF-beta receptor kinase activity in mesangial cells.. 284. 2009
Cell surface biliverdin reductase mediates biliverdin-induced anti-inflammatory effects via phosphatidylinositol 3-kinase and Akt.. 284. 2009
Direct selection of monoclonal phosphospecific antibodies without prior phosphoamino acid mapping.. 284. 2009
Kinase-dependent regulation of inositol 1,4,5-trisphosphate-dependent Ca2+ release during oocyte maturation.. 284. 2009
Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells.. 284. 2009
Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosis.. 284. 2009
Yeast surface two-hybrid for quantitative in vivo detection of protein-protein interactions via the secretory pathway.. 284. 2009
p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling.. 284. 2009
The minichromosome maintenance proteins 2-7 (MCM2-7) are necessary for RNA polymerase II (Pol II)-mediated transcription.. 284. 2009
The protein farnesyltransferase regulates HDAC6 activity in a microtubule-dependent manner.. 284. 2009
DNA-binding Domain within the Brh2 N Terminus Is the Primary Interaction Site for Association with DNA.. 284. 2009
Solution structure of the NaV1.2 C-terminal EF-hand domain.. 284. 2009
Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cells.. 284. 2009
let-7 Overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts.. 284. 2009
Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation.. 284. 2008
Sprouty 2 regulates DNA damage-induced apoptosis in Ras-transformed human fibroblasts.. 284. 2008
Residue 17 of sauvagine cross-links to the first transmembrane domain of corticotropin-releasing factor receptor 1 (CRFR1).. 283. 2008
Distinct specificities of Mycobacterium tuberculosis and mammalian proteasomes for N-acetyl tripeptide substrates.. 283. 2008
SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.. 283. 2008
Binding of the unorthodox transcription activator, Crl, to the components of the transcription machinery.. 283. 2008
Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum.. 283. 2008
Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathways.. 283. 2008
Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells.. 283. 2008
Lysyl-tRNA synthetase is a target for mutant SOD1 toxicity in mitochondria.. 283. 2008
RIBEYE recruits Munc119, a mammalian ortholog of the Caenorhabditis elegans protein unc119, to synaptic ribbons of photoreceptor synapses.. 283. 2008
Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1.. 283. 2008
The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells.. 283. 2008
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.. 283. 2008
The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels.. 283. 2008
BCL6-mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a p53-dependent pathway in a cell context-dependent manner.. 283. 2008
Identification of the mitochondrial ND3 subunit as a structural component involved in the active/deactive enzyme transition of respiratory complex I.. 283. 2008
Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis.. 283. 2008
Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli.. 283. 2008
BAT3 interacts with transforming growth factor-beta (TGF-beta) receptors and enhances TGF-beta1-induced type I collagen expression in mesangial cells.. 283. 2008
Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1.. 283. 2008
Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11.. 283. 2008
An intracellular interaction network regulates conformational transitions in the dopamine transporter.. 283. 2008
Sex-dependent effect of BAG1 in ameliorating motor deficits of Huntington disease transgenic mice.. 283. 2008
Structural signatures and membrane helix 4 in GLUT1: inferences from human blood-brain glucose transport mutants.. 283. 2008
cAMP inhibits cell migration by interfering with Rac-induced lamellipodium formation.. 283. 2008
Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein.. 283. 2008
Protein phosphatase 2A is a negative regulator of transforming growth factor-beta1-induced TAK1 activation in mesangial cells.. 283. 2008
Essential role of sequestosome 1/p62 in regulating accumulation of Lys63-ubiquitinated proteins.. 283. 2008
Osteopontin regulates actin cytoskeleton and contributes to cell proliferation in primary erythroblasts.. 283. 2008
Nuclear non-coding RNAs are transcribed from the centromeres of Plasmodium falciparum and are associated with centromeric chromatin.. 283. 2007
Shear- and compression-induced chondrocyte transcription requires MAPK activation in cartilage explants.. 283. 2007
Characterization of tRNA-dependent peptide bond formation by MurM in the synthesis of Streptococcus pneumoniae peptidoglycan.. 283. 2007
Identification of novel direct Stat3 target genes for control of growth and differentiation.. 283. 2007
Evidence that sprouty 2 is necessary for sarcoma formation by H-Ras oncogene-transformed human fibroblasts.. 283. 2007
Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen. The potential for replication-associated repair of oxidized bases in mammalian genomes.. 283. 2007
Genetic deletion of low density lipoprotein receptor impairs sterol-induced mouse macrophage ABCA1 expression. A new SREBP1-dependent mechanism.. 283. 2007
Differential role of NADP+ and NADPH in the activity and structure of GDP-D-mannose 4,6-dehydratase from two chlorella viruses.. 283. 2007
S-nitrosation of mitochondrial complex I depends on its structural conformation.. 282. 2007
Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia.. 282. 2007
Shear-induced disulfide bond formation regulates adhesion activity of von Willebrand factor.. 282. 2007
The cyclophilin-like domain of Ran-binding protein-2 modulates selectively the activity of the ubiquitin-proteasome system and protein biogenesis.. 282. 2007
Mechanical stretch inhibits oxidized low density lipoprotein-induced apoptosis in vascular smooth muscle cells by up-regulating integrin alphavbeta3 and stablization of PINCH-1.. 282. 2007
Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements.. 282. 2007
Specificity of Gbetagamma signaling to Kir3 channels depends on the helical domain of pertussis toxin-sensitive Galpha subunits.. 282. 2007
Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2.. 282. 2007
Site-specific effects of peptide lipidation on beta-amyloid aggregation and cytotoxicity.. 282. 2007
Regulation of human cytidine triphosphate synthetase 1 by glycogen synthase kinase 3.. 282. 2007
The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1.. 282. 2007
N-terminal truncation of antiapoptotic MCL1, but not G2/M-induced phosphorylation, is associated with stabilization and abundant expression in tumor cells.. 282. 2007
Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations.. 282. 2007
A molecular link between E2F-1 and the MAPK cascade.. 282. 2007
An assembled complex IV maintains the stability and activity of complex I in mammalian mitochondria.. 282. 2007
A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells.. 282. 2007
Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5.. 282. 2007
Mycobacterial UvrD1 is a Ku-dependent DNA helicase that plays a role in multiple DNA repair events, including double-strand break repair.. 282. 2007
Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism.. 282. 2007
RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.. 282. 2007
A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome.. 282. 2007
SHP-2 regulates cell growth by controlling the mTOR/S6 kinase 1 pathway.. 282. 2007
Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.. 282. 2007
A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36.. 282. 2006
Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation.. 282. 2006
The role of activating protein 1 in the transcriptional regulation of the human FCGR2B promoter mediated by the -343 G -> C polymorphism associated with systemic lupus erythematosus.. 282. 2006
Proteolytic processing of delta-like 1 by ADAM proteases.. 282. 2006
The histone chaperone anti-silencing function 1 stimulates the acetylation of newly synthesized histone H3 in S-phase.. 282. 2006
FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activity.. 282. 2006
Ethanolamine phosphate linked to the first mannose residue of glycosylphosphatidylinositol (GPI) lipids is a major feature of the GPI structure that is recognized by human GPI transamidase.. 281. 2006
A membrane-targeted BID BCL-2 homology 3 peptide is sufficient for high potency activation of BAX in vitro.. 281. 2006
Mutational analysis of Encephalitozoon cuniculi mRNA cap (guanine-N7) methyltransferase, structure of the enzyme bound to sinefungin, and evidence that cap methyltransferase is the target of sinefungin's antifungal activity.. 281. 2006
G proteins G12 and G13 control the dynamic turnover of growth factor-induced dorsal ruffles.. 281. 2006
Neprilysin inhibits angiogenesis via proteolysis of fibroblast growth factor-2.. 281. 2006
Regulation of CD4 expression via recycling by HRES-1/RAB4 controls susceptibility to HIV infection.. 281. 2006
Suberoylanilide hydroxamic acid induces Akt-mediated phosphorylation of p300, which promotes acetylation and transcriptional activation of RelA/p65.. 281. 2006
Tracking and elucidating alphavirus-host protein interactions.. 281. 2006
Yaf2 inhibits caspase 8-mediated apoptosis and regulates cell survival during zebrafish embryogenesis.. 281. 2006
State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.. 281. 2006
Shear and compression differentially regulate clusters of functionally related temporal transcription patterns in cartilage tissue.. 281. 2006
Multiple endoplasmic reticulum-to-nucleus signaling pathways coordinate phospholipid metabolism with gene expression by distinct mechanisms.. 281. 2006
TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc.. 281. 2006
The Redox-Bohr group associated with iron-sulfur cluster N2 of complex I.. 281. 2006
Heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2.. 281. 2006
Fibrillar beta-amyloid-stimulated intracellular signaling cascades require Vav for induction of respiratory burst and phagocytosis in monocytes and microglia.. 281. 2006
Interferon regulatory factor 8 regulates RANTES gene transcription in cooperation with interferon regulatory factor-1, NF-kappaB, and PU.1.. 281. 2006
Poxvirus mRNA cap methyltransferase. Bypass of the requirement for the stimulatory subunit by mutations in the catalytic subunit and evidence for intersubunit allostery.. 281. 2006
The glucocorticoid receptor represses cyclin D1 by targeting the Tcf-beta-catenin complex.. 281. 2006
Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1.. 281. 2006
Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation.. 281. 2006
An interaction between insulin-like growth factor-binding protein 2 (IGFBP2) and integrin alpha5 is essential for IGFBP2-induced cell mobility.. 281. 2006
Role of tyrosine kinase Csk in G protein-coupled receptor- and receptor tyrosine kinase-induced fibroblast cell migration.. 281. 2006
Crystal structure and nonhomologous end-joining function of the ligase component of Mycobacterium DNA ligase D.. 281. 2006
Complex role of the vitamin D receptor and its ligand in adipogenesis in 3T3-L1 cells.. 281. 2006
A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation.. 281. 2006
Strict pairing of var promoters and introns is required for var gene silencing in the malaria parasite Plasmodium falciparum.. 281. 2006
Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling.. 281. 2006
NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox.. 281. 2006
Genome-wide transcriptional dependence on TAF1 functional domains.. 281. 2006
Targeting prostaglandin E2 receptors as an alternative strategy to block cyclooxygenase-2-dependent extracellular matrix-induced matrix metalloproteinase-9 expression by macrophages.. 281. 2005
Oncogenic RAS induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints.. 281. 2005
GLUT4 distribution between the plasma membrane and the intracellular compartments is maintained by an insulin-modulated bipartite dynamic mechanism.. 281. 2005
The conserved Leu-724 residue is required for both serine phosphorylation and co-activator recruitment for Stat1-mediated transcription activation in response to interferon-gamma.. 280. 2005
Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system.. 280. 2005
Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival.. 280. 2005
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling.. 280. 2005
Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to vitamin A deficiency.. 280. 2005
A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation.. 280. 2005
Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis.. 280. 2005
The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination.. 280. 2005
Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins.. 280. 2005
Rabphilin localizes with the cell actin cytoskeleton and stimulates association of granules with F-actin cross-linked by {alpha}-actinin.. 280. 2005
A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen.. 280. 2005
The opportunistic pathogen Toxoplasma gondii deploys a diverse legion of invasion and survival proteins.. 280. 2005
The platelet-derived growth factor receptor-beta phosphorylates and activates G protein-coupled receptor kinase-2. A mechanism for feedback inhibition.. 280. 2005
Superoxide radical formation by pure complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica.. 280. 2005
mu-Calpain regulates receptor activator of NF-kappaB ligand (RANKL)-supported osteoclastogenesis via NF-kappaB activation in RAW 264.7 cells.. 280. 2005
Ca2+ influx through L-type Ca2+ channels controls the trailing tail contraction in growth factor-induced fibroblast cell migration.. 280. 2005
Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase.. 280. 2005
A physical and functional constituent of telomerase anchor site.. 280. 2005
PDGF-BB regulates p27 expression through ERK-dependent RNA turn-over in vascular smooth muscle cells.. 280. 2005
Interferon regulatory factor 1 is an essential and direct transcriptional activator for interferon {gamma}-induced RANTES/CCl5 expression in macrophages.. 280. 2005
Caspase-dependent and -independent activation of acid sphingomyelinase signaling.. 280. 2005
Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis.. 280. 2005
Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice.. 280. 2005
Concerted auto-regulation in yeast endosomal t-SNAREs.. 280. 2005
Molecular determinants for the complex binding specificity of the PDZ domain in PICK1.. 280. 2005
Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal.. 280. 2005
Endoplasmic reticulum localization of Gaa1 and PIG-T, subunits of the glycosylphosphatidylinositol transamidase complex.. 280. 2005
Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components.. 280. 2005
Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily.. 280. 2005
Neurotrophin receptor interacting factor (NRIF) is an essential mediator of apoptotic signaling by the p75 neurotrophin receptor.. 280. 2005
Characterization of a conserved C-terminal motif (RSPRR) in ribosomal protein S6 kinase 1 required for its mammalian target of rapamycin-dependent regulation.. 280. 2005
Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells.. 280. 2005
Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity.. 280. 2005
Genome-wide analysis reveals inositol, not choline, as the major effector of Ino2p-Ino4p and unfolded protein response target gene expression in yeast.. 280. 2004
Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.. 280. 2004
Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation.. 280. 2004
Lipid infusion decreases the expression of nuclear encoded mitochondrial genes and increases the expression of extracellular matrix genes in human skeletal muscle.. 280. 2004
The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists.. 280. 2004
Prosurvival and prodeath effects of hypoxia-inducible factor-1alpha stabilization in a murine hippocampal cell line.. 280. 2004
Endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle. Role in cell survival.. 280. 2004
HDQ (1-hydroxy-2-dodecyl-4(1H)quinolone), a high affinity inhibitor for mitochondrial alternative NADH dehydrogenase: evidence for a ping-pong mechanism.. 280. 2004
Differential protein mobility of the gamma-aminobutyric acid, type A, receptor alpha and beta subunit channel-lining segments.. 280. 2004
Structure of the dimeric PufX-containing core complex of Rhodobacter blasticus by in situ atomic force microscopy.. 280. 2004
cis-acting, element-specific transcriptional activity of differentially phosphorylated nuclear factor-kappa B.. 280. 2004
Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice.. 280. 2004
Conformational changes in BID, a pro-apoptotic BCL-2 family member, upon membrane binding. A site-directed spin labeling study.. 280. 2004
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease.. 280. 2004
Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein.. 279. 2004
The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth.. 279. 2004
Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway.. 279. 2004
The histone chaperone Asf1p mediates global chromatin disassembly in vivo.. 279. 2004
The NS5A protein of hepatitis C virus is a zinc metalloprotein.. 279. 2004
The RGS14 GoLoco domain discriminates among Galphai isoforms.. 279. 2004
Calmodulin mediates Ca2+ sensitivity of sodium channels.. 279. 2004
Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2.. 279. 2004
Analysis of a novel prophage-encoded group A Streptococcus extracellular phospholipase A(2).. 279. 2004
An annexin 2 phosphorylation switch mediates p11-dependent translocation of annexin 2 to the cell surface.. 279. 2004
Evaluation of the contribution of different ADAMs to tumor necrosis factor alpha (TNFalpha) shedding and of the function of the TNFalpha ectodomain in ensuring selective stimulated shedding by the TNFalpha convertase (TACE/ADAM17).. 279. 2004
The mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory protein.. 279. 2004
Microglia-derived pronerve growth factor promotes photoreceptor cell death via p75 neurotrophin receptor.. 279. 2004
The transcription factor CCAAT/enhancer-binding protein alpha is required for the intracellular retention of GLUT4.. 279. 2004
Phosphorylation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na(+)/H(+) exchanger regulatory factor.. 279. 2004
Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components.. 279. 2004
Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages.. 279. 2004
Argininosuccinate synthetase is reversibly inactivated by S-nitrosylation in vitro and in vivo.. 279. 2004
DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase.. 279. 2004
Inhibition of TATA binding protein dimerization by RNA polymerase III transcription initiation factor Brf1.. 279. 2004
Regulated production of a peroxisome proliferator-activated receptor-gamma ligand during an early phase of adipocyte differentiation in 3T3-L1 adipocytes.. 279. 2004
Paracrine and autocrine functions of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in brain-derived endothelial cells.. 279. 2004
Transforming growth factor-beta1 stimulates vascular endothelial growth factor 164 via mitogen-activated protein kinase kinase 3-p38alpha and p38delta mitogen-activated protein kinase-dependent pathway in murine mesangial cells.. 279. 2004
Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes.. 279. 2004
The kinase activity of kinase suppressor of Ras1 (KSR1) is independent of bound MEK.. 279. 2004
Collagenolysis-dependent angiogenesis mediated by matrix metalloproteinase-13 (collagenase-3).. 279. 2004
Mechanistic insights from a refined three-dimensional model of integrin alphaIIbbeta3.. 279. 2004
Extracellular matrix-induced cyclooxygenase-2 regulates macrophage proteinase expression.. 279. 2004
Engineering dimer-stabilizing mutations in the TATA-binding protein.. 279. 2004
Distinct roles for Src tyrosine kinase in beta2-adrenergic receptor signaling to MAPK and in receptor internalization.. 279. 2004
Biochemical and genetic analysis of the four DNA ligases of mycobacteria.. 279. 2004
Activation and repression of interleukin-12 p40 transcription by erythroid Kruppel-like factor in macrophages.. 279. 2004
Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP.. 279. 2004
Docking of endothelial nitric oxide synthase (eNOS) to the mitochondrial outer membrane: a pentabasic amino acid sequence in the autoinhibitory domain of eNOS targets a proteinase K-cleavable peptide on the cytoplasmic face of mitochondria.. 279. 2004
Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding.. 279. 2004
Subcellular localization and targeting of N-acetylglucosaminyl phosphatidylinositol de-N-acetylase, the second enzyme in the glycosylphosphatidylinositol biosynthetic pathway.. 279. 2004
A critical intramolecular interaction for protein kinase Cepsilon translocation.. 279. 2004
Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes.. 279. 2004
Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1.. 279. 2004
Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function.. 279. 2004
ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation.. 279. 2004
hGTSE-1 expression stimulates cytoplasmic localization of p53.. 279. 2004
Direct binding of neutral endopeptidase 24.11 to ezrin/radixin/moesin (ERM) proteins competes with the interaction of CD44 with ERM proteins.. 279. 2004
Motifs IV and V in the DEAH box splicing factor Prp22 are important for RNA unwinding, and helicase-defective Prp22 mutants are suppressed by Prp8.. 279. 2003
Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.. 279. 2003
Tumor necrosis factor alpha inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin-like growth factor-I induction of new E2F-1 synthesis.. 279. 2003
Adenovirus E4 gene promotes selective endothelial cell survival and angiogenesis via activation of the vascular endothelial-cadherin/Akt signaling pathway.. 279. 2003
A conserved proline in the last transmembrane segment of Gaa1 is required for glycosylphosphatidylinositol (GPI) recognition by GPI transamidase.. 279. 2003
Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR).. 279. 2003
High level oxacillin and vancomycin resistance and altered cell wall composition in Staphylococcus aureus carrying the staphylococcal mecA and the enterococcal vanA gene complex.. 279. 2003
Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach.. 279. 2003
Structural role of PufX in the dimerization of the photosynthetic core complex of Rhodobacter sphaeroides.. 279. 2003
AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression.. 279. 2003
Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis.. 279. 2003
Delta Np63 alpha expression is regulated by the phosphoinositide 3-kinase pathway.. 278. 2003
Microsomal prostaglandin E2 synthase-1 is induced by conditional expression of RET/PTC in thyroid PCCL3 cells through the activation of the MEK-ERK pathway.. 278. 2003
Cytoplasmic and nuclear delivery of a TAT-derived peptide and a beta-peptide after endocytic uptake into HeLa cells.. 278. 2003
Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling.. 278. 2003
Functional studies of threonine 310 mutations in Glut1: T310I is pathogenic, causing Glut1 deficiency.. 278. 2003
HIV envelope gp120-mediated regulation of osteoclastogenesis via receptor activator of nuclear factor kappa B ligand (RANKL) secretion and its modulation by certain HIV protease inhibitors through interferon-gamma/RANKL cross-talk.. 278. 2003
CITED2-mediated regulation of MMP-1 and MMP-13 in human chondrocytes under flow shear.. 278. 2003
Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.. 278. 2003
Silencing of CDX2 expression in colon cancer via a dominant repression pathway.. 278. 2003
The cytoplasmic domain of the low density lipoprotein (LDL) receptor-related protein, but not that of the LDL receptor, triggers phagocytosis.. 278. 2003
Genetic and biochemical analysis of the functional domains of yeast tRNA ligase.. 278. 2003
T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse.. 278. 2003
Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).. 278. 2003
Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration.. 278. 2003
Nitric oxide activates diverse signaling pathways to regulate gene expression.. 278. 2003
Cerebellar deficits and hyperactivity in mice lacking Smad4.. 278. 2003
Activation of p53 by oxidative stress involves platelet-derived growth factor-beta receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation.. 278. 2003
Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17).. 278. 2003
Inactivation of the tuberous sclerosis complex-1 and -2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and -independent phosphorylation of tuberin.. 278. 2003
Sphingomyelinase activity causes transbilayer lipid translocation in model and cell membranes.. 278. 2003
Plasmodium falciparum var genes are regulated by two regions with separate promoters, one upstream of the coding region and a second within the intron.. 278. 2003
Ca2+-calmodulin-dependent protein kinase II potentiates store-operated Ca2+ current.. 278. 2003
The Escherichia coli RecQ helicase functions as a monomer.. 278. 2003
Repressors of androgen and progesterone receptor action.. 278. 2003
Identification of genes encoding arabinosyltransferases (SCA) mediating developmental modifications of lipophosphoglycan required for sand fly transmission of leishmania major.. 278. 2003
Molecular interaction and enzymatic activity of macrophage migration inhibitory factor with immunorelevant peptides.. 278. 2003
IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization.. 278. 2003
Troglitazone antagonizes tumor necrosis factor-alpha-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-kappaB.. 278. 2003
Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain shedding.. 278. 2003
The RNA-binding protein HuR regulates the expression of cyclooxygenase-2.. 278. 2003
Catalytic properties of ADAM19.. 278. 2003
The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia.. 278. 2003
Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway.. 278. 2003
Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta.. 278. 2003
Serp-1, a viral anti-inflammatory serpin, regulates cellular serine proteinase and serpin responses to vascular injury.. 278. 2003
Kinetic properties of "soluble" adenylyl cyclase. Synergism between calcium and bicarbonate.. 278. 2003
Functional identification of galactosyltransferases (SCGs) required for species-specific modifications of the lipophosphoglycan adhesin controlling Leishmania major-sand fly interactions.. 278. 2003
Genomic correlates of hyperthermostability, an update.. 278. 2003
The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6).. 278. 2003
Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability.. 278. 2003
Negative regulation of T cell activation by placental protein 14 is mediated by the tyrosine phosphatase receptor CD45.. 278. 2003
Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump.. 278. 2003
Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen.. 278. 2003
Membrane lipid organization is critical for human neutrophil polarization.. 278. 2003
PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1.. 278. 2003
The mmaA2 gene of Mycobacterium tuberculosis encodes the distal cyclopropane synthase of the alpha-mycolic acid.. 278. 2002
Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure.. 278. 2002
Interactions between fission yeast Cdk9, its cyclin partner Pch1, and mRNA capping enzyme Pct1 suggest an elongation checkpoint for mRNA quality control.. 278. 2002
Hepatocyte growth factor induces GATA-4 phosphorylation and cell survival in cardiac muscle cells.. 278. 2002
Leptomycin B, an inhibitor of the nuclear export receptor CRM1, inhibits COX-2 expression.. 278. 2002
Conserved N-terminal motifs of telomerase reverse transcriptase required for ribonucleoprotein assembly in vivo.. 278. 2002
Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding.. 278. 2002
Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein.. 278. 2002
BCL-2 improves oxidative phosphorylation and modulates adenine nucleotide translocation in mitochondria of cells harboring mutant mtDNA.. 278. 2002
Structure-function analysis of invasion plasmid antigen C (IpaC) from Shigella flexneri.. 278. 2002
Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation.. 278. 2002
Phosphorylation of the platelet-derived growth factor receptor-beta and epidermal growth factor receptor by G protein-coupled receptor kinase-2. Mechanisms for selectivity of desensitization.. 277. 2002
Modulation of T cell cytokine production by interferon regulatory factor-4.. 277. 2002
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for activation of p38alpha and p38delta MAPK isoforms by TGF-beta 1 in murine mesangial cells.. 277. 2002
The Saccharomyces cerevisiae LSB6 gene encodes phosphatidylinositol 4-kinase activity.. 277. 2002
Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity.. 277. 2002
T cell-specific expression of the murine CD3delta promoter.. 277. 2002
Bcl-x(L) complements Saccharomyces cerevisiae genes that facilitate the switch from glycolytic to oxidative metabolism.. 277. 2002
Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae.. 277. 2002
Barrier to autointegration factor interacts with the cone-rod homeobox and represses its transactivation function.. 277. 2002
Suppression of nuclear factor-kappa B activity by nitric oxide and hyperoxia in oxygen-resistant cells.. 277. 2002
Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1.. 277. 2002
The CY domain of the Fcgamma RIa alpha-chain (CD64) alters gamma-chain tyrosine-based signaling and phagocytosis.. 277. 2002
Characterization of phosphatidylinositol 3-kinase-dependent phosphorylation of the hydrophobic motif site Thr(389) in p70 S6 kinase 1.. 277. 2002
Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine.. 277. 2002
Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function.. 277. 2002
Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice.. 277. 2002
Functional analysis of the C-terminal extension of telomerase reverse transcriptase. A putative "thumb" domain.. 277. 2002
A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.. 277. 2002
Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor. Identification of a novel "locked-on" phenotype and double revertant mutations.. 277. 2002
Distinct sites on G protein beta gamma subunits regulate different effector functions.. 277. 2002
Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts.. 277. 2002
Molecular cloning and characterization of STAMP1, a highly prostate-specific six transmembrane protein that is overexpressed in prostate cancer.. 277. 2002
Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta.. 277. 2002
Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity.. 277. 2002
Structural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complex.. 277. 2002
Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.. 277. 2002
Rapid nonvesicular transport of sterol between the plasma membrane domains of polarized hepatic cells.. 277. 2002
Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy.. 277. 2002
Transforming growth factor beta activates Smad2 in the absence of receptor endocytosis.. 277. 2002
Changes in glucose transport and water permeability resulting from the T310I pathogenic mutation in Glut1 are consistent with two transport channels per monomer.. 277. 2002
Sauvagine cross-links to the second extracellular loop of the corticotropin-releasing factor type 1 receptor.. 277. 2002
Sex hormone-binding globulin in the human prostate is locally synthesized and may act as an autocrine/paracrine effector.. 277. 2002
Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins.. 277. 2002
Transbilayer movement of dipalmitoylphosphatidylcholine in proteoliposomes reconstituted from detergent extracts of endoplasmic reticulum. Kinetics of transbilayer transport mediated by a single flippase and identification of protein fractions enriched in flippase activity.. 277. 2002
Regulation of peroxisome proliferator-activated receptor-gamma-mediated gene expression. A new mechanism of action for high density lipoprotein.. 277. 2002
Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy.. 277. 2002
Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3.. 277. 2002
Characterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independently.. 277. 2002
Prp43 is an essential RNA-dependent ATPase required for release of lariat-intron from the spliceosome.. 277. 2002
Characterization of dominant-negative mutants of the DEAH-box splicing factors Prp22 and Prp16.. 277. 2002
Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli.. 277. 2002
Exposure of cryptic domains in the alpha 1-chain of laminin-1 by elastase stimulates macrophages urokinase and matrix metalloproteinase-9 expression.. 277. 2002
Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling.. 277. 2002
Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis.. 277. 2002
PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit.. 277. 2002
Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides.. 277. 2002
Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis.. 277. 2001
Phosphatidylcholine transfer protein promotes apolipoprotein A-I-mediated lipid efflux in Chinese hamster ovary cells.. 277. 2001
Functional analysis of conserved residues in the putative "finger" domain of telomerase reverse transcriptase.. 276. 2001
G Protein beta gamma subunits act on the catalytic domain to stimulate Bruton's agammaglobulinemia tyrosine kinase.. 277. 2001
Nerve growth factor activation of Erk-1 and Erk-2 induces matrix metalloproteinase-9 expression in vascular smooth muscle cells.. 277. 2001
Domain structure of the HSC70 cochaperone, HIP.. 277. 2001
Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle.. 277. 2001
Neuritogenesis and the nerve growth factor-induced differentiation of PC-12 cells requires annexin II-mediated plasmin generation.. 276. 2001
UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation.. 276. 2001
Ligand exchange of major histocompatibility complex class II proteins is triggered by H-bond donor groups of small molecules.. 277. 2001
In vivo regulation of oxidative phosphorylation in cells harboring a stop-codon mutation in mitochondrial DNA-encoded cytochrome c oxidase subunit I.. 276. 2001
Residual structure and dynamics in Parkinson's disease-associated mutants of alpha-synuclein.. 276. 2001
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8.. 276. 2001
Role of the PHTH module in protein substrate recognition by Bruton's agammaglobulinemia tyrosine kinase.. 276. 2001
Functional analysis of Streptococcus pneumoniae MurM reveals the region responsible for its specificity in the synthesis of branched cell wall peptides.. 276. 2001
YY1 is a positive regulator of transcription of the Col1a1 gene.. 276. 2001
Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1).. 276. 2001
Role of myosin phosphatase isoforms in cGMP-mediated smooth muscle relaxation.. 276. 2001
Molecular and cellular physiology of the dissociation of atrial natriuretic peptide from guanylyl cyclase a receptors.. 276. 2001
The uptake and degradation of matrix-bound lipoproteins by macrophages require an intact actin Cytoskeleton, Rho family GTPases, and myosin ATPase activity.. 276. 2001
An essential function of Saccharomyces cerevisiae RNA triphosphatase Cet1 is to stabilize RNA guanylyltransferase Ceg1 against thermal inactivation.. 276. 2001
The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor.. 276. 2001
Molecular basis of calmodulin tethering and Ca2+-dependent inactivation of L-type Ca2+ channels.. 276. 2001
Effects of diabetes insipidus mutations on neurophysin folding and function.. 276. 2001
Molecular mass, stoichiometry, and assembly of 20 S particles.. 276. 2001
The length, phosphorylation state, and primary structure of the RNA polymerase II carboxyl-terminal domain dictate interactions with mRNA capping enzymes.. 276. 2001
Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway.. 276. 2001
Transcriptional repression by p53 through direct binding to a novel DNA element.. 276. 2001
Cathepsin S regulates the expression of cathepsin L and the turnover of gamma-interferon-inducible lysosomal thiol reductase in B lymphocytes.. 276. 2001
PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells.. 276. 2001
Ceramide enables fas to cap and kill.. 276. 2001
Functional domains of the yeast splicing factor Prp22p.. 276. 2001
Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation.. 276. 2001
PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2.. 276. 2001
CD95 signaling via ceramide-rich membrane rafts.. 276. 2001
Oxidized low density lipoprotein decreases macrophage expression of scavenger receptor B-I.. 276. 2001
Biochemical and pharmacological criteria define two shedding activities for TRANCE/OPGL that are distinct from the tumor necrosis factor alpha convertase.. 276. 2001
The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor.. 276. 2001
Alternative splicing switches potassium channel sensitivity to protein phosphorylation.. 276. 2001
Disruption of 3-phosphoinositide-dependent kinase 1 (PDK1) signaling by the anti-tumorigenic and anti-proliferative agent n-alpha-tosyl-l-phenylalanyl chloromethyl ketone.. 276. 2001
Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins.. 276. 2001
Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts.. 276. 2001
Kinase suppressor of Ras signals through Thr269 of c-Raf-1.. 276. 2000
Reversal of autocrine and paracrine effects of interleukin 1 (IL-1) in human arthritis by type II IL-1 decoy receptor. Potential for pharmacological intervention.. 275. 2000
BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway.. 275. 2000
Elevated Egr-1 in human atherosclerotic cells transcriptionally represses the transforming growth factor-beta type II receptor.. 275. 2000
Serum withdrawal-induced post-transcriptional stabilization of cyclooxygenase-2 mRNA in MDA-MB-231 mammary carcinoma cells requires the activity of the p38 stress-activated protein kinase.. 275. 2000
Constitutive signaling by Kaposi's sarcoma-associated herpesvirus G-protein-coupled receptor desensitizes calcium mobilization by other receptors.. 276. 2000
The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome.. 276. 2000
Regulation of ROMK1 channels by protein-tyrosine kinase and -tyrosine phosphatase.. 276. 2000
The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton.. 276. 2000
Essential role for caspase-8 in transcription-independent apoptosis triggered by p53.. 275. 2000
Store-operated calcium entry inactivates at the germinal vesicle breakdown stage of Xenopus meiosis.. 275. 2000
Regulation of ribosomal S6 kinase 2 by effectors of the phosphoinositide 3-kinase pathway.. 276. 2000
Ribosomal S6 kinase 2 inhibition by a potent C-terminal repressor domain is relieved by mitogen-activated protein-extracellular signal-regulated kinase kinase-regulated phosphorylation.. 276. 2000
The C-terminal tail of the metabotropic glutamate receptor subtype 7 is necessary but not sufficient for cell surface delivery and polarized targeting in neurons and epithelia.. 276. 2000
Natural ceramide reverses Fas resistance of acid sphingomyelinase(-/-) hepatocytes.. 276. 2000
The Mycobacterium tuberculosis cmaA2 gene encodes a mycolic acid trans-cyclopropane synthetase.. 276. 2000
BRCA1 physically and functionally interacts with ATF1.. 275. 2000
Leptin regulates prothyrotropin-releasing hormone biosynthesis. Evidence for direct and indirect pathways.. 275. 2000
cAMP response element-binding protein-binding protein mediates thyrotropin-releasing hormone signaling on thyrotropin subunit genes.. 275. 2000
The toxoplasma micronemal protein MIC4 is an adhesin composed of six conserved apple domains.. 276. 2000
Isolation and characterization of IIAChb, a soluble protein of the enzyme II complex required for the transport/phosphorylation of N, N'-diacetylchitobiose in Escherichia coli.. 275. 2000
Characterization of the mRNA capping apparatus of Candida albicans.. 276. 2000
Involvement of the helix-loop-helix protein Id-1 in the glucocorticoid regulation of tight junctions in mammary epithelial cells.. 275. 2000
Characterization of the murMN operon involved in the synthesis of branched peptidoglycan peptides in Streptococcus pneumoniae.. 275. 2000
Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways.. 275. 2000
CD95-mediated apoptosis in vivo involves acid sphingomyelinase.. 275. 2000
Phosphorylation of c-Crk II on the negative regulatory Tyr222 mediates nerve growth factor-induced cell spreading and morphogenesis.. 275. 2000
Sequence-specific DNA recognition by the Myb-like domain of plant telomeric protein RTBP1.. 275. 2000
Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains.. 275. 2000
Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death.. 275. 2000
Ca2+-sensitive inactivation and facilitation of L-type Ca2+ channels both depend on specific amino acid residues in a consensus calmodulin-binding motif in the(alpha)1C subunit.. 275. 2000
Potentiation of endogenous fibrinolysis and rescue from lung ischemia/reperfusion injury in interleukin (IL)-10-reconstituted IL-10 null mice.. 275. 2000
Apoptotic signaling through the beta -adrenergic receptor. A new Gs effector pathway.. 275. 2000
The pgdA gene encodes for a peptidoglycan N-acetylglucosamine deacetylase in Streptococcus pneumoniae.. 275. 2000
The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade.. 275. 2000
Epidermal growth factor treatment enhances the kinase activity of kinase suppressor of Ras.. 275. 2000
Selective activation of the glucocorticoid receptor by steroid antagonists in human breast cancer and osteosarcoma cells.. 275. 2000
Effects of incorporation of immunoglobulin G and complement component C1q on uptake and degradation of Alzheimer's disease amyloid fibrils by microglia.. 275. 2000
Characterization of rapid membrane internalization and recycling.. 275. 2000
Genetic analysis of a potential zinc-binding domain of the adenovirus E4 34k protein.. 275. 2000
High affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin II.. 275. 2000
Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways.. 275. 2000
Nerve growth factor-induced neuronal differentiation requires generation of Rac1-regulated reactive oxygen species.. 275. 2000
Structural and functional characterization of platelet receptor-mediated factor VIII binding.. 275. 2000
Tumor necrosis factor employs a protein-tyrosine phosphatase to inhibit activation of KDR and vascular endothelial cell growth factor-induced endothelial cell proliferation.. 275. 2000
Characterization of Staphylococcus aureus cell wall glycan strands, evidence for a new beta-N-acetylglucosaminidase activity.. 275. 2000
CD95(Fas/APO-1) signals ceramide generation independent of the effector stage of apoptosis.. 275. 2000
Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations.. 275. 2000
Role of acidic sphingomyelinase in Fas/CD95-mediated cell death.. 275. 2000
Cell surface display and intracellular trafficking of free glycosylphosphatidylinositols in mammalian cells.. 275. 2000
The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01.. 275. 2000
Benzo[a]pyrene induces the transcription of cyclooxygenase-2 in vascular smooth muscle cells. Evidence for the involvement of extracellular signal-regulated kinase and NF-kappaB.. 275. 2000
Characterization of the insulin-regulated endocytic recycling mechanism in 3T3-L1 adipocytes using a novel reporter molecule.. 275. 2000
Functional association between SLAP-130 and SLP-76 in Jurkat T cells.. 275. 2000
Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation.. 275. 2000
Selective activation of MAPK(erk1/2) by laminin-1 peptide alpha1:Ser(2091)-Arg(2108) regulates macrophage degradative phenotype.. 275. 2000
Thyroid hormone-independent interaction between the thyroid hormone receptor beta2 amino terminus and coactivators.. 275. 2000
Transforming growth factor-beta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gamma.. 275. 2000
Activation of c-Ha-Ras by nitric oxide modulates survival responsiveness in neuronal PC12 cells.. 274. 1999
Deacylation of lipopolysaccharide in whole Escherichia coli during destruction by cellular and extracellular components of a rabbit peritoneal inflammatory exudate.. 274. 1999
Tumor cell viability in clear cell sarcoma requires DNA binding activity of the EWS/ATF1 fusion protein.. 274. 1999
Generation of the amyloid-beta peptide N terminus in Saccharomyces cerevisiae expressing human Alzheimer's amyloid-beta precursor protein.. 274. 1999
Purification of an EH domain-binding protein from rat brain that modulates the gating of the rat ether-à-go-go channel.. 274. 1999
Unique cellular events occurring during the initial interaction of macrophages with matrix-retained or methylated aggregated low density lipoprotein (LDL). Prolonged cell-surface contact during which ldl-cholesteryl ester hydrolysis exceeds ldl protein degradation.. 274. 1999
Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells.. 274. 1999
Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.. 274. 1999
The cytoplasmic domain of human FcgammaRIa alters the functional properties of the FcgammaRI.gamma-chain receptor complex.. 274. 1999
Mutational analyses of yeast RNA triphosphatases highlight a common mechanism of metal-dependent NTP hydrolysis and a means of targeting enzymes to pre-mRNAs in vivo by fusion to the guanylyltransferase component of the capping apparatus.. 274. 1999
The functional microdomain in transmembrane helices 2 and 7 regulates expression, activation, and coupling pathways of the gonadotropin-releasing hormone receptor.. 274. 1999
Direct interaction of proliferating cell nuclear antigen with the p125 catalytic subunit of mammalian DNA polymerase delta.. 274. 1999
The targeted disruption of both alleles of RARbeta(2) in F9 cells results in the loss of retinoic acid-associated growth arrest.. 274. 1999
Caveolin-2 localizes to the golgi complex but redistributes to plasma membrane, caveolae, and rafts when co-expressed with caveolin-1.. 274. 1999
Cooperative assembly of androgen receptor into a nucleoprotein complex that regulates the prostate-specific antigen enhancer.. 274. 1999
Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane. Retention of caveolin-2 at the level of the golgi complex.. 274. 1999
Insulin activates protein kinases C-zeta and C-lambda by an autophosphorylation-dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes.. 274. 1999
Involvement of protein kinase Cepsilon (PKCepsilon) in thyroid cell death. A truncated chimeric PKCepsilon cloned from a thyroid cancer cell line protects thyroid cells from apoptosis.. 274. 1999
A conserved domain of yeast RNA triphosphatase flanking the catalytic core regulates self-association and interaction with the guanylyltransferase component of the mRNA capping apparatus.. 274. 1999
Potentiation of human estrogen receptor alpha transcriptional activation through phosphorylation of serines 104 and 106 by the cyclin A-CDK2 complex.. 274. 1999
Inactivation of the inhibitory kappaB protein kinase/nuclear factor kappaB pathway by Par-4 expression potentiates tumor necrosis factor alpha-induced apoptosis.. 274. 1999
A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism.. 274. 1999
Inactivated pbp4 in highly glycopeptide-resistant laboratory mutants of Staphylococcus aureus.. 274. 1999
Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase.. 274. 1999
A cell-free assay for glycosylphosphatidylinositol anchoring in African trypanosomes. Demonstration of a transamidation reaction mechanism.. 274. 1999
A mutation in the MSH6 subunit of the Saccharomyces cerevisiae MSH2-MSH6 complex disrupts mismatch recognition.. 274. 1999
Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes.. 274. 1999
SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity.. 274. 1999
Calreticulin affects focal contact-dependent but not close contact-dependent cell-substratum adhesion.. 274. 1999
Segregation of glycosylphosphatidylinositol biosynthetic reactions in a subcompartment of the endoplasmic reticulum.. 274. 1999
Nitric oxide inhibits thrombin receptor-activating peptide-induced phosphoinositide 3-kinase activity in human platelets.. 274. 1999
Decreased intracellular superoxide levels activate Sindbis virus-induced apoptosis.. 274. 1999
Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival.. 274. 1999
Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells.. 274. 1999
Fyn kinase-directed activation of SH2 domain-containing protein-tyrosine phosphatase SHP-2 by Gi protein-coupled receptors in Madin-Darby canine kidney cells.. 274. 1999
Cleavage of zetaPKC but not lambda/iotaPKC by caspase-3 during UV-induced apoptosis.. 274. 1999
Inhibition of cyclooxygenase-2 gene expression by p53.. 274. 1999
Intracellular pH and multidrug resistance regulate complement-mediated cytotoxicity of nucleated human cells.. 274. 1999
Transforming growth factor beta1 rescues serum deprivation-induced apoptosis via the mitogen-activated protein kinase (MAPK) pathway in macrophages.. 274. 1999
The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling.. 274. 1999
Oligomycin induces a decrease in the cellular content of a pathogenic mutation in the human mitochondrial ATPase 6 gene.. 274. 1999
Retinoids inhibit interleukin-12 production in macrophages through physical associations of retinoid X receptor and NFkappaB.. 274. 1999
pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells.. 274. 1999
Solvent-exposed residues in the Tet repressor (TetR) four-helix bundle contribute to subunit recognition and dimer stability.. 274. 1999
The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains.. 274. 1999
Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets.. 274. 1999
Activation of nuclear factor of activated T cells-(NFAT) and activating protein 1 (AP-1) by oncogenic 70Z Cbl requires an intact phosphotyrosine binding domain but not Crk(L) or p85 phosphatidylinositol 3-kinase association.. 274. 1999
Adenophostin A and inositol 1,4,5-trisphosphate differentially activate Cl- currents in Xenopus oocytes because of disparate Ca2+ release kinetics.. 274. 1999
Heat-induced oligomerization of the molecular chaperone Hsp90. Inhibition by ATP and geldanamycin and activation by transition metal oxyanions.. 274. 1999
Identification and purification of the rat liver Golgi membrane UDP-N-acetylgalactosamine transporter.. 274. 1999
Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity.. 274. 1999
Heterologous expression and functional characterization of a mouse renal organic anion transporter in mammalian cells.. 274. 1999
Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation.. 274. 1999
Hyaluronan fragments synergize with interferon-gamma to induce the C-X-C chemokines mig and interferon-inducible protein-10 in mouse macrophages.. 273. 1998
Recombinant glutathione S-transferase/CD36 fusion proteins define an oxidized low density lipoprotein-binding domain.. 273. 1998
Substrate specificity and kinetic mechanism of the insect sulfotransferase, retinol dehydratase.. 273. 1998
The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding.. 273. 1998
Identification of TaqI endonuclease active site residues by Fe2+-mediated oxidative cleavage.. 273. 1998
Macrophage formation of angiostatin during inflammation. A byproduct of the activation of plasminogen.. 273. 1998
BAD enables ceramide to signal apoptosis via Ras and Raf-1.. 273. 1998
Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone.. 273. 1998
Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway.. 273. 1998
Three isoforms of a hepatocyte nuclear factor-4 transcription factor with tissue- and stage-specific expression in the adult mosquito.. 273. 1998
Ceramide generation by the Reaper protein is not blocked by the caspase inhibitor, p35.. 273. 1998
gamma-glutamyl leukotrienase, a gamma-glutamyl transpeptidase gene family member, is expressed primarily in spleen.. 273. 1998
SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors.. 273. 1998
Intracellular maturation of the mouse metalloprotease disintegrin MDC15.. 273. 1998
Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130.. 273. 1998
Mitotic Raf-1 is stimulated independently of Ras and is active in the cytoplasm.. 273. 1998
p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.. 273. 1998
GTP cyclohydrolase I inhibition by the prototypic inhibitor 2, 4-diamino-6-hydroxypyrimidine. Mechanisms and unanticipated role of GTP cyclohydrolase I feedback regulatory protein.. 273. 1998
A farnesyl-protein transferase inhibitor induces p21 expression and G1 block in p53 wild type tumor cells.. 273. 1998
Induction of acute translational response genes by homocysteine. Elongation factors-1alpha, -beta, and -delta.. 273. 1998
Localization of Tctex-1, a cytoplasmic dynein light chain, to the Golgi apparatus and evidence for dynein complex heterogeneity.. 273. 1998
Identification of an insulin-responsive, slow endocytic recycling mechanism in Chinese hamster ovary cells.. 273. 1998
A revised model for the oligomeric state of the N-ethylmaleimide-sensitive fusion protein, NSF.. 273. 1998
Analysis of the Gs/mitogen-activated protein kinase pathway in mutant S49 cells.. 273. 1998
Caenorhabditis elegans contains two distinct acid sphingomyelinases.. 273. 1998
Phosphorylation and inhibition of rat glucocorticoid receptor transcriptional activation by glycogen synthase kinase-3 (GSK-3). Species-specific differences between human and rat glucocorticoid receptor signaling as revealed through GSK-3 phosphorylation.. 273. 1998
Insulin receptor-mediated dissociation of Grb2 from Sos involves phosphorylation of Sos by kinase(s) other than extracellular signal-regulated kinase.. 273. 1998
The transferrin receptor cytoplasmic domain determines its rate of transport through the biosynthetic pathway and its susceptibility to cleavage early in the pathway.. 273. 1998
Activation of gene expression by a ligand-induced conformational change of a protein-DNA complex.. 273. 1998
Immunolocalization of acyl-coenzyme A:cholesterol O-acyltransferase in macrophages.. 273. 1998
Functional microdomains in G-protein-coupled receptors. The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor.. 273. 1998
The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway.. 273. 1998
Visualization of dynamic trafficking of a protein kinase C betaII/green fluorescent protein conjugate reveals differences in G protein-coupled receptor activation and desensitization.. 273. 1998
The guanylyltransferase domain of mammalian mRNA capping enzyme binds to the phosphorylated carboxyl-terminal domain of RNA polymerase II.. 273. 1998
Tissue plasminogen activator binding to the annexin II tail domain. Direct modulation by homocysteine.. 273. 1998
Interactions of the borna disease virus P, N, and X proteins and their functional implications.. 273. 1998
The epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeleton.. 273. 1998
The epidermal growth factor receptor associates with and recruits phosphatidylinositol 3-kinase to the platelet-derived growth factor beta receptor.. 273. 1998
Synergistic regulation of the human interleukin-12 p40 promoter by NFkappaB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages.. 273. 1998
Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways.. 273. 1998
Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins.. 273. 1998
Neurofilament (NF) assembly; divergent characteristics of human and rodent NF-L subunits.. 273. 1998
Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells.. 273. 1998
Dihydroxy bile acids activate the transcription of cyclooxygenase-2.. 273. 1998
Ligand binding to macrophage scavenger receptor-A induces urokinase-type plasminogen activator expression by a protein kinase-dependent signaling pathway.. 273. 1998
Aortic smooth muscle cells interact with tenascin-C through its fibrinogen-like domain.. 272. 1997
A transcription activator with restricted tissue distribution regulates cell-specific expression of alpha1(XI) collagen.. 272. 1997
Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells.. 272. 1997
Lysophosphatidylcholine regulates cationic amino acid transport and metabolism in vascular smooth muscle cells. Role in polyamine biosynthesis.. 272. 1997
Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking.. 272. 1997
Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport.. 272. 1997
An autoinhibitory control element defines calcium-regulated isoforms of nitric oxide synthase.. 272. 1997
Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein.. 272. 1997
Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells.. 272. 1997
Structural characterization of an abnormally cross-linked muropeptide dimer that is accumulated in the peptidoglycan of methicillin- and cefotaxime-resistant mutants of Staphylococcus aureus.. 272. 1997
Cloning and characterization of a human STE20-like protein kinase with unusual cofactor requirements.. 272. 1997
Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein.. 272. 1997
The mechanism by which heparin promotes the inhibition of coagulation factor XIa by protease nexin-2.. 272. 1997
A unique role of the beta-2 thyroid hormone receptor isoform in negative regulation by thyroid hormone. Mapping of a novel amino-terminal domain important for ligand-independent activation.. 272. 1997
Native and modified low density lipoproteins increase the functional expression of the macrophage class B scavenger receptor, CD36.. 272. 1997
T cell receptor-induced phosphorylation of Sos requires activity of CD45, Lck, and protein kinase C, but not ERK.. 272. 1997
Isoform-specific interaction of the myosin-binding proteins (MyBPs) with skeletal and cardiac myosin is a property of the C-terminal immunoglobulin domain.. 272. 1997
Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgamma1 and -2 isoforms and influence of insulin.. 272. 1997
ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks.. 272. 1997
Genetic evidence for a tyrosine kinase cascade preceding the mitogen-activated protein kinase cascade in vertebrate G protein signaling.. 272. 1997
Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization.. 272. 1997
Argininosuccinate synthetase overexpression in vascular smooth muscle cells potentiates immunostimulant-induced NO production.. 272. 1997
Differential modulation of neuron survival during development by nerve growth factor binding to the p75 neurotrophin receptor.. 272. 1997
Platelet endothelial cell adhesion molecule-1 is phosphorylatable by c-Src, binds Src-Src homology 2 domain, and exhibits immunoreceptor tyrosine-based activation motif-like properties.. 272. 1997
Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling.. 272. 1997
AM67, a secretory component of the guinea pig sperm acrosomal matrix, is related to mouse sperm protein sp56 and the complement component 4-binding proteins.. 272. 1997
Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases.. 272. 1997
Identification and characterization of a novel Ets-2-related nuclear complex implicated in the activation of the human interleukin-12 p40 gene promoter.. 272. 1997
Role of laminin in matrix induction of macrophage urokinase-type plasminogen activator and 92-kDa metalloproteinase expression.. 272. 1997
The COOH-terminal peptide binding domain is essential for self-association of the molecular chaperone HSC70.. 272. 1997
Mutations in the second cytoplasmic loop of the rat parathyroid hormone (PTH)/PTH-related protein receptor result in selective loss of PTH-stimulated phospholipase C activity.. 272. 1997
The role of the variable region in Tet repressor for inducibility by tetracycline.. 272. 1997
Functional antagonism between CCAAT/Enhancer binding protein-alpha and peroxisome proliferator-activated receptor-gamma on the leptin promoter.. 272. 1997
A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction.. 272. 1997
Nuclear factor interleukin 6 motifs mediate tissue-specific gene transcription in hypoxia.. 272. 1997
The neural cell adhesion molecule expresses a tyrosine-independent basolateral sorting signal.. 272. 1997
Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility.. 272. 1997
Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport.. 272. 1997
Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).. 272. 1997
Retinoic acid-responsive enhancers located 3' of the Hox A and Hox B homeobox gene clusters. Functional analysis.. 272. 1997
Identification and characterization of a nuclease specific for the 3' end of the U6 small nuclear RNA.. 272. 1997
SLP-76 is a substrate of the high affinity IgE receptor-stimulated protein tyrosine kinases in rat basophilic leukemia cells.. 272. 1997
Transcription termination by vaccinia RNA polymerase entails recognition of specific phosphates in the nascent RNA.. 272. 1997
A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization.. 271. 1996
Identification and characterization of CD39/vascular ATP diphosphohydrolase.. 271. 1996
The bZIP transcription factor Nrl stimulates rhodopsin promoter activity in primary retinal cell cultures.. 271. 1996
An ATPase component of the transcription elongation complex is required for factor-dependent transcription termination by vaccinia RNA polymerase.. 271. 1996
Endoplasmic reticulum form of calreticulin modulates glucocorticoid-sensitive gene expression.. 271. 1996
Effector cell protease receptor-1 is a vascular receptor for coagulation factor Xa.. 271. 1996
Function of nuclear co-repressor protein on thyroid hormone response elements is regulated by the receptor A/B domain.. 271. 1996
Inhibition of tumor necrosis factor signal transduction in endothelial cells by dimethylaminopurine.. 271. 1996
Gbeta subunit interacts with a peptide encoding region 956-982 of adenylyl cyclase 2. Cross-linking of the peptide to free Gbetagamma but not the heterotrimer.. 271. 1996
Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53.. 271. 1996
Leucine-responsive regulatory protein-DNA interactions in the leader region of the ilvGMEDA operon of Escherichia coli.. 271. 1996
Superoxide-mediated actin response in post-hypoxic endothelial cells.. 271. 1996
Selectivity of the renal collecting duct water channel aquaporin-3.. 271. 1996
ATP-facilitated chromatin assembly with a nucleoplasmin-like protein from Drosophila melanogaster.. 271. 1996
Adenylyl cyclase G, an osmosensor controlling germination of Dictyostelium spores.. 271. 1996
The serine protease inhibitors, tosylphenylalanine chloromethyl ketone and tosyllysine chloromethyl ketone, potently inhibit pp70s6k activation.. 271. 1996
The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene.. 271. 1996
Inducible nitric oxide synthase requires both the canonical calmodulin-binding domain and additional sequences in order to bind calmodulin and produce nitric oxide in the absence of free Ca2+.. 271. 1996
Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase.. 271. 1996
Interaction of the fibrinolytic receptor, annexin II, with the endothelial cell surface. Essential role of endonexin repeat 2.. 271. 1996
The carboxyl terminus of GLUT4 contains a serine-leucine-leucine sequence that functions as a potent internalization motif in Chinese hamster ovary cells.. 271. 1996
Factor-dependent release of nascent RNA by ternary complexes of vaccinia RNA polymerase.. 271. 1996
Glucocorticoid-mediated repression of NFkappaB activity in endothelial cells does not involve induction of IkappaBalpha synthesis.. 271. 1996
Effect of nucleotides, peptides, and unfolded proteins on the self-association of the molecular chaperone HSC70.. 271. 1996
Cross-talk between different enhancer elements during mitogenic induction of the human stromelysin-1 gene.. 271. 1996
Reversible desensitization of inositol trisphosphate-induced calcium release provides a mechanism for repetitive calcium spikes.. 271. 1996
Involvement of Gs and Gi proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C.. 271. 1996
Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase.. 271. 1996
Purification, cloning, and bacterial expression of retinol dehydratase from Spodoptera frugiperda.. 271. 1996
Phosphatidylinositol hydrolysis by Trypanosoma brucei glycosylphosphatidylinositol phospholipase C.. 271. 1996
An analysis of retinoic acid-induced gene expression and metabolism in AB1 embryonic stem cells.. 271. 1996
Mapping the binding site pocket of the serotonin 5-Hydroxytryptamine2A receptor. Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin.. 271. 1996
The distal pathway of lipoprotein-induced cholesterol esterification, but not sphingomyelinase-induced cholesterol esterification, is energy-dependent.. 271. 1996
Multiple pathways for vacuolar sorting of yeast proteinase A.. 271. 1996
Platelet-derived growth factor regulates vascular smooth muscle cell proliferation by inducing cationic amino acid transporter gene expression.. 271. 1996
Wortmannin-sensitive trafficking pathways in Chinese hamster ovary cells. Differential effects on endocytosis and lysosomal sorting.. 271. 1996
Molecular determinants of the clearance function of type C receptors of natriuretic peptides.. 271. 1996
Overexpression of calreticulin increases intracellular Ca2+ storage and decreases store-operated Ca2+ influx.. 271. 1996
Genistein is a natural inhibitor of hexose and dehydroascorbic acid transport through the glucose transporter, GLUT1.. 271. 1996
Epidermal growth factor receptor targeting prevents uncoupling of the Grb2-SOS complex.. 271. 1996
Inhibition of macrophage scavenger receptor activity by tumor necrosis factor-alpha is transcriptionally and post-transcriptionally regulated.. 271. 1996
Murine laminin B1 gene regulation during the retinoic acid- and dibutyryl cyclic AMP-induced differentiation of embryonic F9 teratocarcinoma stem cells.. 271. 1996
Cloning and characterization of the promoter for a potassium channel expressed in high frequency firing neurons.. 271. 1996
Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence.. 271. 1996
13C and 31P NMR investigation of effect of 6-aminonicotinamide on metabolism of RIF-1 tumor cells in vitro.. 271. 1996
Stimulus-dependent phosphorylation of MacMARCKS, a protein kinase C substrate, in nerve termini and PC12 cells.. 271. 1996
Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells.. 270. 1995
Identification of the sites of interaction between lymphocyte phosphatase-associated phosphoprotein (LPAP) and CD45.. 270. 1995
A conserved downstream element defines a new class of RNA polymerase II promoters.. 270. 1995
Identification of a novel repressive element in the proximal lck promoter.. 270. 1995
Association of sorcin with the cardiac ryanodine receptor.. 270. 1995
Studies of transferrin recycling reconstituted in streptolysin O permeabilized Chinese hamster ovary cells.. 270. 1995
Nonpolarized distribution of glycosylphosphatidylinositols in the plasma membrane of polarized Madin-Darby canine kidney cells.. 270. 1995
Quasi-native chaperonin-bound intermediates in facilitated protein folding.. 270. 1995
ATP-dependent processivity of a telomerase activity from Saccharomyces cerevisiae.. 270. 1995
Role of COOH-terminal phosphorylation in the regulation of casein kinase I delta.. 270. 1995
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.. 270. 1995
Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C.. 270. 1995
Inhibition of capillary morphogenesis and associated apoptosis by dominant negative mutant transforming growth factor-beta receptors.. 270. 1995
Cyclic adenosine monophosphate can convert epidermal growth factor into a differentiating factor in neuronal cells.. 270. 1995
v-Crk modulation of growth factor-induced PC12 cell differentiation involves the Src homology 2 domain of v-Crk and sustained activation of the Ras/mitogen-activated protein kinase pathway.. 270. 1995
Altered cholesterol trafficking in herpesvirus-infected arterial cells. Evidence for viral protein kinase-mediated cholesterol accumulation.. 270. 1995
13,14-Dihydroxy-retinol, a new bioactive retinol metabolite.. 270. 1995
A locus of the gonadotropin-releasing hormone receptor that differentiates agonist and antagonist binding sites.. 270. 1995
Herbimycin A induces the 20 S proteasome- and ubiquitin-dependent degradation of receptor tyrosine kinases.. 270. 1995
Related contribution of specific helix 2 and 7 residues to conformational activation of the serotonin 5-HT2A receptor.. 270. 1995
Identification of heterogeneous ribonucleoprotein A1 as a novel substrate for protein kinase C zeta.. 270. 1995
Gamma chain-associated cytokine receptors signal through distinct transducing factors.. 270. 1995
Ligand-independent and -dependent functions of thyroid hormone receptor isoforms depend upon their distinct amino termini.. 270. 1995
Dimerization of the TATA binding protein.. 270. 1995
Evidence for functional binding and stable sliding of the TATA binding protein on nonspecific DNA.. 270. 1995
Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes.. 270. 1995
A cytoplasmic tyrosine is essential for the basolateral localization of mutants of the human nerve growth factor receptor in Madin-Darby canine kidney cells.. 270. 1995
SH3 domain-mediated interaction of dystroglycan and Grb2.. 270. 1995
The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling.. 270. 1995
An internalization motif is created in the cytoplasmic domain of the transferrin receptor by substitution of a tyrosine at the first position of a predicted tight turn.. 270. 1995
Identification of functional domains of adenylyl cyclase using in vivo chimeras.. 270. 1995
Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells.. 270. 1995
Mouse mammary tumors express elevated levels of RNA encoding the murine homology of SKY, a putative receptor tyrosine kinase.. 270. 1995
Activation of the TSG-6 gene by NF-IL6 requires two adjacent NF-IL6 binding sites.. 270. 1995
Thyroid hormone influences the maturation of apolipoprotein A-I messenger RNA in rat liver.. 270. 1995
Overlapping pathways mediate the opposing actions of tumor necrosis factor-alpha and transforming growth factor-beta on alpha 2(I) collagen gene transcription.. 270. 1995
Effects of apoprotein E on intracellular metabolism of model triglyceride-rich particles are distinct from effects on cell particle uptake.. 270. 1995
Characterization of an autoinhibitory domain in human mitogen-activated protein kinase-activated protein kinase 2.. 270. 1995
A novel C-terminal domain in the thyroid hormone receptor selectively mediates thyroid hormone inhibition.. 269. 1994
Apexin, an acrosomal pentaxin.. 269. 1994
Regulation of macrophage receptor-bound plasmin by autoproteolysis.. 269. 1994
Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells.. 269. 1994
Evidence for the in vitro and in vivo interaction of Ras with protein kinase C zeta.. 269. 1994
Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.. 269. 1994
c-Jun represses transcription of the human chorionic gonadotropin alpha and beta genes through distinct types of CREs.. 269. 1994
Adenovirus-mediated gene transfer of rat apolipoprotein B mRNA-editing protein in mice virtually eliminates apolipoprotein B-100 and normal low density lipoprotein production.. 269. 1994
Insulin receptor substrate-1 mediates phosphatidylinositol 3'-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation.. 269. 1994
Interaction of TaqI endonuclease with the phosphate backbone. Effects of stereospecific phosphate modification.. 269. 1994
LPAP, a novel 32-kDa phosphoprotein that interacts with CD45 in human lymphocytes.. 269. 1994
Carboxyl terminus of inducible nitric oxide synthase. Contribution to NADPH binding and enzymatic activity.. 269. 1994
Reduced methicillin resistance in a new Staphylococcus aureus transposon mutant that incorporates muramyl dipeptides into the cell wall peptidoglycan.. 269. 1994
L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases.. 269. 1994
Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine.. 269. 1994
GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.. 269. 1994
The actin cytoskeleton is important for the stimulation of cholesterol esterification by atherogenic lipoproteins in macrophages.. 269. 1994
In vivo association of Grb2 with pp116, a substrate of the T cell antigen receptor-activated protein tyrosine kinase.. 269. 1994
An endothelial cell receptor for plasminogen/tissue plasminogen activator (t-PA). II. Annexin II-mediated enhancement of t-PA-dependent plasminogen activation.. 269. 1994
An endothelial cell receptor for plasminogen/tissue plasminogen activator. I. Identity with annexin II.. 269. 1994
A nonexchangeable apolipoprotein E peptide that mediates binding to the low density lipoprotein receptor.. 269. 1994
Cloning and characterization of alternatively spliced isoforms of rat tenascin. Platelet-derived growth factor-BB markedly stimulates expression of spliced variants of tenascin mRNA in arterial smooth muscle cells.. 269. 1994
Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase.. 269. 1994
Bacterial lipopolysaccharide has structural similarity to ceramide and stimulates ceramide-activated protein kinase in myeloid cells.. 269. 1994
Characterization of thrombomodulin expression in response to retinoic acid and identification of a retinoic acid response element in the human thrombomodulin gene.. 269. 1994
A role for the H4 subunit of vaccinia RNA polymerase in transcription initiation at a viral early promoter.. 269. 1994
Helix sense of gramicidin channels as a "nonlocal" function of the primary sequence.. 269. 1994
Argininosuccinate synthetase mRNA and activity are induced by immunostimulants in vascular smooth muscle. Role in the regeneration or arginine for nitric oxide synthesis.. 269. 1994
DNA strand exchange in the absence of homologous pairing.. 269. 1994
Zeta PKC plays a critical role during stromelysin promoter activation by platelet-derived growth factor through a novel palindromic element.. 269. 1994
Basic fibroblast growth factor-induced low density lipoprotein receptor transcription and surface expression. Signal transduction pathways mediated by the bFGF receptor tyrosine kinase.. 269. 1994
Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.. 269. 1994
High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors.. 269. 1994
Soluble beta 2-microglobulin-free class I heavy chains are released from the surface of activated and leukemia cells by a metalloprotease.. 269. 1994
Thyrotropin-releasing hormone (TRH) receptor number determines the size of the TRH-responsive phosphoinositide pool. Demonstration using controlled expression of TRH receptors by adenovirus mediated gene transfer.. 269. 1994
Regulation of endocytic trafficking and acidification are independent of the cystic fibrosis transmembrane regulator.. 269. 1994
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.. 269. 1994
MgATP-induced conformational changes in the iron protein from Azotobacter vinelandii, as studied by small-angle x-ray scattering.. 269. 1994
Renaturation and tumor necrosis factor-alpha stimulation of a 97-kDa ceramide-activated protein kinase.. 269. 1994
Activation of keratin 19 gene expression by a 3' enhancer containing an AP1 site.. 269. 1994
Differential regulation of the two xGATA-1 genes during Xenopus development.. 269. 1994
The REC1 gene of Ustilago maydis involved in the cellular response to DNA damage encodes an exonuclease.. 269. 1994
Rhodopsin mutations responsible for autosomal dominant retinitis pigmentosa. Clustering of functional classes along the polypeptide chain.. 268. 1993
The peptidoglycan composition of a Staphylococcus aureus mutant selected for reduced methicillin resistance.. 268. 1993
Detection and characterization of ceramide-1-phosphate phosphatase activity in rat liver plasma membrane.. 268. 1993
Small-angle x-ray scattering studies of the iron-molybdenum cofactor from Azotobacter vinelandii nitrogenase.. 268. 1993
Region-specific methylation of the parathyroid hormone-related peptide gene determines its expression in human renal carcinoma cell lines.. 268. 1993
Substrate recognition by ceramide-activated protein kinase. Evidence that kinase activity is proline-directed.. 268. 1993
Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells.. 268. 1993
Cytokine regulation of low density lipoprotein receptor gene transcription in HepG2 cells.. 268. 1993
Differential expression and ligand binding properties of tumor necrosis factor receptor chimeric mutants.. 268. 1993
Altered beta-adrenergic receptor-stimulated cAMP formation in cultured skin fibroblasts from Alzheimer donors.. 268. 1993
Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells.. 268. 1993
Failure of rapamycin to block proliferation once resting cells have entered the cell cycle despite inactivation of p70 S6 kinase.. 268. 1993
Macrophage and foam cell release of matrix-bound growth factors. Role of plasminogen activation.. 268. 1993
CD45-associated kinase activity requires lck but not T cell receptor expression in the Jurkat T cell line.. 268. 1993
Induction of basic fibroblast growth factor mRNA and protein synthesis in smooth muscle cells by cholesteryl ester enrichment and 25-hydroxycholesterol.. 268. 1993
Ricin-resistant Madin-Darby canine kidney cells missort a major endogenous apical sialoglycoprotein.. 268. 1993
Molecular cloning, expression, and characterization of a 49-kilodalton casein kinase I isoform from rat testis.. 268. 1993
Purification and characterization of a nuclear DNA-binding factor complex containing topoisomerase II and chromosome scaffold protein 2.. 268. 1993
Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events.. 268. 1993
Complete primary structure of a sea urchin type IV collagen alpha chain and analysis of the 5' end of its gene.. 268. 1993
The VPS16 gene product associates with a sedimentable protein complex and is essential for vacuolar protein sorting in yeast.. 268. 1993
Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1.. 268. 1993
High density lipoprotein interconversions in rat and man as assessed with a novel nontransferable apolipopeptide.. 268. 1993
Molecular cloning of chicken myosin-binding protein (MyBP) H (86-kDa protein) reveals extensive homology with MyBP-C (C-protein) with conserved immunoglobulin C2 and fibronectin type III motifs.. 268. 1993
Protein kinase C is activated in platelets subjected to pathological shear stress.. 268. 1993
Adenovirus-mediated augmentation of cell transfection with unmodified plasmid vectors.. 268. 1993
Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes.. 268. 1993
Angiotensin II regulates parathyroid hormone-related protein expression in cultured rat aortic smooth muscle cells through transcriptional and post-transcriptional mechanisms.. 268. 1993
Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro.. 268. 1993
Characterization of the p150,95 leukocyte integrin alpha subunit (CD11c) gene promoter. Identification of cis-acting elements.. 268. 1993
Alternative splicing of intron 23 of the human cystic fibrosis transmembrane conductance regulator gene resulting in a novel exon and transcript coding for a shortened intracytoplasmic C terminus.. 268. 1993
The yeast VPS17 gene encodes a membrane-associated protein required for the sorting of soluble vacuolar hydrolases.. 268. 1993
Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle.. 267. 1992
Transforming growth factor-beta up-regulates low density lipoprotein receptor-mediated cholesterol metabolism in vascular smooth muscle cells.. 267. 1992
Identification of an upstream regulatory region essential for cell type-specific transcription of the pro-alpha 2(V) collagen gene (COL5A2).. 267. 1992
Complexity of ethanolamine phosphate addition in the biosynthesis of glycosylphosphatidylinositol anchors in mammalian cells.. 267. 1992
A rise and fall in 1,2-diacylglycerol content signal hexamethylene bisacetamide-induced erythropoiesis.. 267. 1992
Angiotensin II regulates tenascin gene expression in vascular smooth muscle cells.. 267. 1992
Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10.. 267. 1992
The level of CRABP-I expression influences the amounts and types of all-trans-retinoic acid metabolites in F9 teratocarcinoma stem cells.. 267. 1992
Transgenic mice expressing full-length human apolipoprotein B-100. Full-length human apolipoprotein B mRNA is essentially not edited in mouse intestine or liver.. 267. 1992
Inhibition of mitogen-induced c-fos expression in melanoma cells by retinoic acid involves the serum response element.. 267. 1992
Transcriptional regulation by a point mutant of adenovirus-2 E1a product lacking DNA binding activity.. 267. 1992
Recombinant interleukin-2 analogs. Dynamic probes for receptor structure.. 267. 1992
Red 25, a protein that binds specifically to the sterol regulatory region in the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase.. 267. 1992
Retinoic acid regulates both expression of the nerve growth factor receptor and sensitivity to nerve growth factor.. 267. 1992
Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C.. 267. 1992
Phosphatidylethanolamine is the donor of the ethanolamine residue linking a glycosylphosphatidylinositol anchor to protein.. 267. 1992
Dynamics of atrial natriuretic factor-guanylate cyclase receptors and receptor-ligand complexes in cultured glomerular mesangial and renomedullary interstitial cells.. 267. 1992
Peptidoglycan composition in heterogeneous Tn551 mutants of a methicillin-resistant Staphylococcus aureus strain.. 267. 1992
Peptidoglycan composition of a highly methicillin-resistant Staphylococcus aureus strain. The role of penicillin binding protein 2A.. 267. 1992
A synthetic ceramide analog, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, selectively inhibits adherence during macrophage differentiation of human leukemia cells.. 267. 1992
Characterization of steady state, single-turnover, and binding kinetics of the TaqI restriction endonuclease.. 267. 1992
DNA recognition of base analogue and chemically modified substrates by the TaqI restriction endonuclease.. 267. 1992
Varied poly(A) site efficiency in the adenovirus major late transcription unit.. 267. 1992
Developmental variation of glycosylphosphatidylinositol membrane anchors in Trypanosoma brucei. In vitro biosynthesis of intermediates in the construction of the GPI anchor of the major procyclic surface glycoprotein.. 267. 1992
Ceramide is a competitive inhibitor of diacylglycerol kinase in vitro and in intact human leukemia (HL-60) cells.. 267. 1992
Galactose-containing glycosylphosphatidylinositols in Trypanosoma brucei.. 267. 1992
Complete putative metal finger and leucine zipper structures of CRE-BP1 are required for the E1A-induced trans-activation.. 266. 1991
Protein kinase C-independent expression of stromelysin by platelet-derived growth factor, ras oncogene, and phosphatidylcholine-hydrolyzing phospholipase C.. 266. 1991
Stimulation of macrophage urokinase expression by polyanions is protein kinase C-dependent and requires protein and RNA synthesis.. 266. 1991
The endothelial cell tissue plasminogen activator receptor. Specific interaction with plasminogen.. 266. 1991
Locating a low density lipoprotein-targeting domain of human apolipoprotein B-100 by expressing a minigene construct in transgenic mice.. 266. 1991
Interleukin-8 gene expression in human bronchial epithelial cells.. 266. 1991
The mevalonate pathway in the bloodstream form of Trypanosoma brucei. Identification of dolichols containing 11 and 12 isoprene residues.. 266. 1991
Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils.. 266. 1991
Respiratory tract gene transfer. Transplantation of genetically modified T-lymphocytes directly to the respiratory epithelial surface.. 266. 1991
Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells.. 266. 1991
Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action.. 266. 1991
Nerve growth factor-induced neuronal differentiation after dominant repression of both type I and type II cAMP-dependent protein kinase activities.. 266. 1991
Clearance of chylomicron remnants by the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.. 266. 1991
Sphingomyelin synthesis is involved in adherence during macrophage differentiation of HL-60 cells.. 266. 1991
Down-regulation of cystic fibrosis gene mRNA transcript levels and induction of the cystic fibrosis chloride secretory phenotype in epithelial cells by phorbol ester.. 266. 1991
The cystic fibrosis gene has a "housekeeping"-type promoter and is expressed at low levels in cells of epithelial origin.. 266. 1991
Developmental variation of glycosylphosphatidylinositol membrane anchors in Trypanosoma brucei. Identification of a candidate biosynthetic precursor of the glycosylphosphatidylinositol anchor of the major procyclic stage surface glycoprotein.. 266. 1991
Requirement of phospholipase C-catalyzed hydrolysis of phosphatidylcholine for maturation of Xenopus laevis oocytes in response to insulin and ras p21.. 266. 1991
N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine.. 266. 1991
Dissociation of protein kinase C activation and sn-1,2-diacylglycerol formation. Comparison of phosphatidylinositol- and phosphatidylcholine-derived diglycerides in alpha-thrombin-stimulated fibroblasts.. 266. 1991
Lipoprotein (a) regulates plasminogen activator inhibitor-1 expression in endothelial cells. A potential mechanism in thrombogenesis.. 266. 1991
Cellular attachment to thrombospondin. Cooperative interactions between receptor systems.. 266. 1991
Mechanism of inhibition of adenylate cyclase by phospholipase C-catalyzed hydrolysis of phosphatidylcholine. Involvement of a pertussis toxin-sensitive G protein and protein kinase C.. 266. 1991
cAMP stimulates cholesteryl ester clearance to high density lipoproteins in J7774 macrophages.. 266. 1991
Structural and functional properties of the 14-kDa envelope protein of vaccinia virus synthesized in Escherichia coli.. 265. 1990
Cellular mechanisms of the clearance function of type C receptors of atrial natriuretic factor.. 265. 1990
Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.. 265. 1990
Cytokine-enhanced expression of glycoprotein Ib alpha in human endothelium.. 265. 1990
Characterization of a ceramide kinase activity from human leukemia (HL-60) cells. Separation from diacylglycerol kinase activity.. 265. 1990
Accurately initiated, enhancer-dependent transcription by RNA polymerase I in yeast extracts.. 265. 1990
Characterization of a region in mature LamB protein that interacts with a component of the export machinery of Escherichia coli.. 265. 1990
The presence of both the signal sequence and a region of mature LamB protein is required for the interaction of LamB with the export factor SecB.. 265. 1990
A retinoic acid-inducible mRNA from F9 teratocarcinoma cells encodes a novel protease inhibitor homologue.. 265. 1990
Ceramide 1-phosphate, a novel phospholipid in human leukemia (HL-60) cells. Synthesis via ceramide from sphingomyelin.. 265. 1990
Phosphate groups as substrate determinants for casein kinase I action.. 265. 1990
Antagonistic effects of chronic low frequency stimulation and thyroid hormone on myosin expression in rat fast-twitch muscle.. 265. 1990
L-citrulline production from L-arginine by macrophage nitric oxide synthase. The ureido oxygen derives from dioxygen.. 265. 1990
Physiologic 1,2-diacylglycerol levels induce protein kinase C-independent translocation of a regulatory enzyme.. 265. 1990
Resolution of factors required for the initiation of transcription by yeast RNA polymerase II.. 265. 1990
Thrombospondin forms complexes with single-chain and two-chain forms of urokinase.. 265. 1990
Deletion of cytoplasmic sequences of the nerve growth factor receptor leads to loss of high affinity ligand binding.. 265. 1990
Cell-free synthesis of glycosyl-phosphatidylinositol precursors for the glycolipid membrane anchor of Trypanosoma brucei variant surface glycoproteins. Structural characterization of putative biosynthetic intermediates.. 265. 1990
Kinetic evidence of a rapid activation of phosphatidylcholine hydrolysis by Ki-ras oncogene. Possible involvement in late steps of the mitogenic cascade.. 265. 1990
Acidification-dependent dissociation of endocytosed insulin precedes that of endocytosed proteins bearing the mannose 6-phosphate recognition marker.. 265. 1990
Glycolipid precursors for the membrane anchor of Trypanosoma brucei variant surface glycoproteins. I. Can structure of the phosphatidylinositol-specific phospholipase C sensitive and resistant glycolipids.. 265. 1990
Glycolipid precursors for the membrane anchor of Trypanosoma brucei variant surface glycoproteins. II. Lipid structures of phosphatidylinositol-specific phospholipase C sensitive and resistant glycolipids.. 265. 1990
A new class of lysosomal/vacuolar protein sorting signals.. 265. 1990
The human embryonic myosin heavy chain. Complete primary structure reveals evolutionary relationships with other developmental isoforms.. 265. 1990
Genomic structure of an integrin alpha subunit, the leukocyte p150,95 molecule.. 265. 1990
Identification and characterization of human endothelial cell membrane binding sites for tissue plasminogen activator and urokinase.. 265. 1990
Mitogen-stimulated activation of the Na+/H+ antiporter does not regulate S6 phosphorylation or protein synthesis in murine thymocytes or Swiss 3T3 fibroblasts.. 265. 1990
Purification and properties of a kinase from Escherichia coli K-12 that phosphorylates two periplasmic transport proteins.. 265. 1990
Polarized expression of functional rat liver asialoglycoprotein receptor in transfected Madin-Darby canine kidney cells.. 265. 1990
Thermal stability of microsomal glucose-6-phosphatase.. 265. 1990
Identification of an alternate type I insulin-like growth factor receptor beta subunit mRNA transcript.. 264. 1989
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.. 264. 1989
Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages.. 264. 1989
Immunoglobulin E receptor cross-linking induces oscillations in intracellular free ionized calcium in individual tumor mast cells.. 264. 1989
Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents.. 264. 1989
Spontaneous transfer of retinoic acid, retinyl acetate, and retinyl palmitate between single unilamellar vesicles.. 264. 1989
Structure of bovine milk lipoprotein lipase.. 264. 1989
Defective post-translational modification of collagen IV in a mutant F9 teratocarcinoma cell line is associated with delayed differentiation and growth arrest in response to retinoic acid.. 264. 1989
Trifluoperazine stimulates the coordinate degradation of sphingomyelin and phosphatidylcholine in GH3 pituitary cells.. 264. 1989
Thyrotropin-releasing hormone and phorbol esters stimulate sphingomyelin synthesis in GH3 pituitary cells. Evidence for involvement of protein kinase C.. 264. 1989
The calcium signal for Balb/MK keratinocyte terminal differentiation induces sustained alterations in phosphoinositide metabolism without detectable protein kinase C activation.. 264. 1989
Serum alpha 1-antitrypsin deficiency associated with the common S-type (Glu264----Val) mutation results from intracellular degradation of alpha 1-antitrypsin prior to secretion.. 264. 1989
ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.. 264. 1989
Sphingomyelinase action inhibits phorbol ester-induced differentiation of human promyelocytic leukemic (HL-60) cells.. 264. 1989
Macrophages rapidly internalize their tumor necrosis factor receptors in response to bacterial lipopolysaccharide.. 264. 1989
Solubilization and characterization of yeast signal peptidase.. 264. 1989
Effect of sucrose diet on apolipoprotein biosynthesis in rat liver. Increase in apolipoprotein E gene transcription.. 264. 1989
Mechanism of vitamin A movement between rod outer segments, interphotoreceptor retinoid-binding protein, and liposomes.. 264. 1989
Structural significance of the C-terminal amphiphilic helix of interleukin-2.. 264. 1989
Regulation of UDP-glucuronosyltransferase by lipid-protein interactions. Comparison of the thermotropic properties of pure reconstituted enzyme with microsomal enzyme.. 264. 1989
A polarized epithelial cell mutant deficient in translocation of UDP-galactose into the Golgi complex.. 263. 1988
Characterization of the gene and protein of the alpha 1-antitrypsin "deficiency" allele Mprocida.. 263. 1988
Characterization of crystals of xylose isomerase from Streptomyces violaceoniger.. 263. 1988
Structure of the human neutrophil elastase gene.. 263. 1988
Ca2+ and pH responses to sequential additions of mitogens in single 3T3 fibroblasts: correlations with DNA synthesis.. 263. 1988
Phenylalkylamine-sensitive calcium channels in osteoblast-like osteosarcoma cells. Characterization by ligand binding and single channel recordings.. 263. 1988
Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts. Comparison of stimulation by alpha-thrombin and epidermal growth factor.. 263. 1988
Matrix plasminogen activator inhibitor. Modulation of the extracellular proteolytic environment.. 263. 1988
Preliminary x-ray data on crystals of mandelate racemase.. 263. 1988
Purification and characterization of C1, the catalytic subunit of Saccharomyces cerevisiae cAMP-dependent protein kinase encoded by TPK1.. 263. 1988
1,2-Diacylglycerols, but not phorbol esters, activate a potential inhibitory pathway for protein kinase C in GH3 pituitary cells. Evidence for involvement of a sphingomyelinase.. 263. 1988
Purification of a skeletal muscle polypeptide which stimulates choline acetyltransferase activity in cultured spinal cord neurons.. 263. 1988
Myelomonocytic cell lineage expression of the neutrophil elastase gene.. 263. 1988
Candidate glycophospholipid precursor for the glycosylphosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoproteins.. 263. 1988
Site-directed mutagenesis of a residue located in the regulatory site of Escherichia coli aspartate transcarbamoylase. Involvement of lysine 94 in effector binding and the allosteric mechanism.. 263. 1988
High salt activation of recA protein ATPase in the absence of DNA.. 263. 1988
1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells.. 262. 1987
Modulation by recombinant interleukin 1 of synthesis of types I and III collagens and associated procollagen mRNA levels in cultured human cells.. 262. 1987
Structure of the peptide network of pneumococcal peptidoglycan.. 262. 1987
X-ray crystallographic studies of the alanine-specific racemase from Bacillus stearothermophilus. Overproduction, crystallization, and preliminary characterization.. 262. 1987
DNA-mediated gene transfer of a human cell surface 170-kilodalton glycoprotein. Evidence for association with an endogenous murine protein.. 262. 1987
Identification of a ribosomal protein S6 kinase regulated by transformation and growth-promoting stimuli.. 262. 1987
Thyrotropin-releasing hormone and phorbol esters induce phosphatidylcholine synthesis in GH3 pituitary cells. Evidence for stimulation via protein kinase C.. 262. 1987
alpha 1-Antitrypsin nullGranite Falls, a nonexpressing alpha 1-antitrypsin gene associated with a frameshift to stop mutation in a coding exon.. 262. 1987
Properties of p19, a novel cAMP-dependent protein kinase substrate protein purified from bovine brain.. 262. 1987
1,2-Diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action.. 262. 1987
Inhibition of lecithin-cholesterol acyltransferase by diphytanoyl phosphatidylcholine.. 262. 1987
Interactions of arterial cells. Studies on the mechanisms of endothelial cell modulation of cholesterol metabolism in co-cultured smooth muscle cells.. 262. 1987
The effect of dibutyryl cyclic AMP and butyrate on F9 teratocarcinoma cellular retinoic acid-binding protein activity.. 262. 1987
Lecithin:cholesterol acyltransferase. Functional regions and a structural model of the enzyme.. 262. 1987
Tumor necrosis factor increases the number of epidermal growth factor receptors on human fibroblasts.. 262. 1987
Stable binding of recA protein to duplex DNA. Unraveling a paradox.. 262. 1987
recA protein binding to the heteroduplex product of DNA strand exchange.. 262. 1987
Characterization of sulfated glucuronic acid containing glycolipids reacting with IgM M-proteins in patients with neuropathy.. 262. 1987
Catalytic-regulatory subunit interactions and allosteric effects in aspartate transcarbamylase.. 262. 1987
Human apolipoprotein A-I forms thermally stable complexes with anionic but not with zwitterionic phospholipids.. 261. 1986
Identification of a second mutation in the protein-coding sequence of the Z type alpha 1-antitrypsin gene.. 261. 1986
Apolipoprotein A-IV. A determinant for binding and uptake of high density lipoproteins by rat hepatocytes.. 261. 1986
Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues.. 261. 1986
Testosterone-induced changes in contractile protein isoforms in the sexually dimorphic temporalis muscle of the guinea pig.. 261. 1986
The complete cDNA and amino acid sequence of human apolipoprotein B-100.. 261. 1986
Binding of plasminogen to cultured human endothelial cells.. 261. 1986
Release of arachidonate and reduction of oxygen. Independent metabolic bursts of the mouse peritoneal macrophage.. 261. 1986
Binding of plasminogen to extracellular matrix.. 261. 1986
Thrombin-induced vimentin phosphorylation in cultured human umbilical vein endothelial cells.. 261. 1986
Effects of insulin on lipoprotein secretion in rat hepatocyte cultures. The role of the insulin receptor.. 261. 1986
Tissue plasminogen activator and urokinase enhance the binding of plasminogen to thrombospondin.. 261. 1986
Enhanced catabolism of low density lipoproteins in rat by lactosaminated Fab fragment. A new carrier of macromolecules to the liver.. 261. 1986
Lipid-peptide association and activation of lecithin:cholesterol acyltransferase. Effect of alpha-helicity.. 261. 1986
Immune interferon suppresses levels of procollagen mRNA and type II collagen synthesis in cultured human articular and costal chondrocytes.. 261. 1986
c-fos and c-myc gene activation, ionic signals, and DNA synthesis in thymocytes.. 261. 1986
Herpesvirus infection prevents activation of cytoplasmic cholesteryl esterase in arterial smooth muscle cells.. 261. 1986
Inhibition of ubiquitin-dependent proteolysis by non-ubiquitinatable proteins.. 261. 1986
Expression and secretion of biologically active human atrial natriuretic peptide in Saccharomyces cerevisiae.. 261. 1986
Biochemical properties of the heme oxygenase inhibitor, Sn-protoporphyrin. Interactions with apomyoglobin and human serum albumin.. 261. 1986
DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.. 261. 1986
Origin of apolipoprotein A-I polymorphism in plasma.. 260. 1985
Isolation and characterization of the human apolipoprotein A-II gene. Electron microscopic analysis of RNA:DNA hybrids, nucleotide sequence, identification of a polymorphic MspI site, and general structural organization of apolipoprotein genes.. 260. 1985
The structure of the human apolipoprotein C-II gene. Electron microscopic analysis of RNA:DNA hybrids, complete nucleotide sequence, and identification of 5' homologous sequences among apolipoprotein genes.. 260. 1985
An increase in prolyl-4-hydroxylase activity occurs during the retinoic acid-induced differentiation of mouse teratocarcinoma stem cell lines F9 and P19.. 260. 1985
The identification of N-linked oligosaccharides on the human CR2/Epstein-Barr virus receptor and their function in receptor metabolism, plasma membrane expression, and ligand binding.. 260. 1985
Heme binding to murine erythroleukemia cells. Evidence for a heme receptor.. 260. 1985
Interaction of human plasma lecithin:cholesterol acyltransferase and venom phospholipase A2 with apolipoprotein A-I recombinants containing nonhydrolyzable diether phosphatidylcholines.. 260. 1985
Activation of immobilized plasminogen by tissue activator. Multimolecular complex formation.. 260. 1985
Activation of lecithin cholesterol acyltransferase by human apolipoprotein E in discoidal complexes with lipids.. 260. 1985
Identification of a novel ganglioside on erythrocytes with blood group Cad specificity.. 260. 1985
Murine macrophage tumors are a source of a 260,000-dalton acetyl-low density lipoprotein receptor.. 260. 1985
Altered cholesteryl ester cycle is associated with lipid accumulation in herpesvirus-infected arterial smooth muscle cells.. 260. 1985
Direct evidence that burst but not sustained secretion of prolactin stimulated by thyrotropin-releasing hormone is dependent on elevation of cytoplasmic calcium.. 260. 1985
Human liver fatty acid binding protein cDNA and amino acid sequence. Functional and evolutionary implications.. 260. 1985
Acyl chain and headgroup specificity of human plasma lecithin:cholesterol acyltransferase. Separation of matrix and molecular specificities.. 260. 1985
Arachidonic acid inhibits thyrotropin-releasing hormone-induced elevation of cytoplasmic free calcium in GH3 pituitary cells.. 260. 1985
Monoclonal antibodies against bovine milk lipoprotein lipase. Characterization of an antibody specific for the apolipoprotein C-II binding site.. 260. 1985
Ribonucleotide reductase activity and deoxyribonucleoside triphosphate metabolism during the cell cycle of S49 wild-type and mutant mouse T-lymphoma cells.. 260. 1985
The gene encoding the beta-subunit of rat luteinizing hormone. Analysis of gene structure and evolution of nucleotide sequence.. 259. 1984
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine.. 259. 1984
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.. 259. 1984
Low-density lipoprotein receptor binding determinants switch from apolipoprotein E to apolipoprotein B during conversion of hypertriglyceridemic very-low-density lipoprotein to low-density lipoproteins.. 259. 1984
Hysteretic regulation of Ustilago rec1 protein during synapsis.. 259. 1984
Characterization of a transformation-sensitive protein in the extracellular matrix of chicken embryo fibroblasts.. 259. 1984
13C NMR studies of the thermal properties of a model high density lipoprotein. Apolipoprotein A-I-dimyristoylphosphatidylcholine complex.. 259. 1984
Ca2+ ionophores affect phosphoinositide metabolism differently than thyrotropin-releasing hormone in GH3 pituitary cells.. 259. 1984
Conformational changes in the receptors for epidermal growth factor and asialoglycoproteins induced by the mildly acidic pH found in endocytic vesicles.. 259. 1984
Preliminary X-ray crystallographic studies of pig kidney fructose-1,6-bisphosphatase.. 259. 1984
Complex formation of platelet membrane glycoproteins IIb and IIIa with the fibrinogen D domain.. 259. 1984
Mammalian brain phosphoproteins as substrates for calcineurin.. 259. 1984
The calcium signal and phosphatidylinositol breakdown in 2H3 cells.. 259. 1984
The mechanism of the calcium signal and correlation with histamine release in 2H3 cells.. 259. 1984
Selection and characterization of F9 teratocarcinoma stem cell mutants with altered responses to retinoic acid.. 259. 1984
Enzymatic basis of macrophage activation. Kinetic analysis of superoxide production in lysates of resident and activated mouse peritoneal macrophages and granulocytes.. 259. 1984
Mutator phenotype in a mutant of S49 mouse T-lymphoma cells with abnormal sensitivity to thymidine.. 259. 1984
Purification and properties of nuclease gamma from Ustilago maydis.. 259. 1984
Aging and 3,4-diaminopyridine alter synaptosomal calcium uptake.. 258. 1983
Correlation of thrombin-induced glycoprotein V hydrolysis and platelet activation.. 258. 1983
Analysis of the 3' end of the human pro-alpha 2(I) collagen gene. Utilization of multiple polyadenylation sites in cultured fibroblasts.. 258. 1983
The x-ray structure of the periplasmic galactose binding protein from Salmonella typhimurium at 3.0-A resolution.. 258. 1983
Purification of human platelet calcium-activated protease. Effect on platelet and endothelial function.. 258. 1983
Action of lipoprotein lipase on mixed triacylglycerol/phosphatidylcholine monolayers. Activation by apolipoprotein C-II.. 258. 1983
The introduction of specific sites for heavy metal binding in a crystalline protein.. 258. 1983
Free cytoplasmic calcium concentration and the mitogenic stimulation of lymphocytes.. 258. 1983
Apolipoprotein E mediates uptake of Sf 100-400 hypertriglyceridemic very low density lipoproteins by the low density lipoprotein receptor pathway in normal human fibroblasts.. 258. 1983
Human plasma lipoprotein [a]. Structural properties.. 258. 1983
Interaction of synthetic N-5-dimethylaminonaphthalene-1-sulfonyl-apolipoprotein C-II peptides with lipoprotein lipase.. 258. 1983
Purification and properties of uroporphyrinogen decarboxylase from human erythrocytes. A single enzyme catalyzing the four sequential decarboxylations of uroporphyrinogens I and III.. 258. 1983
Acetylcholine and oxidative metabolism in septum and hippocampus in vitro.. 258. 1983
Arterial neutral cholesteryl esterase. A hormone-sensitive enzyme distinct from lysosomal cholesteryl esterase.. 258. 1983
Thyrotropin-releasing hormone stimulates rapid loss of phosphatidylinositol and its conversion to 1,2-diacylglycerol and phosphatidic acid in rat mammotropic pituitary cells. Association with calcium mobilization and prolactin secretion.. 258. 1983
Copy number of a human type I alpha 2 collagen gene.. 257. 1982
Early increases in phospholipid methylation are not necessary for the mitogenic stimulation of lymphocytes.. 257. 1982
A comparative study of heme degradation by NADPH-cytochrome c reductase alone and by the complete heme oxygenase system. Distinctive aspects of heme degradation by NADPH-cytochrome c reductase.. 257. 1982
Purification and properties of bovine spleen heme oxygenase. Amino acid composition and sites of action of inhibitors of heme oxidation.. 257. 1982
The occurrence of molecular interactions among NADPH-cytochrome c reductase, heme oxygenase, and biliverdin reductase in heme degradation.. 257. 1982
The oxidative degradation of heme c by the microsomal heme oxygenase system.. 257. 1982
Kinetics and mechanism of the spontaneous transfer of fluorescent phospholipids between apolipoprotein-phospholipid recombinants. Effect of the polar headgroup.. 257. 1982
Localization and processing of outer membrane and periplasmic proteins in Escherichia coli strains harboring export-specific suppressor mutations.. 257. 1982
Metal ion-mediated regulation of heme oxygenase induction in cultured avian liver cells.. 257. 1982
Glutathione depletion sensitizes tumor cells to oxidative cytolysis.. 257. 1982
Regulation of elastin synthesis in developing sheep nuchal ligament by elastin mRNA levels.. 257. 1982
Incorporation of defined cholesteryl esters into lipoproteins using cholesteryl ester-rich microemulsions.. 257. 1982
Beta protein of bacteriophage lambda promotes renaturation of DNA.. 256. 1981
Reassembled model lipoproteins. Lipid dynamics in recombinants of human apolipoprotein A-II and dimyristoylphosphatidylcholine.. 256. 1981
Purification and properties of a topoisomerase from Ustilago maydis.. 256. 1981
The cell surface receptor for immunoglobulin E. Effect of tunicamycin on molecular properties of receptor from rat basophilic leukemia cells.. 256. 1981
Demonstration of normal and mutant protein M1 subunits of deoxyGTP-resistant ribonucleotide reductase from mutant mouse lymphoma cells.. 256. 1981
DeoxyATP-resistant ribonucleotide reductase of mutant mouse lymphoma cells. Evidence for heterozygosity for the protein M1 subunits.. 256. 1981
Evidence for genetically independent allosteric regulatory domains of the protein M1 subunit of mouse ribonucleotide reductase.. 256. 1981
Thermodynamics of lipid-protein association. The free energy of association of lecithin with reduced and carboxymethylated apolipoprotein A-II from human plasma high density lipoprotein.. 256. 1981
Procollagen messenger RNA levels and activity and collagen synthesis during the fetal development of sheep lung, tendon, and skin.. 256. 1981
Studies on nuclease alpha from Ustilago maydis.. 256. 1981
Induced circular dichroism of incorporated fluorescent cholesteryl esters and polar lipids as a probe of human serum low density lipoprotein structure and melting.. 256. 1981
Multiple alpha and beta tubulin genes represent unlinked and dispersed gene families.. 256. 1981
Procollagen production and procollagen messenger RNA levels and activity in human lung fibroblasts during periods of rapid and stationary growth.. 256. 1981
Isolation, purification, and partial characterization of platelet membrane glycoproteins IIb and IIIa.. 256. 1981
Synthesis of acetylated human fetal hemoglobin.. 256. 1981
Crystallization of yeast triose phosphate isomerase from polyethylene glycol. Protein crystal formation following phase separation.. 256. 1981
The terminal redundancy of the retrovirus genome facilitates chain elongation by reverse transcriptase.. 256. 1981
The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosine.. 255. 1980
Adrenalectomy enhances the induction of heme oxygenase and the degradation of cytochrome P-450 in liver.. 255. 1980
Dynamics of lipid-protein interactions. Interaction of apolipoprotein A-II from human plasma high density lipoproteins with dimyristoylphosphatidylcholine.. 255. 1980
Purification and characterization of nuclease beta from Ustilago maydis.. 255. 1980
Amylo-1,6-glucosidase/4-alpha-glucanotransferase. Reaction of rabbit muscle debranching enzyme with an active site-directed irreversible inhibitor, 1-S-dimethylarsino-1-thio-beta-D-glucopyranoside.. 255. 1980
Alterations in deoxyribonucleotide metabolism in cultured cells with ribonucleotide reductase activities refractory to feedback inhibition by 2'-deoxyadenosine triphosphate.. 255. 1980
The conformational properties of human plasma apolipoprotein C-II. A spectroscopic study.. 255. 1980
Control of collagen production by human diploid lung fibroblasts.. 255. 1980
The antigenic structure of apolipoprotein A-I in human high density lipoproteins. Radioimmunoassay using surface-specific antibodies.. 255. 1980
Characterization of human high density lipoproteins by zonal ultracentrifugation.. 255. 1980
Effect of cyclic AMP on the intracellular degradation of newly synthesized collagen.. 255. 1980
Isolation and characterization of a 15-kilobase genomic sequence coding for part of the Pro alpha 2 chain of sheep type I collagen.. 255. 1980
The regulatory component of adenylate cyclase from uncoupled S49 lymphoma cells differs in charge from the wild type protein.. 255. 1980
Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.. 255. 1980
Regulation of acetylcholine receptor by cyclic AMP.. 255. 1980
Very low density lipoprotein. Removal of Apolipoproteins C-II and C-III-1 during lipolysis in vitro.. 254. 1979
Biological amine transport in chromaffin ghosts. Coupling to the transmembrane proton and potential gradients.. 254. 1979
Steroid induction of delta-aminolevulinic acid synthase and porphyrins in liver. Structure-activity studies and the permissive effects of hormones on the induction process.. 254. 1979
Contribution of alpha helix formation in human plasma apolipoproteins to their enthalpy of association with phospholipids.. 254. 1979
Biophysical properties of a major membrane phospholipid, dielaidoylphosphatidylethanolamine, found in an Escherichia coli fatty acid auxotroph.. 254. 1979
Virus-specific messenger RNAs in permissive cells infected by avian sarcoma virus.. 254. 1979
The cell surface receptor for immunoglobulin E. II. Properties of the purified biologically active receptor.. 254. 1979
Identification of platelet receptors for prostaglandin I2 and D2.. 254. 1979
Suppression of 3-hydroxy-3-methylglutaryl-CoA reductase by low density lipoproteins produced in vitro by lipoprotein lipase action on nonsuppressive very low density lipoproteins.. 254. 1979
Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis.. 254. 1979
Characterization of mutant subunits of human purine nucleoside phosphorylase.. 253. 1978
Enzymatic conversion of prostaglandin endoperoxide H2 and arachidonic acid to prostacyclin by cultured human endothelial cells.. 253. 1978
Degradation of newly synthesized collagen.. 253. 1978
Association in normal human fibroblasts of elevated levels of adenosine 3':5'-monophosphate with a selective decrease in collagen production.. 253. 1978
Properties and distribution of mammalian skeletal muscle guanylate cyclase. Alterations in denervated and dystrophic muscle.. 253. 1978
Prematurely evoked synthesis and induction of delta-aminolevulinate synthetase in neonatal liver. Evidence for metal ion repression of enzyme formation.. 253. 1978
Heterogeneity of cytochrome P-450s induced by polychlorinated biphenyls.. 252. 1977
Human kidney gamma-glutamyl transpeptidase. Catalytic properties, subunit structure, and localization of the gamma-glutamyl binding site on the light subunit.. 252. 1977
Solubilization and partial purification of heme oxygenase from rat liver.. 252. 1977
Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process.. 252. 1977
Thermodynamics of Ca2+ binding to troponin-C.. 252. 1977
Isolation, chemical characterization, and biophysical properties of three different abnormal lipoproteins: LP-X1, LP-X2, and LP-X3.. 252. 1977
Native heparin from rat peritoneal mast cells.. 252. 1977
Stopped flow kinetics of pyrene transfer between human high density lipoproteins.. 251. 1976
Platelet alpha2-macroglobulin and alpha1-antitrypsin.. 251. 1976
Purification of the pneumococcal N-acetylmuramyl-L-alanine amidase to biochemical homogeneity.. 251. 1976
Evidence of the involvement of an outer membrane protein in DNA initiation.. 251. 1976
A comparative study on the removal of cellular lipids from Landschütz ascites cells by human plasma apolipoproteins.. 250. 1975
Characterization of cell-free synthesis of collagen by lung polysomes in a heterologous system.. 250. 1975
Multiple thermotropic phase transitions in Escherichia coli membranes and membrane lipids. A comparison of results obtained by nitroxyl stearate paramagnetic resonance, pyrene excimer fluorescence, and enzyme activity measurements.. 250. 1975
Specific recognition of choline residues in the cell wall teichoic acid by the N-acetylmuramyl-L-alanine amidase of Pneumococcus.. 250. 1975
The interaction of human plasma glycoaminoglycans with plasma lipoproteins.. 250. 1975
Cobalt stimulation of heme degradation in the liver. Dissociation of microsomal oxidation of heme from cytochrome P-450.. 250. 1975
Removal of Z-lines and alpha-actinin from isolated myofibrils by a calcium-activated neutral protease.. 250. 1975
Macromolecular characterization of muscle membranes. Endogenous membrane kinase and phosphorylated protein substrate from normal and denervated muscle.. 250. 1975
A protein from Ustilago which forms an acid-soluble complex with deoxyribonucleic acid.. 250. 1975
Bovine serum albumin. Study of the fatty acid and steroid binding sites using spin-labeled lipids.. 250. 1975
The primary structure of human plasma high density apolipoprotein glutamine I (ApoA-I). I. The amino acid sequence of cyanogen bromide fragment II.. 250. 1975
The primary structure of human plasma high density apolipoprotein glutamine I (ApoA-I). II. The amino acid sequence and alignment of cyanogen bromide fragments IV, III, and I.. 250. 1975
The degradative effects of porphyrins and heme compounds on components of the microsomal mixed function oxidase system.. 250. 1975
Coordinated incorporation of nascent peptidoglycan and teichoic acid into pneumococcal cell walls and conservation of peptidoglycan during growth.. 250. 1975
Teichoic acid phosphorylcholine esterase. A novel enzyme activity in pneumococcus.. 249. 1974
Macromolecular characterization of muscle membranes. Acetylcholine receptor of normal and denervated muscle.. 249. 1974
Phosphorylation of myelin basic protein.. 249. 1974
The interaction of apolipoprotein-serine with phosphatidylcholine.. 249. 1974
The primary structure of apolopoprotein-serine.. 249. 1974
Lung collagen composition and synthesis. Characterization and changes with age.. 249. 1974
Binding of adenosine diphosphate by isolated membranes from human platelets.. 249. 1974
Human plasma high density lipoprotein. Interaction of the cyanogen bromide fragments from apolipoprotein glutamine II (A-II) with phosphatidylcholine.. 248. 1973
Studies on a nuclease from Ustilago maydis. I. Purification, properties, and implication in recombination of the enzyme.. 248. 1973
Studies on a nuclease from Ustilago maydis. II. Substrate specificity and mode of action of the enzyme.. 248. 1973
Pneumococcal Forssman antigen. A choline-containing lipoteichoic acid.. 248. 1973
Human high density lipoprotein, apolipoprotein glutamine II. The immunochemical and lipid-binding properties of apolipoprotein glutamine II derivatives.. 248. 1973
Macromolecular characterization of muscle membranes. I. Proteins and sialic acid of normal and denervated muscle.. 248. 1973
A comparison of the major apolipoprotein from pig and human high density lipoproteins.. 248. 1973
Iodination of the human platelet membrane. Studies of the major surface glycoprotein.. 248. 1973
Erythrocyte protein phosphorylation.. 248. 1973
Isolation of protein synthesis initiation factors from rabbit liver.. 248. 1973
Initiation of globin synthesis. Preparation and use of reticulocyte ribosomes retaining initiation region messenger ribonucleic acid fragments.. 247. 1972
Studies on the proteins of human platelet membranes.. 247. 1972
The influence of lipid on the conformation of human plasma high density apolipoproteins.. 247. 1972
Induction of hepatic tyrosine aminotransferase by indole amines.. 246. 1971
Inhibition of transmethylations of biogenic amines by S-adenosylhomocysteine. Enhancement of transmethylation by adenosylhomocysteinase.. 246. 1971
Regulation of gal messenger ribonucleic acid synthesis in Escherichia coli by 3',5'-cyclic adenosine monophosphate.. 246. 1971
Regulation of lac transcription in Escherichia coli by cyclic adenosine 3',5'-monophosphate. Studies with deoxyribonucleic acid-ribonucleic acid hybridization and hybridization competition.. 245. 1970
Regulation of lac messenger ribonucleic acid synthesis by cyclic adenosine 3',5'-monophosphate and glucose.. 245. 1970
Choline-containing teichoic acid as a structural component of pneumococcal cell wall and its role in sensitivity to lysis by an autolytic enzyme.. 245. 1970
Regulation of inducible enzyme synthesis in Escherichia coli by cyclic adenosine 3', 5'-monophosphate.. 244. 1969
Biochemical studies of synapses in vitro. 3. Ionic activation of protein synthesis.. 244. 1969
Kinetic studies on rat liver carbamyl phosphate synthetase.. 243. 1968
Purification and kinetic properties of brain orotidine 5'-phosphate decarboxylase.. 243. 1968
Steroid induction of porphyrin synthesis in liver cell culture. II. The effects of heme, uridine diphosphate glucuronic acid, and inhibitors of nucleic acid and protein synthesis on the induction process.. 243. 1968
Steroid induction of porphyrin synthesis in liver cell culture. I. Structural basis and possible physiological role in the control of heme formation.. 242. 1967
Studies on the inhibition of actinomycin biosynthesis by D-valine.. 242. 1967
A SPECTROPHOTOMETRIC ASSAY FOR THIOGALACTOSIDE TRANSACETYLASE.. 240. 1965
Kinase suppressor of Ras signals through Thr269 of c-Raf-1.. 288. 2013
The kinase activity of kinase suppressor of Ras1 (KSR1) is independent of bound MEK.. 288. 2013
Thirty sweet years of GLUT4. 2019
Chaperome heterogeneity and its implications for cancer study and treatment. 2018
Structure and dynamics of ESCRT-III membrane remodeling proteins by high-speed atomic force microscopy. 2023
Lipoprotein trafficking in vascular cells. Molecular Trojan horses and cellular saboteurs. 1997
Diverse transcriptional functions of the multisubunit eukaryotic TFIID complex. 1992

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